Web Desc
HIV-1 Protection and Control by Vaccination
joint with HIV Pathogenesis: Recent Advances in the Biology and Pathogenesis of Primate Lentiviruses
Organizer(s): M. Juliana McElrath, Gary J. Nabel and Daniel R. Littman
Date: April 05 - 11, 2002
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Wyeth-Lederle Vaccines
Summary of Meeting:
Recent progress in vaccine development offers hope that immunization may slow the HIV-1 epidemic. Insights into immune mechanisms of protection against HIV-1 infection and disease are emerging in clinical and animal studies, which can be applied to immunization strategies. New vaccines designed to elicit these immune responses are rapidly becoming available for implementation in human trials worldwide. Despite these advances, it remains unclear which approach is more likely to be efficacious, and if so, by what mechanism. The overall goal of this symposium is to accelerate understanding of the components necessary to prevent HIV-1 infection by vaccination, and to stimulate the scientific field to participate in moving this effort forward. The most current relevant studies will be integrated with recent advances in HIV pathogenesis and therapeutic interventions. The program will identify barriers to vaccine development, with the intent to foster new avenues of research collaborations that can overcome these hurdles.
Discounted Abstract Deadline: December 13 2001
Discounted Registration Deadline: February 5 2002
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI51327-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Friday, April 05 | 4:00PM - 7:00PM
Registration
Room: Shavano Foyer


Friday, April 05 | 6:15PM - 7:15PM
Welcome
Room: Shavano Foyer/Lobby


Friday, April 05 | 7:15PM - 7:30PM
Orientation
Room: Shavano/Torreys


Friday, April 05 | 7:30PM - 9:30PM
Keynote Address (Joint)
Room: Shavano/Torreys

Speaker 2 of 2
Joseph G. Sodroski, Dana-Farber Cancer Institute, USA
Structure and Function of the HIV-1 Envelope Glycoproteins and Receptors

Friday, April 05 | 7:30PM - 9:30PM
Keynote Address (Joint)
Room: Shavano/Torreys

Speaker 1 of 2
Rafi Ahmed, Emory University School of Medicine, USA
Vaccines and Immune Memory

Saturday, April 06 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Saturday, April 06 | 8:00AM - 11:00AM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 5 of 5
Roger J. Pomerantz, Seres Therapeutics, Inc., USA
Short Talk: Residual HIV-1 Disease Eradication (RHIDE) Using Stimulatory and Novel Intensification Therapy: Dissecting Residual Disease Pathogenesis


Saturday, April 06 | 8:00AM - 11:00AM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 4 of 5
Mark A. Goldsmith, REVOLUTION Medicines, USA
Determinants of Cellular Infection and Depletion by HIV-1


Saturday, April 06 | 8:00AM - 11:00AM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 3 of 5
Didier Trono, Ecole Polytechnique Fédérale de Lausanne, Switzerland
HIV and Chromatin Remodeling Factors


Saturday, April 06 | 8:00AM - 11:00AM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 2 of 5
* David Kabat, Oregon Health & Science University, USA
Innate Resistance of Human Lymphocytes to HIV-1 is Overcome by Vif


Saturday, April 06 | 8:00AM - 11:00AM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 1 of 5
* Bryan R. Cullen, Duke University Medical Center, USA
Role and Mechanism of Action of Tat and Rev


Saturday, April 06 | 8:00AM - 11:00AM
Current Strategies in Clinical Vaccine Trials
Room: Shavano/Torreys

Speaker 4 of 4
Barney S. Graham, NIAID, National Institutes of Health, USA
Phase I Clinical Trials

Saturday, April 06 | 8:00AM - 11:00AM
Current Strategies in Clinical Vaccine Trials
Room: Shavano/Torreys

Speaker 3 of 4
Andrew J. McMichael, Oxford University, UK
DNA and MVA Phase I Trials

Saturday, April 06 | 8:00AM - 11:00AM
Current Strategies in Clinical Vaccine Trials
Room: Shavano/Torreys

Speaker 2 of 4
Emilio A. Emini, Bill and Melinda Gates Foundation, USA
A Potential HIV Vaccine that Elicits Specific and Effective Cellular Immune Responses

Saturday, April 06 | 8:00AM - 11:00AM
Current Strategies in Clinical Vaccine Trials
Room: Shavano/Torreys

Speaker 1 of 4
* M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA
Induction of HIV-Specific Immunity in HIV-1 Vaccine Trials (HVTN)

Saturday, April 06 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Foyer/Lobby


Saturday, April 06 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak


Saturday, April 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays Peak


Saturday, April 06 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Foyer/Lobby


Saturday, April 06 | 5:00PM - 7:00PM
Enzymes
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 2 of 3
Stuart F.J. Le Grice, NCI, National Institutes of Health, USA
Programmed Initiation of DNA Synthesis in Lentiviruses


Saturday, April 06 | 5:00PM - 7:00PM
Enzymes
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 3 of 3
Frederic D. Bushman, University of Pennsylvania, USA
Host Factors Affecting the Early Steps of HIV Replication


Saturday, April 06 | 5:00PM - 7:00PM
Enzymes
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 1 of 3
* Daria J. Hazuda, Merck Research Laboratories, USA
Inhibitors of HIV-1 Integrase


Saturday, April 06 | 5:00PM - 7:00PM
Preclinical Vaccine Trials: Promising Leads
Room: Shavano/Torreys

Speaker 4 of 4
Jeffrey D. Lifson, Leidos Biomedical Research, Inc., USA
Early Transient Antiretroviral Treatment of SIV Infection

Saturday, April 06 | 5:00PM - 7:00PM
Preclinical Vaccine Trials: Promising Leads
Room: Shavano/Torreys

Speaker 3 of 4
Jay A. Berzofsky, NCI, National Institutes of Health, USA
The Importance of Mucosal Immunity in Controlling SHIV Infection and Strategies to Enhance Vaccines

Saturday, April 06 | 5:00PM - 7:00PM
Preclinical Vaccine Trials: Promising Leads
Room: Shavano/Torreys

Speaker 2 of 4
Norman L. Letvin, Beth Israel Deaconess Medical Center, USA
Correlates of Immunity in the Macaque Model

Saturday, April 06 | 5:00PM - 7:00PM
Preclinical Vaccine Trials: Promising Leads
Room: Shavano/Torreys

Speaker 1 of 4
* David I. Watkins, University of Miami, USA
T Cell Responses Against SIV

Saturday, April 06 | 7:00PM - 8:00PM
Welcome Mixer
Room: Grays Peak


Saturday, April 06 | 7:00PM - 9:00PM
Cash Bar
Room: Grays Peak


Saturday, April 06 | 8:00PM - 10:00PM
Poster Session 1
Room: Grays Peak


Sunday, April 07 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Sunday, April 07 | 8:00AM - 11:00AM
Virus - Host Interaction (Joint)
Room: Shavano/Torreys

Speaker 1 of 4
Dan R. Littman, HHMI/New York University School of Medicine, USA
HIV Entry: Animal Models and Strategies for Vaccine Development

Sunday, April 07 | 8:00AM - 11:00AM
Virus - Host Interaction (Joint)
Room: Shavano/Torreys

Speaker 2 of 4
* John P. Moore, Weill Medical College of Cornell University, USA
Studies on Disulfide-Stabilized HIV-1 Envelope Glycoproteins

Sunday, April 07 | 8:00AM - 11:00AM
Virus - Host Interaction (Joint)
Room: Shavano/Torreys

Speaker 3 of 4
Robert W. Doms, University of Pennsylvania School of Medicine, USA
HIV Entry and its Inhibition

Sunday, April 07 | 8:00AM - 11:00AM
Virus - Host Interaction (Joint)
Room: Shavano/Torreys

Speaker 4 of 4
James A. Hoxie, University of Pennsylvania, USA
New Insights into gp120-Chemokine Receptor Interactions from CD4-Independent Isolates of HIV-1 and HIV-2

Sunday, April 07 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Foyer/Lobby


Sunday, April 07 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak


Sunday, April 07 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays Peak


Sunday, April 07 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Foyer/Lobby


Sunday, April 07 | 5:00PM - 7:00PM
HIV Structure (Joint)
Room: Shavano/Torreys

Speaker 1 of 3
B. Matija Peterlin, University of California, San Francisco, USA
From Tat to Nef: Fine Tuning HIV Replication and Infectivity

Sunday, April 07 | 5:00PM - 7:00PM
HIV Structure (Joint)
Room: Shavano/Torreys

Speaker 2 of 3
* Wesley I. Sundquist, University of Utah School of Medicine, USA
HIV-1 Budding

Sunday, April 07 | 5:00PM - 7:00PM
HIV Structure (Joint)
Room: Shavano/Torreys

Speaker 3 of 3
Richard T. Wyatt, IAVI Neutralizing Antibody Center, The Scripps Research Institute, USA
HIV-1 Envelope Glycoproteins: Structural Insights and Vaccine Design

Sunday, April 07 | 7:00PM - 8:00PM
Welcome Mixer
Room: Grays Peak


Sunday, April 07 | 7:00PM - 9:00PM
Cash Bar
Room: Grays Peak


Sunday, April 07 | 8:00PM - 10:00PM
Poster Session 2
Room: Grays Peak


Monday, April 08 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Monday, April 08 | 8:00AM - 11:00AM
Viral Pathogenesis (Joint)
Room: Shavano/Torreys

Speaker 1 of 4
Robert F. Siliciano, Johns Hopkins University School of Medicine, USA
Latency and Viral Evolution in HIV-1 Infection

Monday, April 08 | 8:00AM - 11:00AM
Viral Pathogenesis (Joint)
Room: Shavano/Torreys

Speaker 2 of 4
* Ashley T. Haase, University of Minnesota, USA
The Fast Phase of Slow Lentiviral Infection


Monday, April 08 | 8:00AM - 11:00AM
Viral Pathogenesis (Joint)
Room: Shavano/Torreys

Speaker 3 of 4
James I. Mullins, University of Washington, USA
Selective Pressure and Progression of HIV Infection

Monday, April 08 | 8:00AM - 11:00AM
Viral Pathogenesis (Joint)
Room: Shavano/Torreys

Speaker 4 of 4
Douglas D. Richman, University of California, San Diego, USA
HIV Pathogenesis: Twenty Years of Successes and Failures

Monday, April 08 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Foyer/Lobby


Monday, April 08 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak


Monday, April 08 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays Peak


Monday, April 08 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Foyer/Lobby


Monday, April 08 | 5:00PM - 7:00PM
Immune Reconstitution and Therapeutic Vaccination (Joint)
Room: Shavano/Torreys

Speaker 1 of 3
* Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA
Harnessing the Immune System in the Fight Against AIDS

Monday, April 08 | 5:00PM - 7:00PM
Immune Reconstitution and Therapeutic Vaccination (Joint)
Room: Shavano/Torreys

Speaker 2 of 3
Joseph (Mike) McCune, Bill & Melinda Gates Foundation, USA
HIV-induced perturbations of CD8+ T cell maturation


Monday, April 08 | 5:00PM - 7:00PM
Immune Reconstitution and Therapeutic Vaccination (Joint)
Room: Shavano/Torreys

Speaker 3 of 3
Brigitte Autran, Hôpital Pitié-Salpétrière, UPMC, France
Restoration of HIV-Specific Immunity with Immune-Based Therapeutic Strategies

Monday, April 08 | 7:00PM - 8:00PM
Welcome Mixer
Room: Grays Peak


Monday, April 08 | 7:00PM - 9:00PM
Cash Bar
Room: Grays Peak


Monday, April 08 | 8:00PM - 10:00PM
Poster Session 3
Room: Grays Peak


Tuesday, April 09 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Tuesday, April 09 | 8:00AM - 11:00AM
Optimizing Antigenic Presentation and Effector Responses
Room: Shavano/Torreys

Speaker 1 of 3
* Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA
Dendritic Cells: Antigen Presenting Functions and Applications to Vaccines

Tuesday, April 09 | 8:00AM - 11:00AM
Optimizing Antigenic Presentation and Effector Responses
Room: Shavano/Torreys

Speaker 2 of 3
James P. Allison, University of Texas MD Anderson Cancer Center, USA
More is Less: New Insights into the Mechanisms of Negative
Costimulation by CTLA-4 and its Manipulation in the Enhancement of T Cell Responses


Tuesday, April 09 | 8:00AM - 11:00AM
Optimizing Antigenic Presentation and Effector Responses
Room: Shavano/Torreys

Speaker 3 of 3
Thomas Spies, Fred Hutchinson Cancer Research Center, USA
T Cell Costimulation by NKG2D


Tuesday, April 09 | 8:00AM - 11:00AM
Accessory Functions
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 1 of 6
* Warner Craig Greene, Gladstone Institute of Virology and Immunology, USA
HIV Infection Results in G2 Cell Cycle Arrest in vivo


Tuesday, April 09 | 8:00AM - 11:00AM
Accessory Functions
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 2 of 6
Mario Stevenson, University of Miami, Leonard M. Miller School of Medicine, USA
Mimicry of CD40 by HIV-1 Nef


Tuesday, April 09 | 8:00AM - 11:00AM
Accessory Functions
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 3 of 6
Nathaniel R. Landau, New York University School of Medicine, USA
Blocks to HIV Replication in Non-Human Cells


Tuesday, April 09 | 8:00AM - 11:00AM
Accessory Functions
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 4 of 6
Jon W. Marsh, National Institutes of Health, USA
Nef Actvity in T Cells


Tuesday, April 09 | 8:00AM - 11:00AM
Accessory Functions
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 5 of 6
Andreas Stephan Baur, Germany
Short Talk: The HIV NEF N-Terminus Activates LCK Involving A PcG-Complex Protein


Tuesday, April 09 | 8:00AM - 11:00AM
Accessory Functions
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 6 of 6
Jacek Skowronski, Case Western University, USA
Short Talk: Host Factors that Mediate Nef Function.


Tuesday, April 09 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Foyer/Lobby


Tuesday, April 09 | 11:00AM - 1:00PM
Poster Setup
Room: Grays Peak


Tuesday, April 09 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays Peak


Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 1 of 9
* Deborah L. Birx, Centers for Disease Control and Prevention, USA

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 2 of 9
* Mark B. Feinberg, IAVI International AIDS Vaccine Initiative, USA

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 3 of 9
Jason E. Hammonds, Emory University, USA
Enhanced Stability of Primary Isolate gp120 on Pseudovirions

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 4 of 9
Erica Ollmann Saphire, La Jolla Institute for Immunology, USA
Crystal Structures of a Broadly Neutralizing Antibody: Two Templates for HIV-1 Vaccine Design

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 5 of 9
John R. Mascola, NIAID, National Institutes of Health, USA
Evaluating the Neutralizing Antibody Response Elicited by DNA and Recombinant Adenoviral Vaccines

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 6 of 9
Francisco Veas, Institut de Recherche pour le Development, France
Serial Analysis Genome Expression Method to Study Transcriptomes from Primary Human T Cells Activated by HIV Envelope or Chemokines

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 7 of 9
Michael E. Horn, ProdiGene, USA
Expression of an SIV Protein in Transgenic Maize for Use as an Edible Vaccine and Reagent Supply

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 8 of 9
Luzheng Liu, Brigham and Women's Hospital, USA
Antigen Presentation by Dendritic Cells Following MVA Vaccination

Tuesday, April 09 | 2:30PM - 4:30PM
Workshop 1: Vaccine Innovation and New Investigators
Room: Shavano/Torreys

Speaker 9 of 9
Phillip W. Berman, University of California, Santa Cruz, USA
Update on Phase III Vaccine Trials in the US and Thailand

Tuesday, April 09 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Foyer/Lobby


Tuesday, April 09 | 5:00PM - 7:00PM
New Vaccine Strategies
Room: Shavano/Torreys

Speaker 1 of 4
* Gary J. Nabel, Sanofi, USA
Progress in the Development of Improved AIDS Vaccines

Tuesday, April 09 | 5:00PM - 7:00PM
New Vaccine Strategies
Room: Shavano/Torreys

Speaker 2 of 4
David D. Ho, Aaron Diamond AIDS Research Center (ADARC), Columbia University Medical Center, USA
Clade C Vaccine Approaches

Tuesday, April 09 | 5:00PM - 7:00PM
New Vaccine Strategies
Room: Shavano/Torreys

Speaker 3 of 4
Philip R. Johnson, Children's Hospital of Philadelphia, USA
AAV Vectors as HIV Vaccines

Tuesday, April 09 | 5:00PM - 7:00PM
New Vaccine Strategies
Room: Shavano/Torreys

Speaker 4 of 4
Marta L. Marthas, California National Primate Research Center, USA
Vaccination of Infant Macaques Against Oral Challenge with Pathogenic SIVmac251

Tuesday, April 09 | 5:00PM - 7:00PM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 1 of 4
Michael H. Malim, King's College London, UK
Modulation of HIV-1 Infection Through VIF-Host Cell Interactions


Tuesday, April 09 | 5:00PM - 7:00PM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 2 of 4
C. Martin Stoltzfus, University of Iowa, USA
Repression of HIV-1 RNA Splicing by Exonic Splicing Silencers


Tuesday, April 09 | 5:00PM - 7:00PM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 3 of 4
Heinrich Göttlinger, Dana Farber Cancer Institute, USA
Host Factors in HIV-1 Particle Release


Tuesday, April 09 | 5:00PM - 7:00PM
HIV Life Cycle
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 4 of 4
Paul D. Bieniasz, Rockefeller University, USA
Short Talk: Recruitment of Tsg101 to Sites of Particle Assembly, Mediated by Short Peptide Motifs, is Required for Efficient HIV-1 and Ebola Virus Particle Budding


Tuesday, April 09 | 7:00PM - 8:00PM
Welcome Mixer
Room: Grays Peak


Tuesday, April 09 | 7:00PM - 9:00PM
Cash Bar
Room: Grays Peak


Tuesday, April 09 | 8:00PM - 10:00PM
Poster Session 4
Room: Grays Peak


Wednesday, April 10 | 7:00AM - 8:00AM
Breakfast
Room: Longs/Quandary


Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 1 of 10
* Richard A. Koup, NIAID, National Institutes of Health, USA
HIV and T Cell Help

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 2 of 10
Teunis B.H. Geijtenbeek, University of Amsterdam, Netherlands
Short Talk: Indetification of Different Binding Sites in DC-SIGN for ICAM-3 AND HIV-1

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 3 of 10
Marcus Altfeld, Heinrich-Pette-Institute, Germany
Short Talk: Enhancement of HIV-1-Specific CD8+ T Cell Responses During STI is Largely Due to the Expansion of CD8+ T Cell Responses Pre-Existing in Lymphoid Tissue

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 4 of 10
Daniel C. Douek, NIAID, National Institutes of Health, USA
Short Talk: A Novel Approach to the Analysis of Specificity, Clonality and Frequency of HIV-Specific T Cell Responses Reveals a Mechanism for Control of Viral Escape

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 5 of 10
Jianhong Cao, Fred Hutchinson Cancer Research Center, USA
Short Talk: Escape of HIV-1 Tat Specific CTL Response During Acute Infection

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 6 of 10
Michael Egan, Profectus Biosciences, USA
Short Talk: Immunogenicity and Protective Capacity of VSV-Based Vaccine Vectors Expressing Hiv-1 env and Siv gag in Rhesus Macaques

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 7 of 10
Rama Rao Amara, Emory University, USA
Short Talk: MVA Compared to a DNA/MVA-Vaccine; Slower but Similar Long-Term Control of a SHIV 89.6P Challenge

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 8 of 10
Todd M. Allen, Ragon Institute of MGH, MIT and Harvard, USA
Short Talk: Acute Phase CTL Escape in SIV and HIV

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 9 of 10
Bartek T. Zuber, Swedish Orphan Biovitrum, SOBI, Sweden
Short Talk: CCR5 Gene Immunization Lowers Viral Setpoint and May Select for SIV that Uses CCR5 More Efficiently

Wednesday, April 10 | 8:00AM - 11:00AM
Late Breaking Topics
Room: Shavano/Torreys

Speaker 10 of 10
Douglas F. Nixon, Weill Cornell Medicine, USA
Short Talk: Competitive Selection Pressures From Drug and Immune Responses on HIV RT and Protease Genes

Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 1 of 10
David Camerini, University of California, Irvine, USA
HIV-1 Mediated Signal Transduction via CCR5 Allows Infection of Resting Memory T Cells


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 2 of 10
Jean-Marc Jacque, University of Massachusetts Medical School, USA
Modulating the HIV-1 Replication Cycle through RNAi


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 3 of 10
Melissa J. Robbiani (Pope), Population Council, USA
Nef-Expressing Immature Dendritic Cells Secrete Inflammatory Cytokines and Chemokines, Activate Autologous CD4+ T Cells, and Rescue SIV Delta Nef Replication


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 4 of 10
Michael P. Sherman, J. David Gladstone Institutes, USA
HIV-1 Vpr Nuclear Export is Required for Efficient Macrophage Infection in Lymphoid Tissue


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 5 of 10
Christopher Aiken, Vanderbilt University School of Medicine, USA
Role of Virion Capsid Stability in HIV-1 Infection


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 6 of 10
Olivier Schwartz, Institut Pasteur, France
HIV-1 Nef-Induced Up-Regulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 7 of 10
Laura A. Napolitano, Gladstone Institute of Virology and Immunology, USA
Increased Thymic Mass and Circulating Naive CD4+ T Cell Counts in HIV-1-Infected Adults Treated with Growth Hormone


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 8 of 10
Juan Lama, RetroVirox Inc., USA
Cell-Surface CD4 Modulates HIV Infectivity in T-Cells


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 9 of 10
Ann-Marie M. Roy, University of California, San Francisco, USA
Impact of Co-Receptor Use on HIV-1 'Burst Size' in Dispersed Human Lymphoid Tissue


Wednesday, April 10 | 8:00AM - 11:00AM
Special Topics/Late Breaker
This session is from HIV Pathogenesis
Room: Red Cloud

Speaker 10 of 10
David McDonald, National Institute of Allergy and Infectious Disease, USA
HIV Trafficking in Dendritic Cells


Wednesday, April 10 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Foyer/Lobby


Wednesday, April 10 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Foyer/Lobby


Wednesday, April 10 | 5:00PM - 7:00PM
Viral Evolution (Joint)
Room: Shavano/Torreys

Speaker 1 of 3
Martine Peeters, University of Montpellier, France
Ongoing Exposure of Humans to an Extraordinary Variety of Simian Immunodeficiency Viruses in West Central Africa: Identification of New SIV Lineages

Wednesday, April 10 | 5:00PM - 7:00PM
Viral Evolution (Joint)
Room: Shavano/Torreys

Speaker 2 of 3
* Beatrice H. Hahn, University of Pennsylvania, USA
SIVcpz Infection in Wild Chimpanzees

Wednesday, April 10 | 5:00PM - 7:00PM
Viral Evolution (Joint)
Room: Shavano/Torreys

Speaker 3 of 3
Bette Tina Marie Korber, Los Alamos National Laboratory, USA
Implications of HIV Evolutionary Patterns for Vaccine Strain Selection


Wednesday, April 10 | 7:00PM - 8:00PM
Welcome Mixer
Room: Longs/Quandary


Wednesday, April 10 | 8:00PM - 11:00PM
Entertainment
Room: Longs/Quandary


Wednesday, April 10 | 8:00PM - 11:00PM
Cash Bar
Room: Longs/Quandary


Thursday, April 11 | 10:26AM - 10:26AM
Departure


*Session Chair.