Immunometabolism at the Crossroads of Obesity and Cancer
joint with Tumor Metabolism
Scientific Organizers: Lydia Lynch and Hongbo Chi
Date: January 16 - 20, 2022
Location: Fairmont Banff Springs, Banff, AB, Canada
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This meeting brings together systemic and cellular immunometabolism for the first time. The field of immunometabolism has generally been split into two largely separate areas- the study of the intrinsic cellular metabolic pathways driving immune response, and the study of leukocytes regulating systemic metabolism. This meeting highlights the interdependence of both arms of immunometabolism, using the settings of obesity and obesity driven cancer as the ideal examples to explore and synergize these areas of research. In addition, linking diet, obesity and immunity is very relevant to the current COVID-19 pandemic, that is disproportionately affecting patients with obesity and type 2 diabetes. Moreover, by holding this meeting jointly with the Keystone meeting on “Tumor Metabolism”, we aim to integrate immunometabolism with cutting edge knowledge and tools in metabolism of cancer cells and the microenvironment to drive the field forward. Anticipated outcomes include the following: 1) New concepts and state of the art technologies that can lead to deeper insights in the field of immunometabolism with the goal of connecting metabolic processes at the organismal, tissue, and cellular levels. 2) Understanding the effects of diet, microbiome and obesity in immune system function and cancer pathogenesis and therapy. 3) Innovative strategies for targeting immunometabolism as therapeutics for cancer, obesity and other disorders, including the approaches of improving immunotherapy and direct targeting of tumor-intrinsic pathways in cancer.
Registration for this meeting is not open yet, it will open later in 2021