Web Desc
Signaling Networks
Organizer(s): René Bernards and Marc Vidal
Date: January 30 - February 04, 2006
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada
Supported by The Director's Fund
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Summary of Meeting:
Communication through networks of interacting proteins is a central feature of all living organisms. Dissecting the components of these signaling pathways and the functional relationships between them is crucial to our understanding of biological processes. Recent technological developments, especially RNA interference, have provided powerful new tools for functional identification of components of signaling networks. The goal of this meeting is to show how functional genetic approaches can be used to study signaling networks.
Scholarship Deadline: September 29 2005
Discounted Abstract Deadline: September 29 2005
Abstract Deadline: October 24 2005
Discounted Registration Deadline: November 30 2005
We gratefully acknowledge additional support for this conference from:
Cell Signaling Technology, Inc.Educational donation provided by AmgenNovartis Institutes for BioMedical Research
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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Program

Monday, January 30 | 3:00PM - 7:00PM
Registration
Room: BC Foyer


Monday, January 30 | 7:00PM - 8:00PM
Refreshments
Room: BC Foyer


Monday, January 30 | 8:00PM - 9:00PM
Keynote Address
Room: British Ballroom

Speaker 1 of 1
Norbert Perrimon, Harvard Medical School, USA
Getting Closer to Biology in RNAi Highthroughput Screens: The Use of Primary Cells

Tuesday, January 31 | 7:00AM - 8:00AM
Breakfast
Room: Columbia Ballroom


Tuesday, January 31 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks I
Room: British Ballroom

Speaker 1 of 5
Ronald H. Plasterk, Ministry of Education, Culture and Science, Netherlands
MicroRNAs in Animal Development

Tuesday, January 31 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks I
Room: British Ballroom

Speaker 2 of 5
Philip A. Beachy, HHMI/Stanford University, USA
Drosophila Signaling Networks

Tuesday, January 31 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks I
Room: British Ballroom

Speaker 3 of 5
† Michael Hannus, Cenix BioScience GmbH, Germany
Genome-Scale RNAi Screening in Human Cells

Tuesday, January 31 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks I
Room: British Ballroom

Speaker 4 of 5
David A. Guertin, University of Massachusetts Medical School, USA
Short Talk: A Combinatorial Functional Genomics Approach Identifies TOR-Regulated Genes that Control Growth

Tuesday, January 31 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks I
Room: British Ballroom

Speaker 5 of 5
Jose M. Silva, Cold Spring Harbor Laboratory, USA
RNAi as a Tool to Unravel Mammalian Signaling Networks

Tuesday, January 31 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Tuesday, January 31 | 11:00AM - 1:00PM
Poster Setup
Room: Columbia Ballroom


Tuesday, January 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Columbia Ballroom


Tuesday, January 31 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Tuesday, January 31 | 5:00PM - 7:00PM
RNAi as a Tool to Study Signaling Networks II
Room: British Ballroom

Speaker 1 of 4
Julian H. Downward, Cancer Research UK, UK
Using Genome-Scale RNAi to Investigate Ras Oncogenic Signaling Networks

Tuesday, January 31 | 5:00PM - 7:00PM
RNAi as a Tool to Study Signaling Networks II
Room: British Ballroom

Speaker 2 of 4
René Bernards, Netherlands Cancer Institute, Netherlands
Deciphering Cancer-Relevant Signaling Networks through RNA Interference-Based Genetic Screens.

Tuesday, January 31 | 5:00PM - 7:00PM
RNAi as a Tool to Study Signaling Networks II
Room: British Ballroom

Speaker 3 of 4
Michael Ollmann, Amgen Inc, USA
Short Talk: Synthetic Interaction Screens by RNAi in Drosophila Cells Identify PTEN-Dependent Survival Genes

Tuesday, January 31 | 5:00PM - 7:00PM
RNAi as a Tool to Study Signaling Networks II
Room: British Ballroom

Speaker 4 of 4
A.J. Marian Walhout, University of Massachusetts Medical School, USA
C. elegans Transcription Regulatory Networks

Tuesday, January 31 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Columbia Ballroom


Tuesday, January 31 | 7:30PM - 10:00PM
Poster Session 1
Room: Columbia Ballroom


Wednesday, February 01 | 7:00AM - 8:00AM
Breakfast
Room: Columbia Ballroom


Wednesday, February 01 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks III
Room: British Ballroom

Speaker 1 of 5
Gary B. Ruvkun, Massachusetts General Hospital, Harvard Medical School, USA
C. elegans RNAi Screens

Wednesday, February 01 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks III
Room: British Ballroom

Speaker 2 of 5
Sumit Chanda, Sanford Burnham Prebys Medical Discovery Institute, USA
Elucidation of Novel Gene Function through Genome-scale Functional Profiling in Mammalian Cells

Wednesday, February 01 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks III
Room: British Ballroom

Speaker 3 of 5
David M. Sabatini, Whitehead Institute for Biomedical Research, USA
Cell-Based RNAi Screening

Wednesday, February 01 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks III
Room: British Ballroom

Speaker 4 of 5
Andrew Fraser, Wellcome Trust Sanger Institute, UK
RNAi Screens to Map Genetic Interactions in C. elegans Development

Wednesday, February 01 | 8:00AM - 11:00AM
RNAi as a Tool to Study Signaling Networks III
Room: British Ballroom

Speaker 5 of 5
Alon Kaufman, Hebrew University of Jerusalem, Israel
Short Talk: Novel Methods for Functional Pathway Identification via Genetic Perturbations

Wednesday, February 01 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Wednesday, February 01 | 11:00AM - 1:00PM
Poster Setup
Room: Columbia Ballroom


Wednesday, February 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Columbia Ballroom


Wednesday, February 01 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Wednesday, February 01 | 5:00PM - 7:00PM
Interactome Networks
Room: British Ballroom

Speaker 1 of 4
Marc Vidal, Dana-Farber Cancer Institute, USA
Interactome Networks

Wednesday, February 01 | 5:00PM - 7:00PM
Interactome Networks
Room: British Ballroom

Speaker 2 of 4
Giulio Superti-Furga, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria
Molecular Networks and Drug Action

Wednesday, February 01 | 5:00PM - 7:00PM
Interactome Networks
Room: British Ballroom

Speaker 3 of 4
Myrto Raftopoulou, Nature Cell Biology, UK
Short Talk: Signaling Gateway: The Molecule Pages Database

Wednesday, February 01 | 5:00PM - 7:00PM
Interactome Networks
Room: British Ballroom

Speaker 4 of 4
Nevan J. Krogan, University of California, San Francisco, USA
Short Talk: Protein Complexes and Pathways Involved in Chromosome Function


Wednesday, February 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Columbia Ballroom


Wednesday, February 01 | 7:30PM - 10:00PM
Poster Session 2
Room: Columbia Ballroom


Thursday, February 02 | 7:00AM - 8:00AM
Breakfast
Room: Columbia Ballroom


Thursday, February 02 | 8:00AM - 11:00AM
Functional Logics of Networks
Room: British Ballroom

Speaker 1 of 5
Timothy R. Hughes, University of Toronto, Canada
The Functional Landscape of Vertebrate Gene Expression

Thursday, February 02 | 8:00AM - 11:00AM
Functional Logics of Networks
Room: British Ballroom

Speaker 2 of 5
Ravi Iyengar, Mount Sinai Medical Center, USA
Cell Signaling Networks

Thursday, February 02 | 8:00AM - 11:00AM
Functional Logics of Networks
Room: British Ballroom

Speaker 3 of 5
Elizabeth A. Winzeler, University of California, San Diego, USA
Functional Genomics of the Malaria Parasite

Thursday, February 02 | 8:00AM - 11:00AM
Functional Logics of Networks
Room: British Ballroom

Speaker 4 of 5
Jef D. Boeke, New York University Langone Medical Center, USA
Analyzing the DNA Integrity Network in Saccharomyces cerevisiae

Thursday, February 02 | 8:00AM - 11:00AM
Functional Logics of Networks
Room: British Ballroom

Speaker 5 of 5
Valentina Perissi, Boston University School of Medicine, USA
Short Talk: The TBL1/TBLR1-Containing NCo-Ex Complex is Modulated by a Network of Signaling Pathways.

Thursday, February 02 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Thursday, February 02 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Thursday, February 02 | 5:00PM - 7:00PM
From Datasets to Network Models
Room: British Ballroom

Speaker 1 of 4
Cornelia Bargmann, Rockefeller University and Chan Zuckerberg Initiative, USA
Neuronal Networks

Thursday, February 02 | 5:00PM - 7:00PM
From Datasets to Network Models
Room: British Ballroom

Speaker 2 of 4
Galit Lahav, Harvard Medical School, USA
Integrating Models and Experiments to Understand p53’s Ups and Downs

Thursday, February 02 | 5:00PM - 7:00PM
From Datasets to Network Models
Room: British Ballroom

Speaker 3 of 4
Albert-László Barabási, Northeastern University, USA
Protein Interaction Networks

Thursday, February 02 | 5:00PM - 7:00PM
From Datasets to Network Models
Room: British Ballroom

Speaker 4 of 4
Einat Sprinzak, University of California, Los Angeles, USA
Short Talk: Applying Logic Relations to Derive Pathways from Genome-Wide Data

Thursday, February 02 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Columbia Ballroom


Friday, February 03 | 7:00AM - 8:00AM
Breakfast
Room: Columbia Ballroom


Friday, February 03 | 8:00AM - 11:00AM
Networks and Biology
Room: British Ballroom

Speaker 1 of 5
Justin Lamb, Broad Institute of MIT and Harvard, USA
A Transcriptional Connectivity Map for Biomedical Discovery

Friday, February 03 | 8:00AM - 11:00AM
Networks and Biology
Room: British Ballroom

Speaker 2 of 5
Smadar Ben-Tabou DeLeon, California Institute of Technology, USA
Gene Regulatory Network Controlling Endomesoderm Specification in the Sea Urchin Embryo

Friday, February 03 | 8:00AM - 11:00AM
Networks and Biology
Room: British Ballroom

Speaker 3 of 5
Inmaculada Segura, VIB-K.U.Leuven, Belgium
Short Talk: Transgenic Mouse Proteomics Identifies New 14-3-3 Associated Proteins Involved in Cytoskeletal Rearrangements and Cell Signaling

Friday, February 03 | 8:00AM - 11:00AM
Networks and Biology
Room: British Ballroom

Speaker 4 of 5
Alexander Tarakhovsky, Rockefeller University, USA
Short Talk: Dual Function of the Polycomb Group Protein Ezh2 in Nuclear and Cytosolic Signaling


Friday, February 03 | 8:00AM - 11:00AM
Networks and Biology
Room: British Ballroom

Speaker 5 of 5
Søren J. Nielsen, Nuevolution, Denmark
Short Talk: Pathway Profiling of Compounds with Defined Mode-of-Action Using Redistribution® Technology to Identify Novel Pathway Connections

Friday, February 03 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Friday, February 03 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Friday, February 03 | 5:00PM - 7:00PM
Transcriptional Networks
Room: British Ballroom

Speaker 1 of 3
Richard A. Young, Whitehead Institute for Biomedical Research, USA
Transcriptional Networks

Friday, February 03 | 5:00PM - 7:00PM
Transcriptional Networks
Room: British Ballroom

Speaker 2 of 3
Eric Schadt, Mount Sinai School of Medicine, USA
Interactions Among Gene Networks Reconstructed from Multiple Tissues in Segregating Mouse Populations and Underlying Complex Disease Traits

Friday, February 03 | 5:00PM - 7:00PM
Transcriptional Networks
Room: British Ballroom

Speaker 3 of 3
Isidore Rigoutsos, International Business Machines Corporation, USA
Short Talk: Extremely-Well-Conserved Blocks Link the Non-Coding and Gene-Coding Regions of the Human Genome and Suggest the Existence of an Endogenous, Previously-Unseen Layer of Cell Process Regulation

Friday, February 03 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Columbia Ballroom


Friday, February 03 | 8:00PM - 11:00PM
Entertainment
Room: Columbia Ballroom


Friday, February 03 | 8:00PM - 11:00PM
Cash Bar
Room: Columbia Ballroom


Saturday, February 04 | 10:21AM - 10:21AM
Departure


*Session Chair
†Invited, not yet responded.