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Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity

Scientific Organizers:
Franck Mauvais-Jarvis, Deborah Clegg,
and Arthur P. Arnold

Date Dates:
March 19-22, 2017

Location Location:
Tahoe City, California, USA
Submit abstracts for short talk consideration by December 19, 2016 at midnight US MT.

Save on registration fees through January 18, 2017.

There are fundamental aspects of metabolic homeostasis that are regulated differently in males and females, and influence both the development of diabetes and obesity and the response to pharmacological intervention. Still, most preclinical researchers avoid studying female rodents due to the added complexity of research plans. The consequence is the generation of data that risks being relevant to only half of the population. This is a timely moment to study sex differences in diseases as NIH leadership has asked scientists to consider sex as a biological variable in pre-clinical research, to ensure that women get the same benefit of medical research as men. The goal of this meeting is to fill a need in the scientific community by connecting groups of scientists who normally would not interact. This group includes investigators studying sex differences, the role of sex hormones, the systems biology of sex and the genetic contribution of sex chromosomes to metabolic homeostasis and diseases. Leaders from the pharmaceutical industry will present their views on sex-specific drug discovery. The meeting is expected to generate new knowledge and ideas on the importance of gender biology and medicine from a molecular standpoint to the population level, and to provide the methods to study them. It is intended to be a catalyst of a process that will lead to gender-specific treatments of metabolic diseases.

In summary, the conference will:

  • Connect scientists across disciplines who normally would not have an opportunity to meet, including basic scientists, clinical investigators and pharmaceutical industry leaders;
  • Generate awareness, new scientific knowledge and ideas regarding the importance of the role of gender and sex hormones and how they impact biology and medicine from a molecular standpoint to the population level;
  • Train the next generation of scientists in considering sex as a biological variable in preclinical research and in designing studies to conduct pre-clinical research on sex differences.

The three-day conference will consist of sessions focused on the following topics:

  • Sex Differences in Metabolic Homeostasis
  • Workshop: Designing Pre-Clinical Studies to Conduct Research on Sex Differences
  • Estrogens and Metabolic Homeostasis
  • Androgen and Metabolic Homeostasis
  • Genetics, Metabolomics and Systems Biology of Sex Differences
  • Drug Design and Gender-Specific Medicine

The conference will be of interest to those working in the fields of:
Drug Discovery • Endocrinology • Genetics • Metabolism & Metabolic Diseases • Metabolomics • Molecular Biology • Precision Medicine • Systems Biology


Keystone Symposia conferences offer:

  • A retreat-like atmosphere
  • An intimate environment
  • Interactive poster sessions
  • Exchange of ideas and experiences
  • Access to experts during and after talks
  • Short talk slots for breakthroughs and up-and-coming/junior investigators
  • Free time for recreation and collaboration-building

Confirmed Speakers
(as of Dec 8, 2016)

Arthur P. Arnold, University of California, Los Angeles, USA
Miriam Bredella, Massachusetts General Hospital, USA
Chawnshang Chang, University of Rochester, USA
Deborah Clegg, Cedars-Sinai Medical Center, USA
Marc-Andre Cornier, University of Colorado, USA
Jayne S. Danska, Hospital for Sick Children Research Institute, Canada
Richard D. DiMarchi, Indiana University, USA
Andrea Dunaif, Northwestern University Feinberg School of Medicine, USA
Susan K. Fried, Icahn School of Medicine at Mount Sinai, USA
Jean-François Gautier, Paris VII University School of Medicine, France
Andrea L. Hevener, University of California, Los Angeles, USA
Holly A. Ingraham, University of California, San Francisco, USA
Cecilia Lindgren, Oxford University, UK
Miguel López, Universidad de Santiago de Compostela, Spain
Franck Mauvais-Jarvis, Tulane University Health Sciences Center, USA
Christopher B. Newgard, Duke University Medical Center, USA
David C. Page*, Whitehead Institute for Biomedical Research, USA
Karen Reue, University of California, Los Angeles, USA
Charles T. Roberts, Oregon National Primate Research Center, USA
Alan J. Russell, GlaxoSmithKline plc., USA
James Trevaskis, MedImmune, USA

*Keynote speaker

For the most up-to-date list of speakers and talks, click here:


How to Register


Toll-Free: 800-253-0685

Outside USA & Canada:
+1 970-262-1230


Conference Deadlines

Abstract Deadline:
Dec 19, 2016

Discounted Registration Deadline: Jan 18, 2017

Additional Information

  • Deadlines are at midnight US Mountain Time.
  • Discounted abstract submission and discounted registration save 50 USD and 150 USD, respectively, on later fees. Short talk speakers will be chosen from abstracts received by the "Abstract Deadline" for the meeting.
  • Please note that the first advertised meeting date is the date of arrival and registration, and the last date that of the last organized sessions.

Visit our website for the program details and to plan your travel so as not to miss any sessions.

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