Mitochondria, Metabolism and Heart
joint with Heart Failure: Mechanisms and Therapies
Scientific Organizers: Elizabeth Murphy and Zoltan P. Arany
Date: January 14 - 18, 2021
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Mitochondria are well established as the powerhouse of the cell and are responsible for generating ATP via oxidative metabolism and electron transport. Mitochondrial transporters regulate mitochondrial calcium levels which in turn are important in regulating cell metabolism and death. Alterations in mitochondrial function and metabolism have been shown to be important regulators of cardiovascular disease such as heart failure. Despite the importance of mitochondria in health and disease, the identity of many ion transporters is still unknown. In particular the identity of the mitochondrial permeability pore that regulates cell death is still debated. In addition, the links between mitochondrial dynamics and mitochondrial metabolism and cell death are poorly understood. This meeting will emphasize experts using novel approaches such as high resolution imaging techniques, metabolomics, proteomics and systems biology to elucidate mechanisms by which mitochondrial transporters and mitochondrial dynamics regulate metabolism, death and disease.
Registration opens in January 2020