Heart Failure: Mechanisms and Therapies
joint with Mitochondria, Metabolism and Heart
Scientific Organizers: David A. Kass and Saptarsi M. Haldar
Date: February 26 - March 01, 2022
Location: Beaver Run Resort, Breckenridge, CO, USA
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The COVID-19 pandemic put the kibosh on our originally planned 2021 HF meeting, as we felt this meeting is really best done in person, we decided to wait a year and try again. The Keystone meetings are being shortened by 25% - 3 days instead of 4, so adjustments to the program have been made. Importantly, even one year later, heart failure (HF) is still a leading global cause of morbidity and mortality. As life expectancy increases, individuals are experiencing the compounded effects of accumulated disease, genetic propensity, environmental stress, and behavior. The underpinnings of HF are multifactorial, providing a broad array of relevant biochemical therapeutic targets that could impact clinical symptoms and outcomes. Aging, the obesity epidemic and associated disorders, such as diabetes, have a major impact on heart failure pathophysiology. The roles of altered metabolism, mitochondrial dysfunction, protein quality control, inflammation, and fibrosis as well as the latest methods for single-cell analysis of subpopulations studies on epigenetic control of disease and heart development/regeneration will be featured. The dawn of a new age in manipulation of heart contractions is upon us and this conference will enable discussion of recent advances in HF treatment, including clinical testing. Many of the speakers are leaders in highly relevant fields that are not always featured at typical HF conferences. One of our goals is to encourage dialog and foster interdisciplinary collaboration between researchers in fields that are all relevant to the failing heart. Lastly, this conference is being paired with another Keystone Symposia conference on Mitochondria, Metabolism and Heart, which will also have a cardiac emphasis. There will be two joint sessions that will focus on mitochondrial function and metabolism, respectively.
Scholarship Deadline: November 16 2021 details
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Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.