Web Desc
Mechanisms of DNA Replication and Recombination
Organizer(s): Stephen P. Bell and Roland Kanaar
Date: January 05 - 11, 2005
Location: Keystone Resort, Keystone, CO, USA
Supported by The Director's Fund
For important information on the coronavirus, please click here
Summary of Meeting:
The Keystone Symposium on DNA Replication and Recombination is the only meeting of its type that draws large numbers of participants from both fields. The meeting has been designed to have a comprehensive coverage of the central aspects of both fields, including the traditional studies of biochemical mechanisms, how structural biology is informing our understanding of molecular function, and how biochemical mechanisms are expanding our understanding of biological function. Recent studies make it clear that the stability of the genome relies upon coordinated function of these two events, particularly at the DNA replication fork. This meeting provides a special opportunity for people working in replication and recombination to benefit from a comprehensive view, spanning complex biological concepts to atomic detail. The fact that the meeting is 'open' ensures maximum exposure and accessibility for speakers and participants. The inclusion of workshops provides the opportunity for more junior members of the field (including graduate students and postdocs) to present their work and to explore work being performed in the broader field. Finally, the diversity of topics covered by this meeting exposes the participants to a broader spectrum of ideas, techniques and results than the more focused meetings we normally attend. Past meetings have facilitated important interactions between the replication and recombination fields and we anticipate that this will continue. The last meeting of this type was held in January 2002 and the many significant developments in the intervening time will make this a timely and exciting meeting.
Discounted Abstract Deadline: September 15 2004
Discounted Registration Deadline: November 5 2004
We have reached maximum abstract capacity for this meeting.


We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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Program

Wednesday, January 05 | 3:00PM - 7:30PM
Registration
Room: Columbine Foyer


Wednesday, January 05 | 6:30PM - 7:30PM
Refreshments
Room: Longs Foyer


Wednesday, January 05 | 7:30PM - 8:30PM
Keynote Address
Room: Longs/Quandary

Speaker 1 of 1
James E. Haber, Brandeis University, USA
Multiple Recombination and Replication Mechanisms to Repair a Broken Chromosome

Thursday, January 06 | 7:00AM - 8:00AM
Breakfast
Room: Grays


Thursday, January 06 | 8:00AM - 11:00AM
Mechanisms of Recombination
Room: Longs/Quandary

Speaker 1 of 5
* Stephen C. Kowalczykowski, University of California, Davis, USA
Visualization of Recombination at the Single-Molecule Level

Thursday, January 06 | 8:00AM - 11:00AM
Mechanisms of Recombination
Room: Longs/Quandary

Speaker 2 of 5
Michael M. Cox, University of Wisconsin-Madison, USA
Short Talk: Genome Reconstitution after Extensive DNA Damage in Deinococcus radiodurans

Thursday, January 06 | 8:00AM - 11:00AM
Mechanisms of Recombination
Room: Longs/Quandary

Speaker 3 of 5
Phoebe A. Rice, University of Chicago, USA
Structure of a Rad51 Filament

Thursday, January 06 | 8:00AM - 11:00AM
Mechanisms of Recombination
Room: Longs/Quandary

Speaker 4 of 5
Stephen C. West, Francis Crick Institute, UK
Double Strand Break Repair by Homologous Recombination

Thursday, January 06 | 8:00AM - 11:00AM
Mechanisms of Recombination
Room: Longs/Quandary

Speaker 5 of 5
Roland Kanaar, Erasmus MC, Netherlands
Dynamics of Genome Maintenance Processes

Thursday, January 06 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Foyer


Thursday, January 06 | 11:00AM - 1:00PM
Poster Setup
Room: Grays


Thursday, January 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays


Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 1 of 7
* Oscar Aparicio, University of Southern California, USA
Mrc1 is Required for Normal Progression of Replication Forks throughout Chromatin in Saccharomyces cerevisiae

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 2 of 7
Chrystelle Maric Antoinat, Institut Andre Lwoff, France
Structure and Distribution of Joint DNA Molecules during the Naturally
Synchronous S Phase in Physarum polycephalum


Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 3 of 7
Peter W. Lewis, University of Wisconsin-Madison, USA
Regulation of DNA Replication and Transcription by the Drosophila Myb Complex

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 4 of 7
Brian R. Calvi, Indiana University, USA
Humpty Dumpty Defines a New Gene Family Required for DNA Amplification and Cell Proliferation

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 5 of 7
Marie-Francoise Noirot-Gros, Institut National de la Recherche Agronomique, France
YabA, A Novel Initiation Regulator in Gram-Positive Bacteria

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 6 of 7
Jue D. Wang, Massachusetts Institute of Technology, USA
Nutritional Control of Replication Elongation

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 1: Regulation of DNA Replication
Room: Longs

Speaker 7 of 7
Kai Stoeber, University College London, UK
HPV E4 Protein Inhibits DNA Replication by Blocking Pre-RC Assembly

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 1 of 7
* Wolf-Dietrich Heyer, University of California, Davis, USA
Activation of Recombinational DNA Repair by DNA Damage Checkpoint-Mediated Phosphorylation of Rad55 Protein

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 2 of 7
Cindy W. Fung, Columbia University, USA
The Role of the Rad51 ATPase in Homologous Recombination

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 3 of 7
Alexander V. Mazin, Drexel University College of Medicine, USA
The Role of Ca2+ in Activation of Human Homologous Recombination Proteins

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 4 of 7
Piero R. Bianco, University at Buffalo, State University of New York, USA
Single Molecule Studies of the Human Rad54 Protein Reveal Insight into the Mechanism of Stimulation of DNA Strand Exchange

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 5 of 7
Francesca Storici, Georgia Institute of Technology, USA
Mechanism of Double-Strand Break Repair by Single-Strand Oligonucleotides in Yeast

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 6 of 7
Matthew Porteus, Stanford University School of Medicine, USA
The Use of Zinc Finger Nuclease to Manipulate the Genome of Human Somatic Cells in a Site-Specific Fashion

Thursday, January 06 | 2:00PM - 4:00PM
Workshop 2: DNA Recombination
Room: Quandary

Speaker 7 of 7
Jie Liu, University of California, Davis, USA
Dynamics of T4 Gene 32 Protein-ssDNA Interactions during Presynaptic Filament Assembly

Thursday, January 06 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Longs Foyer


Thursday, January 06 | 5:00PM - 7:00PM
Mechanisms of DNA Replication
Room: Longs/Quandary

Speaker 1 of 4
* Tom E. Ellenberger, Washington University School of Medicine, USA
The Anatomy of Infidelity: Lesion Bypass By Faithful and Promiscuous Polymerases

Thursday, January 06 | 5:00PM - 7:00PM
Mechanisms of DNA Replication
Room: Longs/Quandary

Speaker 2 of 4
Michael E. O'Donnell, Rockefeller University, USA
Clamp Loaders

Thursday, January 06 | 5:00PM - 7:00PM
Mechanisms of DNA Replication
Room: Longs/Quandary

Speaker 3 of 4
Anja-Katrin Bielinsky, University of Minnesota, USA
Short Talk: Mcm10 Controls the Stability and Chromatin Association of DNA Polymerase-alpha

Thursday, January 06 | 5:00PM - 7:00PM
Mechanisms of DNA Replication
Room: Longs/Quandary

Speaker 4 of 4
Haruhiko Takisawa, Osaka University Graduate School of Science, Japan
Protein Networks in the Assembly of the Eukaryotic Replication Fork in Xenopus Egg Extracts

Thursday, January 06 | 7:00PM - 8:00PM
Social Hour
Room: Grays


Thursday, January 06 | 7:30PM - 10:00PM
Poster Session 1
Room: Grays


Friday, January 07 | 7:00AM - 8:00AM
Breakfast
Room: Grays


Friday, January 07 | 8:00AM - 11:00AM
Genome Stability I
Room: Longs/Quandary

Speaker 1 of 5
* Tania A. Baker, Massachusetts Institute of Technology, USA
Transposition by Phage Mu


Friday, January 07 | 8:00AM - 11:00AM
Genome Stability I
Room: Longs/Quandary

Speaker 2 of 5
George Chaconas, University of Calgary, Canada
Short Talk: 3D Reconstruction of the Mu Transposase and the Type 1 Transpososome: A Structural Framework for Mu DNA Transposition

Friday, January 07 | 8:00AM - 11:00AM
Genome Stability I
Room: Longs/Quandary

Speaker 3 of 5
John F.X. Diffley, Francis Crick Institute, UK
DNA Replication Control and Genome Stability in Saccharomyces cerevisiae

Friday, January 07 | 8:00AM - 11:00AM
Genome Stability I
Room: Longs/Quandary

Speaker 4 of 5
Maria Jasin, Memorial Sloan Kettering Cancer Center, USA
Double-Strand Breaks and the Maintenance of Genomic Integrity

Friday, January 07 | 8:00AM - 11:00AM
Genome Stability I
Room: Longs/Quandary

Speaker 5 of 5
Vicki Lundblad, The Salk Institute for Biological Studies, USA
A Telomere-Specific RPA Mediates Replication and Repair at Chromosome Ends


Friday, January 07 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Foyer


Friday, January 07 | 11:00AM - 1:00PM
Poster Setup
Room: Grays


Friday, January 07 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays


Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 1 of 8
Ronald Chalmers, University of Nottingham Medical School, UK
Miniature Inverted-Repeat Transposable Elements (MITES) in Neisseria

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 2 of 8
Jeanne Marie DiChiara, University of Illinois at Urbana-Champaign, USA
The Integrase of Bacteroides Mobile Element CTnDOT Represents a Divergent Member of the Tyrosine Recombinase Family

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 3 of 8
Hiroshi Nakai, Georgetown University Medical Center, USA
The Mu Transpososome and Host Factors Promote Assembly of the Restart Primosome by a PriA-PriC-Dependent Pathway during Phage Mu Transposition

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 4 of 8
Graham F. Hatfull, University of Pittsburgh, USA
Site-Specific Recombination in the Mycobacterium Bxb1

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 5 of 8
Glenn Sanders, Replidyne, Inc., USA
General Priming in a Gram Positive Organism, B. subtilis

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 6 of 8
Marc S. Wold, University of Iowa, USA
Phosphorylation and Intersubunit Interactions Regulate Replication Protein A

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 7 of 8
Chiara Indiani, Rockefeller University, USA
Mechanism of DNA Polymerase Switching on a DNA Sliding Camp.

Friday, January 07 | 2:00PM - 4:00PM
Workshop 3: Mechanisms of Site-Specific Recombination and Re
plication
Room: Longs

Speaker 8 of 8
* Anca M. Segall, San Diego State University, USA
Control of Holliday Junction Resolution and Directionality by lambda Integrase

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 1 of 7
* Ian D. Hickson, University of Copenhagen, Denmark

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 2 of 7
Leonard Wu, Weatherall Institute of Molecular Medicine, UK
Resolution of Homologous Recombination Intermediates by the Bloom’s Syndrome Helicase

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 3 of 7
Marie-Agnès Petit, nstitut National de La Rescherche Agronomique (INRA), France
The UvrD Helicase, and Not the Rep Helicase, Dismantles RecA Nucleoprotein Filaments in Escherichia coli

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 4 of 7
Rebecca C. Burgess, National Cancer Institute, USA
Visualization of Srs2 Anti-Recombinase Activity in vivo

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 5 of 7
Steven Brill, Rutgers University, USA
Characterization of Slx5-Slx8, a Potential SUMO E3 Ligase in S. cerevisiae

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 6 of 7
Zoya Petrushenko, University of Oklahoma, USA
DNA Remodeling by E. coli Condensin MukBEF and its SMC Subunit MukB

Friday, January 07 | 2:00PM - 4:00PM
Workshop 4: Topoisomerases and Helicases
Room: Quandary

Speaker 7 of 7
Fekret Osman, University of Oxford, UK
Loss of the F-Box DNA Helicase, Fdh1, Promotes Rhp51-Dependent Recombination and Suppression of Genotoxin Sensitivity in Schizosaccharomyces pombe Cells Lacking Rad22

Friday, January 07 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Longs Foyer


Friday, January 07 | 5:00PM - 7:00PM
Chromosome Dynamics I
Room: Longs/Quandary

Speaker 1 of 3
* Virginia A. Zakian, Princeton University, USA
Processivity of Telomerase in Baker's Yeast

Friday, January 07 | 5:00PM - 7:00PM
Chromosome Dynamics I
Room: Longs/Quandary

Speaker 2 of 3
Bruce W. Stillman, Cold Spring Harbor Laboratory, USA
The Origin Recognition Complex: Involvement in DNA Replication, Chromosome Segregation and Cytokinesis

Friday, January 07 | 5:00PM - 7:00PM
Chromosome Dynamics I
Room: Longs/Quandary

Speaker 3 of 3
Frank Uhlmann, Cancer Research UK London Research Institute, UK
The Establishment of Sister Chromatid Cohesion during DNA Replication

Friday, January 07 | 7:00PM - 8:00PM
Social Hour
Room: Grays


Friday, January 07 | 7:30PM - 10:00PM
Poster Session 2
Room: Grays


Saturday, January 08 | 7:00AM - 8:00AM
Breakfast
Room: Grays


Saturday, January 08 | 8:00AM - 11:00AM
Initiation of DNA Replication
Room: Longs/Quandary

Speaker 1 of 5
* Anindya Dutta, University of Virginia, USA
Replication Initiation in Mammalian Cells

Saturday, January 08 | 8:00AM - 11:00AM
Initiation of DNA Replication
Room: Longs/Quandary

Speaker 2 of 5
Stephen P. Bell, Massachusetts Institute of Technology, USA
Origin Selection by ORC/Cdc6/MOM

Saturday, January 08 | 8:00AM - 11:00AM
Initiation of DNA Replication
Room: Longs/Quandary

Speaker 3 of 5
Nick Rhind, University of Massachusetts Medical School, USA
Short Talk: Origin Firing in S. pombe

Saturday, January 08 | 8:00AM - 11:00AM
Initiation of DNA Replication
Room: Longs/Quandary

Speaker 4 of 5
Johannes C. Walter, Harvard Medical School, USA
Degradation of Cd+1 in S Phase

Saturday, January 08 | 8:00AM - 11:00AM
Initiation of DNA Replication
Room: Longs/Quandary

Speaker 5 of 5
Stephen D. Bell, Indiana University, USA
Initiators, Origins and Primase in an Archaeon Sulfolobus solfataricus

Saturday, January 08 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Foyer


Saturday, January 08 | 11:00AM - 1:00PM
Poster Setup
Room: Grays


Saturday, January 08 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays


Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 1 of 8
* James M. Berger, Johns Hopkins University School of Medicine, USA

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 2 of 8
Jacob E. Corn, ETH in Zurich, Switzerland
Towards a Structural Description of Bacterial Priming

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 3 of 8
Scott Bailey, Yale University, USA
Structural Studies of the Prokaryotic Primosome

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 4 of 8
Satwik Kamtekar, Yale University, USA
Structural Studies of Protein Priming by phi 29 DNA Polymerase

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 5 of 8
Xiangpeng Kong, New York University, USA
Crystal Structure of E. coli RecR Protein and Structural-Functional Implications

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 6 of 8
Andrei L. Okorokov, University College London, UK
Molecular Structure of Human Geminin

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 7 of 8
Brian A. Learn, Johns Hopkins University, USA
Crystal Structure and Functional Analysis of the DNA-Binding Domain of the Bacteriophage lambda O Replication Initiator

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 5: Structural Studies of Replication and Recombina
tion
Room: Longs

Speaker 8 of 8
Stephen G. Anderson, University of Florida, USA
Temporal Correlation of ATP Hydrolysis-Dependent DNA and Sliding Clamp Release from the E. coli gamma Complex Clamp Loader

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 1 of 7
Matthew J. Neale, Memorial Sloan-Kettering Cancer Center, USA
A Novel Pathway for Removal of Spo11 from Meiotic DNA Double-strand Break Ends

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 2 of 7
Hiroyuki Oshiumi, Hokkaido University, Japan
Regulation of Crossover Formation by a Cdk Kinase, Cdc28, During Meiosis

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 3 of 7
Christina M. Bradley, NIDDK, National Institutes of Health, USA
Structural Basis for DNA Compaction by Barrier to Autointegration Factor (BAF)

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 4 of 7
* Michael J. Lichten, National Cancer Institute, National Institutes of Health, USA
Responding to DNA Double-Strand Breaks: Interplay with Chromosome Structure

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 5 of 7
Takehiko Kobayashi, National Institute for Basic Biology, Japan
Mechanisms to Keep the Stability of the Ribosomal RNA Gene Cluster in Yeast

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 6 of 7
Luis F. Aragón, MRC Clinical Sciences Centre, UK
Structural Maintenance of Chromosomes Genes SMC5 and SMC6 are Required for the Correct Segregation of Repetitive Regions

Saturday, January 08 | 2:00PM - 4:00PM
Workshop 6: Meiosis and Chromesome Dynamics
Room: Quandary

Speaker 7 of 7
Alexander V. Strunnikov, Guangzhou Institute of Biomedicine and Health, China
Genome-Wide Analysis of Condensin Targeting to Chromatin during Cell Cycle Progression

Saturday, January 08 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Longs Foyer


Saturday, January 08 | 5:00PM - 7:00PM
Mechanism of Checkpoint Function
Room: Longs/Quandary

Speaker 1 of 4
* John H.J. Petrini, Memorial Sloan-Kettering Cancer Center, USA
Genetic Analysis of Chromosome Break Metabolism in Eukaryotic Cells

Saturday, January 08 | 5:00PM - 7:00PM
Mechanism of Checkpoint Function
Room: Longs/Quandary

Speaker 2 of 4
Susan M. Gasser, Friedrich Miescher Institute for Biomedical Research, Switzerland
Remodelling at Double-Strand Breaks and Stalled Fork Collapse

Saturday, January 08 | 5:00PM - 7:00PM
Mechanism of Checkpoint Function
Room: Longs/Quandary

Speaker 3 of 4
Hitoshi Kurumizaka, Waseda University, Japan
Short Talk: Structural and Functional Analyses of the Human Homologous-Pairing Protein, Dmc1

Saturday, January 08 | 5:00PM - 7:00PM
Mechanism of Checkpoint Function
Room: Longs/Quandary

Speaker 4 of 4
Marco F. Foiani, Instituto FIRC di Oncologia Molecolare, Italy
Replication Fork-Dependent Checkpoint Signaling

Saturday, January 08 | 7:00PM - 8:00PM
Social Hour
Room: Grays


Saturday, January 08 | 7:30PM - 10:00PM
Poster Session 3
Room: Grays


Sunday, January 09 | 7:00AM - 8:00AM
Breakfast
Room: Grays


Sunday, January 09 | 8:00AM - 11:00AM
Interplay between Replication and Recombination
Room: Longs/Quandary

Speaker 1 of 5
* Dale B. Wigley, Institute of Cancer Research, UK
Structure and Mechanism of RecBCD

Sunday, January 09 | 8:00AM - 11:00AM
Interplay between Replication and Recombination
Room: Longs/Quandary

Speaker 2 of 5
Susan T. Lovett, Brandeis University, USA
Template Switch Replication Fork Repair

Sunday, January 09 | 8:00AM - 11:00AM
Interplay between Replication and Recombination
Room: Longs/Quandary

Speaker 3 of 5
Nancy L. Craig, Johns Hopkins University School of Medicine, USA
The hAT Transposase Hermes is a RAG-Like Transposase

Sunday, January 09 | 8:00AM - 11:00AM
Interplay between Replication and Recombination
Room: Longs/Quandary

Speaker 4 of 5
Bénédicte Michel, Institut National de la Recherche Agronomique, France
Replication Fork Reversal at Stalled Forks

Sunday, January 09 | 8:00AM - 11:00AM
Interplay between Replication and Recombination
Room: Longs/Quandary

Speaker 5 of 5
Richard D. Kolodner, Ludwig Institute for Cancer Research, USA
Identification of Pathways that Prevent Genome Instability

Sunday, January 09 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Foyer


Sunday, January 09 | 11:00AM - 1:00PM
Poster Setup
Room: Grays


Sunday, January 09 | 1:00PM - 10:00PM
Poster Viewing
Room: Grays


Sunday, January 09 | 2:00PM - 4:00PM
Workshop 7: Telomeres and Checkpoints
Room: Longs

Speaker 1 of 6
* Kathleen Collins, University of California, Berkeley, USA
Assembly and Activity of Telomerase Holoenzyme

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 7: Telomeres and Checkpoints
Room: Longs

Speaker 2 of 6
Tara J. Moriarty, Lady Davis Institute for Medical Research, Canada
The Human Telomerase Accessory Domain Prevents Incorporation of Non-telomeric DNA Sequences and Regulates DNA Elongation in a Substrate Length- and Sequence-dependent Fashion

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 7: Telomeres and Checkpoints
Room: Longs

Speaker 3 of 6
Eric A. Hendrickson, University of Minnesota Medical School, USA
DNA-PK Regulates Telomere Length and Genomic Stability in Human Somatic Cells

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 7: Telomeres and Checkpoints
Room: Longs

Speaker 4 of 6
Mark Meuth, University of Sheffield, UK
A Mutant Allele of MRE11 that Suppresses ATM-mediated Signaling and Homologous Recombination Repair Induced by Thymidine

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 7: Telomeres and Checkpoints
Room: Longs

Speaker 5 of 6
Serge Gangloff, CEA de Fontenay-aux-Roses, France
Spontaneous Mitotic Crossovers are Negatively Controlled by DNA Damage Checkpoint Proteins

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 7: Telomeres and Checkpoints
Room: Longs

Speaker 6 of 6
Robert A. Sclafani, University of Colorado Denver, USA
Cdc7/Dbf4 and Rad53 Kinases Regulate DNA Replication

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 8: DNA Repair
Room: Quandary

Speaker 1 of 6
* Tanya T. Paull, University of Texas at Austin, USA
Mre11/Rad50/Nbs1 (M/R/N) Interactions with DNA Initiate the ATM Kinase Signaling Response

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 8: DNA Repair
Room: Quandary

Speaker 2 of 6
Bernard S. Lopez, Institut Gustave Roussy, France
Genome Rearrangements Induced by Double Strand Breaks and NHEJ In Mammalian Cells

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 8: DNA Repair
Room: Quandary

Speaker 3 of 6
Sang Eun Lee, University of Texas Health Science Center, USA
Yeast Chromatin Remodeler RSC Complex Facilitates End Joining Repair of DNA Double-Strand Break

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 8: DNA Repair
Room: Quandary

Speaker 4 of 6
Beth A. Tamburini, University of Colorado Denver Anchutz Medical Campus, USA
Histone Acetylation and Deacetylation during Double-Strand DNA Repair

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 8: DNA Repair
Room: Quandary

Speaker 5 of 6
Stephane Marcand, Centre des Etudes Atomique, France
Mismatched Priming by DNA Polymerase Pol4 during Non-Homologous End-Joining

Sunday, January 09 | 2:00PM - 4:00PM
Workshop 8: DNA Repair
Room: Quandary

Speaker 6 of 6
Peter McGlynn, University of Aberdeen, UK
Replication in a Protein Rich Environment

Sunday, January 09 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Longs Foyer


Sunday, January 09 | 5:00PM - 7:00PM
Genome Stability II
Room: Longs/Quandary

Speaker 1 of 5
* Jean J. Gautier, Columbia University, College of Physicians and Surgeons, USA

Sunday, January 09 | 5:00PM - 7:00PM
Genome Stability II
Room: Longs/Quandary

Speaker 2 of 5
Ryan C. Heller, Sloan-Kettering Institute, USA
and

Sunday, January 09 | 5:00PM - 7:00PM
Genome Stability II
Room: Longs/Quandary

Speaker 3 of 5
* Kenneth J. Marians, Memorial Sloan Kettering Cancer Center, USA
Multiple Pathways of Replisome Loading During Replication Fork Restart

Sunday, January 09 | 5:00PM - 7:00PM
Genome Stability II
Room: Longs/Quandary

Speaker 4 of 5
Thomas A. Kunkel, NIEHS, National Institutes of Health, USA
Enzymatic Switching for Efficient and Accurate Translesion DNA Replication

Sunday, January 09 | 5:00PM - 7:00PM
Genome Stability II
Room: Longs/Quandary

Speaker 5 of 5
Kiyoshi Mizuuchi, NIDDK, National Institutes of Health, USA
Short Talk: Control of Transposase Activity within a Transpososome by the Configuration of the Flanking DNA Segment of the Transposon

Sunday, January 09 | 7:00PM - 8:00PM
Social Hour
Room: Grays


Sunday, January 09 | 7:30PM - 10:00PM
Poster Session 4
Room: Grays


Monday, January 10 | 7:00AM - 8:00AM
Breakfast
Room: Grays


Monday, January 10 | 8:00AM - 11:00AM
Chromosome Dynamics II
Room: Longs/Quandary

Speaker 1 of 4
Oren Levy, University of California, Berkeley, USA
Giant Proteins that Bully DNA

Monday, January 10 | 8:00AM - 11:00AM
Chromosome Dynamics II
Room: Longs/Quandary

Speaker 2 of 4
Douglas E. Koshland, Carnegie Institution of Washington, USA
Cohesins and Condensins: Lord of the Rings or Not?


Monday, January 10 | 8:00AM - 11:00AM
Chromosome Dynamics II
Room: Longs/Quandary

Speaker 3 of 4
David J. Sherratt, University of Oxford, UK
Short Talk: E. coli Chromosome Replication and Segregation

Monday, January 10 | 8:00AM - 11:00AM
Chromosome Dynamics II
Room: Longs/Quandary

Speaker 4 of 4
Galina V. Petukhova, National Institutes of Health, USA
Short Talk: The Interplay Between Hop2/Mnd1 and Rad51/Dmc1 Proteins in Meiotic Recombination

Monday, January 10 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Foyer


Monday, January 10 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Longs Foyer


Monday, January 10 | 5:00PM - 7:30PM
Recombination and DNA Repair
Room: Longs/Quandary

Speaker 1 of 5
Jean J. Gautier, Columbia University, College of Physicians and Surgeons, USA
Regulation of Initiation of DNA Replication

Monday, January 10 | 5:00PM - 7:30PM
Recombination and DNA Repair
Room: Longs/Quandary

Speaker 2 of 5
Wei Yang, NIDDK, National Institutes of Health, USA
Portraints of a Y-Family DNA Polymerase

Monday, January 10 | 5:00PM - 7:30PM
Recombination and DNA Repair
Room: Longs/Quandary

Speaker 3 of 5
Jac A. Nickoloff, Colorado State University, USA
Short Talk: Sgs1 Regulation of Gene Conversion Tract Lengths and Crossovers is Independent of ATP Hydrolysis

Monday, January 10 | 5:00PM - 7:30PM
Recombination and DNA Repair
Room: Longs/Quandary

Speaker 4 of 5
Matthew D. Weitzman, Children's Hospital of Philadelphia, USA
Interactions of Viruses with the Cellular Replication and Repair Machinery

Monday, January 10 | 5:00PM - 7:30PM
Recombination and DNA Repair
Room: Longs/Quandary

Speaker 5 of 5
* Rodney J. Rothstein, Columbia University Medical Center, USA
Choreography of the DNA Damage Response in Budding Yeast

Monday, January 10 | 7:30PM - 8:30PM
Social Hour
Room: Grays


Monday, January 10 | 8:30PM - 11:30PM
Entertainment
Room: Grays


Monday, January 10 | 8:30PM - 11:30PM
Cash Bar
Room: Grays


Tuesday, January 11 | 10:21AM - 10:21AM
Departure


*Session Chair
†Invited, not yet responded.