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This meeting took place in 2019



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Digital Health: From Science to Application (A5)


Organizer(s) Geoffrey S. Ginsburg, Sue Siegel and Eric D. Perakslis
January 21—25, 2019
Keystone Resort • Keystone, Colorado USA
Discounted Abstract Deadline: Oct 16, 2018
Abstract Deadline: Oct 24, 2018
Scholarship Deadline: Oct 16, 2018
Discounted Registration Deadline: Nov 27, 2018

Sponsored by Biogen and Janssen R&D: Pharmaceutical Companies of Johnson & Johnson

Summary of Meeting:
This conference is the first digital health meeting to focus specifically on the scientific foundations and health applications of digital technologies. Taking a novel sensor or new device from concept to clinic is remarkably complex, and the technologies are evolving rapidly. Digital technology offers novel capabilities that have great potential to drive chronic disease understanding and management at both an individual and population level, including the ability to deliver real-time interventions that can be connected to a healthcare system, in a community setting or in limited-resource settings. The increased use of digital capture devices has become a universal part of everyday life; however, more research is needed to provide evidence that wearables and even more sophisticated implantable medical devices will transform healthcare delivery quality and costs. This Keystone Symposia conference focuses on: 1) The scientific/medical gaps in knowledge and opportunities to fill them; 2) Required methodologies for medical and technical validation; and 3) Specifics of data and knowledge management. The conference explores the landscape at the intersection of digital technologies, molecular/genomic data and healthcare data by examining how these data streams can interface to enable precision health, drive research (patient-reported outcomes, continuous phenotypes) and impact clinical care (monitoring, feedback, adherence). The conference aims to enhance participants’ understanding of the state of the art for capturing digital phenotyping and of consumer/patient access and comprehension, regulatory jurisdiction, health care provider/system readiness, clinical utility, personal utility, integration with the electronic health record, quality standards and ethical considerations. It brings together clinicians, scientists, technology innovators, health economists and regulators to discuss and develop the new models of cross-disciplinary collaboration and business that will be required to deliver quality digital health strategies and solutions, and to illuminate areas of synergy between the academic, public and private sectors to inform a research agenda for the next five years.

View Scholarships/Awards
No registration fees are used to fund entertainment or alcohol at this conference

Conference Program    Print  |   View meeting in 12 hr (am/pm) time


The meeting will begin on Monday, January 21 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Friday, January 25 with a closing plenary session from 17:00 to 19:00, followed by a social hour and entertainment. We recommend return travel on Saturday, January 26 in order to fully experience the meeting.

MONDAY, JANUARY 21

16:00—20:00
Arrival and Registration

Longs Peak Foyer
18:00—20:00
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Longs Peak Foyer

TUESDAY, JANUARY 22

07:00—08:00
Breakfast

Longs Peak
08:00—09:00
Keynote Speaker and Fireside Chat

Grays Peak
* Geoffrey S. Ginsburg, Duke University, USA

* Sue Siegel, GE Ventures, USA
Digital: The Future Is Now

09:00—11:30
The Science Behind Digital Technology
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Geoffrey S. Ginsburg, Duke University, USA

Miah Wander, Microsoft, USA
Toward Digital Health at Scale: Sensing and Analytics

Coffee Break

Aydogan Ozcan, University of California, Los Angeles, USA
Innovation at the Interface of Photonics and Medicine to Support Digital Health

Calum A. MacRae, Brigham & Women's Hospital, USA
Biology: Proximal Measures and Patient Trajectories

Bibi Bielekova, NIAID, National Institutes of Health, USA
Short Talk: Smartphone Level Test Measures Neurological Disability in Several Domains

Sergio E. Baranzini, University of California, San Francisco, USA
Short Talk: A Computational Method to Integrate Electronic Health Records and a Multi-Scale Biomedical Knowledge Network for Automated Stratification and Follow-Up of Patients

11:30—17:00
On Own for Lunch

11:30—13:00
Poster Setup

Longs Peak
13:00—22:00
Poster Viewing

Longs Peak
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Digital Health and Genomics Convergence
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Geoffrey S. Ginsburg, Duke University, USA

Isaac S. Kohane, Harvard Medical School, USA
SMART Technologies and Health Care

David Shaywitz, Takeda Ventures, Inc, USA
Invention Isn’t Implementation: Figuring Out How to Use Data Science and Technology (DST) in Pharma R&D

James Lu, Helix, USA
Digitizing the Genome for Personal, Research and Clinical Uses

Lee Stopak, Ada Health GmbH, Germany
Short Talk: Digital Phenotyping and Contextualized Genomics within Ada, an AI Patient and Clinical Decision Support Tool

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs Peak
19:30—22:00
Poster Session 1

Longs Peak

WEDNESDAY, JANUARY 23

07:00—08:00
Breakfast

Longs Peak
08:00—11:00
Applications of Digital Health to Personal Wellness
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Sue Siegel, GE Ventures, USA

Erwin P. Böttinger, Hasso-Plattner-Institut für Digital Engineering GmbH, Germany
Hasso Plattner Institute (HPI) Digital Health: Creating Citizen-Centred Solutions for Better Health

Jason M. Langheier, Zipongo, USA
Zipongo Foodsmart and Foodscripts: Digital Nutrition Platform for Health Outcomes

Coffee Break

Ida Sim, University of California, San Francisco, USA
Making Sense of Health Data

Anna Diane, Duke University, USA
Short Talk: Enabling Precision Health in Type 2 Diabetes through Mobile Health Technologies

Jonas Duss, Kaia Health, Germany
Short Talk: Agile Development of a Digital Therapeutic to Treat Back Pain (Kaia): Implementing User Feedback for Increased

Amina Ann Qutub, University of Texas, USA
Short Talk: Digitizing Brain Health: From Neurogenesis to Daily Behaviors

11:00—17:00
On Own for Lunch

13:00—22:00
Poster Viewing

Longs Peak
16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Applications of Digital Health Technologies to Drug Development
Meeting has ended...abstracts no longer viewable online.

Grays Peak
Alessio Signorini, Evidation Health, USA
Digital Phenotyping and Post-Approval Monitoring of Drugs

* Eric D. Perakslis, Harvard Medical School, USA
Digital Biomarkers and More Efficient Clinical Drug Development

Andrea (Andy) Coravos, Elektra Labs, USA
The Rise of Ethical Digital Medicine: Biomarkers, Diagnostics and Therapeutics

Chris Benko, Koneksa Health, USA
Using Wearable Technologies to Enable Novel Endpoint Development and Remote Data Collection in Clinical Trials

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs Peak
19:30—22:00
Poster Session 2

Longs Peak

THURSDAY, JANUARY 24

07:00—08:00
Breakfast

Longs Peak
08:00—08:45
Keynote Address
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Eric D. Perakslis, Harvard Medical School, USA

Christopher M. Danforth, University of Vermont, USA
Measuring Happiness and Health using Social Media

08:45—11:15
Developing Cohort Studies with Multiscale Multidimensional Data
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Eric D. Perakslis, Harvard Medical School, USA

Gregory Marcus, University of California, San Francisco, USA
eCohorts and eTrials: The Health eHeart Study and the Eureka Mobile Research Platform

Coffee Break

Eric Dishman, National Institutes of Health, USA
Accelerating Precision Health for All of Us: The All of Us Research Program

Robert Califf, Duke University, Verily Life Sciences, USA
Can We Map the Human Health Condition?

Dan Coster, Tel-Aviv University, Israel
Short Talk: A Model for Early Detection of Cancer Risk Based on Routine Check-Up Data Using Random Forest of Survival Analysis Trees for Left-Truncated and Right Censored Data

Jae-Seung Yun, Catholic University of Korea, South Korea
Short Talk: Development and Validation of a Risk Prediction Model for Severe Hypoglycemia in Adult Patients with Type 2

11:15—17:00
On Own for Lunch

13:00—22:00
Poster Viewing

Longs Peak
14:30—16:30
Workshop and Panel: Strategies for Successful Digital Health Implementation
• To gain a better understanding of current digital health integration and explore how the field can learn from successful examples as it moves forward.
• Identify areas where digital health applications are currently experiencing challenges and/or bottlenecks in clinical implementation and discuss potential solutions from various stakeholder perspectives.

Grays Peak
* John Rumsfeld, American College of Cardiology, USA
Welcome and Introduction

* Sanjeev Bhavnani, Scripps Clinic & Research Foundation, USA
The State of Digital Health Implementation: Where Are We Now and How Are We Going to Succeed Given the Challenges?

* Ryan J. Shaw, Duke University, USA
Practical Solutions in Digital Health Integration for Consideration: Stakeholder Perspectives

Calum A. MacRae, Brigham & Women's Hospital, USA
Clinical Integration

Ida Sim, University of California, San Francisco, USA
EHRs as Facilitators of Digital Health Technology

Nicholas Petrick, U.S. Food and Drug Administration, USA
Regulatory

Elizabeth Burr, , USA
Consumer

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—19:00
Specific Disease Applications of Digital Health
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Oliver Keown, GE Ventures, USA

Paul Dagum, Mindstrong Health, USA
Digital Phenotypes of Psychiatric Morbidity

Helen L. Egger, New York University, USA
Autism and Beyond

Aenor Sawyer, University of California, San Francisco, USA
The Clinical-Digital Innovator

Alexandra Boukhvalova, University of Maryland School of Medicine, USA
Short Talk: Identifying and Quantifying Neurological Disorders via Smartphone

19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs Peak

FRIDAY, JANUARY 25

07:00—08:00
Breakfast

Longs Peak
08:00—11:00
Regulatory and Reimbursement Pathways
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* Oliver Keown, GE Ventures, USA

Nicholas Petrick, U.S. Food and Drug Administration, USA
Assessment of Machine Learning-Based Decision Aids: FDA’s Regulatory Framework and Evaluation Methods

Elizabeth Burr, , USA
The Future of Digital Health Innovation

Coffee Break

Sean C. McConnell, American Medical Association, USA
Driving the Future of Digital Health

Christopher Khoury, American Medical Association, USA
Short Talk: Industry, Scientific, and Clinical Drivers of AI in Healthcare

Emma Lidington, Radboud University Medical Center, Netherlands
Short Talk: Evaluating a Digital Tool for Supporting Breast Cancer Patients: The Protocol for a Prospective Randomized Controlled Trial

11:00—17:00
On Own for Lunch

16:30—17:00
Coffee Available

Longs Peak Foyer
17:00—18:45
Digital Health – What's the Value Proposition?
Meeting has ended...abstracts no longer viewable online.

Grays Peak
* John Rumsfeld, American College of Cardiology, USA
The Challenge of Digital Transformation for Healthcare

Paul McNamee, University of Aberdeen, UK
Bang for the Buck: A Guide to Health Economics Analysis for Digital Health

Eun Kyong Shin, University of Tennessee Health Science Center, USA
Short Talk: Sociomarkers and Biomarkers: Predictive Modeling in Identifying Pediatric Asthma Patients at Risk of Hospital Revisits

18:45—19:00
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Meeting has ended...abstracts no longer viewable online.

Grays Peak
19:00—20:00
Social Hour with Lite Bites
No registration fees are used to fund alcohol served at this function.

Longs Peak
20:00—23:00
Entertainment
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Longs Peak

SATURDAY, JANUARY 26

 
Departure


*Session Chair †Invited, not yet responded.



We gratefully acknowledge support for this conference from:


Directors' Fund


These generous unrestricted gifts allow our Directors to schedule meetings in a wide variety of important areas, many of which are in the early stages of research.

Click here to view all of the donors who support the Directors' Fund.



Keystone Symposia thanks our Sponsors for generously supporting this meeting:

Biogen Janssen R&D: Pharmaceutical Companies of Johnson & Johnson

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:



Elektra Labs


Helix


Koneksa Health


Microsoft Corporation


Mindstrong Health


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:


Click here to view more of these organizations


Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:


Click here to view more of these organizations


If your organization is interested in joining these entities in support of Keystone Symposia, please contact: Sarah Lavicka, Director of Development, Email: sarahl@keystonesymposia.org,
Phone:+1 970-262-2690

Click here for more information on Industry Support and Recognition Opportunities.

If you are interested in becoming an advertising/marketing in-kind partner, please contact:
Nick Dua, Senior Director, Communications, Email: nickd@keystonesymposia.org,
Phone:+1 970-262-1179