Web Desc
Chemokines and Chemokine Receptors
Organizer(s): Andrew Luster and Philip Murphy
Date: January 15 - 20, 2006
Location: Snowbird Resort, Snowbird, UT, USA
Supported by The Director's Fund
Summary of Meeting:
Chemokines are chemotactic cytokines that induce the directed migration of cells by activating specific G protein-coupled receptors. This system of ~50 cytokines and ~20 receptors plays a particularly prominent role in development, homeostasis and activation of leukocytes in the mammalian immune system. Chemokines determine the nature of the tissue inflammatory response in a wide range of human diseases and represent attractive new therapeutic targets. Chemokines may also attract and stimulate non-immune cells, such as tumor cells, neurons and blood vessels. This meeting will address major unanswered questions in the chemokine field including how chemokines regulate lymphoid development, how cells sense chemokine gradients, the nature of the chemokine signaling pathway, how chemokines amplify immunologically-mediated disease, and whether disrupting chemokine signaling can treat or prevent disease. A systems biology approach to chemokine function in vivo will be highlighted and will extend to the regulation and interrelationship of the chemokine system with other regulatory systems in vivo.
Scholarship Deadline: September 15 2005
Discounted Abstract Deadline: September 15 2005
Abstract Deadline: October 6 2005
Discounted Registration Deadline: November 15 2005
We gratefully acknowledge additional support for this conference from:
Educational donation provided by AmgenNovartis Institutes for BioMedical Research
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

EMD Serono, Inc.

Merck Research Laboratories
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI066862-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 15 | 3:00PM - 7:30PM
Registration
Room: Ballroom Lobby


Sunday, January 15 | 6:30PM - 7:30PM
Refreshments
Room: Ballroom Mezzanine & Lobby


Sunday, January 15 | 7:30PM - 8:30PM
Keynote Address
Room: Ballroom 2-3

Speaker 1 of 1
Eugene C. Butcher, Stanford University, USA
Leukocyte-Endothelial Cell Recognition: Toward a General Model of Leukocyte Trafficking

Monday, January 16 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff, Wasatch, Superior Lobby


Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 1 of 8
* Martin Lipp, Max-Delbrueck-Center, MDC, Germany

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 2 of 8
Ulrich H. Von Andrian, Harvard Medical School, USA
T Cell and DC Trafficking in the Lymph Node

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 3 of 8
Reinhold Förster, Hannover Medical School, Germany
DC Migraton in Tolerance and Immunity

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 4 of 8
Hans-Christian Reinecker, Massachusetts General Hospital, USA
Short Talk: Chemokine Receptors Regulate Intestinal DC Subsets in Mucosal Defense

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 5 of 8
Federica Sallusto, Università della Svizzera Italiana & ETH Zurich, Switzerland
Leukocyte Trafficking to the Inflamed Lymph Node

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 6 of 8
Joshua M. Farber, NIAID, National Institutes of Health, USA
Chemokines in CD4+ T Cell Memory

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 7 of 8
Thomas B. Issekutz, Dalhousie University, Canada
Short Talk: Migration of CCR4+ Memory CD4 T Cells to Dermal Inflammation is Mediated by CXCR3

Monday, January 16 | 8:00AM - 11:30AM
Chemokine Control of Leukocyte Trafficking in the Adaptive I
mmune Response

Room: Ballroom 2-3

Speaker 8 of 8
Hanna Stenstad, Sahlgrenska Academy, Sweden
Short Talk: Gut Associated Lymphoid Tissue Primed CD4+ T Cells Display CCR9 Dependent and Independent Homing to the Murine Small Intestine

Monday, January 16 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Mezzanine & Lobby


Monday, January 16 | 11:30AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby/Maybird


Monday, January 16 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby/Maybird


Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 1 of 10
* Osamu Yoshie, Kinki University, Japan

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 2 of 10
* Joost J. Oppenheim, National Institutes of Health, USA
Alarmins are Non-Cognate Chemokine Receptor Ligands and Activators of Dendritic Cells

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 3 of 10
Brigitte Gomperts, University of California, Los Angeles, USA
Circulating Progenitor Epithelial Cells Traffic via CXCR4/CXCL12 in Response to Airway Injury

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 4 of 10
Yang Hu, Weill Graduate School of Medical Sciences of Cornell University, USA
Costimulation of Chemokine Receptor Signaling by MMP-9 Mediates Enhanced Migration of IFNá-DCs

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 5 of 10
George Ed Rainger, University of Birmingham, UK
A Multi-Cellular in Vitro Model of Chronic Inflammatory Joint Disease Identifies Novel Routes of Chemokine Expression Presentation and Function

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 6 of 10
Ewan A. Ross, University of Glasgow, UK
Platelet Endothelial Cell Adhesion Molecule (Pecam)-1 Modulates
Sdf-1alpha/Cxcr4 Responses of Hematopoietic Stem Cells


Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 7 of 10
Marcus Svensson, Lund University, Sweden
Role of CCR9 in Thymic T Cell Development

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 8 of 10
Raffaella Bonecchi, Istituto Clinico Humanitas, Italy
The Chemokine Decoy Receptor D6 Protects the Fetus from Inflammation Acting as an Inflammatory CC Chemokine Scavenger at the Fetal-Maternal Interface

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 9 of 10
Gabriele S.V. Campanella, Massachusetts General Hospital, USA
IP-10 (CXCL10) Oligomerization is Important for its in Vivo Activity

Monday, January 16 | 2:00PM - 4:30PM
Workshop 1: Novel Chemokine Biology
Room: Ballroom 2-3

Speaker 10 of 10
Jana Barlic, National Institutes of Health, USA
Oxidized LDL Metabolites Upregulate Expression and Function of Monocyte CX3CR1 through a PPARgamma-dependent Pathway

Monday, January 16 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Mezzanine & Lobby


Monday, January 16 | 5:00PM - 7:15PM
Chemokines in Immune System Homeostasis
Room: Ballroom 2-3

Speaker 1 of 6
* Bernhard Moser, Cardiff University School of Medicine, UK
Steady-State T Cell Traffick in Human Skin

Monday, January 16 | 5:00PM - 7:15PM
Chemokines in Immune System Homeostasis
Room: Ballroom 2-3

Speaker 2 of 6
Mehrdad Matloubian, University of California, San Francisco, USA
Regulation of Lymphocyte Exit from Lymphoid Organs

Monday, January 16 | 5:00PM - 7:15PM
Chemokines in Immune System Homeostasis
Room: Ballroom 2-3

Speaker 3 of 6
Hugh Rosen, ActivX Biosciences, USA
S1P1 Control of Lymphocyte Trafficking

Monday, January 16 | 5:00PM - 7:15PM
Chemokines in Immune System Homeostasis
Room: Ballroom 2-3

Speaker 4 of 6
Shannon Bromley, Massachusetts General Hospital, USA
Short Talk: CCR7 Guides T Cell Exit from Peripheral Tissues and Entry into Afferent Lymphatic

Monday, January 16 | 5:00PM - 7:15PM
Chemokines in Immune System Homeostasis
Room: Ballroom 2-3

Speaker 5 of 6
Ariel Achtman, Max-Delbrück-Centrum für Molekulare Medizin, Germany
Short Talk: CCR7 Deficiency Leads to Disturbed Lymphocyte Recirculation through Non-Lymphoid Tissues and Causes Hypertrophic Gastropathy

Monday, January 16 | 5:00PM - 7:15PM
Chemokines in Immune System Homeostasis
Room: Ballroom 2-3

Speaker 6 of 6
Shahin Rafii, Weill Cornell Medical College, USA
Chemokine-Mediated Interaction of Hematopoietic Progenitors with the Bone Marrow Vascular Niche

Monday, January 16 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby/Maybird


Monday, January 16 | 7:30PM - 10:00PM
Poster Session 1
Room: Superior/Superior Lobby/Maybird


Tuesday, January 17 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff, Wasatch, Superior Lobby


Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 1 of 7
* Ann Richmond, Vanderbilt University School of Medicine, USA
Localiztion of Signaling Events in Chemotaxing

Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 2 of 7
Ronen Alon, Weizmann Institute of Science, Israel
Chemokine Regulation of Lymphocyte Adhesion and Migration

Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 3 of 7
Tatsuo Kinashi, Kansai Medical School, Japan
Roles of Rap1-RAPL in Chemokine-Mediated Immune Cell Migration

Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 4 of 7
Dianqing Dan Wu, Yale University School of Medicine, USA
Genetic Study of Chemoattractant Signaling

Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 5 of 7
Antonella Viola, University of Milan, Italy
Orchestration of Leukocyte Chemotaxis by Mitochondrial Dynamics

Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 6 of 7
Jens V. Stein, University of Bern, Switzerland
Short Talk: A Central Role for DOCK2 During Interstitial T and B Lymphocyte Migration and Lymph Node Egress

Tuesday, January 17 | 8:00AM - 11:15AM
Chemoattractant Signal Transduction
Room: Ballroom 2-3

Speaker 7 of 7
Barbara Walzog, Ludwig-Maximilians-Universität, Germany
Short Talk: The Vav Binding Site of the Non-Receptor Tyrosine Kinase Syk at Tyr 348 Is Critical for Beta2 Integrin (CD11/CD18)-Mediated Leukocyte Polarization and Migration

Tuesday, January 17 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Mezzanine & Lobby


Tuesday, January 17 | 11:30AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby/Maybird


Tuesday, January 17 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby/Maybird


Tuesday, January 17 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Mezzanine & Lobby


Tuesday, January 17 | 5:00PM - 7:15PM
Regulation of Chemokine Action
Room: Ballroom 2-3

Speaker 1 of 5
* Gerry J. Graham, University of Glasgow, UK
The Chemokine Decoy Receptor, D6, Regulates the Inflammatory Response in vivo

Tuesday, January 17 | 5:00PM - 7:15PM
Regulation of Chemokine Action
Room: Ballroom 2-3

Speaker 2 of 5
Frances E. Lund, University of Alabama at Birmingham, USA
Regulation of Cell Trafficking under Homeostatic and Inflammatory Conditions: Roles for CD38, cADPR and Galphaq

Tuesday, January 17 | 5:00PM - 7:15PM
Regulation of Chemokine Action
Room: Ballroom 2-3

Speaker 3 of 5
Christopher M. Overall, University of British Columbia, Canada
Dynamic Regulation of the Chemokine Web by Matrix Metalloproteinases

Tuesday, January 17 | 5:00PM - 7:15PM
Regulation of Chemokine Action
Room: Ballroom 2-3

Speaker 4 of 5
Ifor Williams, Science Immunology, USA
Short Talk: Developmental Regulation of Sulfation of N-Terminal Tyrosine of Mouse CCR9 by Tyrsoylprotein Sulfotransferase-2

Tuesday, January 17 | 5:00PM - 7:15PM
Regulation of Chemokine Action
Room: Ballroom 2-3

Speaker 5 of 5
Andrea Meiser, Imperial College, Faculty of Medicine, UK
Short Talk: The Chemokine Receptor CXCR3 is Replenished at the Cell Surface by de novo Synthesis of Receptor and not by Receptor Recycling

Tuesday, January 17 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby/Maybird


Tuesday, January 17 | 7:30PM - 10:00PM
Poster Session 2
Room: Superior/Superior Lobby/Maybird


Wednesday, January 18 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff, Wasatch, Superior Lobby


Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 1 of 9
* Richard M. Ransohoff, Third Rock Ventures, USA
EAE in D6-/- Mice

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 2 of 9
Klaus Ley, La Jolla Institute for Allergy and Immunology, USA
Arrest Chemokines in Atherosclerosis: Specialized Receptors and Signaling Pathways

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 3 of 9
Seema S. Ahuja, University of Texas Health Science Center, USA
Chemokines and Chemokine Receptors in Rheumatoid Arthritis

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 4 of 9
Thomas J. Schall, ChemoCentryx, Inc., USA
Novel Chemokines and Chemokine Receptors in Development and Disease

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 5 of 9
Israel F. Charo, ChemoCentryx, Inc., USA
Chemokines and the Metabolic Syndrome

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 6 of 9
Robert E. Gerszten, Beth Israel Deaconess Medical Center, USA
Short Talk: The T Cell Chemokine CXCL10 (IP-10) Modulates Atherogenesis via the Local Balance of the Effector and Regulatory Arms of the Immune System

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 7 of 9
Nikolaos G. Frangogiannis, Baylor College of Medicine, USA
Short Talk: Role of the C-C Chemokines in Myocardial Infarction

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 8 of 9
Amnon Peled, Hebrew University, Israel
Role of Chemokine Receptors in NK Cell Mobilization and Trafficking

Wednesday, January 18 | 8:00AM - 11:30AM
Chemokines in Immunologically-Mediated Disease I
Room: Ballroom 2-3

Speaker 9 of 9
Toshihiro Nanki, Teikyo University, Japan
Short Talk: Pathogenic Role of CXCL16-CXCR6 Pathway in Rheumatoid Arthritis

Wednesday, January 18 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Mezzanine & Lobby


Wednesday, January 18 | 11:00AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby/Maybird


Wednesday, January 18 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby/Maybird


Wednesday, January 18 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Mezzanine & Lobby


Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 1 of 7
* Craig Gerard, Children's Hospital Harvard University, USA

Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 2 of 7
Nicholas W. Lukacs, University of Michigan, USA
Chemokine Receptors and Chronic Airway Disease

Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 3 of 7
Dan R. Littman, HHMI/New York University School of Medicine, USA
Chemokines in Myeloid and T Cell Function

Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 4 of 7
Richard M. Ransohoff, Third Rock Ventures, USA

Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 5 of 7
Joseph El Khoury, Massachusetts General Hospital, USA
Short Talk: Chemokine Regulation of Microglial Recruitment in Alzheimer's Disease

Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 6 of 7
Jesús Rivera-Nieves, Inflammatory Bowel Disease Center, USA
Short Talk: Role of CCR9/CCL25 in Chronic Murine Ileitis

Wednesday, January 18 | 5:00PM - 7:30PM
Chemokines in Immunologically-Mediated Disease II
Room: Ballroom 2-3

Speaker 7 of 7
Julie A. DeMartino, EMD Serono Research & Development Institute, Inc., USA
Updates and Future Directions of Anti-Chemokine Therapeutics

Wednesday, January 18 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby/Maybird


Wednesday, January 18 | 7:30PM - 10:00PM
Poster Session 3
Room: Superior/Superior Lobby/Maybird


Thursday, January 19 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff, Wasatch, Superior Lobby


Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 1 of 8
* Steven L. Kunkel, University of Michigan Medical School, USA

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 2 of 8
Antonio Alcami, Centro de Biologia Molecular Severo Ochoa, Spain
Viral Chemokine Binding Proteins

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 3 of 8
Eric G. Pamer, University of Chicago, USA
Regulation of Leukocyte Trafficking during Infection

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 4 of 8
Kouji Matsushima, University of Tokyo School of Medicine, Japan
Chemokine-Regulated Subsets of DCs in Anti-Viral Immunity

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 5 of 8
Michael J. Holtzman, Washington University in St. Louis, USA
Chemokine Protection from Virus-Induced Cell Death

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 6 of 8
Jean K. Lim, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Chemokine Receptor CCR5 Mediates Resistance to West Nile Virus Infection in Mouse and Man

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 7 of 8
Fang Liao, Academia Sinica, Taiwan
Short Talk: Both CXCR3 and CXCL10/IP-10 are Required for Resistance to Primary Infection by Dengue Virus

Thursday, January 19 | 8:00AM - 11:30AM
Chemokines and Infectious Disease
Room: Ballroom 2-3

Speaker 8 of 8
Kathleen Kelly, University of California Los Angeles, USA
Short Talk: CXCL13 is Induced within Human Fallopian Tubes Following Infection with Chlamydia and Alters Oviduct Pathology

Thursday, January 19 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Mezzanine & Lobby


Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 1 of 10
* Amanda E.I. Proudfoot Fichard, Merck Serono Geneva Research Centre, Switzerland

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 2 of 10
* Albert Zlotnik, University of California Irvine, USA
Diagnostic and Therapeutic Uses of Chemokines

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 3 of 10
Andreas J. Kungl, ProtAffin Biotechnologie AG, Austria
Developing Receptor-Deficient Chemokine Mutants Towards Glycosaminoglycan Antagonists: The CellJammer Anti-Inflammatory Approach

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 4 of 10
Andrea Martin, Eli Lilly and Company, USA
The Chemokine Binding Protein M3 Prevents Inflammatory and Autoimmune Diabetes

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 5 of 10
Christina Anne Bursill, Heart Reserach Institute, Australia
Membrane-Bound CC-Chemokine Inhibitor ‘M35K’ Provides Localised Inhibition of CC-Chemokine Activity in Vitro and in Vivo


Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 6 of 10
Jen Alexander-Brett, Washington University, USA
Promiscuous Chemokine Sequestration By a Herpesvirus Decoy Receptor

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 7 of 10
R. William Hipkin, Schering-Plough Research Institute, USA
The Affinity and Intrinsic Activity of Chemokines at hCXCR1 and hCSCR2: CXCL8 is Functionally CXCR1-Selective

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 8 of 10
Kathleen A. Sullivan, Merck & Co., Inc., USA
In Vivo Consequences of CXCR3 Blockade with Small Molecule Antagonists

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 9 of 10
Kenneth R. Cooke, Johns Hopkins, USA
CCR1:CCL5 (RANTES) Receptor:Ligand Interactions Modulate Allogeneic T Cell Responses Following Allogeneic Bone Marrow Transplantation

Thursday, January 19 | 2:00PM - 4:30PM
Workshop 2: Preclinical and Clinical Development of Anti-Che
mokine Therapy for Disease
Room: Ballroom 2-3

Speaker 10 of 10
Oliver Dewald, Klinikum Oldenburg, Germany
CCL2/MCP-1 Deficiency Prevents Development of Ischemic Cardiomyopathy Decreasing Interstitial Fibrosis

Thursday, January 19 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Mezzanine & Lobby


Thursday, January 19 | 5:00PM - 7:15PM
Chemokines in Cancer and Development
Room: Ballroom 2-3

Speaker 1 of 6
* Robert M. Strieter, University of Virginia School of Medicine, USA
Chemokines and Cancer

Thursday, January 19 | 5:00PM - 7:15PM
Chemokines in Cancer and Development
Room: Ballroom 2-3

Speaker 2 of 6
Fabienne Mackay, Monash University, Australia
CXCR7 Deficient Mice Reveal a Key Role for this Receptor in Cardiac Development and Splenic Marginal Zone B Cell Formation

Thursday, January 19 | 5:00PM - 7:15PM
Chemokines in Cancer and Development
Room: Ballroom 2-3

Speaker 3 of 6
Tyler J. Curiel, University of Texas Health, USA
Chemokines in Cancer Pathogenesis

Thursday, January 19 | 5:00PM - 7:15PM
Chemokines in Cancer and Development
Room: Ballroom 2-3

Speaker 4 of 6
Sergio A. Lira, Mount Sinai School of Medicine, USA
Tumorigenesis Induced by the HHV8-Encoded Chemokine Receptor

Thursday, January 19 | 5:00PM - 7:15PM
Chemokines in Cancer and Development
Room: Ballroom 2-3

Speaker 5 of 6
Gwendal Lazennec, INSERM, France
Short Talk: IL-8 is a Novel Marker for Breast Cancer

Thursday, January 19 | 5:00PM - 7:15PM
Chemokines in Cancer and Development
Room: Ballroom 2-3

Speaker 6 of 6
Hiroshi Miyazaki, Philips Institute-Virginia Commonwealth University, USA
Short Talk: Regulation of Squamous Cell Carcinoma Proliferation and Invasion by CXCL5

Thursday, January 19 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Golden Cliff, Eagles Nest, Superior Lobby


Thursday, January 19 | 8:00PM - 11:00PM
Entertainment
Room: Golden Cliff, Eagles Nest, Superior Lobby


Thursday, January 19 | 8:15PM - 11:00PM
Cash Bar
Room: Golden Cliff, Eagles Nest, Superior Lobby


Friday, January 20 | 10:26AM - 10:26AM
Departure


*Session Chair.