Scientific Organizers: Patricia Boya, Felix Randow and Masaaki Komatsu
Date: October 04 - 08, 2020
Location: INEC Killarney Convention Centre, Killarney, Co. Kerry, Ireland
Autophagy is an intracellular pathway for degradation that allows for the recycling of cellular components inside lysosomes to sustain tissue homeostasis. Great effort has been devoted to unravel the molecular mechanisms that regulate this pathway but many questions remain still unresolved. In this meeting we have gathered an interdisciplinary group of scientists that will address the current and future challenges on the field. These comprise for example, the existence of non-canonical forms of the pathway and how selectivity is achieved. The meeting will also address the minimal requirements to generate functional autophagosomes and the molecular bases of autophagy regulation. A major focus of the meeting is also to show how model system such as plants, worms and mice help to unravel the physiological roles of this essential pathway and why this research can also be applied to find new therapies for human diseases. In this regard, while it is clear now that many human pathologies have alterations in autophagy how we could manipulate the pathway in vivo is a major challenge of the field that will also be addressed. This meeting will provide thus a unique frame to display the current research and future challenges of the field during physiological and pathological conditions.
Registration opens in January 2020