Eldorado Hotel & Spa Floorplan

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This meeting took place in 2017


Here are the related meetings in 2019:
Windows on the Brain: Formation and Function of Synapses and Circuits and their Disruption in Disease (A6)

For a complete list of the meetings for the upcoming/current season, see our meeting list, or search for a meeting.

Connectomics (X2)


Organizer(s) Olaf Sporns, Danielle Bassett and Jeremy Freeman
March 5—8, 2017
Eldorado Hotel & Spa • Santa Fe, New Mexico USA
Discounted Abstract Deadline: Nov 3, 2016
Abstract Deadline: Dec 18, 2016
Scholarship Deadline: Nov 3, 2016
Discounted Registration Deadline: Jan 11, 2017

Sponsored by Merck & Co., Inc. and Takeda Pharmaceutical Company Limited


Summary of Meeting:
The emerging field of connectomics comprises extensive efforts to map patterns of brain connectivity, to represent these patterns with the tools of network science, and to explore the relation of brain connectivity and dynamics to behavior and cognition. Importantly, these efforts span multiple scales of brain organization, from synaptic connectivity among individual neurons, to comprehensive maps of circuits, neuronal populations, and projections among brain regions. An integrative multi-scale framework for mapping, analyzing and modeling connectome data sets is lacking. This Keystone Symposia meeting aims to narrow this important gap, by: 1) Fostering scientific exchange among otherwise siloed researchers studying connectomes in different organisms at different scales with different measurement techniques; 2) Promoting approaches that apply across scales, for example by leveraging the tools of network science; 3) Emphasizing the need to move beyond descriptive accounts of connectomes, to model-based prediction and control; 4) Providing a unique opportunity for pre- and postdoctoral trainees to engage with connectomics leaders and present their work. Anticipated outcomes include a multi-scale framework for description, prediction and control of connectomes; innovative computational methods for statistical analysis and modeling of connectome data sets; and new collaborations among participating researchers and trainees. The meeting will have transformative impact by creating new relationships among investigators and by seeding a new integrative research agenda centered on the structure and dynamics of brain connectivity.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Sunday, March 5 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Wednesday, March 8 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Thursday, March 9 in order to fully experience the meeting.

SUNDAY, MARCH 5

16:00—20:00
Arrival and Registration

Eldorado Lounge
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Eldorado Lounge

MONDAY, MARCH 6

07:00—08:00
Breakfast

Anasazi Ballroom
08:00—09:30
Welcome and Keynote Session (Joint)
Meeting has ended...abstracts no longer viewable online.

Eldorado Grand Ballroom
* Tony Koleske, Yale University, USA

Hollis T. Cline, The Scripps Research Institute, USA
Wiring Circuits in the Visual System

* Danielle S. Bassett, University of Pennsylvania, USA

Hongkui Zeng, Allen Institute for Brain Science, USA
Cell Type-Based Brain-Wide Connectomics

Coffee Break

09:50—11:30
Building Connectomes at Micro, Meso and Macroscales
Meeting has ended...abstracts no longer viewable online.

Eldorado B
* Danielle S. Bassett, University of Pennsylvania, USA

Moritz Helmstaedter, Max Planck Institute for Brain Research, Germany
Cerebral Cortex Connectomics

Alard Roebroeck, Maastricht University, Netherlands
Imaging Human Connectome Networks at the Mesoscale

Justus Kebschull, Cold Spring Harbor, USA
Short Talk: A Single Neuron Resolution Mesoscale Connectome of the Mouse Cortex Obtained Rapidly by Barcoded RNA Sequencing

Claus C. Hilgetag, University Medical Center Eppendorf, Hamburg University, Germany
Short Talk: Linking Macroscale Brain Connectivity and Intrinsic Brain Architecture

09:50—12:00
Cell Types of the Nervous System
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Kristin Scott, University of California, Berkeley, USA

Paola Arlotta, Harvard University, USA
Cell Fate Determination and Maintenance in Mammalian Cortex

Arnold R. Kriegstein, University of California, San Francisco, USA
Developmental Lineages Contributing to Neuronal Diversity in the Human Cortex

Jens Hjerling Leffler, Karolinska Institute, Sweden
Single Cell Analysis of the Juvenile Telencephalon

Geoffrey Stanley, Stanford University, USA
Short Talk: Discrete and Continuous Transcriptomic Identities of Striatal Neurons

Chan Lek Tan, University of California, San Francisco, USA
Short Talk: Molecular Identification of Thermoregulatory Neurons in the Hypothalamus using Activity-Dependent Ribosome Profiling

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Anasazi Ballroom
13:00—22:00
Poster Viewing

Anasazi Ballroom
14:30—16:30
Workshop 1

Eldorado B
* Olaf Sporns, Indiana University, USA

Anjali Vijay Dhobale, Pennsylvania State University, USA
Functional Connectivity Analysis of Fluorescent Calcium Imaging from Micro-Tissue Engineered Axonal Tracts

Liang Yuchi, Pennsylvania State University, USA
Bidirectional Growth Model of Micro-Tissue Engineered Neuronal Networks (micro-TENNs)

Shelli Kesler, University of Texas, USA
Disruption of the Functional Connectome in a 5XFAD Transgenic Mouse Model of Alzheimer's Disease

Amina Ann Qutub, University of Texas, USA
Identifying Design Principles of Differentiating Neural Cells

Ankit Khambhati, University of Pennsylvania, USA
Functional Subgraphs of Brain Networks Modulate Cognitive Control Processes between Task States

Bill Shannon, BioRankings, USA
Connectome Regression

Ioannis Pappas, University of Cambridge, UK
Spatial Complexity of Brain Connectivity during Altered Consciousness

UnCheol Lee, University of Michigan, USA
Network Mechanisms of Progressive, Abrupt, Early, and Delayed Emergences from Unconsciousness

14:30—16:30
Workshop 1: Circuit Function and Dysfunction and Disease

Eldorado A
* A. Kimberley McAllister, University of California, Davis, USA

Summer Thyme, Harvard University, USA
Zebrafish Brain Activity Phenotypes Unify Schizophrenia-Associated Genes

Alan R. Mardinly, University of California, Berkeley, USA
3D All-Optical Control of Functionally Defined Neurons with Cellular Resolution and Sub-Millisecond Precision

Michelle Antoine, University of California, Berkeley, USA
Increased Excitation-Inhibition (E-I) Ratio without Elevated Network Spiking in Autism Spectrum Disorder (ASD)

Xin Jin, Harvard University, USA
In vivo Investigation of Cortical Cell Type Development in Autism and Intellectual Disability: A Converged Heterogeneity?

Gabrielle L. Sell, Johns Hopkins University School of Medicine, USA
Reducing Ectopic Expression of Ephexin5 Ameliorates Cognitive Impairment in an Alzheimer Model

Ileana Lorenzini, Barrow Neurological Institute, USA
Synaptic Deficits in C9ORF72-ALS/FTD Patient-Derived iPS Neurons and in vivo Models of C9

Kuan Hong Wang, NIMH, National Institutes of Health, USA
Dysfunction and Repair of Mesofrontal Dopaminergic Circuits in Neuropsychiatric Models

Chris Zimmerman, University of California, San Francisco, USA
The Neural Dynamics and Circuit Architecture Underlying Thirst

16:30—17:00
Coffee Available

Concourse
17:00—17:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Yimin Zou, University of California, San Diego, USA

David D. Ginty, HHMI/Harvard Medical School, USA
The Development and Functional Organization of Touch Circuitry

17:00—19:00
Network Structure and Variability
Meeting has ended...abstracts no longer viewable online.

Eldorado B
Anna Beyeler, University of Bordeaux, France
Functional Diversity in Amygdala Circuits

Tom Vaissiere, The Scripps Research Institute, USA
Short Talk: Structural and Functional Whole-Brain Mapping in a Model of Syngap1-Related Brain Disorders

17:45—19:15
Cellular Morphogenesis in the Nervous System
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Hollis T. Cline, The Scripps Research Institute, USA

John G. Flanagan, Harvard Medical School, USA
Local Translation in Axon Guidance

Yimin Zou, University of California, San Diego, USA
Signaling Pathways in Growth Cone Guidance and Synapse Formation

Haruki Takeuchi, University of Tokyo, Japan
Short Talk: Patterned, but not Synchronous Spontaneous Activity of Olfactory Neurons Regulates Olfactory Receptor-Specific Axon Sorting

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Anasazi Ballroom
19:30—22:00
Poster Session 1

Anasazi Ballroom

TUESDAY, MARCH 7

07:00—08:00
Breakfast

Anasazi Ballroom
08:30—11:00
Patterns of Brain Dynamics
Meeting has ended...abstracts no longer viewable online.

Eldorado B
* Randy McIntosh, University of Toronto, Canada

Matteo Carandini, University College London, UK
Recording from 10,000 Neurons to Test Two Theories of Cortex

Sridevi V. Sarma, Johns Hopkins University, USA
Fragility in Epileptic Networks: The Epileptogenic Zone

Coffee Break

Michael Breakspear, Queensland Institute of Medical Research, Australia
Brain Waves: Mechanisms of Metastable Cortical Dynamics

Anees Abrol, University of New Mexico, USA
Short Talk: Replicability of Dynamic Connectivity Patterns in Resting State of Human Brain

Ben D. Fulcher, Monash University, Australia
Short Talk: Structural Connectome Topology Relates to Regional BOLD Signal Dynamics

08:00—11:15
Synapse Development and Function
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Tony Koleske, Yale University, USA

Jessica A. Cardin, Yale School of Medicine, USA
Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits

Michael E. Greenberg, Harvard Medical School, USA
Activity-Dependent Plasticity

Coffee Break

Elly Nedivi, Massachusetts Institute of Technology, USA
Visualizing Synapse Structural Dynamics in vivo

Bernardo L. Sabatini, Harvard Medical School, USA
Activity-Dependent Regulation of Synaptic Plasticity

Eunkyung Lie, Institute for Basic Science, South Korea
Short Talk: Regulation of Excitatory Synapses by the Synaptic Adhesion Molecule SALM4

Matthew B. Dalva, Thomas Jefferson University, USA
Short Talk: Synaptic Nanomodules Underlie the Organization and Plasticity of Spine Synapses

11:15—17:00
On Own for Lunch

11:15—13:00
Poster Setup

Anasazi Ballroom
13:00—22:00
Poster Viewing

Anasazi Ballroom
14:30—16:30
Workshop 2: Identification and Characterization of Cells and Projections

Eldorado A
* Yimin Zou, University of California, San Diego, USA

Ken Burke, University of California, San Francisco, USA
Input-Specific Dopaminergic Modulation of Gain at Long-Range Inputs to Medial Prefrontal Cortex

Aaron D. Levy, Yale University, USA
SHP2 Inhibits GluN2B-Containing NMDA Receptor Function and Regulates Learning and Memory

David E. Leib, University of California, San Francisco, USA
Molecular Identification of Active Neurons Defined by FOS Expression or Phosphorylation of ERK1/2

Jinyue Liu, Harvard Medical School, USA
Transcriptional Determination of Laminar Identity for Retinal Ganglion Cell Dendrites

Pushpanathan Muthuirulan, NICHD, National Institutes of Health, USA
Mapping Neurotransmitter Receptors to the Active Synaptic Circuits by Fluorescence Complementation

Smita Yadav, University of California, San Francisco HMI, USA
Role of Autism Susceptibility Gene TAOK2 Kinase and its Novel Substrates in Synaptogenesis

Ryoji Amamoto, Harvard University, USA
Adult Axolotis Can Regenerate Original Neuronal Diversity in Response to Brain Injury

16:30—17:00
Coffee Available

Concourse
17:00—19:00
Behavior and Cognitive Architectures
Meeting has ended...abstracts no longer viewable online.

Eldorado B
* Sridevi V. Sarma, Johns Hopkins University, USA

Sophie Aimon, University of California, San Diego, USA
Probing Large-Scale Network Dynamics at High Speed in the Brain of Behaving Flies

Randy McIntosh, University of Toronto, Canada
Moving from Mental States to Mental Processes via Connectome-Based Brain Simulation

Damien Fair, Oregon Health and Science University, USA
Typical and Atypical Development of Human Brain Networks

Marta Costa, University of Cambridge, UK
Short Talk: Leveraging Light-Level Image Data to Build the Mushroom Body Connectome of the Adult Fly

17:00—19:00
Support Cells and ECM
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Matthew B. Dalva, Thomas Jefferson University, USA

Cagla Eroglu, Duke University Medical Center, USA
Control of Synaptic Connectivity by Astrocytes

Yi Zuo, University of California, Santa Cruz, USA
Astrocytic Contributions to Synaptic and Learning Abnormalities in a Mouse Model of Fragile X Syndrome

Tony Koleske, Yale University, USA
Intersection of Adhesion- and Activity-Based Mechanisms in the Control of Synapse Maturation and Stability

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Anasazi Ballroom
19:30—22:00
Poster Session 2

Anasazi Ballroom

WEDNESDAY, MARCH 8

07:00—08:00
Breakfast

Anasazi Ballroom
08:00—08:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Eldorado B
* Michael Breakspear, Queensland Institute of Medical Research, Australia

Edward T. Bullmore, University of Cambridge, UK
Economical Brain Networks in Health and Disease

08:45—11:30
Big Data Challenges and Integration
Meeting has ended...abstracts no longer viewable online.

Eldorado B
Randal Burns, Johns Hopkins University, USA
Data-Intensive Applications: The OpenConnectome Project

Coffee Break

Neda Jahanshad, IGC, INI, Keck School of Medicine University of Southern California, USA
Mapping Brain Variability and Heritability in Human Populations

Danielle S. Bassett, University of Pennsylvania, USA
Structural and Functional Network Drivers of Individual Differences in Cognition

Manish Saggar, Stanford University, USA
Short Talk: Revealing the Shape of Brain Dynamics during “Ongoing” Cognition

Robyn Miller, Mind Research Network, USA
Short Talk: Statistical Stationarity, Temporal Epochs and fMRI Network Dynamics

08:00—11:15
Neural Circuit Development and Function
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Yimin Zou, University of California, San Diego, USA

Liqun Luo, Stanford University, USA
Wiring Specificity in Neural Circuit Assembly

Sreekanth Chalasani, The Salk Institute for Biological Studies, USA
Neuromodulatory Control of Chemosensory Processing in C. elegans

Coffee Break

Kristin Scott, University of California, Berkeley, USA
Feeding Decisions in Drosophila

Zhigang He, Children's Hospital, Boston, USA
Rebuilding Functional Circuits after Injury

Nicole Calakos, Duke University Medical Center, USA
Short Talk: Striatal circuit mechanisms for Habit and Compulsion

Chen Ran, Stanford University, USA
Short Talk: Spinal Cord Circuit for Thermosensation and its Reorganization in Persistent Pain

11:30—17:00
On Own for Lunch

14:30—16:30
Workshop 2

Eldorado B
* Olaf Sporns, Indiana University, USA

Navin Pokala, New York Institute of Technology, USA
Quantitative Prediction of Neural Network State Behaviors

Julio I. Chapeton, National Institutes of Health, USA
Functional Networks Exhibit Consistent Timing and Stable Connectivity in the Human Brain

Payel Das, IBM, USA
Relationship between Static and Dynamic Brain Functional Connectivity in Autism Spectrum Disorders

Karolina Finc, Nicolaus Copernicus University, Poland
Default Mode Network Role in Global Workspace Formation During Increasing Cognitive Demands

Leonardo Gollo, QIMR Berghofer Medical Research Institute, Australia
Hierarchical Timescales in the Brain: Structure-Dynamics Interplay, Perturbations, and Tuning Curves

Jin Liu, Beijing Normal University, China
Chronnectome Fingerprinting: Identifying Individuals Using Dynamic Functional Brain Connectivity

Michael Craig, University of Cambridge, UK
Network-level structural optimality using Nash Equilibrium Network Models

Melanie Weber, Princeton University, USA
Curvature-based Analysis of Connectivity Structure in Brain Networks

14:30—16:30
Workshop 3: Synapse Development

Eldorado A
* A. Kimberley McAllister, University of California, Davis, USA

Kenneth Myers, Emory University, USA
LIM and SH3 Protein-1 Regulates Dendritic Spine Development

Akiyoshi Uezu, Duke University, USA
Unraveling the Inhibitory Synapse Proteome in vivo

Thomas Schaffer, Johns Hopkins University School of Medicine, USA
PKCepsilon Inhibits Dendritic Spine Development in Hippocampal Neurons by Activating the Developmentally-Regulated RhoA GEF Exphexin5

Anna R. Moore, Brandeis University, USA
Rem2 Regulates Distinct Homeostatic Mechanisms in Visual Circuit Plasticity

Xiangling Meng, Baylor College of Medicine, USA
Neurexophilin 4 Regulates the Function of Synapses in the Central Nervous System

Vinita Bharat, European Neuroscience Institute Göttingen, Germany
Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4

Clarissa Waites, Columbia University, USA
Essential Role for Parkin in AMPA and NMDA Receptor Trafficking and Signaling

Ogul Ersin Uner, University of Pennsylvania, USA
Investigating Molecular Compensation in SAP97 Neuronal Knockout Mice

16:30—17:00
Coffee Available

Concourse
17:00—18:45
Computational Models and Theory
Meeting has ended...abstracts no longer viewable online.

Eldorado B
* Randal Burns, Johns Hopkins University, USA

Thomas Dean, Google, USA
Learning Mesoscale Models of Neural Computation

Olaf Sporns, Indiana University, USA
From Connectomics to Network Neuroscience

17:00—19:00
Neuronal Dysfunction Function in Disease
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* Kristin Scott, University of California, Berkeley, USA

Ricardo E. Dolmetsch, Novartis Institutes for BioMedical Research, USA
iPSC Models for Drug Discovery for Neurodevelopmental, Psychiatric and Degenerative Disorders

Guo-li Ming, University of Pennsylvania, USA
Modeling 15q11.2 Genetic Risk for Psychiatric Disorders

A. Kimberley McAllister, University of California, Davis, USA
Immune Signaling in Neurons in Schizophrenia and Autism

Seth Taylor, University of California, San Diego, USA
Short Talk: Micro-RNA 218 Regulates Hippocampal Development through Age-Dependent Effects on Early Postnatal Synchronized Activity

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Eldorado B
19:00—19:15
Meeting Wrap-Up: Outcomes and Future Directions
Meeting has ended...abstracts no longer viewable online.

Eldorado A
* A. Kimberley McAllister, University of California, Davis, USA

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Anasazi Ballroom
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Anasazi Ballroom

THURSDAY, MARCH 9

 
Departure


*Session Chair †Invited, not yet responded.


We gratefully acknowledge support for this conference from:


Directors' Fund

These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.

Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Merck & Co., Inc. Takeda Pharmaceutical Company Limited

We gratefully acknowledge the generous grant for this conference provided by:


National Institutes of Health

Grant No. 1R13NS100143-01

“Research reported in this publication was supported by the National Institutes of Health under Award Number NS100143. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”

We gratefully acknowledge additional support for this conference from:

CEDARLANE

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Google Foundation

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

NeuroscientistNews

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations

If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Yvonne Psaila, Director, Marketing and Communications, Email: yvonnep@keystonesymposia.org,
Phone:+1 970-262-2676