Multi-Protein Complexes Involved in Cell Regulation

Organizer(s): Tom L. Blundell, Carol V. Robinson and Ralph A. Bradshaw

Supported by The Director's Fund

Summary of Meeting:

As knowledge of protein structure advances it has become increasingly clear that protein interactions, both transient and stable, are far more extensive than originally appreciated and that the resulting complexes, with a very wide range of stabilities, form highly coordinated networks that govern biological processes. Understanding the fluxes of information that are transmitted by these protein-protein contacts is the essence of systems biology and is dependent, at least to a first approximation, on determining the structures of the proteins involved. There have been multiple approaches to this challenging problem ranging from crystallography and 2D NMR to hybridization and mass spectrometry. This meeting will assess the state of determining the structural and functional bases for protein-protein interactions with the view of exploring how these approaches augment and extend each other.

Scholarship Deadline: April 18 2006

Discounted Abstract Deadline: May 9 2006

Abstract Deadline: May 26 2006

Discounted Registration Deadline: June 19 2006

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