Web Desc
Frontiers of NMR in Molecular Biology IX
Organizer(s): Brian D. Sykes, Juli Feigon and James H. Prestegard
Date: January 29 - February 04, 2005
Location: Banff Centre, Banff, AB, Canada
Supported by The Director's Fund
Summary of Meeting:
Nuclear Magnetic Resonance (NMR) has a long history of evolving to meet new challenges of molecular biology; this evolution will be even more rapid in a genomic and post-genomic era. Already the challenge of providing structures of proteins on a genomic scale has produced new NMR approaches for fast structure determination and the prospect of having more targets for the pharmaceutical industry has spawned new NMR based means of screening for molecular interactions. For the future, NMR is expanding into biologically and medically important areas such as integrated systems biology and metabonomics. There are new demands for working with large complex data sets. The realization that biological function often involves the interplay of groups of macromolecules in a dynamic setting demands new methods for monitoring macromolecular interaction in large systems as well as motion in these systems. The advances needed often come from discussions among scientists expert in solids NMR, macromolecular solution NMR, molecular biology and drug discovery. The ultimate challenge for the meeting will be to stimulate discussion among scientists representing these diverse fields. The meeting will be largely organized around new approaches to the challenges defined above and provide a forum for discussion among molecular biologists, NMR spectroscopists, computational biologists, and drug design specialists. The program will be organized around problem areas and integrate talks by scientists having different perspectives on their solution. Scheduled breaks between formal presentation sessions are ideal for simulating discussion among participants. Discussion of more practical aspects will be promoted by the addition of afternoon workshops having a tutorial structure.
Discounted Abstract Deadline: September 29 2004
Discounted Registration Deadline: November 30 2004
We gratefully acknowledge additional support for this conference from:

Bruker BioSpin Corp.

Cambridge Isotope Laboratories
Chenomx
ISOTEC, a member of the Sigma-Aldrich Group
Spectra Gases, Inc. Stable Isotopes GroupVarian, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Novartis Institutes for BioMedical Research
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of General Medical Sciences (NIGMS)
Grant No. 1R13-GM073374-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Saturday, January 29 | 3:00PM - 7:30PM
Registration
Room: Eric Harvie Foyer


Saturday, January 29 | 6:30PM - 7:30PM
Refreshments
Room: Eric Harvie Foyer


Saturday, January 29 | 7:30PM - 8:30PM
Keynote Address
Room: Eric Harvie Theatre

Speaker 1 of 1
Stephen W. Fesik, Vanderbilt University School of Medicine, USA
NMR as a Tool in Drug Research

Sunday, January 30 | 7:00AM - 8:00AM
Breakfast
Room: Donald Cameron Hall


Sunday, January 30 | 8:00AM - 11:00AM
NMR Studies of Membrane Proteins
Room: Eric Harvie Theatre

Speaker 1 of 6
* Robert G. Griffin, Massachusetts Institute of Technology, USA

Sunday, January 30 | 8:00AM - 11:00AM
NMR Studies of Membrane Proteins
Room: Eric Harvie Theatre

Speaker 2 of 6
Stanley J. Opella, University of California, San Diego, USA
New NMR Methods for Membrane Proteins

Sunday, January 30 | 8:00AM - 11:00AM
NMR Studies of Membrane Proteins
Room: Eric Harvie Theatre

Speaker 3 of 6
Lynmarie K. Thompson, University of Massachusetts, USA
Solid-State NMR Studies of Structure and Dynamics in Transmembrane Signaling

Sunday, January 30 | 8:00AM - 11:00AM
NMR Studies of Membrane Proteins
Room: Eric Harvie Theatre

Speaker 4 of 6
Mei Hong, Massachusetts Institute of Technology, USA
Structure and Folding of Membrane Peptides and Proteins

Sunday, January 30 | 8:00AM - 11:00AM
NMR Studies of Membrane Proteins
Room: Eric Harvie Theatre

Speaker 5 of 6
Tomasz Cierpicki, University of Michigan, USA
Short Talk: Measurement of Residual Dipolar Couplings and Refinement of the Structures of Membrane Proteins – Application to 50 kDa Complex of OmpA in DPC Micelles

Sunday, January 30 | 8:00AM - 11:00AM
NMR Studies of Membrane Proteins
Room: Eric Harvie Theatre

Speaker 6 of 6
Jianjun Wang, Wayne State University, USA
Short Talk: NMR Structural Studies of Human Apolipoprotein A-I and High-Density Lipoprotein Particles

Sunday, January 30 | 9:20AM - 9:40AM
Coffee Break
Room: Eric Harvie Foyer


Sunday, January 30 | 11:00AM - 1:00PM
Poster Setup
Room: 122, 124


Sunday, January 30 | 1:00PM - 10:00PM
Poster Viewing
Room: 122, 124


Sunday, January 30 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Eric Harvie Foyer


Sunday, January 30 | 5:00PM - 7:00PM
NMR in Integrated Systems Biology
Room: Eric Harvie Theatre

Speaker 1 of 5
* Iain D. Campbell, University of Oxford, UK

Sunday, January 30 | 5:00PM - 7:00PM
NMR in Integrated Systems Biology
Room: Eric Harvie Theatre

Speaker 2 of 5
Jeremy K. Nicholson, Imperial College London, UK
NMR Spectroscopic Approaches in Metabonomics and Global Systems Biology

Sunday, January 30 | 5:00PM - 7:00PM
NMR in Integrated Systems Biology
Room: Eric Harvie Theatre

Speaker 3 of 5
Dorothee Kern, Brandeis University, HHMI, USA
Dynamic Personality of an Enzyme Underlies Catalysis

Sunday, January 30 | 5:00PM - 7:00PM
NMR in Integrated Systems Biology
Room: Eric Harvie Theatre

Speaker 4 of 5
Michael D. Reily, Pfizer Global Research & Development, USA
Metabolic Profiling Using NMR Spectroscopy

Sunday, January 30 | 5:00PM - 7:00PM
NMR in Integrated Systems Biology
Room: Eric Harvie Theatre

Speaker 5 of 5
Ian A. Lewis, University of Wisconsin-Madison, USA
Short Talk: Automated Filtering of NMR Spectra: A New Tool for the Discovery of Metabolites Associated with Type 2 Diabetes

Sunday, January 30 | 7:00PM - 8:00PM
Social Hour
Room: 122,124


Sunday, January 30 | 7:30PM - 10:00PM
Poster Session 1
Room: 122, 124


Monday, January 31 | 7:00AM - 8:00AM
Breakfast
Room: Donald Cameron Hall


Monday, January 31 | 8:00AM - 11:00AM
Large Proteins and Large Protein Assemblies
Room: Eric Harvie Theatre

Speaker 1 of 6
* John L. Markley, University of Wisconsin-Madison, USA

Monday, January 31 | 8:00AM - 11:00AM
Large Proteins and Large Protein Assemblies
Room: Eric Harvie Theatre

Speaker 2 of 6
Gerhard Wagner, Harvard Medical School, USA
Protein-Protein Interactions and Their Inhibition

Monday, January 31 | 8:00AM - 11:00AM
Large Proteins and Large Protein Assemblies
Room: Eric Harvie Theatre

Speaker 3 of 6
Brian D. Sykes, University of Alberta, Canada
Calcium Regulatory Proteins: From Solution to Intact Muscle Fiber

Monday, January 31 | 8:00AM - 11:00AM
Large Proteins and Large Protein Assemblies
Room: Eric Harvie Theatre

Speaker 4 of 6
Iain D. Campbell, University of Oxford, UK
Multi-Domain Proteins at the Cell-Surface

Monday, January 31 | 8:00AM - 11:00AM
Large Proteins and Large Protein Assemblies
Room: Eric Harvie Theatre

Speaker 5 of 6
Mitsu Ikura, University of Toronto, Canada
Structure and Function of “Large' Transcription and Signaling Complexes

Monday, January 31 | 8:00AM - 11:00AM
Large Proteins and Large Protein Assemblies
Room: Eric Harvie Theatre

Speaker 6 of 6
Masatsune Kainosho, Nagoya University, Japan
Short Talk: SAIL Method: An Ultimate Stable-Isotope Assisted NMR Approach

Monday, January 31 | 9:20AM - 9:40AM
Coffee Break
Room: Eric Harvie Foyer


Monday, January 31 | 11:00AM - 1:00PM
Poster Setup
Room: 122, 124


Monday, January 31 | 1:00PM - 10:00PM
Poster Viewing
Room: 122, 124


Monday, January 31 | 3:00PM - 4:30PM
Workshop A: New Structural Information - RDC's and Paramagne
tic Distances
Room: Eric Harvie Theatre

Speaker 1 of 6
* Ad Bax, NIDDK, National Institutes of Health, USA

Monday, January 31 | 3:00PM - 4:30PM
Workshop A: New Structural Information - RDC's and Paramagne
tic Distances
Room: Eric Harvie Theatre

Speaker 2 of 6
Bernd Simon, European Molecular Biology Laboratory, Germany
A New Protocol to Orient Structural Domains Based on RDCs

Monday, January 31 | 3:00PM - 4:30PM
Workshop A: New Structural Information - RDC's and Paramagne
tic Distances
Room: Eric Harvie Theatre

Speaker 3 of 6
Kalle Gehring, McGill University, Canada
Measurement of Residual Dipolar Couplings in Spinning Oriented Media

Monday, January 31 | 3:00PM - 4:30PM
Workshop A: New Structural Information - RDC's and Paramagne
tic Distances
Room: Eric Harvie Theatre

Speaker 4 of 6
Paul B. Card, University of Texas Southwestern Medical Center, USA
Structural Insights of PAS Domain Dimerization Using Paramagnetic Spin Labeling

Monday, January 31 | 3:00PM - 4:30PM
Workshop A: New Structural Information - RDC's and Paramagne
tic Distances
Room: Eric Harvie Theatre

Speaker 5 of 6
Amanda S. Altieri, National Cancer Institute, Frederick, USA
New Insights into STAT Tetramerization Derived from the Solution Structure of the N-Terminal Domain of STAT4

Monday, January 31 | 3:00PM - 4:30PM
Workshop A: New Structural Information - RDC's and Paramagne
tic Distances
Room: Eric Harvie Theatre

Speaker 6 of 6
Andrew J. Benie, Novo Nordisk A/S, Denmark
Assigning an Isoform of the Hepatitis 3c Protease, Using a Novel Combination of Triple Resonance Experiments and Residual Dipolar Coupling Constants

Monday, January 31 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Eric Harvie Foyer


Monday, January 31 | 5:00PM - 7:00PM
Structural Genomics - New Experimental Approaches
Room: Eric Harvie Theatre

Speaker 1 of 5
* Peter E. Wright, The Scripps Research Institute, USA

Monday, January 31 | 5:00PM - 7:00PM
Structural Genomics - New Experimental Approaches
Room: Eric Harvie Theatre

Speaker 2 of 5
Gaetano Thomas Montelione, Rutgers University, USA
Structural Proteomics of Eukaryotic Protein Domain Families

Monday, January 31 | 5:00PM - 7:00PM
Structural Genomics - New Experimental Approaches
Room: Eric Harvie Theatre

Speaker 3 of 5
John L. Markley, University of Wisconsin-Madison, USA
Eukaryotic Structural Proteomics: The NMR Side of the Pipeline

Monday, January 31 | 5:00PM - 7:00PM
Structural Genomics - New Experimental Approaches
Room: Eric Harvie Theatre

Speaker 4 of 5
James H. Prestegard, University of Georgia, USA
Residual Dipolar Couplings: A Basis for Protein Structure Determination of Novel Proteins and Protein Complexes

Monday, January 31 | 5:00PM - 7:00PM
Structural Genomics - New Experimental Approaches
Room: Eric Harvie Theatre

Speaker 5 of 5
Keith L. Constantine, Bristol Myers Squibb Company, USA
Short Talk: Protein-Ligand NOE Matching: An Approach for High-Throughput Structure Determination of Protein-Ligand Complexes

Monday, January 31 | 7:00PM - 8:00PM
Social Hour
Room: 122,124


Monday, January 31 | 7:30PM - 10:00PM
Poster Session 2
Room: 122, 124


Tuesday, February 01 | 7:00AM - 8:00AM
Breakfast
Room: Donald Cameron Hall


Tuesday, February 01 | 8:00AM - 11:15AM
New Methods in NMR
Room: Eric Harvie Theatre

Speaker 1 of 6
* Lewis E. Kay, University of Toronto, Canada

Tuesday, February 01 | 8:00AM - 11:15AM
New Methods in NMR
Room: Eric Harvie Theatre

Speaker 2 of 6
Christian Griesinger, Max Planck Institute for Biophysical Chemistry, Germany
Biomolecular Dynamics Studied by Dipolar Couplings

Tuesday, February 01 | 8:00AM - 11:15AM
New Methods in NMR
Room: Eric Harvie Theatre

Speaker 3 of 6
Ad Bax, NIDDK, National Institutes of Health, USA
Weak Alignment Provides Unique Opportunities in NMR Studies of Biomolecules

Tuesday, February 01 | 8:00AM - 11:15AM
New Methods in NMR
Room: Eric Harvie Theatre

Speaker 4 of 6
Thomas Szyperski, SUNY at Buffalo, USA
GFT NMR Based Protein Structure Determination in High-Throughput

Tuesday, February 01 | 8:00AM - 11:15AM
New Methods in NMR
Room: Eric Harvie Theatre

Speaker 5 of 6
Lucio Frydman, Weizmann Institute of Science, Israel
Principles and Perspectives of sub-Second Multidimensional NMR Spectroscopy

Tuesday, February 01 | 8:00AM - 11:15AM
New Methods in NMR
Room: Eric Harvie Theatre

Speaker 6 of 6
Gerhard Wider, ETH Zurich, Switzerland
Solution NMR Studies of Membrane Protein Structure and Folding

Tuesday, February 01 | 9:20AM - 9:40AM
Coffee Break
Room: Eric Harvie Foyer


Tuesday, February 01 | 11:15AM - 1:00PM
Poster Setup
Room: 122, 124


Tuesday, February 01 | 1:00PM - 10:00PM
Poster Viewing
Room: 122, 124


Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 1 of 8
* Gerhard Wagner, Harvard Medical School, USA

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 2 of 8
Bernhard H. Geierstanger, Genomics Institute of the Novartis Research Foundation, USA
High-throughput Chemical Analysis, Compound Screening and Metabolite Measurements Using An Automated Micro-Coil Flow NMR System and Only Five Microliter of Sample

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 3 of 8
Gregg Siegal, ZoBio, Netherlands
Target Immobilized NMR Screening – An Efficient and Sensitive New Method for Ligand Discovery

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 4 of 8
Gordon S. Rule, Carnegie Mellon University, USA
PEPMORPH: Drug Discovery and Homology Detection Using Sparse NMR Data

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 5 of 8
Daniel F. Wyss, Merck Research Laboratories, USA
NMR-Based Screening Applied to Drug Discovery Targets

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 6 of 8
Maurizio Pellecchia, University of California, Riverside, USA
Targeting Apoptosis via Chemical Design: A NMR- and Structure-Based Approach

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 7 of 8
Eric C. Johnson, Bruker Biospin Corporation, USA
NMR Screening Efforts to Identify Inhibitors of the HIV Rev-RRE Interaction

Tuesday, February 01 | 3:00PM - 4:45PM
Workshop B: New Methods for Metabonomics and Drug Discovery
Room: Eric Harvie Theatre

Speaker 8 of 8
Carolyn M. Slupsky, USA
Metabolomic NMR Data Analysis in Human Disease

Tuesday, February 01 | 4:45PM - 5:00PM
Coffee & Snacks Available
Room: Eric Harvie Foyer


Tuesday, February 01 | 5:00PM - 7:00PM
Small Molecule-Macromolecule Interactions and Drug Design
Room: Eric Harvie Theatre

Speaker 1 of 4
* Michael D. Reily, Pfizer Global Research & Development, USA

Tuesday, February 01 | 5:00PM - 7:00PM
Small Molecule-Macromolecule Interactions and Drug Design
Room: Eric Harvie Theatre

Speaker 2 of 4
Bernd Meyer, University of Hamburg, Germany
STD-NMR: Binding of Ligands to Live Cells and GPCRs and as an Effective Tool to Design New Ligands

Tuesday, February 01 | 5:00PM - 7:00PM
Small Molecule-Macromolecule Interactions and Drug Design
Room: Eric Harvie Theatre

Speaker 3 of 4
Mark McCoy, Merck & Co., Inc., USA
Short Talk: NMR Methods in Drug Discovery

Tuesday, February 01 | 5:00PM - 7:00PM
Small Molecule-Macromolecule Interactions and Drug Design
Room: Eric Harvie Theatre

Speaker 4 of 4
Till Maurer, Boehringer Ingelheim Pharma, Germany
Short Talk: Towards Structural Information from STD NMR Spectroscopy

Tuesday, February 01 | 7:00PM - 8:00PM
Social Hour
Room: 122,124


Tuesday, February 01 | 7:30PM - 10:00PM
Poster Session 3
Room: 122, 124


Wednesday, February 02 | 7:00AM - 8:00AM
Breakfast
Room: Donald Cameron Hall


Wednesday, February 02 | 8:00AM - 11:00AM
Nucleic Acids and Protein-Nucleic Acid Complexes
Room: Eric Harvie Theatre

Speaker 1 of 6
* Juli Feigon, University of California, Los Angeles, USA

Wednesday, February 02 | 8:00AM - 11:00AM
Nucleic Acids and Protein-Nucleic Acid Complexes
Room: Eric Harvie Theatre

Speaker 2 of 6
Joseph D. Puglisi, Stanford University, USA
NMR Investigations of Large RNAs


Wednesday, February 02 | 8:00AM - 11:00AM
Nucleic Acids and Protein-Nucleic Acid Complexes
Room: Eric Harvie Theatre

Speaker 3 of 6
Gabriele L. Varani, University of Washington, USA
Telomerase RNP: Processivity Determinants and Assembly

Wednesday, February 02 | 8:00AM - 11:00AM
Nucleic Acids and Protein-Nucleic Acid Complexes
Room: Eric Harvie Theatre

Speaker 4 of 6
Juli Feigon, University of California, Los Angeles, USA
Structural and Functional Studies of Human Telomerase and Yeast RNase III

Wednesday, February 02 | 8:00AM - 11:00AM
Nucleic Acids and Protein-Nucleic Acid Complexes
Room: Eric Harvie Theatre

Speaker 5 of 6
Nancy L. Greenbaum, Hunter college of CUNY, USA
Structural Biology of Pre-mRNA Splicing

Wednesday, February 02 | 8:00AM - 11:00AM
Nucleic Acids and Protein-Nucleic Acid Complexes
Room: Eric Harvie Theatre

Speaker 6 of 6
Teresa Carlomagno, Universität Hannover, Germany
Short Talk: The Conformation of the 2-OH Group of RNA in Solution: Implications for RNA Structure Stabilization

Wednesday, February 02 | 9:20AM - 9:40AM
Coffee Break
Room: Eric Harvie Foyer


Wednesday, February 02 | 11:00AM - 1:00PM
Poster Setup
Room: 122,124


Wednesday, February 02 | 1:00PM - 10:00PM
Poster Viewing
Room: 122,124


Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 1 of 7
* Stanley J. Opella, University of California, San Diego, USA

Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 2 of 7
Francesca M. Marassi, Sanford-Burnham Medical Research Institute, USA
Ion Transport and Apoptosis Regulatory Proteins in Lipid Environments.

Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 3 of 7
Anna A. De Angelis, University of California, San Diego, USA
High-Resolution NMR Spectroscopy of Membrane Proteins in Bicelles

Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 4 of 7
Charles R. Sanders, Vanderbilt University School of Medicine, USA
Assessing the General Feasibility of Solution NMR-Based Structural Determination for Polytopic Membrane Proteins

Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 5 of 7
Cheryl A. Hawkins, National Institutes of Health, USA
Structure of Saposin C in a Membrane-Mimicking Environment

Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 6 of 7
Philip L. Yeagle, University of Connecticut, USA
Membrane Protein Domain Behavior Suggests Folding Paradigms

Wednesday, February 02 | 3:00PM - 4:30PM
Workshop C: NMR Approaches and Applications for Membrane Pro
teins
Room: Eric Harvie Theatre

Speaker 7 of 7
Jin-Hong Chen, Memorial Sloan-Kettering Cancer Center, USA
Direct Observation of Membrane Lipid Hydration

Wednesday, February 02 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Eric Harvie Foyer


Wednesday, February 02 | 5:00PM - 7:00PM
Solid-State NMR
Room: Eric Harvie Theatre

Speaker 1 of 5
* Lynmarie K. Thompson, University of Massachusetts, USA

Wednesday, February 02 | 5:00PM - 7:00PM
Solid-State NMR
Room: Eric Harvie Theatre

Speaker 2 of 5
Robert G. Griffin, Massachusetts Institute of Technology, USA
Amyloid and Membrane Protein Structure Determination with Dipolar Recoupling and Dynamic Nuclear Polarization

Wednesday, February 02 | 5:00PM - 7:00PM
Solid-State NMR
Room: Eric Harvie Theatre

Speaker 3 of 5
Hartmut Oschkinat, FMP Berlin, Germany
Structure Determination of Proteins by Magic-Angle Spinning Solid-State NMR

Wednesday, February 02 | 5:00PM - 7:00PM
Solid-State NMR
Room: Eric Harvie Theatre

Speaker 4 of 5
Robert Tycko, NIDDK, National Institutes of Health, USA
Amyloid Fibrils and Protein Folding Intermediates: Solid State NMR Methods and Results

Wednesday, February 02 | 5:00PM - 7:00PM
Solid-State NMR
Room: Eric Harvie Theatre

Speaker 5 of 5
Klaus Gawrisch, NIAAA, National Institutes of Health, USA
Short Talk: NMR Studies on Single Lipid Bilayers Supported in Cylindrical Aluminum Oxide Nanopores – Reconstitution of GPCR

Wednesday, February 02 | 7:00PM - 8:00PM
Social Hour
Room: 122,124


Wednesday, February 02 | 7:30PM - 10:00PM
Poster Session 4
Room: 122, 124


Thursday, February 03 | 7:00AM - 8:30AM
Breakfast
Room: Donald Cameron Hall


Thursday, February 03 | 8:00AM - 11:00AM
Motions in Proteins and Nucleic Acids
Room: Eric Harvie Theatre

Speaker 1 of 6
* Christian Griesinger, Max Planck Institute for Biophysical Chemistry, Germany

Thursday, February 03 | 8:00AM - 11:00AM
Motions in Proteins and Nucleic Acids
Room: Eric Harvie Theatre

Speaker 2 of 6
Erik R. P. Zuiderweg, University of Michigan, USA
The Allostery of Hsp70 Chaperones Sstudied by NMR

Thursday, February 03 | 8:00AM - 11:00AM
Motions in Proteins and Nucleic Acids
Room: Eric Harvie Theatre

Speaker 3 of 6
A. Joshua Wand, University of Pennsylvania, USA
Protein Dynamics and Thermodynamics: A View Emerging from NMR Relaxation

Thursday, February 03 | 8:00AM - 11:00AM
Motions in Proteins and Nucleic Acids
Room: Eric Harvie Theatre

Speaker 4 of 6
Wolfgang Jahnke, Novartis Institutes for BioMedical Research, Switzerland
New Methods and Applications of NMR in Drug Discovery


Thursday, February 03 | 8:00AM - 11:00AM
Motions in Proteins and Nucleic Acids
Room: Eric Harvie Theatre

Speaker 5 of 6
Lewis E. Kay, University of Toronto, Canada
Solution NMR of High Molecular Weight Proteins

Thursday, February 03 | 8:00AM - 11:00AM
Motions in Proteins and Nucleic Acids
Room: Eric Harvie Theatre

Speaker 6 of 6
Arthur G. Palmer, III, Columbia University, USA
Protein Motions in Catalysis, Binding, and Folding

Thursday, February 03 | 9:20AM - 9:40AM
Coffee Break
Room: Eric Harvie Foyer


Thursday, February 03 | 4:30PM - 5:00PM
Coffee & Snacks Available
Room: Eric Harvie Foyer


Thursday, February 03 | 5:00PM - 7:00PM
Protein Folding and Disease
Room: Eric Harvie Theatre

Speaker 1 of 5
* James H. Prestegard, University of Georgia, USA

Thursday, February 03 | 5:00PM - 7:00PM
Protein Folding and Disease
Room: Eric Harvie Theatre

Speaker 2 of 5
Peter E. Wright, The Scripps Research Institute, USA
Functionally Disordered Proteins: A New Challenge in Structural Biology

Thursday, February 03 | 5:00PM - 7:00PM
Protein Folding and Disease
Room: Eric Harvie Theatre

Speaker 3 of 5
Christopher M. Dobson, University of Cambridge, UK
NMR Spectroscopy in Studies of Protein Folding and Misfolding

Thursday, February 03 | 5:00PM - 7:00PM
Protein Folding and Disease
Room: Eric Harvie Theatre

Speaker 4 of 5
Richard Dixon, University of North Carolina, Chapel Hill, USA
Short Talk: New Insights into FAK Signaling Based on Detection of a FAT Domain Folding Intermediate

Thursday, February 03 | 5:00PM - 7:00PM
Protein Folding and Disease
Room: Eric Harvie Theatre

Speaker 5 of 5
Markus Zweckstetter, Max-Planck Institute for Biophysical Chemistry / DZNE, Germany
Short Talk: Staying Dr. Jeckle: Residual Structure and Slow Dynamics in alpha-Synuclein

Thursday, February 03 | 8:00PM - 9:00PM
Social Hour
Room: Donald Cameron Hall


Thursday, February 03 | 8:00PM - 11:00PM
Entertainment
Room: Donald Cameron Hall


Thursday, February 03 | 9:00PM - 11:00PM
Cash Bar
Room: Donald Cameron Hall


Friday, February 04 | 10:26AM - 10:26AM
Departure


*Session Chair.