Single Cell Biology: Pushing New Frontiers in the Life Sciences

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Monday, May 04 | 4:00PM - 8:00PM
Arrival and Registration


Monday, May 04 | 6:00PM - 8:00PM
Welcome Mixer
No registration fees are used to fund alcohol served at this function.

Tuesday, May 05 | 8:00AM - 8:30AM
Poster Setup
Room: Passi Perduti


Tuesday, May 05 | 8:30AM - 5:00PM
Poster Viewing
Room: Passi Perduti


Tuesday, May 05 | 8:30AM - 9:30AM
Welcome and Keynote Address
Room: Auditorium

Speaker 1 of 1
Eileen E.M. Furlong, European Molecular Biology Laboratory, Germany
Dissecting Regulatory Principles of Embryonic Development One Cell at a Time

Tuesday, May 05 | 9:30AM - 12:00PM
Interrogating Disease Models at Single Cell
Room: Auditorium

Speaker 1 of 6
Barbara Treutlein, ETH Zürich, Switzerland
Understanding Organoids by Disassembling and Analysing Component Lineages Using Single-Cell RNA Sequencing

Tuesday, May 05 | 9:30AM - 12:00PM
Interrogating Disease Models at Single Cell
Room: Auditorium


Coffee Break

Tuesday, May 05 | 9:30AM - 12:00PM
Interrogating Disease Models at Single Cell
Room: Auditorium

Speaker 3 of 6
Ido Amit, Weizmann Institute, Israel
The Power of ONE: Immunology in the Age of Single Cell Genomics

Tuesday, May 05 | 9:30AM - 12:00PM
Interrogating Disease Models at Single Cell
Room: Auditorium

Speaker 4 of 6
Maike Sander, University of California, San Diego, USA
Insights into Pancreatic Islet Cell Gene Regulation and Disease Mechanisms of Diabetes from Single-Cell Analyses

Tuesday, May 05 | 9:30AM - 12:00PM
Interrogating Disease Models at Single Cell
Room: Auditorium

Speaker 5 of 6
Teresa G. Krieger, Berlin Institute of Health / Charité, Germany
Short Talk: Patient-Derived PDAC Organoids Recapitulate Tumor Cell State Heterogeneity and Functional Hierarchy in vitro

Tuesday, May 05 | 9:30AM - 12:00PM
Interrogating Disease Models at Single Cell
Room: Auditorium

Speaker 6 of 6
Erin F. McCaffrey, Stanford University, USA
Short Talk: Constructing an Atlas of Human Tuberculosis Granulomas with Multiplexed Ion Beam Imaging

Tuesday, May 05 | 12:00PM - 1:00PM
Lunch


Tuesday, May 05 | 1:00PM - 3:00PM
Poster Session 1
Room: Passi Perduti


Tuesday, May 05 | 3:00PM - 4:30PM
Workshop 1: Emerging Technologies for Unbiased Single Cell A
nalysis
Room: Auditorium

Speaker 1 of 6
Charles Ansong, Pacific Northwest National Laboratory, USA

Tuesday, May 05 | 3:00PM - 4:30PM
Workshop 1: Emerging Technologies for Unbiased Single Cell A
nalysis
Room: Auditorium

Speaker 2 of 6
† TongSeng Lim, Menarini Biomarkers Singapore, Singapore
Application of Single Cell Analysis to Disease Diagnosis

Tuesday, May 05 | 3:00PM - 4:30PM
Workshop 1: Emerging Technologies for Unbiased Single Cell A
nalysis
Room: Auditorium

Speaker 3 of 6
Andreas-David Brunner, Max Planck Institute of Biochemistry, Germany
Leveraging Trapped Ion Mobility Spectrometry and PASEF for Single Cell Proteomics

Tuesday, May 05 | 3:00PM - 4:30PM
Workshop 1: Emerging Technologies for Unbiased Single Cell A
nalysis
Room: Auditorium

Speaker 4 of 6
David Ruff, Mission Bio, USA
An Innovative Multimodal Single-Cell High-Throughput Microfluidic Workflow to Characterize Cell States and Pathway Responses

Tuesday, May 05 | 3:00PM - 4:30PM
Workshop 1: Emerging Technologies for Unbiased Single Cell A
nalysis
Room: Auditorium

Speaker 5 of 6
Christopher S. McGinnis, University of California, San Francisco, USA
Advances and Applications of Single-Cell Genomics Sample Multiplexing Technology

Tuesday, May 05 | 3:00PM - 4:30PM
Workshop 1: Emerging Technologies for Unbiased Single Cell A
nalysis
Room: Auditorium

Speaker 6 of 6
Francesca Meschi, 10x Genomics, USA
Massively-Parallel Simultaneous Profiling of the Transcriptomic and Epigenomic Landscape at Single-Cell Resolution

Tuesday, May 05 | 4:30PM - 5:00PM
Coffee Available
Room: Passi Perduti


Tuesday, May 05 | 5:00PM - 7:00PM
Single Cell Computational Biology to Molecular Mechanisms
Room: Auditorium

Speaker 1 of 5
Sarah Teichmann, Wellcome Sanger Institute, UK
Cell States and Transcriptional Programmes in the Adult Human Heart

Tuesday, May 05 | 5:00PM - 7:00PM
Single Cell Computational Biology to Molecular Mechanisms
Room: Auditorium

Speaker 2 of 5
Fabian Theis, Helmholtz Zentrum München, Germany
Computational Approaches in Single Cell Trajectory Analysis and Modeling

Tuesday, May 05 | 5:00PM - 7:00PM
Single Cell Computational Biology to Molecular Mechanisms
Room: Auditorium

Speaker 3 of 5
Matthias Mann, Max Planck Institute of Biochemistry, Germany
Proteomics and Systems Biology in the Age of Single Cell Analysis

Tuesday, May 05 | 5:00PM - 7:00PM
Single Cell Computational Biology to Molecular Mechanisms
Room: Auditorium

Speaker 4 of 5
Ivan Gesteira Costa Filho, RWTH Aachen, Germany
Short Talk: Chromatin Accessibility and Transcription Factor Activity Estimation on Single Cells

Tuesday, May 05 | 5:00PM - 7:00PM
Single Cell Computational Biology to Molecular Mechanisms
Room: Auditorium

Speaker 5 of 5
Hyun Jae Lee, QIMR Berghofer, Australia
Short Talk: Transcriptome and Epigenome Dynamics of CD4+ T Cells during Malaria Maps Progressive Transition from Effector to Memory

Tuesday, May 05 | 7:00PM - 7:00PM
On Own for Dinner


Wednesday, May 06 | 8:00AM - 8:30AM
Poster Setup
Room: Passi Perduti


Wednesday, May 06 | 8:00AM - 5:00PM
Poster Viewing
Room: Passi Perduti


Wednesday, May 06 | 8:30AM - 11:30AM
Development and Cell Fate at Single Cell Resolution I
Room: Auditorium

Speaker 1 of 6
Jeffrey A. Whitsett, Cincinnati Children's Hospital Medical Center, USA
LungMAP: Systems Biology Approaches Supporting Study of Perinatal and Postnatal Lung Development and Disease

Wednesday, May 06 | 8:30AM - 11:30AM
Development and Cell Fate at Single Cell Resolution I
Room: Auditorium

Speaker 2 of 6
Nikolaus Rajewsky, Max Delbruck Center for Molecular Medicine, Germany
Design Principles of Gene Expression by Single Cell-Sequencing

Wednesday, May 06 | 8:30AM - 11:30AM
Development and Cell Fate at Single Cell Resolution I
Room: Auditorium


Coffee Break

Wednesday, May 06 | 8:30AM - 11:30AM
Development and Cell Fate at Single Cell Resolution I
Room: Auditorium

Speaker 4 of 6
Alexander F. Schier, Harvard University, USA
Cellular Biographies: Reconstructing Zebrafish Development

Wednesday, May 06 | 8:30AM - 11:30AM
Development and Cell Fate at Single Cell Resolution I
Room: Auditorium

Speaker 5 of 6
Sten Linnarsson, Karolinska Institutet, Sweden
Molecular Architecture and Development of the Human Brain

Wednesday, May 06 | 8:30AM - 11:30AM
Development and Cell Fate at Single Cell Resolution I
Room: Auditorium

Speaker 6 of 6
Stefano Piccolo, University of Padua, Italy
Combined Single-Cell and Histopathology Datasets Reveal Spalial Location of Glioblastoma Stem Cells and New Plasticity Determinants

Wednesday, May 06 | 11:45AM - 12:30PM
Lunch
Room: Passi Perduti


Wednesday, May 06 | 12:30PM - 3:00PM
Poster Session 2
Room: Passi Perduti


Wednesday, May 06 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 1 of 5
† Nikos Karaiskos, Germany
Gene Expression Cartography

Wednesday, May 06 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 2 of 5
Tamim Abdelaal, Delft University of Technology, Netherlands
SpaGE: Spatial Gene Enhancement using scRNA-seq

Wednesday, May 06 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 3 of 5
Constanza Martinez, McGill University, Canada
Spatial Mapping of Single-Cell RNA Sequencing Populations in Primary and Metastatic Breast Cancer

Wednesday, May 06 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 4 of 5
Steffen Rulands, Max Planck Institute for the Physics of Complex Systems, Germany
From Sequence to Space and Time: Inferring Emergent Epigenetic Processes From Single-Cell Multi-Omics

Wednesday, May 06 | 3:00PM - 4:30PM
Workshop 2
Room: Auditorium

Speaker 5 of 5
† Anne L. Plant, National Institute of Standards and Technology, USA
Fluctuations in Fluorescent Reporters of Gene Expression Provide Insight Into the Thermodynamics of Cellular Networks

Wednesday, May 06 | 4:30PM - 5:00PM
Coffee Available
Room: Passi Perduti


Wednesday, May 06 | 5:00PM - 7:00PM
Spatially-Resolved Omics at Single Cell Resolution
Room: Auditorium

Speaker 1 of 5
Julia Laskin, Purdue University, USA
Spatial Lipidomics and Metabolomics by Mass Spectrometry Imaging

Wednesday, May 06 | 5:00PM - 7:00PM
Spatially-Resolved Omics at Single Cell Resolution
Room: Auditorium

Speaker 2 of 5
Bernd Bodenmiller, University of Zürich, Switzerland
Highly Multiplexed Imaging of Tissues with Subcellular Resolution by Imaging Mass Cytometry

Wednesday, May 06 | 5:00PM - 7:00PM
Spatially-Resolved Omics at Single Cell Resolution
Room: Auditorium

Speaker 3 of 5
Prisca Liberali, Friedrich Miescher Institute for Biomedical Research, Switzerland
Regenerative Landscape of Intestinal Organoids

Wednesday, May 06 | 5:00PM - 7:00PM
Spatially-Resolved Omics at Single Cell Resolution
Room: Auditorium

Speaker 4 of 5
Lars Borm, Karolinska Institutet, Sweden
Short Talk: Transcriptome Mapping With High Spatial Throughput by RNA Transfer to a Surface in the Human Embryo

Wednesday, May 06 | 5:00PM - 7:00PM
Spatially-Resolved Omics at Single Cell Resolution
Room: Auditorium

Speaker 5 of 5
Fabian Coscia, NNF Center for Protein Research, University of Copenhagen, Denmark
Short Talk: Deep Visual Proteomics – Image Guided Cell Characterization to Unravel Functional Cell Heterogeneity at the Single Cell Level

Wednesday, May 06 | 7:00PM - 7:00PM
On Own for Dinner


Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 1 of 9
Massimiliano Pagani, La Fondazione Istituto Nazionale di Genetica Molecolare - INGM, Italy
Deciphering the Tumor Microenvironment by Multiomics Analyses

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 2 of 9
Evan W. Newell, Fred Hutchinson Cancer Research Center, USA
Using Antigen Specificity to Parse the High Dimensional Profiles of Tumor Infiltrating T Cells

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium


Coffee Break

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 4 of 9
Peter Lichter, Deutsches Krebsforschungszentrum, Germany
Experiences in Assessing Intra-Tumor Heterogeneity by Single Cell Sequencing

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 5 of 9
Kara L. Davis, Stanford University, USA
Single-Cell Developmental Classification of B Cell Precursor Acute Lymphoblastic Leukemia Using Mass Cytometry at Diagnosis Reveals Predictors of Relapse

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 6 of 9
Jeffrey M. Granja, Stanford, USA
Short Talk: Single-Cell Multiomic Analysis Identifies Regulatory Programs in Mixed-Phenotype Acute Leukemia

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 7 of 9
Matteo Maria Naldini, Fondazione Telethon, Italy
Short Talk: Deconvolution of Acute Myeloid Leukemia Intra-Tumor Heterogeneity Through Single-Cell RNA Sequencing

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 8 of 9
Laura Llaó Cid, German Cancer Research Center, Germany
Short Talk: Deciphering the Complexity of Tumor-Associated T Cell Exhaustion by Integrative Single-Cell RNAseq and Mass Cytometry Analyses

Thursday, May 07 | 8:30AM - 12:00PM
Single Cell Analysis in Tumor Microenvironment
Room: Auditorium

Speaker 9 of 9
Sarah Elisabeth Pierce, Stanford University, USA
Short Talk: Single-Cell Resolution of Chromatin Accessibility in Lung Adenocarcinoma Reveals Genotype-Specific Dependencies

Thursday, May 07 | 12:00PM - 5:00PM
On Own for Lunch


Thursday, May 07 | 12:00PM - 1:00PM
Poster Setup
Room: Passi Perduti


Thursday, May 07 | 1:00PM - 10:00PM
Poster Viewing
Room: Passi Perduti


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