Web Desc
HIV Vaccine Development: Immunological and Biological Challenges
joint with Twenty Years of HIV Research: From Discovery to Understanding
Organizer(s): Richard A. Koup, David C. Montefiori and Brigitte Autran
Date: March 29 - April 04, 2003
Location: Fairmont Banff Springs, Banff, AB, Canada
Sponsored by Wyeth Vaccines Research
Summary of Meeting:
Our efforts to curtail the worldwide spread of HIV infection are bolstered by the fact that we now have new information on the molecular and immunological basis of HIV infection. An intimate understanding of immunological control of HIV, and mechanisms by which HIV escapes that control, form the basis of developing novel strategies to prevent infection and disease. Many new vaccine products are now being tested in animal and human trials. Unlike other infections that have been prevented by vaccination, HIV specifically infects and destroys a key component of the immune response to intracellular pathogens. In addition, HIV is exquisitely capable of evading neutralizing antibody responses. All attempts to eliminate HIV from infected individuals have failed. The overall goal of this symposium will be to integrate the newest information on the molecular and cellular biology of HIV infection, the immune response to that infection, and the results of clinical trials of vaccine products. The program will identify the advances that have been made, and the challenges that remain, in developing a vaccine against HIV. The interaction between basic and applied scientists will foster accelerated research and development on HIV vaccines.
Discounted Abstract Deadline: December 31 2002
Discounted Registration Deadline: January 29 2003
We gratefully acknowledge additional support for this conference from:
Boehringer Ingelheim (Canada) Ltd.Office of AIDS Research, NIH
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI053895-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Saturday, March 29 | 3:00PM - 7:00PM
Registration
Room: Van Horne Foyer


Saturday, March 29 | 6:15PM - 7:15PM
Welcome
Room: Van Horne Foyer


Saturday, March 29 | 7:15PM - 7:30PM
Orientation
Room: Van Horne Ballroom


Saturday, March 29 | 7:30PM - 9:30PM
Keynote Addresses (Joint)
Room: Van Horne Ballroom

Speaker 1 of 4
* Jay A. Levy, University of California, San Francisco, USA

Saturday, March 29 | 7:30PM - 9:30PM
Keynote Addresses (Joint)
Room: Van Horne Ballroom

Speaker 2 of 4
* Richard A. Koup, NIAID, National Institutes of Health, USA

Saturday, March 29 | 7:30PM - 9:30PM
Keynote Addresses (Joint)
Room: Van Horne Ballroom

Speaker 3 of 4
Daniel Tarantola, University of New South Wales, Australia
HIV/AIDS: Status of the Worldwide Epidemic

Saturday, March 29 | 7:30PM - 9:30PM
Keynote Addresses (Joint)
Room: Van Horne Ballroom

Speaker 4 of 4
Richard B. Gaynor, Neon Therapeutics, USA
Intracellular Events Involved in HIV-1 Replication

Sunday, March 30 | 6:30AM - 8:00AM
Breakfast
Room: New Brunswick (NB)/Riverview/Cascade/Conservatory


Sunday, March 30 | 8:00AM - 11:00AM
Pioneer Lecture - Virology (Joint)
Room: Van Horne Ballroom

Speaker 1 of 1
* Mario Stevenson, University of Miami, Leonard M. Miller School of Medicine, USA

Sunday, March 30 | 8:00AM - 11:00AM
Viral Diversity I (Joint)
Room: Van Horne Ballroom

Speaker 1 of 4
Robert W. Doms, University of Pennsylvania School of Medicine, USA
Virus Interaction at the Cell Surface

Sunday, March 30 | 8:00AM - 11:00AM
Viral Diversity I (Joint)
Room: Van Horne Ballroom

Speaker 2 of 4
James E.K. Hildreth, UC Davis College of Biological Sciences, USA
HIV-1, Lipid Rafts, and Primary Macrophages: Modeling HIV-1 as a Trojan Exosome

Sunday, March 30 | 8:00AM - 11:00AM
Viral Diversity I (Joint)
Room: Van Horne Ballroom

Speaker 3 of 4
* David I. Watkins, University of Miami, USA
SIV Diversity and Cellular Immune Responses

Sunday, March 30 | 8:00AM - 11:00AM
Viral Diversity I (Joint)
Room: Van Horne Ballroom

Speaker 4 of 4
Cecilia Cheng-Mayer, Aaron Diamond AIDS Research Center (ADARC), USA
Impact of HIV-1 Coreceptor Usage/Tropism on Viral Transmission, Persistence and Pathogenesis

Sunday, March 30 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Sunday, March 30 | 11:00AM - 1:00PM
Poster Setup
Room: Alberta/NB/Riverview/Cascade/Conservatory


Sunday, March 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Alberta/NB/Riverview/Cascade/Conservatory


Sunday, March 30 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Van Horne Foyer


Sunday, March 30 | 5:00PM - 7:00PM
Viral Diversity II (Joint)
Room: Van Horne Ballroom

Speaker 1 of 6
* Preston A. Marx, Tulane National Primate Research Center, USA

Sunday, March 30 | 5:00PM - 7:00PM
Viral Diversity II (Joint)
Room: Van Horne Ballroom

Speaker 2 of 6
* Robert W. Coombs, University of Washington, USA

Sunday, March 30 | 5:00PM - 7:00PM
Viral Diversity II (Joint)
Room: Van Horne Ballroom

Speaker 3 of 6
Bette Tina Marie Korber, Los Alamos National Laboratory, USA
Recombination: Now You See It, Now You Don't

Sunday, March 30 | 5:00PM - 7:00PM
Viral Diversity II (Joint)
Room: Van Horne Ballroom

Speaker 4 of 6
Julie M. Overbaugh, Fred Hutchinson Cancer Research Center, USA
The Role of Hormones and Viral Diversity in HIV-1 Pathogenesis.

Sunday, March 30 | 5:00PM - 7:00PM
Viral Diversity II (Joint)
Room: Van Horne Ballroom

Speaker 5 of 6
Phyllis J. Kanki, Harvard School of Public Health, USA
Pathogenesis of HIV Infections of Africa

Sunday, March 30 | 5:00PM - 7:00PM
Viral Diversity II (Joint)
Room: Van Horne Ballroom

Speaker 6 of 6
Vanessa M. Hirsch, NIAID, National Institutes of Health, USA
Diversity of SIV: Relationship to Pathogenesis and Vaccine Development

Sunday, March 30 | 7:30PM - 8:30PM
Social Hour
Room: Alberta/NB/Riverview/Cascade/Conservatory


Sunday, March 30 | 8:00PM - 10:00PM
Poster Session 1: CD8 T Cell Immune Responses
Room: Alberta/NB/Riverview/Cascade/Conservatory


Monday, March 31 | 6:30AM - 8:00AM
Breakfast
Room: New Brunswick/Riverview/Cascade/Conservatory


Monday, March 31 | 8:00AM - 11:00AM
Pioneer Lecture - Epidemiology
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 3
* Jan Andersson, Karolinska Institutet, Sweden


Monday, March 31 | 8:00AM - 11:00AM
Pioneer Lecture - Epidemiology
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 3
* Richard W. Price, University of California, San Francisco, USA


Monday, March 31 | 8:00AM - 11:00AM
Pioneer Lecture - Epidemiology
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 3
Harold W. Jaffe, Centers for Disease Control and Prevention, USA
HIV Epidemiology: Then and Now


Monday, March 31 | 8:00AM - 11:00AM
New Findings From Human Clinical Trials
Room: Van Horne Ballroom A-B

Speaker 1 of 5
Emilio A. Emini, Bill and Melinda Gates Foundation, USA
Ongoing Development and Evaluation of a Potential HIV-1 Vaccine Using a Replication-Defective Adenoviral Vector

Monday, March 31 | 8:00AM - 11:00AM
New Findings From Human Clinical Trials
Room: Van Horne Ballroom A-B

Speaker 2 of 5
* Andrew J. McMichael, Oxford University, UK
On the AIDS Vaccine Trail

Monday, March 31 | 8:00AM - 11:00AM
New Findings From Human Clinical Trials
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Barney S. Graham, NIAID, National Institutes of Health, USA
Update on Vaccine Research Center Clinical Trials of Candidate HIV Vaccines

Monday, March 31 | 8:00AM - 11:00AM
New Findings From Human Clinical Trials
Room: Van Horne Ballroom A-B

Speaker 4 of 5
M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA
Induction of Vaccine-Induced T Cell Responses and Their Role in HIV-1 Protection

Monday, March 31 | 8:00AM - 11:00AM
New Findings From Human Clinical Trials
Room: Van Horne Ballroom A-B

Speaker 5 of 5
Phillip W. Berman, University of California, Santa Cruz, USA
Preliminary Results of the Phase III Efficacy Trial of AIDSVAX B/B

Monday, March 31 | 8:00AM - 11:00AM
HIV Pathogenesis I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 4
Gene M. Shearer, National Cancer Institute, National Institutes of Health, USA
HIV-1 Pathogenesis: Revisiting Discarded and Ignored Models


Monday, March 31 | 8:00AM - 11:00AM
HIV Pathogenesis I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 4
Clayton A. Wiley, University of Pittsburgh, USA
HIV and the Brain: What Have We Learned and Where Are We Going?


Monday, March 31 | 8:00AM - 11:00AM
HIV Pathogenesis I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 4
Donald P. Kotler, St. Luke's Roosevelt Hospital Center, USA
HIV Pathogenesis in the Gastrointestinal Tract


Monday, March 31 | 8:00AM - 11:00AM
HIV Pathogenesis I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 4
Paul Klotman, Mount Sinai Medical Center, USA
Renal Epithelium is a Reservoir for HIV-1 Replication


Monday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Monday, March 31 | 11:00AM - 1:00PM
Poster Setup
Room: Alberta/NB/Riverview/Cascade/Conservatory


Monday, March 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Alberta/NB/Riverview/Cascade/Conservatory


Monday, March 31 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Van Horne Foyer


Monday, March 31 | 5:00PM - 7:00PM
Pre-Clinical Leads in Non-Human Primates
Room: Van Horne Ballroom A-B

Speaker 1 of 4
Norman L. Letvin, Beth Israel Deaconess Medical Center, USA
Defining Protective Immunity to SHIV in Non-Human Primates

Monday, March 31 | 5:00PM - 7:00PM
Pre-Clinical Leads in Non-Human Primates
Room: Van Horne Ballroom A-B

Speaker 2 of 4
Ronald C. Desrosiers, University of Miami Miller School of Medicine, USA
Single Cycle SIV as a Vaccine Approach for AIDS Factors that Influence Resistance to Antibody-Mediated Neutralization

Monday, March 31 | 5:00PM - 7:00PM
Pre-Clinical Leads in Non-Human Primates
Room: Van Horne Ballroom A-B

Speaker 3 of 4
* Harriet L. Robinson, GeoVax Inc., USA
A Multiprotein DNA/MVA Vaccine for AIDS

Monday, March 31 | 5:00PM - 7:00PM
Pre-Clinical Leads in Non-Human Primates
Room: Van Horne Ballroom A-B

Speaker 4 of 4
John K. Rose, Yale University School of Medicine, USA
A Single VSV/SHIV Immunization Followed by One Heterologous MVA/SHIV Boost Results in Effective Control of Peak Virus Load After SHIV Challenge

Monday, March 31 | 5:00PM - 7:00PM
HIV Pathogenesis II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 6
* Anthony L. Cunningham, Westmead Institute for Medical Research, Australia


Monday, March 31 | 5:00PM - 7:00PM
HIV Pathogenesis II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 6
* Susan F. Plaeger, NIAID, National Institutes of Health, HHS, USA


Monday, March 31 | 5:00PM - 7:00PM
HIV Pathogenesis II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 6
Henry Masur, National Institutes of Health, USA
Opportunistic Infections in the Era of HAART


Monday, March 31 | 5:00PM - 7:00PM
HIV Pathogenesis II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 6
Patrick S. Moore, University of Pittsburgh Cancer Institute, USA
KSHV and Its Designer Genes


Monday, March 31 | 5:00PM - 7:00PM
HIV Pathogenesis II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 5 of 6
Joel M. Palefsky, University of California, San Francisco, USA
Cofactors: HPV infection


Monday, March 31 | 5:00PM - 7:00PM
HIV Pathogenesis II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 6 of 6
W. Henry Boom, Case Western Reserve University, USA
M. tuberculosis: Hiding from the Host Implications for HIV-TB


Monday, March 31 | 7:30PM - 8:30PM
Social Hour
Room: Alberta/NB/Riverview/Cascade/Conservatory


Monday, March 31 | 8:00PM - 10:00PM
Poster Session 2: The Virus, Antigen Presenting Cells, Innat
e and CD4+ T Cell Responses
Room: Alberta/NB/Riverview/Cascade/Conservatory


Tuesday, April 01 | 6:30AM - 8:00AM
Breakfast
Room: New Brunswick/Riverview/Cascade/Conservatory


Tuesday, April 01 | 8:00AM - 11:00AM
Pioneer Lecture - Immunology (Joint)
Room: Van Horne Ballroom

Speaker 1 of 2
* † Jack H. Nunberg, University of Montana, USA

Tuesday, April 01 | 8:00AM - 11:00AM
Pioneer Lecture - Immunology (Joint)
Room: Van Horne Ballroom

Speaker 2 of 2
Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA
Two Decades of Debate: The Role of Antibodies in HIV Immunity

Tuesday, April 01 | 8:00AM - 11:00AM
Immune Responses in HIV Infection (Joint)
Room: Van Horne Ballroom

Speaker 1 of 4
* David C. Montefiori, Duke University Medical Center, USA
Understanding the New Generation of Neutralizing Antibody Assays

Tuesday, April 01 | 8:00AM - 11:00AM
Immune Responses in HIV Infection (Joint)
Room: Van Horne Ballroom

Speaker 2 of 4
John R. Mascola, NIAID, National Institutes of Health, USA
Neutralizing Antibodies and Protective Immunity

Tuesday, April 01 | 8:00AM - 11:00AM
Immune Responses in HIV Infection (Joint)
Room: Van Horne Ballroom

Speaker 3 of 4
Douglas F. Nixon, Weill Cornell Medicine, USA
CD8 T cell Effector Subsets and HIV infection

Tuesday, April 01 | 8:00AM - 11:00AM
Immune Responses in HIV Infection (Joint)
Room: Van Horne Ballroom

Speaker 4 of 4
Mary Carrington, NCI, National Institutes of Health, USA
The Multifaceted Effects of the HLA class I Loci on HIV-1 Disease

Tuesday, April 01 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Tuesday, April 01 | 11:00AM - 1:00PM
Poster Setup
Room: Alberta/NB/Riverview/Cascade/Conservatory


Tuesday, April 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Alberta/NB/Riverview/Cascade/Conservatory


Tuesday, April 01 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Van Horne Foyer


Tuesday, April 01 | 5:00PM - 7:00PM
The Envelope and Entry
Room: Van Horne Ballroom A-B

Speaker 1 of 4
* Dan R. Littman, HHMI/New York University School of Medicine, USA
Role of Dendritic Cells in HIV Entry and Host Immune Responses

Tuesday, April 01 | 5:00PM - 7:00PM
The Envelope and Entry
Room: Van Horne Ballroom A-B

Speaker 2 of 4
Dennis R. Burton, The Scripps Research Institute, USA
The Recognition of HIV-1 by Broadly Neutralizing Antibodies: Clues for Vaccine Design

Tuesday, April 01 | 5:00PM - 7:00PM
The Envelope and Entry
Room: Van Horne Ballroom A-B

Speaker 3 of 4
Peter D. Kwong, NIAID, National Institutes of Health, USA
Application of Structural Biology to the Development of an HIV Vaccine

Tuesday, April 01 | 5:00PM - 7:00PM
The Envelope and Entry
Room: Van Horne Ballroom A-B

Speaker 4 of 4
Cynthia A. Derdeyn, Emory University, USA
Short Talk: Selective Heterosexual Transmission of Envelope-constrained, Neutralization-sensitive HIV-1

Tuesday, April 01 | 5:00PM - 7:00PM
Immune Responses (Innate) in HIV Infection II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 6
* Mario Clerici, Dipartimento di Fisiologia Medico-Chirurgica e dei Trapianti, Italy


Tuesday, April 01 | 5:00PM - 7:00PM
Immune Responses (Innate) in HIV Infection II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 6
* Carl W. Dieffenbach, NIAID, National Institutes of Health, USA


Tuesday, April 01 | 5:00PM - 7:00PM
Immune Responses (Innate) in HIV Infection II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 6
Bruce A. Beutler, University of Texas Southwestern Medical Center, USA
Forward Genetic Analysis of Innate Immunity


Tuesday, April 01 | 5:00PM - 7:00PM
Immune Responses (Innate) in HIV Infection II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 6
Christine A. Biron, Brown University, USA
Interferon and NK Cell Responses to Viral Infections


Tuesday, April 01 | 5:00PM - 7:00PM
Immune Responses (Innate) in HIV Infection II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 5 of 6
Jay A. Levy, University of California, San Francisco, USA
Innate Immunity: Plasmacytoid Dendritic Cells and the CD8+ Cell Noncytotoxic Anti-HIV Response


Tuesday, April 01 | 5:00PM - 7:00PM
Immune Responses (Innate) in HIV Infection II
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 6 of 6
Deborah J. Anderson, Brigham and Women's Hospital, USA
Genital Tract Mucosal Immunity and HIV Infection


Tuesday, April 01 | 7:30PM - 8:30PM
Social Hour
Room: Alberta/NB/Riverview/Cascade/Conservatory


Tuesday, April 01 | 8:00PM - 10:00PM
Poster Session 3: Pre-Clinical/Clinical Evaluation of Vaccin
e Strategies
Room: Alberta/NB/Riverview/Cascade/Conservatory


Wednesday, April 02 | 6:30AM - 8:00AM
Breakfast
Room: New Brunswick/Riverview/Cascade/Conservatory


Wednesday, April 02 | 8:00AM - 11:00AM
Pioneer Lecture - Clinical Approaches
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 3
* Salvatore T. Butera, Centers for Disease Control and Prevention, USA


Wednesday, April 02 | 8:00AM - 11:00AM
Pioneer Lecture - Clinical Approaches
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 3
* Barbara Weiser, New York State Department of Health, USA


Wednesday, April 02 | 8:00AM - 11:00AM
Pioneer Lecture - Clinical Approaches
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 3
Paul A. Volberding, University of California, San Francisco, USA
Clinical Care


Wednesday, April 02 | 8:00AM - 11:00AM
Immunopathogenesis I
Room: Van Horne Ballroom A-B

Speaker 1 of 5
* Rafi Ahmed, Emory University School of Medicine, USA
Understanding Immunological Memory to Improve Vaccination Strategies'

Wednesday, April 02 | 8:00AM - 11:00AM
Immunopathogenesis I
Room: Van Horne Ballroom A-B

Speaker 2 of 5
Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA
Immune Control and Immune Failure in HIV Infection

Wednesday, April 02 | 8:00AM - 11:00AM
Immunopathogenesis I
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Giuseppe Pantaleo, Centre Hospitalier Universitaire Vaudois, Switzerland
Protective CD4 and CD8 T Cell Responses in HIV-1 Infection

Wednesday, April 02 | 8:00AM - 11:00AM
Immunopathogenesis I
Room: Van Horne Ballroom A-B

Speaker 4 of 5
Genoveffa Franchini, NCI, National Institutes of Health, USA
Modeling Immune Intervention Strategies for HIV-1 Infection of Humans in the Macaque Model

Wednesday, April 02 | 8:00AM - 11:00AM
Immunopathogenesis I
Room: Van Horne Ballroom A-B

Speaker 5 of 5
Olivier Schwartz, Institut Pasteur, France
HIV and Dendritic Cells: Virus Spread and Antigen Presentation

Wednesday, April 02 | 8:00AM - 11:00AM
Antiviral Strategies I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 4
Carl Grunfeld, Veterans Affairs Medical Center, USA
The Role of Antiretroviral Drugs in Metabolic and Fat Distribution Changes of HIV Infection


Wednesday, April 02 | 8:00AM - 11:00AM
Antiviral Strategies I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 4
Edward A. Berger, NIAID, National Institutes of Health, USA
Immunotoxins to Target HIV Infected Cell Reservoirs


Wednesday, April 02 | 8:00AM - 11:00AM
Antiviral Strategies I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 4
Flossie Wong-Staal, ItherX Pharmaceuticals Inc., USA
Identification of Essential HIV Cellular Co-Factors through Genomic Approaches


Wednesday, April 02 | 8:00AM - 11:00AM
Antiviral Strategies I
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 4
Michael M. Lederman, Case Western Reserve University, USA
Interleukin-2: A Determinant of Immune Competence in HIV disease? Will Administration Confer Clinical Benefit?


Wednesday, April 02 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Wednesday, April 02 | 11:00AM - 1:00PM
Poster Setup
Room: Alberta/NB/Riverview/Cascade/Conservatory


Wednesday, April 02 | 1:00PM - 10:00PM
Poster Viewing
Room: Alberta/NB/Riverview/Cascade/Conservatory


Wednesday, April 02 | 2:30PM - 4:30PM
Workshop: Recent Developments in Cytokine Augmentation of Va
ccine-Induced Immunity
Room: Van Horne Ballroom A-B

Speaker 1 of 5
* Robert A. Seder, NIAID, National Institutes of Health, USA

Wednesday, April 02 | 2:30PM - 4:30PM
Workshop: Recent Developments in Cytokine Augmentation of Va
ccine-Induced Immunity
Room: Van Horne Ballroom A-B

Speaker 2 of 5
Karl J. Ljungberg, Karolinska Institutet, Sweden
Priming with DNA and Recombinant GM-CSF Followed by Protein CpG-ODN Boost Induces Strong Anti HIV-1 Envelope Immune Responses in Mice

Wednesday, April 02 | 2:30PM - 4:30PM
Workshop: Recent Developments in Cytokine Augmentation of Va
ccine-Induced Immunity
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Dan H. Barouch, Beth Israel Deaconess Medical Center, USA
Chemoattractant Plasmid Cytokines Augment DNA Vaccine-Elicited Immune Responses

Wednesday, April 02 | 2:30PM - 4:30PM
Workshop: Recent Developments in Cytokine Augmentation of Va
ccine-Induced Immunity
Room: Van Horne Ballroom A-B

Speaker 4 of 5
* John H. Eldridge, Auro Vaccines, USA
Immunogenicity and Protective Capacity of a Cytokine-Enhanced DNA Prime/rVSV Boost Vaccination Regimen in Rhesus Macaques

Wednesday, April 02 | 2:30PM - 4:30PM
Workshop: Recent Developments in Cytokine Augmentation of Va
ccine-Induced Immunity
Room: Van Horne Ballroom A-B

Speaker 5 of 5
David B. Weiner, Wistar Institute, USA
Th1 Plasmid Cytokine Enhancement of RNA Optimized Plasmid DNA Vaccine Potency In Non Human Primates Suggests Attainment of a Critical Milestone In DNA Vaccine and Immune Therapy Development

Wednesday, April 02 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Van Horne Foyer


Wednesday, April 02 | 5:00PM - 7:00PM
Immunopathogenesis II
Room: Van Horne Ballroom A-B

Speaker 1 of 4
Robert F. Siliciano, Johns Hopkins University School of Medicine, USA
Halting HIV Evolution

Wednesday, April 02 | 5:00PM - 7:00PM
Immunopathogenesis II
Room: Van Horne Ballroom A-B

Speaker 2 of 4
* Douglas D. Richman, University of California, San Diego, USA
The Evolution and Neutralization Escape of HIV

Wednesday, April 02 | 5:00PM - 7:00PM
Immunopathogenesis II
Room: Van Horne Ballroom A-B

Speaker 3 of 4
Daniel C. Douek, NIAID, National Institutes of Health, USA
In Vivo distribution of HIV among T cell subsets

Wednesday, April 02 | 5:00PM - 7:00PM
Immunopathogenesis II
Room: Van Horne Ballroom A-B

Speaker 4 of 4
Louis J. Picker, Oregon Health & Science University, USA
T Cell Dynamics in SIV Infection

Wednesday, April 02 | 5:00PM - 7:00PM
HIV Pathogenesis III
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 5
* Ronald G. Collman, University of Pennsylvania, USA


Wednesday, April 02 | 5:00PM - 7:00PM
HIV Pathogenesis III
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 5
* Loyda M. Meléndez, University of Puerto Rico School of Medicine, USA


Wednesday, April 02 | 5:00PM - 7:00PM
HIV Pathogenesis III
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 5
Crystal L. Mackall, Stanford University, USA
Therapeutic Modulation of T Cell Homeostasis


Wednesday, April 02 | 5:00PM - 7:00PM
HIV Pathogenesis III
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 5
Maria Prins, Municipal Health Service, Netherlands
Gender Differences in HIV Infection


Wednesday, April 02 | 5:00PM - 7:00PM
HIV Pathogenesis III
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 5 of 5
Keith R. Fowke, University of Manitoba, Canada
Natural Immunity to HIV Infection


Wednesday, April 02 | 7:30PM - 8:30PM
Social Hour
Room: Alberta/NB/Riverview/Cascade/Conservatory


Wednesday, April 02 | 8:00PM - 10:00PM
Poster Session 4: HIV Tropism, Entry and Neutralizing Antibo
dies
Room: Alberta/NB/Riverview/Cascade/Conservatory


Thursday, April 03 | 6:30AM - 8:00AM
Breakfast
Room: NewBrunswick/Riverview/Cascade/Conservatory


Thursday, April 03 | 8:00AM - 11:00AM
Novel Approaches in Pre-Clinical and Clinical Development
Room: Van Horne Ballroom A-B

Speaker 1 of 4
Robert E. Johnston, Global Vaccines, Inc., USA
Use of VEE to Stimulate Protective Immunity to HIV

Thursday, April 03 | 8:00AM - 11:00AM
Novel Approaches in Pre-Clinical and Clinical Development
Room: Van Horne Ballroom A-B

Speaker 2 of 4
* Philip R. Johnson, Children's Hospital of Philadelphia, USA
Pre-clinical Evaluation of a Novel HIV Vaccine Based on an Adeno-associated Virus Vector.

Thursday, April 03 | 8:00AM - 11:00AM
Novel Approaches in Pre-Clinical and Clinical Development
Room: Van Horne Ballroom A-B

Speaker 3 of 4
Jeffrey D. Lifson, Leidos Biomedical Research, Inc., USA
Control of Pathogenic SIV Infection: Different Routes to the Same Goal

Thursday, April 03 | 8:00AM - 11:00AM
Novel Approaches in Pre-Clinical and Clinical Development
Room: Van Horne Ballroom A-B

Speaker 4 of 4
Brigitte Autran, Hôpital Pitié-Salpétrière, UPMC, France
Effect of Therapeutic Vaccination and STI on Immune Control of HIV

Thursday, April 03 | 8:00AM - 11:00AM
HIV Pathogenesis IV
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 6
* Peter Simmonds, University of Edinburgh, UK


Thursday, April 03 | 8:00AM - 11:00AM
HIV Pathogenesis IV
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 6
Klaus Strebel, NIAID, National Institutes of Health, USA
HIV-1 Vif: A Multifunctional Adaptor Molecule


Thursday, April 03 | 8:00AM - 11:00AM
HIV Pathogenesis IV
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 6
Frederic D. Bushman, University of Pennsylvania, USA
Twenty Years of Research on Retroviral Integration


Thursday, April 03 | 8:00AM - 11:00AM
HIV Pathogenesis IV
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 6
Tristram G. Parslow, Emory University, USA
RNA Dimers as Templates for Viral and Cellular Reverse Transcription


Thursday, April 03 | 8:00AM - 11:00AM
HIV Pathogenesis IV
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 5 of 6
* David Camerini, University of California, Irvine, USA


Thursday, April 03 | 8:00AM - 11:00AM
HIV Pathogenesis IV
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 6 of 6
James J. Goedert, National Institutes of Health, USA
Roles of Hepatitis C virus (HCV) and GB virus C (GBV-C) in HIV Pathogenesis


Thursday, April 03 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Thursday, April 03 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Van Horne Foyer


Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 1 of 9
* Richard A. Koup, NIAID, National Institutes of Health, USA

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 2 of 9
Daniel E. Kaufmann, University of Montreal, Canada
Short Talk: Comprehensive Analysis of HIV-Specific CD4 Responses by IFN-Gamma Elispot in Early Chronic HIV-1 Infection Shows Marked Immunodominance of gag and nef and the Presence of Broadly Recognized Peptides

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 3 of 9
Victor Appay, INSERM U1135 - CIMI, France
Short Talk: Activation and Differentiation of HIV Non-Specific CD8+ T Cells During HIV-1 Infection

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 4 of 9
Matthew R. Reynolds, University of Wisconsin-Madison, USA
Short Talk: Viral Dissemination and Kinetics of Cytotoxic T-Lymphocyte Development in Mamu-A*01 Positive Macaques Infected with SIVmac239

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 5 of 9
Ann Chahroudi, Emory University School of Medicine, USA
Short Talk: Towards Better Strategies for Poxvirus-Based HIV Vaccines: Studies of the Cellular Tropism of Modified Vaccinia Ankara (MVA) and Vaccinia Virus (VV) in Primary Human Cells

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 6 of 9
Teunis B.H. Geijtenbeek, University of Amsterdam, Netherlands
Short Talk: Mycobacteria Suppress Dendritic Cell Function: Effects on HIV-1 Infection

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 7 of 9
John P. Moore, Weill Medical College of Cornell University, USA
Short Talk: Prevention of Virus Transmission to Macaque Monkeys by Vaginally Applied Entry Inhibitors

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 8 of 9
Leonidas Stamatatos, Fred Hutchinson Cancer Research Center, USA
Short Talk: Priming by Vaccination of HIV Envelope-Specific B-Cell Responses Allows for the Long-Term Control of SHIVSF162P4-Replication in Macaques

Thursday, April 03 | 5:00PM - 7:00PM
Late Breakers
Room: Van Horne Ballroom A-B

Speaker 9 of 9
Pascal Poignard, IAVI Neutralizing Antibody Center at The Scripps Research Institute, USA
Short Talk: Stoichiometry of Neutralization of the Primary HIV-1 Isolate JR-CSF by the Anti-CD4 Binding Site Antibody b12

Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 1 of 9
* Alan L. Landay, Rush Medical University, USA


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 2 of 9
Jerome A. Zack, University of California, Los Angeles, USA
Strategies to Eliminate Latent HIV


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 3 of 9
David M. Margolis, University of North Carolina at Chapel Hill, USA
Derepression by DNA-binding Polyamides Allows Outgrowth of Human Immunodeficiency Type 1 from Resting CD4+ T Cells: Regulators of HIV Latency


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 4 of 9
Thomas J. Hope, Northwestern University, USA
Enhancement of HIV Infection by Dendritic Cells: Transfer of HIV to Target Cells Through an Infectious Synapse


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 5 of 9
Leonid Margolis, NICHD, National Institutes of Health, USA
Viral Interactions in HIV-Infected Human Lymphoid Tissue


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 6 of 9
Joshua J. Anzinger, NHLBI, National Institutes of Health, USA
Attachment Levels of HIV Differ between PBMC Donors In A CD4 Independent Manner


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 7 of 9
Edward Barker, Rush University Medical Center, USA
Inability of Natural Killer Cells to Destroy Autologous HIV-Infected Primary CD4+ T Cells


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 8 of 9
David J. Volsky, Columbia University, St. Luke's Roosevelt Hospital Center, USA
Interaction of HIV with Astrocytes: A Case for a Direct Role of HIV in Neuropathogenesis


Thursday, April 03 | 5:00PM - 7:00PM
Late Breaking Observations and Conclusions
This session is from HIV Research
Room: Van Horne Ballroom C

Speaker 9 of 9
Lishan Su, University of North Carolina at Chapel Hill, USA
A Novel Genetic Approach to Inactivating Chemokine Receptors by a Modified HIV Protein


Thursday, April 03 | 7:30PM - 8:30PM
Social Hour
Room: Alberta/NB/Riverview/Cascade/Conservatory


Thursday, April 03 | 8:30PM - 11:30PM
Entertainment
Room: Alberta/NB/Riverview/Cascade/Conservatory


Thursday, April 03 | 8:30PM - 11:30PM
Cash Bar
Room: Alberta/NB/Riverview/Cascade/Conservatory


Friday, April 04 | 10:26AM - 10:26AM
Departure


*Session Chair.