Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Understanding the Function of Human Genome Variation (2016K1)
Complex Traits: Genomics and Computational Approaches (2012B5)
Complex Traits: Biologic and Therapeutic Insights (2008C4)

Web Desc
Genome Sequence Variation and the Inherited Basis of Common Disease and Complex Traits Organizer(s): David M. Altshuler, Peter Donnelly and Trudy F.C. MacKay Date: January 08 - 13, 2006 Location: Big Sky Resort, Big Sky, MT, USA Supported by The Director's Fund For important information on the coronavirus, please click here Summary of Meeting: Common human diseases and most other traits vary in a continuous manner, modified by multiple genes and environmental influences. Rapidly expanding information about genome sequence variation is making it possible, for the first time, to conduct well-powered searches for the inherited contributors to common diseases and other complex phenotypes. Success will provide insight into the genetic architecture of quantitative characters, the evolutionary history of trait variation, and the etiology of common human diseases. This meeting aims to bring together investigators from population genetics, genomics, quantitative genetics, epidemiology and medical research to examine these problems from a variety of perspectives. Scholarship Deadline: September 13 2005 Discounted Abstract Deadline: October 4 2005 Abstract Deadline: October 4 2005 Discounted Registration Deadline: November 7 2005 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Human Genome Research Institute (NHGRI) Grant No. 1R13 HG003937-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Genome Sequence Variation and the Inherited Basis of Common Disease and Complex Traits

Organizer(s): David M. Altshuler, Peter Donnelly and Trudy F.C. MacKay

Date: January 08 - 13, 2006
Location: Big Sky Resort, Big Sky, MT, USA

Supported by The Director's Fund

For important information on the coronavirus, please click here

Summary of Meeting:

Common human diseases and most other traits vary in a continuous manner, modified by multiple genes and environmental influences. Rapidly expanding information about genome sequence variation is making it possible, for the first time, to conduct well-powered searches for the inherited contributors to common diseases and other complex phenotypes. Success will provide insight into the genetic architecture of quantitative characters, the evolutionary history of trait variation, and the etiology of common human diseases. This meeting aims to bring together investigators from population genetics, genomics, quantitative genetics, epidemiology and medical research to examine these problems from a variety of perspectives.

Scholarship Deadline: September 13 2005

Discounted Abstract Deadline: October 4 2005

Abstract Deadline: October 4 2005

Discounted Registration Deadline: November 7 2005

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Human Genome Research Institute (NHGRI)
Grant No. 1R13 HG003937-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, January 08 \| 3:00PM - 7:30PM Registration Room: Lower Atrium
Sunday, January 08 \| 6:30PM - 7:30PM Refreshments Room: Lower Atrium
Sunday, January 08 \| 7:30PM - 9:30PM Overview Session: Progress and Prospects Room: Gallatin/Madison Speaker 1 of 3 * Peter Donnelly, University of Oxford and Genomics plc, UK
Sunday, January 08 \| 7:30PM - 9:30PM Overview Session: Progress and Prospects Room: Gallatin/Madison Speaker 2 of 3 Trudy F.C. Mackay, North Carolina State University, USA Genetic Analysis of Complex Traits in Drosophila
Sunday, January 08 \| 7:30PM - 9:30PM Overview Session: Progress and Prospects Room: Gallatin/Madison Speaker 3 of 3 David M. Altshuler, Vertex Pharmaceuticals Incorporated, USA Genetic Analysis of Complex Traits in Humans
Monday, January 09 \| 7:00AM - 8:00AM Breakfast Room: Jefferson/Lake/Canyon
Monday, January 09 \| 8:00AM - 11:00AM Genome Sequence Variation Room: Gallatin/Madison Speaker 1 of 5 * Charles H. Langley, University of California, Davis, USA Genomic Patterns of Polymorphism and Divergence: Models and Observations
Monday, January 09 \| 8:00AM - 11:00AM Genome Sequence Variation Room: Gallatin/Madison Speaker 2 of 5 Kelly A. Frazer, University of California San Diego School of Medicine, USA Human DNA Variation and Complex Traits
Monday, January 09 \| 8:00AM - 11:00AM Genome Sequence Variation Room: Gallatin/Madison Speaker 3 of 5 Deborah A. Nickerson, University of Washington, USA SNPs in Candidate Genes
Monday, January 09 \| 8:00AM - 11:00AM Genome Sequence Variation Room: Gallatin/Madison Speaker 4 of 5 Charles Lee, Brigham and Women's Hospital, USA Structural Variations in the Human Genome
Monday, January 09 \| 8:00AM - 11:00AM Genome Sequence Variation Room: Gallatin/Madison Speaker 5 of 5 Penelope E. Bonnen, Rockefeller University, USA Short Talk: Evaluating Potential for Whole Genome Studies in Kosrae - an Isolated Population in Micronesia
Monday, January 09 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Monday, January 09 \| 11:00AM - 1:00PM Poster Setup Room: Jefferson
Monday, January 09 \| 1:00PM - 10:00PM Poster Viewing Room: Jefferson
Monday, January 09 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Monday, January 09 \| 5:00PM - 7:00PM Determinants of Variation: Recombination, Demography, Select ion Room: Gallatin/Madison Speaker 1 of 4 * Peter Donnelly, University of Oxford and Genomics plc, UK Recombination in the Human Genome
Monday, January 09 \| 5:00PM - 7:00PM Determinants of Variation: Recombination, Demography, Select ion Room: Gallatin/Madison Speaker 2 of 4 Molly Przeworski, Columbia University, USA The Signature of Directional Selection on Standing Genetic Variation
Monday, January 09 \| 5:00PM - 7:00PM Determinants of Variation: Recombination, Demography, Select ion Room: Gallatin/Madison Speaker 3 of 4 Jonathan K. Pritchard, Stanford University, USA A High-Resolution Survey of Deletion Polymorphism in the Human Genome.
Monday, January 09 \| 5:00PM - 7:00PM Determinants of Variation: Recombination, Demography, Select ion Room: Gallatin/Madison Speaker 4 of 4 Steven A. McCarroll, Harvard Medical School, USA Short Talk: A Genome-Wide Map of Common Human Deletion Polymorphisms
Monday, January 09 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Jefferson/Lower Atrium
Monday, January 09 \| 7:30PM - 10:00PM Poster Session 1 Room: Jefferson
Tuesday, January 10 \| 7:00AM - 8:00AM Breakfast Room: Jefferson/Lake/Canyon
Tuesday, January 10 \| 8:00AM - 11:00AM Computational Approaches Linking Genotype and Phenotype Room: Gallatin/Madison Speaker 1 of 5 * Heather Cordell, University of Cambridge, UK Multiple Imputation Methods for Genetic Association Analysis of Complex Traits
Tuesday, January 10 \| 8:00AM - 11:00AM Computational Approaches Linking Genotype and Phenotype Room: Gallatin/Madison Speaker 2 of 5 Zhao-Bang Zeng, North Carolina State University, USA QTL Analysis, eQTL Analysis and Genetic Architecture of Complex Traits
Tuesday, January 10 \| 8:00AM - 11:00AM Computational Approaches Linking Genotype and Phenotype Room: Gallatin/Madison Speaker 3 of 5 Andrew G. Clark, Cornell University, USA Population Genetic Methods for Genotype-Phenotype Association
Tuesday, January 10 \| 8:00AM - 11:00AM Computational Approaches Linking Genotype and Phenotype Room: Gallatin/Madison Speaker 4 of 5 Jonathan L. Marchini, University of Oxford, UK Short Talk: A Novel Bayesian Approach to Localising Disease Genes
Tuesday, January 10 \| 8:00AM - 11:00AM Computational Approaches Linking Genotype and Phenotype Room: Gallatin/Madison Speaker 5 of 5 Dan Arking, Johns Hopkins School of Medicine, USA Short Talk
Tuesday, January 10 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Tuesday, January 10 \| 11:00AM - 1:00PM Poster Setup Room: Jefferson
Tuesday, January 10 \| 1:00PM - 10:00PM Poster Viewing Room: Jefferson
Tuesday, January 10 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 1 of 8 * Trudy F.C. Mackay, North Carolina State University, USA
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 2 of 8 Jared Drake, Children's Hospital Boston, USA Conserved Non-Coding Sequences are Selectively Constrained and not Mutation Cold Spots
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 3 of 8 Benjamin F. Voight, University of Chicago, USA A Genome-Wide Scan for Targets of Recent and On-Going Directional Selection in Humans
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 4 of 8 Melanie Bahlo, Walter and Eliza Hall Institute of Medical Research, Australia Linkage Disequilibrium Mapping Malaria Susceptibility Loci in Papua New Guinea
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 5 of 8 Julian T. Forton, University of Oxford, UK Exploiting Allele-Specific Transcript Quantification and the HAPMAP Resource to Localise Long Range Cis-Regulatory Polymorphism
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 6 of 8 Keyan Zhao, Cornell University, USA Genome-Wide Association Mapping in a Structured Population of A. thaliana
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 7 of 8 Minerva M. Carrasquillo, Mayo Clinic, USA A Set of Putative Functional IDE Variants Shows Simple, Replicable Association with Alzheimer’s Disease and has an Estimated Population Attributable Risk of 46%
Tuesday, January 10 \| 5:00PM - 7:00PM Short Talks Room: Gallatin/Madison Speaker 8 of 8 Dana C. Crawford, Case Western Reserve University, USA Genetic Variation is Associated with C-Reactive Protein Levels in a Survey of 7,000 Americans
Tuesday, January 10 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Jefferson/Lower Atrium
Tuesday, January 10 \| 7:30PM - 10:00PM Poster Session 2 Room: Jefferson
Wednesday, January 11 \| 7:00AM - 8:00AM Breakfast Room: Jefferson/Lake/Canyon
Wednesday, January 11 \| 8:00AM - 11:00AM Architecture of Complex Trait Variation Room: Gallatin/Madison Speaker 1 of 6 * Catherine (Katie) L. Peichel, Fred Hutchinson Cancer Research Center, USA Genetic Analysis of Behavioral Differences Between Sympatric Stickleback Species
Wednesday, January 11 \| 8:00AM - 11:00AM Architecture of Complex Trait Variation Room: Gallatin/Madison Speaker 2 of 6 Rachel B. Brem, University of California, Berkeley, USA Transcript Phenotypes and Sequence Variation in Yeast Genomes
Wednesday, January 11 \| 8:00AM - 11:00AM Architecture of Complex Trait Variation Room: Gallatin/Madison Speaker 3 of 6 Wolfgang Stephan, University of Munich, Germany The Role of Selection in Shaping Polymorphism
Wednesday, January 11 \| 8:00AM - 11:00AM Architecture of Complex Trait Variation Room: Gallatin/Madison Speaker 4 of 6 Justin Fay, Washington University, USA Evolution of Transcriptional Regulation
Wednesday, January 11 \| 8:00AM - 11:00AM Architecture of Complex Trait Variation Room: Gallatin/Madison Speaker 5 of 6 Justin P. Gerke, Washington University, USA Short Talk: Analysis of Natural Variation in Yeast Sporulation Efficiency
Wednesday, January 11 \| 8:00AM - 11:00AM Architecture of Complex Trait Variation Room: Gallatin/Madison Speaker 6 of 6 Chao-Qiang Lai, JM-USDA-HNRCA at Tufts University, USA Short Talk: Microarray-based Mapping of QTLs Affecting Lifespan in Drosophila melanogaster
Wednesday, January 11 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Wednesday, January 11 \| 11:00AM - 1:00PM Poster Setup Room: Jefferson
Wednesday, January 11 \| 1:00PM - 10:00PM Poster Viewing Room: Jefferson
Wednesday, January 11 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Wednesday, January 11 \| 5:00PM - 7:00PM Modeling Human Complex Disease Traits in Other Species Room: Gallatin/Madison Speaker 1 of 4 * Gary A. Churchill, The Jackson Laboratory, USA Co-Adaptated Alleles and the Evolution of Complex Traits
Wednesday, January 11 \| 5:00PM - 7:00PM Modeling Human Complex Disease Traits in Other Species Room: Gallatin/Madison Speaker 2 of 4 Joseph H. Nadeau, Maine Medical Center Research Institute, USA
Wednesday, January 11 \| 5:00PM - 7:00PM Modeling Human Complex Disease Traits in Other Species Room: Gallatin/Madison Speaker 3 of 4 J. Lawrence Marsh, University of California, Irvine, USA Identification of Genetic Factors that Affect Huntington’s Disease Pathology in Drosophila
Wednesday, January 11 \| 5:00PM - 7:00PM Modeling Human Complex Disease Traits in Other Species Room: Gallatin/Madison Speaker 4 of 4 Justin O. Borevitz, University of Chicago, USA Short Talk: Genome Wide Association Mapping in Arabidopsis thaliana
Wednesday, January 11 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Jefferson/Lower Atrium
Wednesday, January 11 \| 7:30PM - 10:00PM Poster Session 3 Room: Jefferson
Thursday, January 12 \| 7:00AM - 8:00AM Breakfast Room: Jefferson/Lake/Canyon
Thursday, January 12 \| 8:00AM - 11:00AM Genetic Basis of Human Disease Room: Gallatin/Madison Speaker 1 of 5 Richard P. Lifton, HHMI/Yale University School of Medicine, USA Genetic Basis of Blood Pressure Variation
Thursday, January 12 \| 8:00AM - 11:00AM Genetic Basis of Human Disease Room: Gallatin/Madison Speaker 2 of 5 Jonathan C. Cohen, University of Texas Southwestern Medical Center, USA Genetic Determinants of Plasma Lipoprotein Levels
Thursday, January 12 \| 8:00AM - 11:00AM Genetic Basis of Human Disease Room: Gallatin/Madison Speaker 3 of 5 Leena P. Peltonen, University of Helsinki and National Public Health Inst, Finland From Families to Populations: Example of Finland
Thursday, January 12 \| 8:00AM - 11:00AM Genetic Basis of Human Disease Room: Gallatin/Madison Speaker 4 of 5 Augie Kong, deCODE genetics, Iceland Complex Diseases and Association Studies
Thursday, January 12 \| 8:00AM - 11:00AM Genetic Basis of Human Disease Room: Gallatin/Madison Speaker 5 of 5 Jenny C. Lee, University of California, Los Angeles, USA Short Talk: Human Sequence Variation Data Facilitates the Fine Mapping of a Low High-Density Lipoprotein Cholesterol Region on Chromosome 16q23-24
Thursday, January 12 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Thursday, January 12 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Thursday, January 12 \| 5:00PM - 7:00PM Genetics, Medicine and Society Room: Gallatin/Madison Speaker 1 of 4 * David M. Altshuler, Vertex Pharmaceuticals Incorporated, USA
Thursday, January 12 \| 5:00PM - 7:00PM Genetics, Medicine and Society Room: Gallatin/Madison Speaker 2 of 4 Joel N. Hirschhorn, Children's Hospital, Boston, USA New Insights into the Genetics of Obesity and Cardiovascular Traits
Thursday, January 12 \| 5:00PM - 7:00PM Genetics, Medicine and Society Room: Gallatin/Madison Speaker 3 of 4 Kang Zhang, University of Utah, USA Short Talk: Genetic Study of Diabetic Complications, Age-Related Macular Degeneration, and Glaucoma Using the Utah Population Database
Thursday, January 12 \| 5:00PM - 7:00PM Genetics, Medicine and Society Room: Gallatin/Madison Speaker 4 of 4 Nicole M. Walley, Duke University, USA Short Talk
Thursday, January 12 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Jefferson/Lower Atrium
Thursday, January 12 \| 8:00PM - 11:00PM Entertainment Room: Jefferson
Thursday, January 12 \| 8:00PM - 11:00PM Cash Bar Room: Jefferson
Friday, January 13 \| 10:21AM - 10:21AM Departure *Session Chair †Invited, not yet responded.