Cytokines, Disease and Therapeutic Intervention

Organizer(s): John J. O'Shea, Robert Kastelein and Mary Collins

Sponsored by Lilly Research Laboratories and The Director's Fund

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Summary of Meeting:

With the completion of the human genome project, we will shortly know all of the cytokines encoded within our genome. Indeed within the last few years, there have been reports of at least ten new cytokines. While this will provide us with our 'deck of cards', it is also clear that surprises continue to emerge regarding the function of cytokines we thought we knew well. Therefore, a major remaining problem is the understanding of the in vivo role of all these cytokines. Our comprehension of how cytokines work in concert in the protection against pathogens and in the pathogenesis of immune-mediated disease remains limited. Furthermore, the role of cytokines in immune homeostasis, lymphocyte memory and peripheral tolerance are actively being investigated. Equally exciting is the emergence of new cytokine and anti-cytokine therapies that have been remarkably effective. Our goals in this meeting are to review information on the newest cytokines, to provide new insights on their function in host defense and disease pathogenesis, to discuss new findings related to cytokine signaling and structure and to present the latest information on how manipulation of cytokines can be used therapeutically.

Discounted Abstract Deadline: October 12 2004

Discounted Registration Deadline: December 13 2004

Late Abstracts

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Abbott Bioresearch Center

Biogen Idec

DNAX Research Institute

Educational donation provided by Amgen

Genentech, Inc.

Wyeth Research Labs

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13-AI063645-01

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