Organoids as Tools for Fundamental Discovery and Translation joint with Engineering Multi-Cellular Living Systems Scientific Organizers: Jason R. Spence, Melissa Little and Barbara Treutlein Date: April 03 - 06, 2022 Location: Keystone Resort, Keystone, CO, USA For important information on the coronavirus, please click hereOrganoids are complex three-dimensional in vitro organ-like model systems. Organoids can be derived from pluripotent stem cells or primary donor tissue and have been used to address fundamental questions about development, stem cell biology and organ regeneration. Human organoids have highlighted significant unknowns in human biology and have invigorated new exploration into the cellular makeup of human organs during development, in the adult and during disease. Efforts to improve complexity in organoid systems, and to make organoid systems more robust, reproducible and controlled have prompted efforts to benchmark in vitro organoid systems against their in vivo counterparts, and efforts to control organoid systems through bioengineering approaches. The goals of this symposium are to highlight recent and emerging advances that implement organoids as tools to move several areas of biology forward, including improving complexity and maturation, high content drug screening, disease modeling, and understanding development and evolution. We anticipate that attendees will take away from this meeting new scientific knowledge, new methods and new technical capabilities. Moreover, given that the implementation of organoids in basic discovery and translational research spans a wide range of disciplines, it is likely that this meeting will bring together a diverse audience fostering novel cross-disciplinary interactions. Scholarship Deadline: December 14 2021 details
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Registered attendees of one meeting in a joint pair may participate in sessions of the other, pending space availability.
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