Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Nuclear Receptors: Development, Physiology and Disease (2010X8)
Nuclear Receptors: Orphan Brothers (2008Z1)
Nuclear Receptors: Orphan Brothers (2006X3)

Web Desc
Nuclear Receptors: Orphan Brothers joint with Nuclear Receptors: Steroid Sisters Organizer(s): David J. Mangelsdorf, Johan H. Auwerx and Holly A. Ingraham Date: February 28 - March 04, 2004 Location: Keystone Resort, Keystone, CO, USA Supported by Keystone Symposia For important information on the coronavirus, please click here Summary of Meeting: Upon completion of this conference, participants should be able to: - Have a general knowledge of the importance of nuclear receptors in health and disease, and as potential targets for drug discovery. - Compare the difference and similarity in the biochemical mechanisms of action used by the classic steroid/endocrine receptors and the orphan receptors. - Identify novel ligands and physiologic pathways for the orphan nuclear receptors. Characterize the latest structural/functional properties of receptors from the 3-D structures of their various domains complexed with ligands, cofactors, and DNA. - Have an understanding of the latest biological tools (e.g., animal models, novel ligands, structural information) and technologies (e.g., genomics, proteomics, ligand screening) available for nuclear receptor research. - Promote a productive interaction between academic labs and industry. - Bring together and foster the interaction between the field's leading experts and younger scientists and trainees, with a particular emphasis on the inclusion of under represented groups. Discounted Abstract Deadline: October 28 2003 Discounted Registration Deadline: December 29 2003 We gratefully acknowledge additional support for this conference from: X-Ceptor Therapeutics, Inc. We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 1R13DK066661-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Nuclear Receptors: Orphan Brothers

joint with Nuclear Receptors: Steroid Sisters

Organizer(s): David J. Mangelsdorf, Johan H. Auwerx and Holly A. Ingraham

Date: February 28 - March 04, 2004
Location: Keystone Resort, Keystone, CO, USA

Supported by Keystone Symposia

For important information on the coronavirus, please click here

Summary of Meeting:

Upon completion of this conference, participants should be able to: - Have a general knowledge of the importance of nuclear receptors in health and disease, and as potential targets for drug discovery. - Compare the difference and similarity in the biochemical mechanisms of action used by the classic steroid/endocrine receptors and the orphan receptors. - Identify novel ligands and physiologic pathways for the orphan nuclear receptors. Characterize the latest structural/functional properties of receptors from the 3-D structures of their various domains complexed with ligands, cofactors, and DNA. - Have an understanding of the latest biological tools (e.g., animal models, novel ligands, structural information) and technologies (e.g., genomics, proteomics, ligand screening) available for nuclear receptor research. - Promote a productive interaction between academic labs and industry. - Bring together and foster the interaction between the field's leading experts and younger scientists and trainees, with a particular emphasis on the inclusion of under represented groups.

Discounted Abstract Deadline: October 28 2003

Discounted Registration Deadline: December 29 2003

We gratefully acknowledge additional support for this conference from:

X-Ceptor Therapeutics, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK066661-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Saturday, February 28 \| 3:00PM - 7:00PM Registration Room: Longs Peak Foyer
Saturday, February 28 \| 6:15PM - 7:15PM Refreshments Room: Longs Peak Foyer
Saturday, February 28 \| 7:15PM - 7:30PM Orientation Room: Red Cloud/Shavano/Torreys
Saturday, February 28 \| 7:30PM - 8:30PM Keynote Address (Joint) Room: Red Cloud/Shavano/Torreys Speaker 1 of 2 * David J. Mangelsdorf, University of Texas Southwestern Medical Center, USA
Saturday, February 28 \| 7:30PM - 8:30PM Keynote Address (Joint) Room: Red Cloud/Shavano/Torreys Speaker 2 of 2 Steven L. McKnight, University of Texas Southwestern Medical Center, USA Reciprocal Coupling of Metabolism and Circadian Rhythm
Sunday, February 29 \| 7:00AM - 8:00AM Breakfast Room: Grays/Long/Quandary
Sunday, February 29 \| 8:00AM - 11:00AM Neuroendocrine Regulators Room: Red Cloud Speaker 1 of 6 * Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland
Sunday, February 29 \| 8:00AM - 11:00AM Neuroendocrine Regulators Room: Red Cloud Speaker 2 of 6 Holly A. Ingraham, University of California, San Francisco, USA Orphan Nuclear Receptors of Subfamily V – Gene Dosage Effects and Ligand Independent Modulation
Sunday, February 29 \| 8:00AM - 11:00AM Neuroendocrine Regulators Room: Red Cloud Speaker 3 of 6 Thomas Perlmann, Karolinska Institutet, Ludwig Institute for Cancer Research, Sweden Ligand-Independent Nuclear Receptors in the CNS
Sunday, February 29 \| 8:00AM - 11:00AM Neuroendocrine Regulators Room: Red Cloud Speaker 4 of 6 Orla M. Conneely, Baylor College of Medicine, USA Essential and Redundant Roles of Nor-1 and Nur77 in Regulation of Myelopoiesis
Sunday, February 29 \| 8:00AM - 11:00AM Neuroendocrine Regulators Room: Red Cloud Speaker 5 of 6 Ueli Schibler, University of Geneva, Switzerland Nuclear Receptors and Circadian Rhythms
Sunday, February 29 \| 8:00AM - 11:00AM Neuroendocrine Regulators Room: Red Cloud Speaker 6 of 6 Timo Kanzleiter, German Institute of Human Nutrition, Germany Short Talk: An Orphan in the Cold: A Putative Function of Nur77 for Adaptive Thermogenesis in Brown Adipose Tissue
Sunday, February 29 \| 8:00AM - 11:00AM General Steroid Hormone Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 6 * Adriana Maggi, University of Milan, Italy
Sunday, February 29 \| 8:00AM - 11:00AM General Steroid Hormone Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 6 John W. Funder, Prince Henry's Institute of Medical Research, Australia Aldosterone, Cardiovascular Damage: The New Biology of Mineralocorticoid Receptors
Sunday, February 29 \| 8:00AM - 11:00AM General Steroid Hormone Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 6 Donald P. McDonnell, Duke University School of Medicine, USA The Efficacy of Agonist Activated Nuclear Receptors is Dramatically Enhanced by Exposure to Short Chain Fatty Acids in vitro and in vivo
Sunday, February 29 \| 8:00AM - 11:00AM General Steroid Hormone Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 6 Shigeaki Kato, University of Tokyo, Japan Co-Regulator and Chromatin Remodeling Complexes for Nuclear Receptors
Sunday, February 29 \| 8:00AM - 11:00AM General Steroid Hormone Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 6 Olli A. Jänne, University of Helsinki, Finland Sumoylation in Androgen Receptor Signaling
Sunday, February 29 \| 8:00AM - 11:00AM General Steroid Hormone Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 6 of 6 Debu Chakravarti, Northwestern University, Feinberg School of Medicine, USA Short Talk: Translating the Histone Code of Transcription
Sunday, February 29 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Sunday, February 29 \| 11:00AM - 1:00PM Poster Setup Room: Grays/Longs/Quandary
Sunday, February 29 \| 1:00PM - 10:00PM Poster Viewing Room: Grays/Longs/Quandary
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 Room: Red Cloud Speaker 1 of 5 * Holly A. Ingraham, University of California, San Francisco, USA
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 Room: Red Cloud Speaker 2 of 5 Kim Jongsook Kemper, University of Illinois at Urbana-Champaign, USA A Corepressor mSin3A-Swi/Snf Human Chromatin Remodeling Complex Mediates Repressor SHP Action in Cholesterol/Bile Acid Metabolism
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 Room: Red Cloud Speaker 3 of 5 Janet M. Allen, University College Dublin, Ireland Beyond the 48: Identification of Novel Nuclear Receptors
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 Room: Red Cloud Speaker 4 of 5 Yuriy Shostak, Acropolis, USA In vitro Genomic Selection: From the C. elegans Genome, to DAF-12 Binding Sites and Response Elements, to Target Genes
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 Room: Red Cloud Speaker 5 of 5 Michael R. Downes, The Salk Institute, USA A Chemical, Genetic and Structural Analysis of the Nuclear Bile Acid Receptor FXR
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 5 * Michael J. Garabedian, New York University School of Medicine, USA
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 5 István Szatmári, University of Debrecen, Hungary Retinoids Affect Differentiation and Function of Human Monocyte-Derived Dendritic Cells
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 5 Wilson H. Miller, Jr., McGill University, Canada Expression of SMRTbeta Promotes Ligand-Induced Activation of Mutated and Wild-Type Retinoid Receptors
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 5 Martin L. Privalsky, University of California, Davis, USA Isotype-Specificity in the Nuclear Receptor/Corepressor Interaction and in Transcriptional Repression
Sunday, February 29 \| 3:00PM - 4:00PM Hot Topics 1 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 5 Rob Jam Michalides, Netherlands Cancer Institute, Netherlands Tamoxifen Resistance by a Conformational Arrest of the Estrogen Receptor-alpha after PKA Activation in Breast Cancer: Mechanism of Anti-Estrogen Resistance in Breast Cancer
Sunday, February 29 \| 4:30PM - 5:00PM Coffee & Snacks Available Room: Longs Peak Foyer
Sunday, February 29 \| 5:00PM - 7:00PM Transcription and Chromatin (Joint) Room: Red Cloud/Shavano/Torreys Speaker 1 of 4 * Ronald M. Evans, HHMI/The Salk Institute, USA
Sunday, February 29 \| 5:00PM - 7:00PM Transcription and Chromatin (Joint) Room: Red Cloud/Shavano/Torreys Speaker 2 of 4 Beverly M. Emerson, CEDAR, OHSU Knight Cancer Institute, USA Specificity of Gene Regulation through Chromatin
Sunday, February 29 \| 5:00PM - 7:00PM Transcription and Chromatin (Joint) Room: Red Cloud/Shavano/Torreys Speaker 3 of 4 Gordon L. Hager, NCI, National Institutes of Health, USA Dynamic Interaction of Steroid Receptors with Gene Targets
Sunday, February 29 \| 5:00PM - 7:00PM Transcription and Chromatin (Joint) Room: Red Cloud/Shavano/Torreys Speaker 4 of 4 Robert G. Roeder, Rockefeller University, USA Integrated Functions of Diverse Coactivators in Transcriptional Activation by Nuclear Receptors.
Sunday, February 29 \| 7:00PM - 8:00PM Social Hour Room: Grays/Longs/Quandary
Sunday, February 29 \| 7:30PM - 10:00PM Poster Session 1 Room: Grays/Longs/Quandary
Monday, March 01 \| 7:00AM - 8:00AM Breakfast Room: Grays/Long/Quandary
Monday, March 01 \| 8:00AM - 11:00AM Enterohepatic Metabolism Room: Red Cloud Speaker 1 of 5 David D. Moore, Baylor College of Medicine, USA Mechanisms of Action of Nongenotoxic CARcinogens
Monday, March 01 \| 8:00AM - 11:00AM Enterohepatic Metabolism Room: Red Cloud Speaker 2 of 5 Steven A. Kliewer, University of Texas Southwestern Medical Center, USA Regulatory Actions of Enterohepatic Nuclear Receptors
Monday, March 01 \| 8:00AM - 11:00AM Enterohepatic Metabolism Room: Red Cloud Speaker 3 of 5 Brandee Wagner, Metacrine, USA Metabolic Regulation by Orphan Nuclear Receptors
Monday, March 01 \| 8:00AM - 11:00AM Enterohepatic Metabolism Room: Red Cloud Speaker 4 of 5 Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland Entero Hepatic Receptors and Homeostatic Control
Monday, March 01 \| 8:00AM - 11:00AM Enterohepatic Metabolism Room: Red Cloud Speaker 5 of 5 * Frank J. Gonzalez, National Institutes of Health, USA Short Talk: Exploring PPAR Function
Monday, March 01 \| 8:00AM - 11:00AM Progesterone and Estrogen Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 5 * Dean P. Edwards, Baylor College of Medicine, USA Extranuclear Signaling Mechanisms and Functions of the Progesterone Receptor
Monday, March 01 \| 8:00AM - 11:00AM Progesterone and Estrogen Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 5 Adriana Maggi, University of Milan, Italy Mechanisms of Estrogen Receptor Activation in vivo
Monday, March 01 \| 8:00AM - 11:00AM Progesterone and Estrogen Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 5 Benita S. Katzenellenbogen, University of Illinois, USA Estrogen Receptors: Structure-Activity Relationships and Regulation of Gene Expression
Monday, March 01 \| 8:00AM - 11:00AM Progesterone and Estrogen Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 5 Phyllis M. Wise, University of California, Davis, USA Novel Actions of Estrogens: Protective or Risk Factors in Brain Function
Monday, March 01 \| 8:00AM - 11:00AM Progesterone and Estrogen Action This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 5 Evan Simpson, Prince Henry's Institute, Australia Short Talk: LRH-1 and SHP Roles in Estrogen Regulation and the Metabolic Syndrome
Monday, March 01 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Monday, March 01 \| 11:00AM - 1:00PM Poster Setup Room: Grays/Longs/Quandary
Monday, March 01 \| 1:00PM - 10:00PM Poster Viewing Room: Grays/Longs/Quandary
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 Room: Red Cloud Speaker 1 of 4 Toshiya Tanaka, University of Tokyo, Japan Activation of Peroxisome Proliferator-Activated Receptor delta Induces Fatty Acid beta-oxidation in Skeletal Muscle and Attenuates Diet-Induced Obesity and Insulin Resistance
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 Room: Red Cloud Speaker 2 of 4 Bernard R. Pipy, France Role of PPARgamma in Induction of Macrophage Mannose Receptor Gene Expression: Implication in the Control of Gastrointestinal Candidosis in Normal and Immunodeficient RAG-2-/- Mice
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 Room: Red Cloud Speaker 3 of 4 * George E.O. Muscat, University of Queensland, Australia RORalpha (NR1F1) Regulates the Expression of Genes Involved in Lipid Catabolism, Cholesterol and Energy Homeostasis in Skeletal Muscle Cells
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 Room: Red Cloud Speaker 4 of 4 A Novel CAR-Mediated and CYP3A-Independent Pathway of Bile Acid Detoxification
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 4 * Carol A. Lange, University of Minnesota, USA Progestin and Mitogen Activated Protein Kinase (MAPK) Dependent Changes in Cell Cycle Regulation in Human Breast Cancer Cells
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 4 Cem Elbi, Merrimack Pharmaceuticals, USA Molecular Chaperones Function as Steroid Receptor Nuclear Mobility Factors
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 4 Raymond Blind, Vanderbilt University School of Medicine, USA Regulation of Glucocorticoid Receptor-Mediated Transcriptional activation: The Role of Receptor Phosphorylation and Cofactor Recruitment
Monday, March 01 \| 3:00PM - 4:00PM Hot Topics 2 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 4 Dennis H. Dowhan, Baylor College of Medicine, USA Regulation of Steroid Hormone Receptor Mediated Alternative Splicing by U2AF-Related Proteins CAPER & CAPERb
Monday, March 01 \| 4:30PM - 5:00PM Coffee & Snacks Available Room: Longs Peak Foyer
Monday, March 01 \| 5:00PM - 7:00PM Nuclear Receptor Coregulators (Joint) Room: Red Cloud/Shavano/Torreys Speaker 1 of 4 * Bert W. O'Malley, Baylor College of Medicine, USA
Monday, March 01 \| 5:00PM - 7:00PM Nuclear Receptor Coregulators (Joint) Room: Red Cloud/Shavano/Torreys Speaker 2 of 4 Keith R. Yamamoto, University of California, San Francisco, USA Hormones and Response Elements: Two Receptor Ligands that Together Specify Functional Surfaces and Trascriptional Regulatory Networks
Monday, March 01 \| 5:00PM - 7:00PM Nuclear Receptor Coregulators (Joint) Room: Red Cloud/Shavano/Torreys Speaker 3 of 4 Christopher K. Glass, University of California, San Diego, USA Nuclear Receptors and Inflammation
Monday, March 01 \| 5:00PM - 7:00PM Nuclear Receptor Coregulators (Joint) Room: Red Cloud/Shavano/Torreys Speaker 4 of 4 Bruce M. Spiegelman, Harvard Medical School, USA OXPHOS Pathway Dysregulated in Human Diabetes is Controlled by PGC-1 Coactivation
Monday, March 01 \| 7:00PM - 8:00PM Social Hour Room: Grays/Longs/Quandary
Monday, March 01 \| 7:30PM - 10:00PM Poster Session 2 Room: Grays/Longs/Quandary
Tuesday, March 02 \| 7:00AM - 8:00AM Breakfast Room: Grays/Long/Quandary
Tuesday, March 02 \| 8:00AM - 11:00AM Developmental Regulators Room: Red Cloud Speaker 1 of 5 Carl S. Thummel, University of Utah School of Medicine, USA Molecular Mechanisms of Hormone Signaling and Nuclear Receptor Function in Drosophila
Tuesday, March 02 \| 8:00AM - 11:00AM Developmental Regulators Room: Red Cloud Speaker 2 of 5 Ann E. Sluder, Cambria Biosciences LLC, USA Nematode Nuclear Receptors: Conservation, Variation and Function
Tuesday, March 02 \| 8:00AM - 11:00AM Developmental Regulators Room: Red Cloud Speaker 3 of 5 Vincent Giguère, McGill University, Canada Molecular Mechanisms and Functional Genomics of ERR/PGC-1 Interaction in Metabolic Control
Tuesday, March 02 \| 8:00AM - 11:00AM Developmental Regulators Room: Red Cloud Speaker 4 of 5 Carole R. Mendelson, University of Texas Southwestern Medical Center, USA Regulation of Mammalian Parturition by Nuclear Receptors and Coactivators
Tuesday, March 02 \| 8:00AM - 11:00AM Developmental Regulators Room: Red Cloud Speaker 5 of 5 * Austin J. Cooney, Baylor College of Medicine, USA Short Talk: Reciprocal Regulation of Oct4 Expression by the Orphan Receptors LRH-1 and GCNF
Tuesday, March 02 \| 8:00AM - 11:00AM Vitamin D and T3 Receptors This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 5 Jacques Samarut, Centre National de la Recherche Scientifique, France Roles of Thyroid Hormone Receptor Isoforms in Mouse Development
Tuesday, March 02 \| 8:00AM - 11:00AM Vitamin D and T3 Receptors This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 5 * Leonard P. Freedman, Global Biological Standards Institute, USA Nuclear Receptor Coactivators: It's Hip to be DRIP
Tuesday, March 02 \| 8:00AM - 11:00AM Vitamin D and T3 Receptors This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 5 Catherine C. Thompson, Pfizer, USA Multiple Roles of the Corepressor Hairless in Nuclear Receptor Signaling
Tuesday, March 02 \| 8:00AM - 11:00AM Vitamin D and T3 Receptors This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 5 Judah S. Denburg, McMaster University, Canada Selective Thyroid Hormone Analogs
Tuesday, March 02 \| 8:00AM - 11:00AM Vitamin D and T3 Receptors This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 5 Myles Brown, Dana-Farber Cancer Institute, USA Short Talk: Coactivator as Oncogene
Tuesday, March 02 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Tuesday, March 02 \| 11:00AM - 1:00PM Poster Setup Room: Grays/Longs/Quandary
Tuesday, March 02 \| 1:00PM - 10:00PM Poster Viewing Room: Grays/Longs/Quandary
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 Room: Red Cloud Speaker 1 of 5 Lena Jendeberg, Biovitrum, Sweden Structural Insights into the Heterodimeric Complex of LXRa and RXRb Ligand-Binding Domains in a Fully Agonistic Conformation
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 Room: Red Cloud Speaker 2 of 5 Andrew I. Shulman, University of Texas Southwestern Medical Center, USA Molecular Basis of Allosteric Ligand Activation in RXR Heterodimers
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 Room: Red Cloud Speaker 3 of 5 * Frances M. Sladek, University of California, Riverside, USA Comparison of HNF4 Binding Sites in the Human and Mouse Genomes
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 Room: Red Cloud Speaker 4 of 5 Souphatta Sasorith, Institut de Genetique et de Biologie Moleculaire et Cellulaire(IGBMC), France 3D Nuclear Receptors Thematic Database
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 Room: Red Cloud Speaker 5 of 5 Yanhong Shi, Beckman Research Institute of City of Hope, USA The Expression and Function of Orphan Nuclear Receptor TLX in Adult Neural Stem Cells
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 5 * Karen E. Knudsen, Thomas Jefferson University, Kimmel Cancer Center, USA
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 5 Kevin Link, Cincinnati Children's Hospital Medical Center, USA SWI/SNF is Required for Co-Activator Stimulated Androgen Receptor Activation
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 5 Catherine F. Teyssier, INSERM EMI 0229, France Regulation of PGC-1 Coactivator Activity by Arginine Methylation
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 5 Paul M. Yen, Johns Hopkins University, USA Cyclical Recruitment of TFIIH Subunits and other Co-Activators to Thyroid Hormone Response Elements (TREs): Evidence for 'Signature' Coactivator Profiles in Target Gene Regulation
Tuesday, March 02 \| 3:00PM - 4:00PM Hot Topics 3 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 5 Michael A. Mancini, Baylor College of Medicine, USA Transcription Factor Dynamics on Integrated Prolactin Promoter-Enhancer Arrays
Tuesday, March 02 \| 4:30PM - 5:00PM Coffee & Snacks Available Room: Longs Peak Foyer
Tuesday, March 02 \| 5:00PM - 7:00PM 3-D Structure (Joint) Room: Red Cloud/Shavano/Torreys Speaker 1 of 5 * Donald P. McDonnell, Duke University School of Medicine, USA
Tuesday, March 02 \| 5:00PM - 7:00PM 3-D Structure (Joint) Room: Red Cloud/Shavano/Torreys Speaker 2 of 5 Timothy M. Willson, GlaxoSmithKline, USA Are All Orphan Nuclear Receptors Good Drug Targets?
Tuesday, March 02 \| 5:00PM - 7:00PM 3-D Structure (Joint) Room: Red Cloud/Shavano/Torreys Speaker 3 of 5 Jean-Paul Renaud, NovAliX, France Orphan nuclear receptor characterization through structural studies
Tuesday, March 02 \| 5:00PM - 7:00PM 3-D Structure (Joint) Room: Red Cloud/Shavano/Torreys Speaker 4 of 5 Geoffrey L. Greene, University of Chicago, USA Short Talk: ERalpha/ERbeta Ligand Discrimination and Allosteric Communication between Ligand, Receptor and Co-Regulators
Tuesday, March 02 \| 5:00PM - 7:00PM 3-D Structure (Joint) Room: Red Cloud/Shavano/Torreys Speaker 5 of 5 Ronald N. Margolis, NIDDK, National Institutes of Health, USA Short Talk: The Nuclear Receptor Signaling Atlas: Building a Comprehensive Atlas of Orphan and Nuclear Receptor Function
Tuesday, March 02 \| 7:00PM - 8:00PM Social Hour Room: Grays/Longs/Quandary
Tuesday, March 02 \| 7:30PM - 10:00PM Poster Session 3 Room: Grays/Longs/Quandary
Wednesday, March 03 \| 7:00AM - 8:00AM Breakfast Room: Grays/Long/Quandary
Wednesday, March 03 \| 8:00AM - 11:00AM Intermediary Metabolism Room: Red Cloud Speaker 1 of 5 David J. Mangelsdorf, University of Texas Southwestern Medical Center, USA Orphan Brother, Where Art Thou?
Wednesday, March 03 \| 8:00AM - 11:00AM Intermediary Metabolism Room: Red Cloud Speaker 2 of 5 Daniel Metzger, Institut de Génétique et de Biologie Molécullaire et Cellulaire, Strasbourg, France Functional Role of RXRs and PPARgamma in Adipocytes
Wednesday, March 03 \| 8:00AM - 11:00AM Intermediary Metabolism Room: Red Cloud Speaker 3 of 5 Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA Nuts and Bolts of Repression
Wednesday, March 03 \| 8:00AM - 11:00AM Intermediary Metabolism Room: Red Cloud Speaker 4 of 5 Peter Tontonoz, University of California, Los Angeles, USA Orphan Nuclear Receptors in Atherosclerosis
Wednesday, March 03 \| 8:00AM - 11:00AM Intermediary Metabolism Room: Red Cloud Speaker 5 of 5 * Malcolm G. Parker, Imperial College London, UK Short Talk: Role of RIP140 Corepressor in Adipose Biology
Wednesday, March 03 \| 8:00AM - 11:00AM Steroid Receptors and Disease This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 5 Frank Gannon, QIMR Berghofer Medical Research Institute, Australia Estrogen Receptor-a Directs Cyclical Epigenetic Processes on a Natural Promoter through the Ordered, Combinatorial Recruitment of Cofactors
Wednesday, March 03 \| 8:00AM - 11:00AM Steroid Receptors and Disease This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 5 J. Wesley Pike, University of Wisconsin-Madison, USA Molecular Actions of Vitamin D and Its Analogs in Transcriptional Regulation
Wednesday, March 03 \| 8:00AM - 11:00AM Steroid Receptors and Disease This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 5 Kenneth S. Korach, NIEHS, National Institutes of Health, USA Physiological Disruption Due to Loss of Functional Estrogen Receptors
Wednesday, March 03 \| 8:00AM - 11:00AM Steroid Receptors and Disease This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 5 Jan-Åke Gustafsson, University of Houston, USA New Roles of Estrogen Receptor Beta
Wednesday, March 03 \| 8:00AM - 11:00AM Steroid Receptors and Disease This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 5 * Heather A. Harris, Wyeth Pharmaceuticals, USA Short Talk: Selective Estrogen Receptor-Beta Agonists are Potent Anti-Inflammatory Agents
Wednesday, March 03 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 Room: Red Cloud Speaker 1 of 4 * Bruce Blumberg, University of California, Irvine, USA Vitamin K2 Regulation of Bone Homeostasis is Mediated by the Steroid and Xenobiotic Receptor, SXR
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 Room: Red Cloud Speaker 2 of 4 David Hervé Volle, Institut de Génétique et de Biologie Moléculaire et Cellulaire, France Testicular Function in LXR-Deficient Mice
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 Room: Red Cloud Speaker 3 of 4 Jae In Lee, Amgen Inc., USA ASC-2, as an Essential Transcriptional Coactivator of the Liver X Receptors in vivo
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 Room: Red Cloud Speaker 4 of 4 Hilde Irene Nebb, University of Oslo, Norway Liver X Receptor Signaling Pathways in Adipose Tissue
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 1 of 5 * E. Brad Thompson, University of Texas Medical Branch, USA
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 2 of 5 Raj Kumar, Commonwealth Medical College, USA Induced alpha-Helix Structure in the AF1 of the Steroid Receptors Upon Direct Binding to Cofactor Protein
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 3 of 5 Eugene Hur, University of California, San Francisco, USA Accommodation and Discrimination of Hydrophobic Motifs in the Androgen Receptor
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 4 of 5 Fraydoon Rastinejad, University of Oxford, UK Structural Basis for Bile Acid Binding and Activation of FXR
Wednesday, March 03 \| 3:30PM - 4:30PM Hot Topics 4 This session is from Nuclear Receptors: Steroid Room: Shavano/Torreys Speaker 5 of 5 Timothy R. Geistlinger, Amyris, USA Specific Proteomimetic Inhibitors of NR:SCR
Wednesday, March 03 \| 5:00PM - 5:30PM Coffee & Snacks Available Room: Longs Peak Foyer
Wednesday, March 03 \| 5:30PM - 7:30PM Nuclear Receptor Round-Up (Joint). Session Sponsored in part by X-Ceptor Therapeutics, Inc. Room: Red Cloud/Shavano/Torreys Speaker 1 of 3 * David J. Mangelsdorf, University of Texas Southwestern Medical Center, USA
Wednesday, March 03 \| 5:30PM - 7:30PM Nuclear Receptor Round-Up (Joint). Session Sponsored in part by X-Ceptor Therapeutics, Inc. Room: Red Cloud/Shavano/Torreys Speaker 2 of 3 Bert W. O'Malley, Baylor College of Medicine, USA Searching for Novel and Diverse Functions of Steroid Hormone Receptor Coactivators
Wednesday, March 03 \| 5:30PM - 7:30PM Nuclear Receptor Round-Up (Joint). Session Sponsored in part by X-Ceptor Therapeutics, Inc. Room: Red Cloud/Shavano/Torreys Speaker 3 of 3 Ronald M. Evans, HHMI/The Salk Institute, USA Nuclear Receptors: The Final Word
Wednesday, March 03 \| 7:30PM - 8:00PM Social Hour Room: Grays/Longs/Quandary
Wednesday, March 03 \| 8:00PM - 11:00PM Entertainment Room: Grays/Longs/Quandary
Wednesday, March 03 \| 8:00PM - 11:00PM Cash Bar Room: Grays/Longs/Quandary
Thursday, March 04 \| 10:21AM - 10:21AM Departure *Session Chair †Invited, not yet responded.