Lymphocyte Activation and Signaling

Organizer(s): Susan K. Pierce, Gary A. Koretzky, Pamela L. Schwartzberg and Jason G. Cyster

Supported by The Director's Fund

Summary of Meeting:

The cells of the immune system are armed with a dizzying array of signaling receptors requiring them to integrate an enormous amount of information about their environment to mount the appropriate biologic response. Over the last several years much has been learned about the biochemical nature of the signaling cascades initiated by interactions of individual receptors with their ligands. This progress presents an exciting new challenge, namely, to understand how multiple signals are integrated in the context of the entire cell to bring about the ultimate cellular response. We propose to bring together distinguished scientists working at the cutting edge of immune cell signaling to describe their new findings and to address how these issues relate to human disease. This meeting will provide a view of 1) how the initial encounter of immune cell signaling receptors with their ligands ultimately leads to the biological response, be it activation, differentiation, movement, or cell death and 2) how this knowledge is being translated to important clinical problems in autoimmunity, immunodeficiency, vaccines, tumor immunity, transplantation and infectious diseases.

Scholarship Deadline: September 13 2005

Discounted Abstract Deadline: September 13 2005

Abstract Deadline: October 5 2005

Discounted Registration Deadline: November 7 2005

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13 AI068311-01

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