Meeting Program
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To view program in "24 hour" time (international) click here. |
| Sunday, April 11 | ||
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| 3:00 - 7:30 PM | Registration | Kokopelli's |
| 6:30 - 7:30 PM | Refreshments | Kokopelli's |
| 7:30 - 9:30 PM |
Keynote Address (Joint) Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn Ballroom |
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Michael F. Good,
Queensland Institute of Medical Research, Australia
Malaria Vaccines: Lessons from Immune Escape Instruct New Strategies |
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Anthony A. James,
University of California, Irvine, USA
Transgenic Strategies for Pathogen Transmission Control |
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| Monday, April 12 | ||
| 7:00 - 8:00 AM | Breakfast | Kokopelli's/Ptarmigan B-C |
| 8:00 - 11:00 AM |
Vector Populations Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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Gerry F. Killeen,
Ifakara Health Research and Development Centre, Tanzania
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Didier Fontenille,
IRD, France
Complexity of the Malaria Vectorial System in Africa |
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Nora J. Besansky,
University of Notre Dame, USA
Chromosome Structural Polymorphism and the Malaria Transmission System |
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Gregory Lanzaro,
University of California, Davis, USA
The Genetic Structure of Anopheles Gambiae Populations |
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William C. Black IV,
Colorado State University, USA
Population Genetics of Aedes aegypti and Dengue Transmission |
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| Following Session is for Malaria (F1) | ||
| 8:00 - 11:15 AM |
Parasite Interactions with the Immune System Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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Kate A. Fitzgerald,
University of Massachusetts Medical School, USA
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Paolo Arese,
University of Torino Medical School, Italy
Effects of Hemozoin and Hemozoin-Generated Molecules on Immune and Non-Immune Host Cells |
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James Brewer,
University of Glasgow, UK
Imaging Infection and Immune Responses in vivo |
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Jean Langhorne,
National Institute for Medical Research, UK
Kinetics of the Immune Response in Mice: Relevance for Human Malaria? |
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Takafumi Tsuboi,
Ehime University, Japan
Sexual Stage Parasites and Transmission-Blocking Antibodies |
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Alice Gray†,
Medical Research Council, Gambia
Short Talk: The Interplay between Treg, IL-2 and T Memory Cells in Malaria |
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Renée M. Tsolis,
University of California, Davis, USA
Short Talk: Malaria Parasite Infection Suppresses Mucosal Responses to Salmonella in the Intestine |
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| 9:20 - 9:40 AM | Coffee Break | Kokopelli's |
| 11:00 AM- 1:00 PM | Poster Setup | Big Horn Ballroom |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 1:00 - 10:00 PM | Poster Viewing | Big Horn Ballroom |
| 2:30 - 4:30 PM |
Workshop 1 |
Big Horn C |
| 2:30 - 3:30 PM |
Special Topics |
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Debaditya Bhattacharya,
Tufts Medical Center, USA
Development of a Reservoir-Targeted Vaccine against Yersinia pestis |
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Ramavati Pal,
Victoria University of Wellington, New Zealand
Insect Glutathione S-transferase Proteome and Insecticide Resistance |
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Linda De Vooght,
Institute of Tropical Medicine, Antwerp, Belgium
Expression of Trypanosome-Development Inhibitory Proteins into the Periplasm of Sodalis glossinidius, a Bacterial Symbiont of the Tsetse Fly |
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| 3:30 - 4:30 PM |
Vector Biology Funding Priorities and Perspectives |
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Adriana Costero-Saint Denis,
National Institute of Allergy and Infectious Diseases, national Institutes of Health, USA
Vector Biology Funding Opportunities at the National Institute of Allergy and Infectious Diseases |
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Inma Penas-Jiminez,
European Commission, CORDIS, Belgium
European Union Funded Research on Vector Biology |
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| 4:30 - 5:00 PM | Coffee Available | Kokopelli's |
| 5:00 - 7:00 PM |
Olfaction, Host Seeking and Behavior Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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Anthony A. James,
University of California, Irvine, USA
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Laurence J. Zwiebel,
Vanderbilt University, USA
Olfactory and Thermosensory Genomics as a Basis for Disrupting Disease Transmission by Vector Mosquitoes |
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Flaminia Catteruccia,
Imperial College London, UK
Molecular Bases of Anopheles gambiae Reproductive Biology: A Laboratory and Field Study |
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Willem Takken,
Wageningen University, The Netherlands
Olfaction and Behavioral Ecology of Disease Vectors |
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| Following Session is for Malaria (F1) | ||
| 5:00 - 7:00 PM |
Recognizing Protective Immunity Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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*
John T. Harty,
University of Iowa, USA
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Robert Sauerwein,
Radboud University, The Netherlands
Complete Immunity after Limited Exposure to P. falciparum in a Controlled Setting |
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Eleanor M. Riley,
London School of Hygiene and Tropical Medicine, UK
Cross-Talk between Innate and Adaptive Immune Cells: Relevance for Assessing Effector Cell Responses to Malaria Vaccines |
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Laurent Renia,
Singapore Immunology Network, Singapore
Mechanisms of Acquired Immunity against Malaria Liver Stage Immunity |
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Nathan W. Schmidt,
University of Iowa, USA
Short Talk: Plasmodium Species and Host Background Genes Profoundly Influence the Threshold of Memory CD8 T Cells Required for Protective Immunity |
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Kokopelli's |
| 7:30 - 10:00 PM |
Poster Session 1 Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn Ballroom |
| Tuesday, April 13 | ||
| 7:00 - 8:00 AM | Breakfast | Kokopelli's/Ptarmigan B-C |
| 8:00 - 11:00 AM |
Insecticides and Resistance Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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*
Elena A. Levashina,
Institut de Biologie Moleculaire et Cellulaire, France
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Hilary Ranson,
Liverpool School of Tropical Medicine, UK
The Molecular Genetics of Insecticide Resistance in Mosquitoes |
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Maureen Coetzee,
University of Witwatersrand, South Africa
Insecticides and Malaria Epidemiology |
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Janet Hemingway,
Liverpool School of Tropical Medicine, UK
Biochemistry of Insecticide Resistance |
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Brian D. Foy,
Colorado State University, USA
The Effects of Anthelmintics on Anthropophilic Mosquitoes in the Lab and Field |
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| Following Session is for Malaria (F1) | ||
| 8:00 - 11:15 AM |
Local Milieu for Host-Parasite Interactions Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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Gareth Turner,
Oxford University, UK
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Ute Frevert,
New York University School of Medicine, USA
Imaging the Immunobiology of Plasmodium in the Liver |
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Fidel P. Zavala,
Johns Hopkins Bloomberg School of Public Health, USA
Development of Memory CD8+ T Cells Against Malaria Liver Stages |
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Nick Crispe,
Seattle Biomedical Research Institute, USA
Immune Responses in the Liver |
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Pierre Buffet,
Pitie-Salpetriere Hospital, France
Erythrocytes Squeezing across Splenic Slits and the Pathogenesis of Plasmodium falciparum Infection |
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Sandra March,
Massachusetts Institute of Technology, USA
Short Talk: Establishment of the Liver Stages of Plasmodium falciparum in a Microscale Human Liver Platform |
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Anne-Marie Zeeman,
Biomedical Primate Research Centre, The Netherlands
Short Talk: An Efficient in vitro Culture System to Study Malaria Dormant Liver Stages |
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| 9:20 - 9:40 AM | Coffee Break | Kokopelli's |
| 11:00 AM- 1:00 PM | Poster Setup | Big Horn Ballroom |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 1:00 - 10:00 PM | Poster Viewing | Big Horn Ballroom |
| 4:30 - 5:00 PM | Coffee Available | Kokopelli's |
| 5:00 - 7:00 PM |
Pathogen Receptors and Cellular Interactions Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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Kenneth D. Vernick,
Institut Pasteur, France
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Robert E. Sinden,
Imperial College London, UK
The Cell Biology of Plasmodium in the Mosquito |
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Kenneth E. Olson,
Colorado State University, USA
Interactions between Arboviruses and the Mosquito’s RNAi Pathway |
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Serap Aksoy,
Yale University School of Medicine, USA
Microbiome Influences on Host Vector Competence |
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| Following Session is for Malaria (F1) | ||
| 5:00 - 7:00 PM |
Parasite Invasion and Arrest Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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Robert Sauerwein,
Radboud University, The Netherlands
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Maria M. Mota,
Instituto de Medicina Molecular, Portugal
Host-Parasite Interactions in the Liver |
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Urszula Krzych,
Walter Reed Army Institute of Research, USA
Memory CD8+ T Cells in Experimental Models of Protective Immunity Induced by Attenuated Plasmodia Sporozoites |
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Richard J. Pleass,
University of Nottingham, UK
Engineering Antibodies for Novel Malaria Vaccines |
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Audrey Gego,
INSERM UMR S 945, France
Short Talk: Identification of New Hepatocyte Factors Involved in Malaria Liver Stage Infection by Large Scale RNAi Screening |
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Kokopelli's |
| 7:30 - 10:00 PM |
Poster Session 2 Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn Ballroom |
| Wednesday, April 14 | ||
| 7:00 - 8:00 AM | Breakfast | Kokopelli's/Ptarmigan B-C |
| 8:00 - 11:00 AM |
Host-Parasite Evolution Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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Gerry F. Killeen,
Ifakara Health Research and Development Centre, Tanzania
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Louis Lambrechts,
Institut Pasteur, France
Genetic Specificity of Interactions between Dengue Viruses and Mosquito Vectors |
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Andrew Read,
Pennsylvania State University, USA
Evolution-Proofing Existing Malaria Control Tools |
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Brian P. Lazzaro,
Cornell University, USA
Evolution of Anopheles Immune Defense Genes |
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Tanya L. Russell†,
Ifakara Health Institute, Tanzania
Talk Title to be Determined |
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Marc A.T. Muskavitch†,
Boston College, USA
Short Talk: Implementation of a High-Density SNP Genotyping Array for the Vector Mosquito Anopheles gambiae for Analysis of Population Structure and Genetic Mapping |
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| Following Session is for Malaria (F1) | ||
| 8:00 - 11:15 AM |
Malarial Disease: Contribution of Host Response Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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*
Maria M. Mota,
Instituto de Medicina Molecular, Portugal
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Gareth Turner,
Oxford University, UK
The Pathology of Human Malaria |
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Kate A. Fitzgerald,
University of Massachusetts Medical School, USA
The Innate Immune Response to Malaria |
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Patrick E. Duffy,
National Institute of Allergy and Infectious Diseases, USA
Malarial Disease and the Placenta |
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Nick M. Anstey,
Menzies School of Health Research, Australia
Disease caused by Plasmodium vivax |
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Andrew E. Armitage†,
Weatherall Institute of Molecular Medicine, UK
Short Talk: Plasmodium falciparum Infected Erythrocytes Induce Hepcidin (HAMP) mRNA Synthesis by Peripheral Blood Mononuclear Cells |
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Ana Paula Freitas do Rosario,
National Institute for Medical Research, UK
Short Talk: TH1 CD4+ T Cells are the Main Source of Protective IL-10 Against Immune-Mediated Pathology during Plasmodium Chabaudi AS Infection |
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| 9:20 - 9:40 AM | Coffee Break | Kokopelli's |
| 11:00 AM- 1:00 PM | Poster Setup | Big Horn Ballroom |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 1:00 - 10:00 PM | Poster Viewing | Big Horn Ballroom |
| 2:30 - 4:30 PM |
Workshop 2: Special Topics |
Big Horn C |
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*
Elena A. Levashina,
Institut de Biologie Moleculaire et Cellulaire, France
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Luciano Andrade Moreira,
University of Queensland, Australia
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya and Plasmodium |
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Kostas Iatrou,
National Centre for Scientific Research, Greece
Volatile Constituents of Plant Origin Bind Selectively Various Odorant Binding Proteins of the Malaria Vector Anopheles gambiae and Act as Strong Repellents Capable of Interfering with the Vector’s Host Seeking and Blood Feeding Activities |
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Igor Sharakhov,
Virginia Polytechnic Institute, USA
Genome Landscape and Evolutionary Plasticity of Chromosomes in Malaria Mosquitoes |
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Judith Lum Ndamukong,
University of Buea, Cameroon
Biting Densities and Transmission Potential of Malaria Vectors in the Mount Cameroon Region at Contrasting Altitudinal Zones |
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Hirotaka Kanuka,
Obihiro University of Agriculture and Veterinary Medicine, Japan
Midgut Bacteria Regulates Plasmodium Development in Malaria Vector Anopheles Mosquitoes |
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Short Talk to be Chosen from Abstracts,
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| Following Workshop is for Malaria (F1) | ||
| 2:30 - 4:30 PM |
Workshop Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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*
Patrick E. Duffy,
National Institute of Allergy and Infectious Diseases, USA
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Angela A. Aggrey,
University of Rochester Medical Center, USA
The Role of Platelets in Experimental Cerebral Malaria |
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Noah S. Butler,
University of Iowa, USA
Key Immune-Effector Molecules Differentially Regulate Memory CD8 T Cell-Mediated Immunity Against Liver Stage P. berghei versus P. yoelii Infection |
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Aubrey Cunnington,
London School of Hygiene and Tropical Medicine, UK
Impairment of Host Defence during Malaria: A Possible Consequence of Heme Oxygenase-1 Induction |
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Olivia Finney†,
Seattle Biomedical Research Institute, USA
Comparison of Immune Responses to Protective and Non Protective DNA Vaccines using Novel Liver Stage Antigens |
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Lei Shong Lau,
University of Melbourne, Australia
Blood-Stage Plasmodium berghei Infection Generates Parasite-Specific Effector and Memory CD8+ T Cell Responses |
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Jenni C. Lawton,
National Institute for Medical Research, UK
The cir Multi-Gene Family of Plasmodium chabaudi |
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Demba Sarr,
University of Georgia, USA
Differential Pregnancy Outcomes of Plasmodium chabaudi AS-Infected A/J and C57BL/6 Mice |
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| 4:30 - 5:00 PM | Coffee Available | Kokopelli's |
| 5:00 - 7:00 PM |
Insect Immunity Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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*
Anthony A. James,
University of California, Irvine, USA
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Elena A. Levashina,
Institut de Biologie Moleculaire et Cellulaire, France
Complement-Like System in Immune Responses of Anopheles gambiae |
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Alexander S. Raikhel,
University of California, Riverside, USA
Mosquito Immune Signaling Pathways |
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Kenneth D. Vernick,
Institut Pasteur, France
Mapping and Functional Dissection of Mosquito Resistance to Plasmodium |
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| Following Session is for Malaria (F1) | ||
| 5:00 - 7:00 PM |
Systems Biology of the Immune Response Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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Dyann F. Wirth,
Harvard University, USA
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Bali Pulendran,
Emory University, USA
Predicting Protective Immune Responses to Vaccines |
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Peter D. Crompton,
National Institutes of Health, USA
Using Protein Microarrays to Probe the Human Antibody Response to Plasmodium falciparum |
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Johanna P. Daily,
Albert Einstein College of Medicine, USA
Parasite Transcriptional Respones to Physiologic Conditions |
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Erica M. Pasini,
Biomedical Primate Research Centre, The Netherlands
Short Talk: Identification of a Small Exported Protein Strongly Associated with Sequestration through Proteomics of the Membranes of P. berghei Infected Erythrocytes (iRBCs) |
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Kokopelli's |
| 7:30 - 10:00 PM |
Poster Session 3 Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn Ballroom |
| Thursday, April 15 | ||
| 7:00 - 8:00 AM | Breakfast | Kokopelli's/Ptarmigan B-C |
| 8:00 - 11:00 AM |
Control Strategies - Current and Future I Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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*
Kenneth D. Vernick,
Institut Pasteur, France
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Andrea Crisanti,
Imperial College of Science Technology and Medicine, UK
HEG-Mediated Gene Drive in Caged Anopheles Gambiae Mosquito Populations |
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Gerry F. Killeen,
Ifakara Health Research and Development Centre, Tanzania
Ecology: A Prerequisite for Malaria Elimination and Eradication |
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Catherine Bourgouin,
Institut Pasteur, France
Vector Targeted Immunological Control of Malaria Transmission |
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Christian Lengeler,
Swiss Tropical and Public Health Institute, Switzerland
From Technology Development and Field Validation to Large-Scale Vector Control Interventions |
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| Following Session is for Malaria (F1) | ||
| 8:00 - 11:15 AM |
Multigene Families: Role in Immunity and Pathology Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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*
Jean Langhorne,
National Institute for Medical Research, UK
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Dyann F. Wirth,
Harvard University, USA
Genetic Diversity in Plasmodia |
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Joseph D. Smith,
Seattle Biomedical Research Institute, USA
Structure-Function of DBL Domains and Vaccine Design |
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Peter R. Preiser,
Nanyang Technological University, Singapore
Understanding the Biological Role of Small Variant Antigens in Plasmodium |
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Lars Hviid,
University of Copenhagen, Denmark
The Naturally Acquired Human Antibody Response to Plasmodium falciparum Variant Surface Antigens |
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Benoit Gamain,
Pasteur Institute, France
Short Talk: Full-Length Extracellular Region of the var2CSA Variant of PfEMP1 is Required for Specific, High-Affinity Binding to CSA |
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Marissa G. Vignali†,
Seattle Biomedical Research Institute, USA
Short Talk: Differential Gene Expression in P. falciparum Field Samples of Variable Disease Severity |
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| 9:20 - 9:40 AM | Coffee Break | Kokopelli's |
| 11:00 AM- | On Own for Lunch and Recreation | |
| 4:30 - 5:00 PM | Coffee Available | Kokopelli's |
| 5:00 - 7:00 PM |
Control Strategies - Current and Future II Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn C |
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*
Kenneth D. Vernick,
Institut Pasteur, France
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Bart Knols,
Academic Medical Centre, Amsterdam, The Netherlands
Entomopathogenic Fungi as a Malaria Biocontrol Tool |
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Gregor J. Devine,
Ifakara Health Institute, Tanzania
Adult Mosquitoes as Insecticide Delivery Agents |
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Luke S. Alphey,
Oxitec Ltd, UK
Sterile Insects for Vector Control |
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| Following Session is for Malaria (F1) | ||
| 5:00 - 7:00 PM |
Inducing Optimal Protective Responses with Vaccines Registered attendees for this meeting can view Abstracts for this session starting on 03/11/2010 |
Big Horn B |
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*
Michael F. Good,
Queensland Institute of Medical Research, Australia
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John T. Harty,
University of Iowa, USA
Quantifying CD8 T Cell Mediated Anti-Plasmodium Immunity and Protective Immunity after Attenuated Parasite Immunization |
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Joanna Kubler Kielb,
National Institutes of Health, USA
A Bicomponent Pre-Erythrocytic Investigational Malaria Vaccine |
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Philip Bejon,
University of Oxford, UK
Immunity Induced by a Partially Protective Vaccine |
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Julie Healer,
Walter and Eliza Hall Institute of Medical Research, Australia
Short Talk: Preclinical Development of a Combined Vaccine Against Bloodstage P. falciparum Malaria |
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| 7:00 - 8:00 PM | Social Hour w/ Lite Bites | Jack's |
| 8:00 - 11:00 PM | Entertainment | Jack's |
| Friday, April 16 | ||
| Departure | ||
| *=Session Chair †=Speaker invited, not yet responded. | ||
Keystone Symposia would like to thank the sponsor of this meeting for their generous support:
We gratefully acknowledge the generous grant for this conference provided by:
National Institutes of Health
National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI088817-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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