Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Mycobacteria: Physiology, Metabolism and Pathogenesis - Back to the Basics (2011J4)
Tuberculosis: Immunology, Cell Biology and Novel Vaccination Strategies (2011J3)
Tuberculosis: Biology, Pathology and Therapy (2009B3)
Tuberculosis: From Lab Research to Field Trials (2007C6)
Tuberculosis: Integrating Host and Pathogen Biology (2005D1)

Web Desc
Tuberculosis: Integrating Host and Pathogen Biology Organizer(s): Gilla Kaplan, Clifton E. Barry III and Stewart Cole Date: January 25 - 30, 2003 Location: Sagebrush Inn & Suites, Taos, NM, USA Supported by Keystone Symposia Summary of Meeting: With the completion of the genome sequence for both Mycobacterium tuberculosis and Homo sapiens the complexities of pathogen host interaction are now accessible for study. The aims of this meeting are: to review the latest insights obtained from analysis of the genome sequence of M. tuberculosis; to dissect the cell biology of the interaction between M. tuberculosis and host cells; to understand the physiology of the pathogen and identify novel targets for drug development; to discuss the molecular basis of M. tuberculosis strain differences and the implications for transmission and immunity; to explore mechanisms of pathogenesis; to learn how the host develops protective immunity against the pathogen; and to develop strategies for manipulation of the host response to tuberculosis through vaccine development. The stimulating discussion among epidemiologists, cell biologists, immunologists, microbial geneticists, and biotechnologists will define the direction of research and accelerate the development of new therapies, diagnostics, and vaccines and promote the forging of new collaborative efforts. We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1 R13 AI053720-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Tuberculosis: Integrating Host and Pathogen Biology

Organizer(s): Gilla Kaplan, Clifton E. Barry III and Stewart Cole

Date: January 25 - 30, 2003
Location: Sagebrush Inn & Suites, Taos, NM, USA

Supported by Keystone Symposia

Summary of Meeting:

With the completion of the genome sequence for both Mycobacterium tuberculosis and Homo sapiens the complexities of pathogen host interaction are now accessible for study. The aims of this meeting are: to review the latest insights obtained from analysis of the genome sequence of M. tuberculosis; to dissect the cell biology of the interaction between M. tuberculosis and host cells; to understand the physiology of the pathogen and identify novel targets for drug development; to discuss the molecular basis of M. tuberculosis strain differences and the implications for transmission and immunity; to explore mechanisms of pathogenesis; to learn how the host develops protective immunity against the pathogen; and to develop strategies for manipulation of the host response to tuberculosis through vaccine development. The stimulating discussion among epidemiologists, cell biologists, immunologists, microbial geneticists, and biotechnologists will define the direction of research and accelerate the development of new therapies, diagnostics, and vaccines and promote the forging of new collaborative efforts.

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI053720-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Saturday, January 25 \| 3:00PM - 7:00PM Registration Room: Chamisa Lobby
Saturday, January 25 \| 6:15PM - 7:15PM Welcome Room: Chamisa Lobby
Saturday, January 25 \| 7:15PM - 7:30PM Orientation Room: Chamisa 1
Saturday, January 25 \| 7:30PM - 8:30PM Opening Remarks Room: Chamisa 1 Speaker 1 of 1 Clifton E. Barry III, NIAID, National Institutes of Health, USA Opening Remarks
Sunday, January 26 \| 7:00AM - 8:00AM Breakfast Room: Los Vaqueros
Sunday, January 26 \| 8:00AM - 11:00AM Exploratory Genomics - Prokaryotic (Genomes, Proteomes, Stru ctural Genomics) Room: Chamisa 1 Speaker 1 of 4 * Stewart T. Cole, Institut Pasteur, France Evolutionary and Comparative Genomics of the M. tuberculosis Complex
Sunday, January 26 \| 8:00AM - 11:00AM Exploratory Genomics - Prokaryotic (Genomes, Proteomes, Stru ctural Genomics) Room: Chamisa 1 Speaker 2 of 4 William R. Jacobs, Jr., HHMI/Albert Einstein College of Medicine, USA Unmasking the Intracellular Lifestyles of Mycobacterium tuberculosis
Sunday, January 26 \| 8:00AM - 11:00AM Exploratory Genomics - Prokaryotic (Genomes, Proteomes, Stru ctural Genomics) Room: Chamisa 1 Speaker 3 of 4 John T. Belisle, Colorado State University, USA Proteomics for the Study of Tuberculosis
Sunday, January 26 \| 8:00AM - 11:00AM Exploratory Genomics - Prokaryotic (Genomes, Proteomes, Stru ctural Genomics) Room: Chamisa 1 Speaker 4 of 4 Peter M. Small, Bill & Melinda Gates Foundation, USA Comparing Genomes within the Species M. tuberculosis
Sunday, January 26 \| 9:20AM - 9:40AM Coffee Break Room: Chamisa 2
Sunday, January 26 \| 11:00AM - 1:00PM Poster Setup Room: Chamisa 2
Sunday, January 26 \| 1:00PM - 10:00PM Poster Viewing Room: Chamisa 2
Sunday, January 26 \| 4:30PM - 5:00PM Coffee & Snacks Available Room: Chamisa 2
Sunday, January 26 \| 5:00PM - 7:00PM Mycobacterial Lipids and Lipid Metabolism in TB Pathogenesis Room: Chamisa 1 Speaker 1 of 3 * Clifton E. Barry III, NIAID, National Institutes of Health, USA The Role of Polyketides in MTB Virulence
Sunday, January 26 \| 5:00PM - 7:00PM Mycobacterial Lipids and Lipid Metabolism in TB Pathogenesis Room: Chamisa 1 Speaker 2 of 3 Helen Billman-Jacobe, University of Melbourne, Australia Glycopeptidolipid Biosynthesis in Mycobacteria
Sunday, January 26 \| 5:00PM - 7:00PM Mycobacterial Lipids and Lipid Metabolism in TB Pathogenesis Room: Chamisa 1 Speaker 3 of 3 Gilla Kaplan, University of Cape Town, South Africa The Role of MTB Lipids in Immunity and Virulence of Clinical Isolates
Sunday, January 26 \| 7:00PM - 8:00PM Social Hour Room: Los Vaqueros
Sunday, January 26 \| 8:00PM - 10:00PM Poster Session 1: Bacterial Physiology and Genomics Room: Chamisa 2
Monday, January 27 \| 7:00AM - 8:00AM Breakfast Room: Los Vaqueros
Monday, January 27 \| 8:00AM - 11:00AM Regulation and Genetics. Session Sponsored by The Ellison M edical Foundation. Room: Chamisa 1 Speaker 1 of 4 James C. Sacchettini, Texas A & M University, USA The Structural Genomics Consortium
Monday, January 27 \| 8:00AM - 11:00AM Regulation and Genetics. Session Sponsored by The Ellison M edical Foundation. Room: Chamisa 1 Speaker 2 of 4 Harvey Rubin, University of Pennsylvania School of Medicine, USA Regulatory Enzymes in MTB
Monday, January 27 \| 8:00AM - 11:00AM Regulation and Genetics. Session Sponsored by The Ellison M edical Foundation. Room: Chamisa 1 Speaker 3 of 4 * William R. Bishai, Johns Hopkins School of Medicine and K-RITH, USA Sigma Factors and Regulation of Gene Expression in M. tuberculosis
Monday, January 27 \| 8:00AM - 11:00AM Regulation and Genetics. Session Sponsored by The Ellison M edical Foundation. Room: Chamisa 1 Speaker 4 of 4 Neil G. Stoker, Royal Veterinary College, UK Two-Component Systems
Monday, January 27 \| 9:20AM - 9:40AM Coffee Break Room: Chamisa 2
Monday, January 27 \| 11:00AM - 1:00PM Poster Setup Room: Chamisa 2
Monday, January 27 \| 1:00PM - 10:00PM Poster Viewing Room: Chamisa 2
Monday, January 27 \| 4:30PM - 5:00PM Coffee & Snacks Available Room: Chamisa 2
Monday, January 27 \| 5:00PM - 7:00PM Adaptation of the Host and Pathogen to Coexistance Room: Chamisa 1 Speaker 1 of 3 Maria Laura Gennaro, Public Health Research Institute (PHRI), USA Antigen Specificity of the Host Immune Response and Pathogen Biology
Monday, January 27 \| 5:00PM - 7:00PM Adaptation of the Host and Pathogen to Coexistance Room: Chamisa 1 Speaker 2 of 3 John D. McKinney, Swiss Federal Institute of Technology (EPFL), Switzerland MTB Persistence
Monday, January 27 \| 5:00PM - 7:00PM Adaptation of the Host and Pathogen to Coexistance Room: Chamisa 1 Speaker 3 of 3 * Douglas B. Young, Imperial College London, UK Pathogen Adaptations to the Host Immune Response
Monday, January 27 \| 7:00PM - 8:00PM Social Hour Room: Los Vaqueros
Monday, January 27 \| 8:00PM - 10:00PM Poster Session 2: Pathogenesis and Virulence Room: Chamisa 2
Tuesday, January 28 \| 7:00AM - 8:00AM Breakfast Room: Los Vaqueros
Tuesday, January 28 \| 8:00AM - 11:00AM Macrophage MTB Interaction Room: Chamisa 1 Speaker 1 of 4 * David G. Russell, Cornell University, USA Mycobacterium tuberculosis: The Indigestible Microbe
Tuesday, January 28 \| 8:00AM - 11:00AM Macrophage MTB Interaction Room: Chamisa 1 Speaker 2 of 4 Jean Pieters, University of Basel, Switzerland Evasion of Host Cell Defense Mechanisms by Pathogenic Mycobacteria
Tuesday, January 28 \| 8:00AM - 11:00AM Macrophage MTB Interaction Room: Chamisa 1 Speaker 3 of 4 Carl F. Nathan, Weill Cornell Medical College, USA Targeting Defenses of M. tuberculosis Against Reactive Nitrogen Intermediates (RNI)
Tuesday, January 28 \| 8:00AM - 11:00AM Macrophage MTB Interaction Room: Chamisa 1 Speaker 4 of 4 Alan Aderem, Center for Infectious Disease Research, USA The Role of Toll-Like Receptors in Orchestrating the Innate Immune Response
Tuesday, January 28 \| 9:20AM - 9:40AM Coffee Break Room: Chamisa 2
Tuesday, January 28 \| 11:00AM - 1:00PM Poster Setup Room: Chamisa 2
Tuesday, January 28 \| 1:00PM - 10:00PM Poster Viewing Room: Chamisa 2
Tuesday, January 28 \| 4:30PM - 5:00PM Coffee & Snacks Available Room: Chamisa 2
Tuesday, January 28 \| 5:00PM - 7:00PM Immune Responses and Vaccine Development Room: Chamisa 1 Speaker 1 of 3 Robert A. Seder, NIAID, National Institutes of Health, USA Vaccine Strategies to Induce Sustained Cellular Immune Responses in vivo Against Intracellular Infections
Tuesday, January 28 \| 5:00PM - 7:00PM Immune Responses and Vaccine Development Room: Chamisa 1 Speaker 2 of 3 * Peter L. Andersen, Statens Serum Institut, Denmark Tuberculosis Subunit Vaccines – Recent Progress Based on Proteomics, Genomics and Studies in Animal Models
Tuesday, January 28 \| 5:00PM - 7:00PM Immune Responses and Vaccine Development Room: Chamisa 1 Speaker 3 of 3 M. Joseph Colston, Medical Research Council, UK Dendritic Cells and Their Role in Priming Immune Responses to Mycobacteria
Tuesday, January 28 \| 7:00PM - 8:00PM Social Hour Room: Los Vaqueros
Tuesday, January 28 \| 8:00PM - 10:00PM Poster Session 3: Immunology and Vaccines Room: Chamisa 2
Wednesday, January 29 \| 7:00AM - 8:00AM Breakfast Room: Los Vaqueros
Wednesday, January 29 \| 8:00AM - 11:00AM Host Immune Responses to MTB Infection Room: Chamisa 1 Speaker 1 of 4 Jan A.M. Langermans, Biomedical Primate Research Centre, Netherlands The Immune Response to Tuberculosis: Non-Human Primate Models
Wednesday, January 29 \| 8:00AM - 11:00AM Host Immune Responses to MTB Infection Room: Chamisa 1 Speaker 2 of 4 Warwick J. Britton, Centenary Institute, Australia Regulation of the Granulomatous Response to Mycobacterium tuberculosis
Wednesday, January 29 \| 8:00AM - 11:00AM Host Immune Responses to MTB Infection Room: Chamisa 1 Speaker 3 of 4 Anne E. Goldfeld, Children's Hospital Boston, Harvard Medical School, USA Variations in Host Immune Response to TB Infection
Wednesday, January 29 \| 8:00AM - 11:00AM Host Immune Responses to MTB Infection Room: Chamisa 1 Speaker 4 of 4 * Stefan H. E. Kaufmann, Max Planck Institute for Infection Biology, Berlin, Germany The T Cell Response to Mycobacterium tuberculosis
Wednesday, January 29 \| 9:20AM - 9:40AM Coffee Break Room: Chamisa 2
Wednesday, January 29 \| 11:00AM - 11:30AM Poster Setup
Wednesday, January 29 \| 11:30AM - 12:30PM Lunch Room: Los Vaqueros
Wednesday, January 29 \| 12:30PM - 2:30PM Poster Session 4: Diagnostics, Therapeutics and Vaccines
Wednesday, January 29 \| 3:30PM - 4:00PM Coffee & Snacks Available Room: Chamisa 2
Wednesday, January 29 \| 4:00PM - 6:00PM Exploratory Genomics - Eukaryotic (The Host Genomics, Proteo mics, Genetics) Room: Chamisa 1 Speaker 1 of 3 * Alan Sher, NIAID, National Institutes of Health, USA A Novel Gene Family which Controls Acute Host Resistance to Mycobacteria and Other Intracellular Pathogens
Wednesday, January 29 \| 4:00PM - 6:00PM Exploratory Genomics - Eukaryotic (The Host Genomics, Proteo mics, Genetics) Room: Chamisa 1 Speaker 2 of 3 Jean-Laurent Casanova, Rockefeller University, USA Genetic Dissection of Immunity to Mycobacteria: The Human Model
Wednesday, January 29 \| 4:00PM - 6:00PM Exploratory Genomics - Eukaryotic (The Host Genomics, Proteo mics, Genetics) Room: Chamisa 1 Speaker 3 of 3 Richard A. Young, Whitehead Institute for Biomedical Research, USA Exploring the Host Response to Pathogens Using Microarray Technologies
Wednesday, January 29 \| 7:00PM - 8:00PM Social Hour Room: Chamisa 2
Wednesday, January 29 \| 8:00PM - 11:00PM Entertainment Room: Chamisa 2
Wednesday, January 29 \| 8:00PM - 11:00PM Cash Bar Room: Chamisa 2
Thursday, January 30 \| 10:26AM - 10:26AM Departure *Session Chair.