Web Desc
The Pathogen-Host Standoff: Persistent and Latent Infection
joint with Immune Evasion
Organizer(s): JoAnne L. Flynn and Edward S. Mocarski Jr.
Date: March 25 - 30, 2004
Location: Taos Convention Center (meeting only), Taos, NM, USA
Sponsored by Roche Diagnostics
Summary of Meeting:
The goals for this meeting include: - ·Understanding common themes in latent microbial infections, regardless of whether the microbe is a virus, bacterium, parasite, worm, or fungus. - Addressing questions of memory during chronic or latent infection and contrast that with memory in acute infection (important in design of vaccine or treatment strategies). - Understanding common immune mechanisms important in controlling or eliminating latent or persistent infections - ·Identifying mechanisms by which pathogens escape detection or elimination by the immune system, and design strategies to circumvent these pathogens (vaccine or drug development). - Bringing together scientists from different fields to think about the concepts of latency and persistence, and share ideas from different fields. Major and pivotal problems in the field to be addressed include: - How to effectively enhance an immune response to eliminate an organism that has evolved to be persistent in the host. - Adapting the information about the immune response to the setting of chronic or latent infections. - Identifying the persistent or latent state of the microbe, and determining the genetic components that contribute to latency.
Discounted Abstract Deadline: November 24 2003
Discounted Registration Deadline: January 26 2004
We gratefully acknowledge additional support for this conference from:
Burroughs Wellcome FundRoche Diagnostics GmbHThe Ellison Medical Foundation
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 U13 AI60000-01

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI058468-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Thursday, March 25 | 3:00PM - 7:00PM
Registration
Room: Rio Grande D


Thursday, March 25 | 6:15PM - 7:15PM
Refreshments
Room: Rio Grande A-C


Thursday, March 25 | 7:15PM - 7:20PM
Orientation
Room: Bataan


Thursday, March 25 | 7:20PM - 7:30PM
Introductory Remarks
Room: Bataan

Speaker 1 of 1
JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA

Thursday, March 25 | 7:30PM - 9:30PM
Keynote Session (Joint). Keynote Session Sponsored by The E
llison Medical Foundation
Room: Bataan

Speaker 1 of 4
* Edward S. Mocarski, Emory University, USA

Thursday, March 25 | 7:30PM - 9:30PM
Keynote Session (Joint). Keynote Session Sponsored by The E
llison Medical Foundation
Room: Bataan

Speaker 2 of 4
* Anne O'Garra, Francis Crick Institute, UK

Thursday, March 25 | 7:30PM - 9:30PM
Keynote Session (Joint). Keynote Session Sponsored by The E
llison Medical Foundation
Room: Bataan

Speaker 3 of 4
Ulrich H. Koszinowski, Max Von Pettenkofer Institut, Germany
Mechanisms of Immunoevasion in Cytomegalovirus

Thursday, March 25 | 7:30PM - 9:30PM
Keynote Session (Joint). Keynote Session Sponsored by The E
llison Medical Foundation
Room: Bataan

Speaker 4 of 4
Stanley Falkow, Stanford University, USA
Persistent Bacterial Infection

Friday, March 26 | 7:00AM - 8:00AM
Breakfast
Room: Bataan


Friday, March 26 | 8:00AM - 11:15AM
Host Control of Persistence. Session Sponsored by The Ellis
on Medical Foundation

Room: Rio Grande A-B

Speaker 1 of 6
Rafi Ahmed, Emory University School of Medicine, USA
Memory CD8 T Cell Differentiation

Friday, March 26 | 8:00AM - 11:15AM
Host Control of Persistence. Session Sponsored by The Ellis
on Medical Foundation

Room: Rio Grande A-B

Speaker 2 of 6
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Role of Regulatory T Cells in Persistnet Infections

Friday, March 26 | 8:00AM - 11:15AM
Host Control of Persistence. Session Sponsored by The Ellis
on Medical Foundation

Room: Rio Grande A-B

Speaker 3 of 6
Leo Lefrançois, University of Connecticut Health Center, USA
The Control of Memory CD8T Cell Persistence by IL15

Friday, March 26 | 8:00AM - 11:15AM
Host Control of Persistence. Session Sponsored by The Ellis
on Medical Foundation

Room: Rio Grande A-B

Speaker 4 of 6
* JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA
TNF and Tuberculosis

Friday, March 26 | 8:00AM - 11:15AM
Host Control of Persistence. Session Sponsored by The Ellis
on Medical Foundation

Room: Rio Grande A-B

Speaker 5 of 6
J. Scott McClellan, Washington University School of Medicine, USA
Short Talk: A Beta-2-Microglobulin-dependent but MHC Class Ia-Independent Mechanism is Essential for Control of Chronic Gamma-Herpesvirus Infection

Friday, March 26 | 8:00AM - 11:15AM
Host Control of Persistence. Session Sponsored by The Ellis
on Medical Foundation

Room: Rio Grande A-B

Speaker 6 of 6
Wendy P. Loomis, Harvard Medical School, USA
Short Talk: GILT, A Lysosomal Thiol Reductase, is Required for the Priming of Microbe-Specific CD8+ T Cells

Friday, March 26 | 8:00AM - 11:15AM
Role of Antigen Presenting Cells in Immunoregulation, Immuno
deviation and Tolerance. Session Sponsored in part by Schering-Plough Laboratory for Immunological Research
This session is from Immune Evasion

Room: Rio Grande C-D

Speaker 1 of 6
Brian L. Kelsall, NIAID, National Institutes of Health, USA
Inhibitory Pathways for Controlling Dendritic Cell Functions


Friday, March 26 | 8:00AM - 11:15AM
Role of Antigen Presenting Cells in Immunoregulation, Immuno
deviation and Tolerance. Session Sponsored in part by Schering-Plough Laboratory for Immunological Research
This session is from Immune Evasion

Room: Rio Grande C-D

Speaker 2 of 6
Andrea la Sala, NIAID, National Institutes of Health, USA
Short Talk: Inhibition of Interleukin(IL)-12 Production by Gi-Protein Coupled Receptors is Mediated by Phosphoinositide-3 Kinase (PI3K) Activation, Phosphorylation of Protein Kinase B/ AKT, and Activation of c-Jun N-Terminal Kinase


Friday, March 26 | 8:00AM - 11:15AM
Role of Antigen Presenting Cells in Immunoregulation, Immuno
deviation and Tolerance. Session Sponsored in part by Schering-Plough Laboratory for Immunological Research
This session is from Immune Evasion

Room: Rio Grande C-D

Speaker 3 of 6
* Ralph M. Steinman, Rockefeller University, USA
Control of Immunity and Tolerance by Dendritic Cells in vivo


Friday, March 26 | 8:00AM - 11:15AM
Role of Antigen Presenting Cells in Immunoregulation, Immuno
deviation and Tolerance. Session Sponsored in part by Schering-Plough Laboratory for Immunological Research
This session is from Immune Evasion

Room: Rio Grande C-D

Speaker 4 of 6
Hyam I. Levitsky, Century Therapeutics, USA
Reconciling the Tumor Immunosurveillance Hypothesis, Immunoediting, and the Barrier of Tumor-Specific T cell Tolerance


Friday, March 26 | 8:00AM - 11:15AM
Role of Antigen Presenting Cells in Immunoregulation, Immuno
deviation and Tolerance. Session Sponsored in part by Schering-Plough Laboratory for Immunological Research
This session is from Immune Evasion

Room: Rio Grande C-D

Speaker 5 of 6
Matthew L. Albert, Genentech, Inc., USA
Molecular and Cellular Requirements for Cross-Priming versus Cross-Tolerance


Friday, March 26 | 8:00AM - 11:15AM
Role of Antigen Presenting Cells in Immunoregulation, Immuno
deviation and Tolerance. Session Sponsored in part by Schering-Plough Laboratory for Immunological Research
This session is from Immune Evasion

Room: Rio Grande C-D

Speaker 6 of 6
P'ng Loke, New York University School of Medicine, USA
Short Talk: The Role of Adaptive Immunity in the Recruitment/Differentiation of Alternatively Activated Macrophages


Friday, March 26 | 9:20AM - 9:40AM
Coffee Break
Room: Bataan


Friday, March 26 | 11:15AM - 1:00PM
Poster Setup
Room: Bataan


Friday, March 26 | 1:00PM - 10:00PM
Poster Viewing
Room: Bataan


Friday, March 26 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Bataan


Friday, March 26 | 5:00PM - 7:00PM
Persistence in the Face of Innate Immunity: The Oldest Profe
ssion?

Room: Rio Grande A-B

Speaker 1 of 4
* Lewis L. Lanier, University of California, San Francisco, USA
NK Cell Recognition of Cytomegalovirus

Friday, March 26 | 5:00PM - 7:00PM
Persistence in the Face of Innate Immunity: The Oldest Profe
ssion?

Room: Rio Grande A-B

Speaker 2 of 4
Grant McFadden, University of Florida, USA
Immune Evasion Strategies by Poxviruses

Friday, March 26 | 5:00PM - 7:00PM
Persistence in the Face of Innate Immunity: The Oldest Profe
ssion?

Room: Rio Grande A-B

Speaker 3 of 4
Ann B. Hill, Oregon Health & Science University, USA
MCMV Interference with Antigen Presentation does not Affect Size of CD8 T Cell Responses

Friday, March 26 | 5:00PM - 7:00PM
Persistence in the Face of Innate Immunity: The Oldest Profe
ssion?

Room: Rio Grande A-B

Speaker 4 of 4
Nancy J. Raab-Traub, University of North Carolina at Chapel Hill, USA
Short Talk: Potential Immune Selection of EBV LMP1 in Nasopharyigeal Carcinoma

Friday, March 26 | 5:00PM - 7:00PM
Immunoprivileged Sites
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 2
Thomas A. Ferguson, Washington University School of Medicine, USA
Termination of Antigen Specific Immunity; What We Have Learned From Immune Privileged Sites


Friday, March 26 | 5:00PM - 7:00PM
Immunoprivileged Sites
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 2
Phillippe Le Bouteiller, INSERM, France
Human Cytomegalovirus-Placental HLA-G Interactions


Friday, March 26 | 7:00PM - 8:00PM
Social Hour
Room: Bataan


Friday, March 26 | 7:30PM - 10:00PM
Poster Session 1
Room: Bataan


Saturday, March 27 | 7:00AM - 8:00AM
Breakfast
Room: Rio Grande A-C


Saturday, March 27 | 8:00AM - 11:15AM
Dysregulation of the Immune Response by Pathogens (Joint).
Session Sponsored by the Burroughs Wellcome Fund.

Room: Bataan

Speaker 1 of 5
* Alan Sher, NIAID, National Institutes of Health, USA
Regulation of Immune Response in Chronic Infectino in Eukariotics

Saturday, March 27 | 8:00AM - 11:15AM
Dysregulation of the Immune Response by Pathogens (Joint).
Session Sponsored by the Burroughs Wellcome Fund.

Room: Bataan

Speaker 2 of 5
Maria Yazdanbakhsh, Leiden University Medical Center, Netherlands
Chronic Helminth Infections and Immune Evasion: Cellular and Molecular Mechanisms

Saturday, March 27 | 8:00AM - 11:15AM
Dysregulation of the Immune Response by Pathogens (Joint).
Session Sponsored by the Burroughs Wellcome Fund.

Room: Bataan

Speaker 3 of 5
Edward J. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany
Immune Response Polarization by Dendritic Cells

Saturday, March 27 | 8:00AM - 11:15AM
Dysregulation of the Immune Response by Pathogens (Joint).
Session Sponsored by the Burroughs Wellcome Fund.

Room: Bataan

Speaker 4 of 5
Gary B. Huffnagle, University of Michigan, USA
Mechanisms Underlying Chronic Fungal Infections and Allergies

Saturday, March 27 | 8:00AM - 11:15AM
Dysregulation of the Immune Response by Pathogens (Joint).
Session Sponsored by the Burroughs Wellcome Fund.

Room: Bataan

Speaker 5 of 5
Thomas B. Nutman, NIAID, National Institutes of Health, USA
Response of Human Dendritic, Macrophages and Langerhans’ Cells to Filarial Parasites

Saturday, March 27 | 9:20AM - 9:40AM
Coffee Break
Room: Rio Grande A-C


Saturday, March 27 | 1:00PM - 2:00PM
Poster Setup
Room: Bataan


Saturday, March 27 | 2:00PM - 10:00PM
Poster Viewing
Room: Bataan


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 8
Drake M. LaFace, Merck Research Labs - Palo Alto, USA
Recombinant Adenovirus Vectors Moderate Immune Evasion


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 8
Philippe Krebs, The Scripps Research Institute, USA
Functional Paralysis of Cytotoxic T Cells Following Immunization with Recombinant Adenovirus


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 3 of 8
Scott E. Hensley, NIAID, National Institutes of Health, USA
Viral Immune Evasion Genes of Adenoviral Vectors Affect their Efficiency as Vaccine Carriers


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 4 of 8
Paola Allavena, Instituto Clinico Humanitas, Italy
Cross-Linking of the Mannose Receptor on Monocyte-Derived Dendritic Cells Activates an Anti-Inflammatory Immuno-Suppressive Program


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 5 of 8
Karen H. Redlitz, University of Virginia, USA
Cytokine Regulation of Indoleamine 2,3-Dioxygenase Activity in Human Melanoma Cell Lines


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 6 of 8
Wu-Shiun Hou, Massachusetts Institute of Technology, USA
DC Survival and Immunogenicity is Differentially Regulated by Innate and Acquired Immune System Signals


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 7 of 8
Weiping Zou, University of Michigan, USA
Immune Evasion in Human Ovarian Cancer


Saturday, March 27 | 2:00PM - 4:00PM
Workshop 1
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 8 of 8
Jessica Carolyn Karl, National Cancer Institute, National Institutes of Health, USA
Tolerance in T Cell Depleted Host is Mediated by B Cells and Bone Marrow Stroma in the Presence of Classical Costimulation


Saturday, March 27 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Bataan


Saturday, March 27 | 5:00PM - 7:15PM
Persistence in the Face of Adaptive Immunity: A Mammalian Th
eme?

Room: Rio Grande A-B

Speaker 1 of 5
Philip D. Greenberg, University of Washington, USA
Mysteries of Cellular Immune Control of Viruses

Saturday, March 27 | 5:00PM - 7:15PM
Persistence in the Face of Adaptive Immunity: A Mammalian Th
eme?

Room: Rio Grande A-B

Speaker 2 of 5
* Robert L. Hendricks, University of Pittsburgh, USA
Retention of Memory CD8+ T Cells in Latent HSV-1 Infected Sensory Ganglia

Saturday, March 27 | 5:00PM - 7:15PM
Persistence in the Face of Adaptive Immunity: A Mammalian Th
eme?

Room: Rio Grande A-B

Speaker 3 of 5
Todd M. Allen, Ragon Institute of MGH, MIT and Harvard, USA
Impact of Viral Sequence Evolution on Immune Control of HIV-1 and HCV

Saturday, March 27 | 5:00PM - 7:15PM
Persistence in the Face of Adaptive Immunity: A Mammalian Th
eme?

Room: Rio Grande A-B

Speaker 4 of 5
Rama Rao Amara, Emory University, USA
Short Talk: Immune Control of HIV Persistence and Latency

Saturday, March 27 | 5:00PM - 7:15PM
Persistence in the Face of Adaptive Immunity: A Mammalian Th
eme?

Room: Rio Grande A-B

Speaker 5 of 5
Kim J. Hasenkrug, NIAID, National Institutes of Health, USA
Short Talk: Regulatory T Cells Suppress Anti-Viral CD8+ T Cell Functions and Contribute to Retroviral Persistence

Saturday, March 27 | 5:00PM - 7:15PM
Immunoregulatory T Cells
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 4
* Anne O'Garra, Francis Crick Institute, UK
Il-10-Sacreting Regulatory T Cells


Saturday, March 27 | 5:00PM - 7:15PM
Immunoregulatory T Cells
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 4
Anne E. Goldfeld, Children's Hospital Boston, Harvard Medical School, USA
Role of IL-10-Producing T Cells in the Pathogenesis of Tuberculosis


Saturday, March 27 | 5:00PM - 7:15PM
Immunoregulatory T Cells
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 3 of 4
Fiona M. Powrie, University of Oxford, UK
Immunoregulatory T Cells in Autoimmunity


Saturday, March 27 | 5:00PM - 7:15PM
Immunoregulatory T Cells
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 4 of 4
Dominique Kaiserlian, INSERM U851, France
Regulatory CD4+ T cells in Oral Tolerance


Saturday, March 27 | 7:15PM - 8:15PM
Social Hour
Room: Bataan


Saturday, March 27 | 7:30PM - 10:00PM
Poster Session 2
Room: Bataan


Sunday, March 28 | 7:00AM - 8:00AM
Breakfast
Room: Bataan


Sunday, March 28 | 8:00AM - 11:15AM
Pathogen Escape from Control
Room: Rio Grande A-B

Speaker 1 of 6
John M. Leong, University of Massachusetts Medical School, USA
Platelet Activation and High-Level Bacteremia by a Relapsing Fever Spirochete, Borrelia hermsii

Sunday, March 28 | 8:00AM - 11:15AM
Pathogen Escape from Control
Room: Rio Grande A-B

Speaker 2 of 6
Cliona M. Rooney, Baylor College of Medicine, USA
Overcoming Tumor Immune Evasion Strategies to Improve CTLs for the Adoptive Immunotherapy of EBV-Related Tumors

Sunday, March 28 | 8:00AM - 11:15AM
Pathogen Escape from Control
Room: Rio Grande A-B

Speaker 3 of 6
Kenneth L. Tyler, University of Colorado School of Medicine, USA
Reovirus Control of Intracellular Signaling and Apoptosis

Sunday, March 28 | 8:00AM - 11:15AM
Pathogen Escape from Control
Room: Rio Grande A-B

Speaker 4 of 6
* Edward S. Mocarski, Emory University, USA
Cytomegalovirus Control of Dissemination and Latency

Sunday, March 28 | 8:00AM - 11:15AM
Pathogen Escape from Control
Room: Rio Grande A-B

Speaker 5 of 6
Maaike E. Ressing, Leiden University Medical Center, Netherlands
Short Talk: Evasion from HLA Class II-Restricted T Cell Immunity during Lytic EBV Infection

Sunday, March 28 | 8:00AM - 11:15AM
Pathogen Escape from Control
Room: Rio Grande A-B

Speaker 6 of 6
Padraic Fallon, Trinity College Dublin, Ireland
Short Talk: Parasitic Helminth Subversion of Inflammation by a Chemokine-Binding Protein

Sunday, March 28 | 8:00AM - 11:00AM
Unresponsiveness and Immunosuppression in Cancer
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 3
Hans Schreiber, University of Chicago, USA
Solid Tumors: Overcoming Stromal Barriers and Immune Escape


Sunday, March 28 | 8:00AM - 11:00AM
Unresponsiveness and Immunosuppression in Cancer
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 3
Dmitry I. Gabrilovich, AstraZeneca, USA
Defective Dendritic Cell Differentiation and Function in Cancer


Sunday, March 28 | 8:00AM - 11:00AM
Unresponsiveness and Immunosuppression in Cancer
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 3 of 3
Alexander H. Enk, Universitäts-Hautklinik Heidelberg, Germany
DC, Tumors and Regulatory T Cells


Sunday, March 28 | 9:20AM - 9:40AM
Coffee Break
Room: Bataan


Sunday, March 28 | 11:15AM - 1:00PM
Poster Setup
Room: Bataan


Sunday, March 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Bataan


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 8
Niamh E. Mangan, Trinity College, Ireland
Novel Immune Modulation by Helminths Protects Mice from Allergic Diseases


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 8
Michael J. Brumlik, University of Texas Health Science Center, USA
Identification of a Gene Encoding a Novel Mitogen-Activated Protein Kinase in Toxoplasma gondii


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 3 of 8
Mark T. Orr, Infectious Disease Research Institute, USA
Restoring an Immune Evasion Strategy to Herpes Simplex Virus


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 4 of 8
David McKechnie Haig, Moredun Research Institute, UK
Immunomodulation by a gamma-Herpesvirus and a Parapoxvirus: A Tale of Two Interleukin-10s


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 5 of 8
W. L. William Chang, University of California, Davis, USA
Cytomegalovirus-Encoded IL-10: A Potential Immune Evasion Mechanism that Affects Immature and Mature Dendritic Cells


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 6 of 8
Elke Scandella, Kantonsspital St. Gallen, Switzerland
Impact of CCR7 on Function and Distribution of Antiviral Effector and Memory Cytotoxic T Lymphocytes


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 7 of 8
Jean-Luc Davignon, INSERM, France
Impairment of IFN-gamma-Induced Tyrosine Phosphorylation of STAT1 by HCMV through a New Mechanism


Sunday, March 28 | 2:00PM - 4:00PM
Workshop 2
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 8 of 8
Ramsey H. McIntire, University of Kansas Medical Center, USA
Recombinant Soluble HLA-G1 and -G2 Regulate Production of Anti-Inflammatory Cytokines by U937 Cells


Sunday, March 28 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Bataan


Sunday, March 28 | 5:00PM - 7:00PM
Challenges of the Intracellular Lifestyle
Room: Rio Grande A-B

Speaker 1 of 4
Bernard Roizman, University of Chicago, USA
The Strategy of Conquest of the Host Cell by Herpes Simplex Virus 1(HSV-1)

Sunday, March 28 | 5:00PM - 7:00PM
Challenges of the Intracellular Lifestyle
Room: Rio Grande A-B

Speaker 2 of 4
Nancy C. Reich, Stony Brook University, USA
Interferon and Apoptosis in Host Defense

Sunday, March 28 | 5:00PM - 7:00PM
Challenges of the Intracellular Lifestyle
Room: Rio Grande A-B

Speaker 3 of 4
* John C. Boothroyd, Stanford University School of Medicine, USA
Toxoplasma Gondii Persistence

Sunday, March 28 | 5:00PM - 7:00PM
Challenges of the Intracellular Lifestyle
Room: Rio Grande A-B

Speaker 4 of 4
Kathy DeRiemer, University of California, Davis, USA
Short Talk: Latency in Mycobacterium tuberculosis: Epidemiological Evidence for the Role of a Specific Regulon

Sunday, March 28 | 5:00PM - 7:00PM
Cancer Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 3
* Peter Hersey, University of Newcastle, Australia
How Human Melanoma Cells Evade TRAIL Induced Apoptosis


Sunday, March 28 | 5:00PM - 7:00PM
Cancer Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 3
Federico Garrido, Hospital Universitario Virgen de las Nieves, Spain
MHC Antigens and Tumor Immune Escape


Sunday, March 28 | 5:00PM - 7:00PM
Cancer Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 3 of 3
Soldano Ferrone, University of Pittsburgh, USA
HLA Antigens and Tumor Cell Immunoescape


Sunday, March 28 | 7:00PM - 8:00PM
Social Hour
Room: Bataan


Sunday, March 28 | 7:30PM - 10:00PM
Poster Session 3
Room: Bataan


Monday, March 29 | 7:00AM - 8:00AM
Breakfast
Room: Rio Grande A-C


Monday, March 29 | 8:00AM - 11:15AM
Cancer Due to Persistent Infections (Joint)
Room: Bataan

Speaker 1 of 6
Robert W. Tindle, Royal Children's Hospital, Australia
Immune Evasion in Human Papillomavirus-Associated Cervical Carcinoma

Monday, March 29 | 8:00AM - 11:15AM
Cancer Due to Persistent Infections (Joint)
Room: Bataan

Speaker 2 of 6
Timothy L. Cover, Vanderbilt University School of Medicine, USA
Helicobacter pylori: Virulence Factors and Cancer

Monday, March 29 | 8:00AM - 11:15AM
Cancer Due to Persistent Infections (Joint)
Room: Bataan

Speaker 3 of 6
Laimonis A. Laimins, Northwestern University, USA
The Differentiation-Dependent Life Cycle of Human Papillomaviruses

Monday, March 29 | 8:00AM - 11:15AM
Cancer Due to Persistent Infections (Joint)
Room: Bataan

Speaker 4 of 6
* Yuan Chang, University of Pittsburgh Cancer Institute, USA
Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Immunoevasion and Tumorigenesis: Two Sides of the Same Coin?

Monday, March 29 | 8:00AM - 11:15AM
Cancer Due to Persistent Infections (Joint)
Room: Bataan

Speaker 5 of 6
Rosemary Rochford, Upstate Medical University, State University of New York, USA
Short Talk: Holoendemic Malaria Alters Epstein-Barr Virus Persistence in Children

Monday, March 29 | 8:00AM - 11:15AM
Cancer Due to Persistent Infections (Joint)
Room: Bataan

Speaker 6 of 6
Sonja M. Best, NIAID, National Institutes of Health, USA
Short Talk: A Role for Caspases in Mediating Persistent Viral Infections?

Monday, March 29 | 9:20AM - 9:40AM
Coffee Break
Room: Rio Grande A-C


Monday, March 29 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Bataan


Monday, March 29 | 5:00PM - 7:00PM
Quiescence and Latency
Room: Rio Grande A-B

Speaker 1 of 3
Jerome A. Zack, University of California, Los Angeles, USA
Characterization and Elimination of Latent HIV

Monday, March 29 | 5:00PM - 7:00PM
Quiescence and Latency
Room: Rio Grande A-B

Speaker 2 of 3
Clifton E. Barry III, NIAID, National Institutes of Health, USA
The role of latent organisms in active TB: targeting cellular energy metabolism in the absence of replication with nitroimidazoles

Monday, March 29 | 5:00PM - 7:00PM
Quiescence and Latency
Room: Rio Grande A-B

Speaker 3 of 3
* Samuel H. Speck, Emory University, USA
Murine gammaherpesvirus 68 Persistence via Manipulation of B Cell Development

Monday, March 29 | 5:00PM - 7:00PM
Alternative Mechanisms of Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 1 of 4
Vincenzo Bronte, University of Verona, Italy
L-Arginine Catabolism in Myeloid Suppressor Cells as a Tool to Restrain T Cell Response


Monday, March 29 | 5:00PM - 7:00PM
Alternative Mechanisms of Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 2 of 4
Andrew L. Mellor, Georgia Regents University, USA
Tolerance by Tryptophan Catabolism


Monday, March 29 | 5:00PM - 7:00PM
Alternative Mechanisms of Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 3 of 4
* Jay A. Berzofsky, NCI, National Institutes of Health, USA
NKT Cell Mediated Suppression of Immunosurveillance through IL-13, Myeloid Cells, and TGF-beta


Monday, March 29 | 5:00PM - 7:00PM
Alternative Mechanisms of Immunoevasion
This session is from Immune Evasion
Room: Rio Grande C-D

Speaker 4 of 4
Paulo C. Rodriguez, Louisiana State University Health Sciences Center, USA
Short Talk: Arginase I Production by Tumor Associated Myeloid Cells Down-Regulates CD3z Chain and Block Specific T Cell Responses


Monday, March 29 | 7:00PM - 8:00PM
Social Hour
Room: Bataan


Monday, March 29 | 8:00PM - 11:00PM
Entertainment
Room: Bataan


Monday, March 29 | 8:00PM - 11:00PM
Cash Bar
Room: Bataan


Tuesday, March 30 | 10:26AM - 10:26AM
Departure


*Session Chair.