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This meeting took place in the past. Here is a list of meetings that are related:
Mouse Models at the Frontiers of Cancer Discovery (2007X4)
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Web Desc
Mouse Models of Human Cancer
Organizer(s): Allan Balmain and Tyler Jacks
Date: February 17 - 22, 2004
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Novartis Pharmaceuticals Corporation
Summary of Meeting:
The main theme of the meeting will be the exploration, using the best mouse models of the major human cancers, of questions related to the target cells for tumor development, the genetic basis to tumor susceptibility, sequential somatic genetic changes during tumor initiation promotion and progression, comparative mouse-human cancer genetics, the role of stromal/accessory cells, the immune response and cancer, and approaches to early detection using imaging or surrogate markers. A major objective will be to emphasize the parallels between mouse models and human cancers, and the advantages of these models to address questions related not only to the basic biology, but also to more practical aspects of gene discovery and therapy. Two of the sessions will be on the functions of stromal/endothelial/immune cells in cancer development to explore non-cell autonomous effects in tumor growth.
Discounted Abstract Deadline: October 16 2003
Discounted Registration Deadline: December 24 2003
We gratefully acknowledge additional support for this conference from:
Cell Signaling Technology, Inc.
Novartis Pharmaceuticals Corporation
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
Program
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Tuesday, February 17
| 3:00PM - 7:00PM
Registration
Room: Shavano Peak Foyer
Tuesday, February 17
| 6:15PM - 7:15PM
Refreshments
Room: Shavano Peak Foyer
Tuesday, February 17
| 7:15PM - 7:30PM
Orientation
Room: Red Cloud
Tuesday, February 17
| 7:30PM - 9:30PM
Keynote Session
Room: Red Cloud
Speaker 1 of 3
* Tyler Jacks
, Massachusetts Institute of Technology, USA
Tuesday, February 17
| 7:30PM - 9:30PM
Keynote Session
Room: Red Cloud
Speaker 2 of 3
J. Michael Bishop
, University of California, San Francisco, USA
Mouse Models Rule
Tuesday, February 17
| 7:30PM - 9:30PM
Keynote Session
Room: Red Cloud
Speaker 3 of 3
Harold E. Varmus
, Weill Cornell Medical College, USA
Making Mouse Models is Not the Same as Using Them: What We Should be Learning
Wednesday, February 18
| 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 1 of 7
Jeffrey E. Green
, National Cancer Institute, National Institutes of Health, USA
Genomic Approaches to Define the Molecular Anatomy of Mouse Mammary Cancer Models and Their Relationship to Human Breast Cancer
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 2 of 7
Donna G. Albertson
, University of California, San Francisco, USA
Genomic Alterations in Mouse and Human Cancers
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 3 of 7
* Ronald A. DePinho
, University of Texas MD Anderson Cancer Center, USA
Modeling Cancer and Cancer Genomes in the Mouse
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 4 of 7
Tyler Jacks
, Massachusetts Institute of Technology, USA
Modeling Lung Cancer in the Mouse
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 5 of 7
E. Alejandro Sweet-Cordero
, Stanford University, USA
Short Talk
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 6 of 7
Alan R. Clarke
, Cardiff University, UK
Short Talk: Investigating the Functional Requirement for Apc through Conditional Deletion in the Mouse
Wednesday, February 18
| 8:00AM - 11:15AM
Comparative Mouse-Human Cancer Genetics
Room: Red Cloud
Speaker 7 of 7
Matthias Hebrok
, University of California, San Francisco, USA
Short Talk: Embryonic Signaling Pathways in Pancreatic Cancer
Wednesday, February 18
| 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer
Wednesday, February 18
| 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys
Wednesday, February 18
| 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys
Wednesday, February 18
| 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Peak Foyer
Wednesday, February 18
| 5:00PM - 7:00PM
Stem Cells and Cancer
Room: Red Cloud
Speaker 1 of 4
*
Elaine V. Fuchs
, Rockefeller University, USA
Stem Cell Lineages of the Skin
Wednesday, February 18
| 5:00PM - 7:00PM
Stem Cells and Cancer
Room: Red Cloud
Speaker 2 of 4
Fiona M. Watt
, King's College London School of Medicine, UK
Contribution of Stem Cells and Differentiated Cells to Tumors of the Epidermis
Wednesday, February 18
| 5:00PM - 7:00PM
Stem Cells and Cancer
Room: Red Cloud
Speaker 3 of 4
Robert J. Coffey, Jr.
, Vanderbilt University Medical Center, USA
New Insights into Progenitor Cells of the GI Tract: Less Clandestine in the Intestine
Wednesday, February 18
| 5:00PM - 7:00PM
Stem Cells and Cancer
Room: Red Cloud
Speaker 4 of 4
William M. Keyes
, Cold Spring Harbor Laboratory, USA
Short Talk: P63 Ablation Activates Key Cellular Processes during Epidermal Morphogenesis
Wednesday, February 18
| 7:00PM - 8:00PM
Social Hour
Room: Shavano/Torreys
Wednesday, February 18
| 7:30PM - 10:00PM
Poster Session 1
Room: Shavano/Torreys
Thursday, February 19
| 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys
Thursday, February 19
| 8:00AM - 11:30AM
Genetic Basis of Cancer Susceptibility
Room: Red Cloud
Speaker 1 of 6
Beverly A. Mock
, NCI, National Institutes of Health, USA
Compound Defects in Cancer Susceptibility Genes Contribute to Plasmacytomagenesis
Thursday, February 19
| 8:00AM - 11:30AM
Genetic Basis of Cancer Susceptibility
Room: Red Cloud
Speaker 2 of 6
Allan Balmain
, University of California, San Francisco, USA
Germline and Somatic Mutations in Mouse Models of Human Cancer
Thursday, February 19
| 8:00AM - 11:30AM
Genetic Basis of Cancer Susceptibility
Room: Red Cloud
Speaker 3 of 6
* William F. Dove
, University of Wisconsin-Madison, USA
From the Apc-Min Mouse Model to Genes and Molecules Involved in Human Colon Cancer
Thursday, February 19
| 8:00AM - 11:30AM
Genetic Basis of Cancer Susceptibility
Room: Red Cloud
Speaker 4 of 6
David W. Threadgill
, University of North Carolina at Chapel Hill, USA
Mouse Strain-Dependent Susceptibility to Colorectal Cancer and Colonization by the Gastrointestinal Flora
Thursday, February 19
| 8:00AM - 11:30AM
Genetic Basis of Cancer Susceptibility
Room: Red Cloud
Speaker 5 of 6
Lynn M. Matrisian
, Vanderbilt University School of Medicine, USA
Mouse Models in Translational Research
Thursday, February 19
| 8:00AM - 11:30AM
Genetic Basis of Cancer Susceptibility
Room: Red Cloud
Speaker 6 of 6
Andrea I. McClatchey
, Massachusetts General Hospital, USA
Short Talk: A Mouse Model of Stem Cell Derived Liver Cancer
Thursday, February 19
| 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer
Thursday, February 19
| 11:30AM - 1:00PM
Poster Setup
Room: Shavano/Torreys
Thursday, February 19
| 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys
Thursday, February 19
| 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Peak Foyer
Thursday, February 19
| 5:00PM - 7:00PM
Tumor Imaging and Early Detection
Room: Red Cloud
Speaker 1 of 6
* Terry A. Van Dyke
, National Cancer Institute, National Institutes of Health, USA
Thursday, February 19
| 5:00PM - 7:00PM
Tumor Imaging and Early Detection
Room: Red Cloud
Speaker 2 of 6
Christopher H. Contag
, Institute for Quantitative Health Sciences and Engineering, USA
Advancing Mouse Models in-vivo Dynamic Imaging Systems
Thursday, February 19
| 5:00PM - 7:00PM
Tumor Imaging and Early Detection
Room: Red Cloud
Speaker 3 of 6
Natasha Grant Deane
, Vanderbilt University Medical Center, USA
Short Talk: The Use of High Field MRI to Detect and Characterize Cancer Progression in Experimental Mouse Livers
Thursday, February 19
| 5:00PM - 7:00PM
Tumor Imaging and Early Detection
Room: Red Cloud
Speaker 4 of 6
Leonard Hofstra
, Maastricht University Hospital, Netherlands
Short Talk: Molecular Imaging of Apoptosis
Thursday, February 19
| 5:00PM - 7:00PM
Tumor Imaging and Early Detection
Room: Red Cloud
Speaker 5 of 6
Byron C. Hann
, University of California, San Francisco, USA
Short Talk: A Murine Model for Rapid and Sensitive in vivo Tumor Detection
Thursday, February 19
| 5:00PM - 7:00PM
Tumor Imaging and Early Detection
Room: Red Cloud
Speaker 6 of 6
William G. Kaelin, Jr.
, Dana-Farber Cancer Institute, USA
Bioluminescent Imaging of Molecular Pathways Relevant to Cancer
Thursday, February 19
| 7:00PM - 8:00PM
Social Hour
Room: Shavano/Torreys
Thursday, February 19
| 7:30PM - 10:00PM
Poster Session 2
Room: Shavano/Torreys
Friday, February 20
| 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys
Friday, February 20
| 8:00AM - 11:30AM
Genetically Engineered Models of Human Cancer. Session Spon
sored in part by GenPath Pharmaceuticals, Inc.
Room: Red Cloud
Speaker 1 of 5
Anton J. M. Berns
, Netherlands Cancer Institute, Netherlands
Utility of Mouse Models for Human Cancer
Friday, February 20
| 8:00AM - 11:30AM
Genetically Engineered Models of Human Cancer. Session Spon
sored in part by GenPath Pharmaceuticals, Inc.
Room: Red Cloud
Speaker 2 of 5
Mariano Barbacid
, Centro Nacional de Investigaciones Oncológicas, Spain
Engineering Mouse Models for Target Validation in Cancer: Cyclin-Dependent Kinases and their Inhibitors
Friday, February 20
| 8:00AM - 11:30AM
Genetically Engineered Models of Human Cancer. Session Spon
sored in part by GenPath Pharmaceuticals, Inc.
Room: Red Cloud
Speaker 3 of 5
Terry A. Van Dyke
, National Cancer Institute, National Institutes of Health, USA
Modeling Cancer Mechanisms in the Mouse
Friday, February 20
| 8:00AM - 11:30AM
Genetically Engineered Models of Human Cancer. Session Spon
sored in part by GenPath Pharmaceuticals, Inc.
Room: Red Cloud
Speaker 4 of 5
*
Guillermina Lozano
, University of Texas MD Anderson Cancer Center, USA
Germline Mutations in the p53/Mdm2 Pathway and Cancer Development
Friday, February 20
| 8:00AM - 11:30AM
Genetically Engineered Models of Human Cancer. Session Spon
sored in part by GenPath Pharmaceuticals, Inc.
Room: Red Cloud
Speaker 5 of 5
Christopher J. Kemp
, Fred Hutchinson Cancer Research Center, USA
The Genetics and Biology of Tumor Suppression by p27/Kip1
Friday, February 20
| 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer
Friday, February 20
| 11:30AM - 1:00PM
Poster Setup
Room: Shavano/Torreys
Friday, February 20
| 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys
Friday, February 20
| 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Peak Foyer
Friday, February 20
| 5:00PM - 7:00PM
Stromal Cells and Tumor Development
Room: Red Cloud
Speaker 1 of 4
* Mary Helen Barcellos-Hoff
, New York School of Medicine, USA
Non-Mutagenic Actions of Radiation Carcinogenesis in Mouse and Human Mammary Models
Friday, February 20
| 5:00PM - 7:00PM
Stromal Cells and Tumor Development
Room: Red Cloud
Speaker 2 of 4
Gerald R. Cunha
, University of California, San Francisco, USA
Stromal Cell Control of Prostate Cancer Progression
Friday, February 20
| 5:00PM - 7:00PM
Stromal Cells and Tumor Development
Room: Red Cloud
Speaker 3 of 4
Erwin F. Wagner
, Spanish National Cancer Research Centre, Spain
The Dual Functions of AP-1 (Fos/Jun) in Cancer Development
Friday, February 20
| 5:00PM - 7:00PM
Stromal Cells and Tumor Development
Room: Red Cloud
Speaker 4 of 4
Mikala Egeblad
, Cold Spring Harbor Laboratory, USA
Short Talk: Real-Time Imaging of Mammary Carcinoma Progression
Friday, February 20
| 7:00PM - 8:00PM
Social Hour
Room: Shavano/Torreys
Friday, February 20
| 7:30PM - 10:00PM
Poster Session 3
Room: Shavano/Torreys
Saturday, February 21
| 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 1 of 7
* Douglas Hanahan
, ISREC, Switzerland
Angiogenesis Inhibitors in Cancer Therapy
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 2 of 7
Johanna A. Joyce
, University of Lausanne, Switzerland
Short Talk
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 3 of 7
Eric Holland
, Memorial Sloan-Kettering Cancer Center, USA
Mouse Models of Glioma Formation and Maintenance
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 4 of 7
Scott W. Lowe
, Memorial Sloan Kettering Cancer Center, USA
Linking Cancer Genetics to Cancer Therapy in Mouse Models
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 5 of 7
Pier Paolo Pandolfi
, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Pokemon: The Birth and Raise of a Cancer Gene
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 6 of 7
Pernilla Roswall
, Uppsala University, Sweden
Short Talk: Tumor Stroma as a Target for Therapy: Effects of TGF-beta Inhibition in Experimental Thyroid Carcinoma
Saturday, February 21
| 8:00AM - 11:00AM
Experimental Therapeutics Using Engineered Mouse Models
Room: Red Cloud
Speaker 7 of 7
Stephen N. Jones
, University of Massachusetts Medical School, USA
Short Talk: Wnt5a Inhibits B Cell Proliferation and Functions as a Tumor Suppressor in Hematopoietic Tissue
Saturday, February 21
| 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer
Saturday, February 21
| 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Shavano Peak Foyer
Saturday, February 21
| 5:00PM - 7:00PM
Analysis of Regulatory Networks in Cancer Biology
Room: Red Cloud
Speaker 1 of 4
* Allan Balmain
, University of California, San Francisco, USA
Saturday, February 21
| 5:00PM - 7:00PM
Analysis of Regulatory Networks in Cancer Biology
Room: Red Cloud
Speaker 2 of 4
Zoltan N. Oltvai
, University of Pittsburgh Medical School, USA
Organization of Cellular Networks
Saturday, February 21
| 5:00PM - 7:00PM
Analysis of Regulatory Networks in Cancer Biology
Room: Red Cloud
Speaker 3 of 4
Luk Van Parijs
, Massachusetts Institute of Technology, USA
Novel Tumor Suppressor Genes Revealed by a Mammalian RNA Interference Screen
Saturday, February 21
| 5:00PM - 7:00PM
Analysis of Regulatory Networks in Cancer Biology
Room: Red Cloud
Speaker 4 of 4
Kent W. Hunter
, NCI, National Institutes of Health, USA
Integrating 'omic' Technologies to Interrogate the Molecular Basis of Mammary Tumor Metastasis
Saturday, February 21
| 7:00PM - 8:00PM
Social Hour
Room: Shavano/Torreys
Saturday, February 21
| 8:00PM - 11:00PM
Entertainment
Room: Shavano/Torreys
Saturday, February 21
| 8:00PM - 11:00PM
Cash Bar
Room: Shavano/Torreys
Sunday, February 22
| 10:26AM - 10:26AM
Departure
*Session Chair.
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