G Protein-Coupled Receptors: Evolving Concepts and New Techniques

Organizer(s): Paul A. Insel, Graeme Milligan and Dianne M. Perez

Supported by The Director's Fund

Summary of Meeting:

G-protein-coupled receptors (GPCRs), which comprise one of the largest gene families identified in the human genome, also represent the largest number of currently used targets of therapeutic drugs. Recent work has indicated a number of intriguing observations in terms of GPCR structure, function and regulation, including existence of receptor homodimers and heterodimers, genetic identification of orphan GPCRs, novel receptor interacting proteins, mechanisms involved in receptor deactivation/desensitization, and receptor targeting/action in signalling microdomains. Definitive information about each of these topics is still being developed. This symposium will focus on these and related topics with an emphasis on use of new tools, e.g., bioinformatic approaches to evaluate GPCR family members, novel strategies to identify ligands active at GPCRs, and insights from non-mammalian/lower eukaryotic systems.

Scholarship Deadline: October 12 2005

Discounted Abstract Deadline: October 12 2005

Abstract Deadline: November 3 2005

Discounted Registration Deadline: December 12 2005

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