Chromatin: Organizing the Genome for Patterns of Gene Expression in Health and Disease

Organizer(s): Stephen B. Baylin, Susan M. Gasser and Tony Kouzarides

Sponsored in part by The Director's Sponsor Fund

Summary of Meeting:

Exciting recent advances in biology stem from our growing appreciation of how chromatin dynamically modulates the genome to program the repertoire of gene expression. To accomplish this process, which is fundamental to embryonic development and mature cell renewal and differentiation, chromatin assembly must be intimately coordinated with cell cycle control, timing of DNA replication, positioning of genes within nuclear domains, and signal transduction events guiding essential post-translational modifications of the proteins involved. Failure of any step can contribute to diseases ranging from inherited disorders to cancer. Despite the importance of the above arena, we are just beginning to understand the molecular players and their co-ordination during cell fate decisions. This meeting will bring together a diverse range of experts in developmental biology, gene transcription, chromatin modeling complexes, nuclear structure, cell cycle regulation and DNA replication, and study of these processes in disease states, to discuss the current and future status of this key cell biology arena

Discounted Abstract Deadline: September 16 2002

Discounted Registration Deadline: November 11 2002

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