Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Immunological Intervention in Human Disease (2007A2)

Web Desc
Pathogen-Host Standoff: Persistent and Latent Infection joint with Determinants of Host Resistance, Susceptibility or Immunopathology to Pathogens: Integrating Knowledge from Experimental Models to Human Disease Organizer(s): Edward S. Mocarski Jr. and JoAnne L. Flynn Date: January 05 - 10, 2006 Location: Keystone Resort, Keystone, CO, USA Supported by the Burroughs Wellcome Fund Summary of Meeting: Exciting current research: - Common host immune mechanisms interface with a variety of microbes. - Immune modulation and evasion strategies still expanding in scope. - Immune response does not equal clearance; protective immunity still being defined. Problems in the field: - How to effectively enhance an immune response to eliminate an organism that has evolved to be persistent in the host. - How to integrate information about the immune response to acute disease in the context of chronic and latent infections. - How to categorize the persistent or latent state of a pathogen, and determine the genetic components that contribute to latency. - Bring together scientists from different fields to think about the concepts of latency and persistence, and share ideas from different fields. Goals: - Understand common themes in latent microbial infections, regardless of whether a virus, bacterium, parasite, worm, or fungus. - Contrast differences in immunologic memory during acute, chronic and latent infection (important in design of vaccine or treatment strategies). - Understand common immune mechanisms controlling latent or persistent microbes. - Identify strategies by which pathogens escape detection or elimination by the immune system, and design strategies to circumvent these pathogens (vaccine or drug development). Scholarship Deadline: September 13 2005 Discounted Abstract Deadline: September 13 2005 Abstract Deadline: October 3 2005 Discounted Registration Deadline: November 4 2005 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13-AI066893-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Pathogen-Host Standoff: Persistent and Latent Infection

joint with Determinants of Host Resistance, Susceptibility or Immunopathology to Pathogens: Integrating Knowledge from Experimental Models to Human Disease

Organizer(s): Edward S. Mocarski Jr. and JoAnne L. Flynn

Date: January 05 - 10, 2006
Location: Keystone Resort, Keystone, CO, USA

Supported by the Burroughs Wellcome Fund

Summary of Meeting:

Exciting current research: - Common host immune mechanisms interface with a variety of microbes. - Immune modulation and evasion strategies still expanding in scope. - Immune response does not equal clearance; protective immunity still being defined. Problems in the field: - How to effectively enhance an immune response to eliminate an organism that has evolved to be persistent in the host. - How to integrate information about the immune response to acute disease in the context of chronic and latent infections. - How to categorize the persistent or latent state of a pathogen, and determine the genetic components that contribute to latency. - Bring together scientists from different fields to think about the concepts of latency and persistence, and share ideas from different fields. Goals: - Understand common themes in latent microbial infections, regardless of whether a virus, bacterium, parasite, worm, or fungus. - Contrast differences in immunologic memory during acute, chronic and latent infection (important in design of vaccine or treatment strategies). - Understand common immune mechanisms controlling latent or persistent microbes. - Identify strategies by which pathogens escape detection or elimination by the immune system, and design strategies to circumvent these pathogens (vaccine or drug development).

Scholarship Deadline: September 13 2005

Discounted Abstract Deadline: September 13 2005

Abstract Deadline: October 3 2005

Discounted Registration Deadline: November 4 2005

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13-AI066893-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Thursday, January 05 \| 3:00PM - 7:30PM Registration Room: Shavano Peak Foyer
Thursday, January 05 \| 6:30PM - 7:30PM Refreshments Room: Shavano Peak Foyer
Thursday, January 05 \| 7:30PM - 8:30PM Keynote Address Room: Shavano Peak Speaker 1 of 1 Francis V. Chisari, The Scripps Research Institute, USA Robust Hepatitis C Virus Infection in Vitro: Coevolution of Virus and Host
Friday, January 06 \| 7:00AM - 8:00AM Breakfast Room: Torreys 1-4
Friday, January 06 \| 8:00AM - 11:00AM Cell-Intrinsic Responses to Pathogens Room: Shavano Peak Speaker 1 of 5 John Hiscott, Vaccine & Gene Therapy Institute of Florida, USA Regulation of Antiviral Defense and Apoptosis by the IRF Transcription Factors
Friday, January 06 \| 8:00AM - 11:00AM Cell-Intrinsic Responses to Pathogens Room: Shavano Peak Speaker 2 of 5 J. Marie Hardwick, Johns Hopkins University Schools of Public Health and Medicine, USA Programmed Cell Death in Viral Pathogenesis
Friday, January 06 \| 8:00AM - 11:00AM Cell-Intrinsic Responses to Pathogens Room: Shavano Peak Speaker 3 of 5 * Edward S. Mocarski, Emory University, USA Cell Intrinsic Responses in Cytomegalovirus Replication and Pathogenesis
Friday, January 06 \| 8:00AM - 11:00AM Cell-Intrinsic Responses to Pathogens Room: Shavano Peak Speaker 4 of 5 Kathryn E. Foulds, NIAID, National Institutes of Health, USA Short Talk: IL-10 is Required for Optimal CD8 T Cell Memory following Listeria monocytogenes Infection
Friday, January 06 \| 8:00AM - 11:00AM Cell-Intrinsic Responses to Pathogens Room: Shavano Peak Speaker 5 of 5 Dorian B. McGavern, NINDS, National Institutes of Health, USA Short Talk: Adoptive Immunotherapy Induces Dendritic Cell Recruitment and Antigen Presentation in the CNS during the Clearance of a Persistent Viral Infection
Friday, January 06 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Friday, January 06 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Friday, January 06 \| 5:00PM - 7:00PM Pathogen Escape from Control Room: Shavano Peak Speaker 1 of 4 Dan R. Littman, HHMI/New York University School of Medicine, USA Roles of Dendritic Cells in Intestinal Immunity and HIV Pathogenesis
Friday, January 06 \| 5:00PM - 7:00PM Pathogen Escape from Control Room: Shavano Peak Speaker 2 of 4 Christopher L. Karp, Bill & Melinda Gates Foundation, USA Regulation of TLR Signaling and the Host Interface with Pathogens and Danger
Friday, January 06 \| 5:00PM - 7:00PM Pathogen Escape from Control Room: Shavano Peak Speaker 3 of 4 * Alan G. Barbour, University of California, Irvine, USA Antigenic Variation by Borrelia Species in Natural Hosts
Friday, January 06 \| 5:00PM - 7:00PM Pathogen Escape from Control Room: Shavano Peak Speaker 4 of 4 Chris A. Benedict, La Jolla Institute for Allergy and Immunology, USA Short Talk: Herpesvirus Targeting of the HVEM-BTLA Cosignaling System
Friday, January 06 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys 1-4
Saturday, January 07 \| 7:00AM - 8:00AM Breakfast Room: Torreys 1-4
Saturday, January 07 \| 8:00AM - 11:00AM Patterns of Pathogen Growth and Behavior Room: Shavano Peak Speaker 1 of 5 Diane E. Griffin, Johns Hopkins Bloomberg School of Public Health, USA Measles: Virus Clearance and Protective Immunity
Saturday, January 07 \| 8:00AM - 11:00AM Patterns of Pathogen Growth and Behavior Room: Shavano Peak Speaker 2 of 5 Herbert (Skip) W. Virgin, Vir Biotechnology, USA The Host:Herpesvirus Standoff: Good News from the Front of an Ancient Battle
Saturday, January 07 \| 8:00AM - 11:00AM Patterns of Pathogen Growth and Behavior Room: Shavano Peak Speaker 3 of 5 * JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA Dynamic Immune Responses in Tuberculosis
Saturday, January 07 \| 8:00AM - 11:00AM Patterns of Pathogen Growth and Behavior Room: Shavano Peak Speaker 4 of 5 Jennifer Philips, Washington University School of Medicine, USA Short Talk: Genome-Wide RNAi Screens in Drosophila Identify Host Factors Involved in Mycobacterial Infection
Saturday, January 07 \| 8:00AM - 11:00AM Patterns of Pathogen Growth and Behavior Room: Shavano Peak Speaker 5 of 5 Linda F. van Dyk, University of Colorado Health Sciences Center, USA Short Talk: Interactions of a Viral Cyclin and a Host Inhibitor in Control of gammaherpesvirus Infection
Saturday, January 07 \| 8:00AM - 11:15AM Immune Mechanisms for Protection versus Progression: From Mo use Models to Human Disease This session is from Determinants of Host Resistanc Room: Red Cloud Speaker 1 of 6 * Anne O'Garra, Francis Crick Institute, UK Development of Suppressive or Protective Immune Responses to Pathogens: Implications for Control of TB
Saturday, January 07 \| 8:00AM - 11:15AM Immune Mechanisms for Protection versus Progression: From Mo use Models to Human Disease This session is from Determinants of Host Resistanc Room: Red Cloud Speaker 2 of 6 Alan Sher, NIAID, National Institutes of Health, USA TLR Co-Operation in Host Defense against Intracellular Pathogens
Saturday, January 07 \| 8:00AM - 11:15AM Immune Mechanisms for Protection versus Progression: From Mo use Models to Human Disease This session is from Determinants of Host Resistanc Room: Red Cloud Speaker 3 of 6 Anne E. Goldfeld, Children's Hospital Boston, Harvard Medical School, USA TB and HIV Pathogenesis: From the Field to the Bedside
Saturday, January 07 \| 8:00AM - 11:15AM Immune Mechanisms for Protection versus Progression: From Mo use Models to Human Disease This session is from Determinants of Host Resistanc Room: Red Cloud Speaker 4 of 6 Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA Immune Control and Immune Failure in HIV infection
Saturday, January 07 \| 8:00AM - 11:15AM Immune Mechanisms for Protection versus Progression: From Mo use Models to Human Disease This session is from Determinants of Host Resistanc Room: Red Cloud Speaker 5 of 6 Andrea M. Cooper, University of Leicester, UK Short Talk: IL-23 is Required for Vaccine-Induced Protection Against Aerosol-Delivered Mycobacterium Tuberculosis infection
Saturday, January 07 \| 8:00AM - 11:15AM Immune Mechanisms for Protection versus Progression: From Mo use Models to Human Disease This session is from Determinants of Host Resistanc Room: Red Cloud Speaker 6 of 6 Jay K. Kolls, Tulane School of Medicine, USA Short Talk: IL-23/IL-17: Roles in Host Defense Against Acute Extracellular Gram Negative Bacteria and Immnuopathology in Chronic Bacterial Infection
Saturday, January 07 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Saturday, January 07 \| 11:00AM - 1:00PM Poster Setup Room: Torreys 1-4
Saturday, January 07 \| 1:00PM - 10:00PM Poster Viewing Room: Torreys 1-4
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 9 * Charles R.M. Bangham, Imperial College Department of Medicine, UK
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 9 Victoria Olivia Kasprowicz, Harvard Medical School, USA Small Virus – Big Response: Divergent CD4+ and CD8+ T Cell Immune Responses After Acute Parvovirus B19 Infection
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 9 * George Kassiotis, Francis Crick Institute, UK Memory T Helper Cell Heterogeneity
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 9 Anthony A. Ryan, Centenary Institute of Cancer Medicine & Cell Biology, Australia Targeting Antigen Presenting Cells as a Strategy to Improve Protective Immunity Against Tuberculosis
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 5 of 9 Anuratha Sakthianandeswaren, Walter and Eliza Hall Institute of Medical Research, Australia The Wound Repair Response Controls Outcome to Murine Cutaneous Leishmaniasis
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 6 of 9 Thomas J. Scriba, University of Cape Town, South Africa Optimized HLA Class II Tetramer Staining Allows Ultra-Sensitive Detection and Phenotyping of Antigen-Specific CD4+ T Cells
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 7 of 9 Felix Yarovinsky, University of Rochester Medical Center, USA Toll-Like Receptor 11 Recognition Renders Toxoplasma Profilin into an Immunodominant Antigen in the CD4+T Cell Response to the Parasite
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 8 of 9 Karina Yusim, Los Alamos National Laboratory, USA Rational HIV and Hepatitis C Vaccine Design to Optimize T Cell Responses
Saturday, January 07 \| 2:30PM - 4:30PM Workshop 1: Host Susceptibility and Resistance Mechanisms in Mouse and Man This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 9 of 9 Shane Crotty, La Jolla Institute for Immunology, USA SAP Deficiency Triggers CD8-Mediated Immunopathology and Hypogammaglobulinemia in a Non-Herpesvirus Chronic Infection
Saturday, January 07 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Saturday, January 07 \| 5:00PM - 7:00PM Regulation of Innate and Adaptive Immunity Room: Shavano Peak Speaker 1 of 4 E. John Wherry, University of Pennsylvania, USA Maintenance properties of virus specific CD8 T cells during chronic infection
Saturday, January 07 \| 5:00PM - 7:00PM Regulation of Innate and Adaptive Immunity Room: Shavano Peak Speaker 2 of 4 * Yasmine Belkaid, NIAID, National Institutes of Health, USA Regulatory T Cells and Parasite Persistence
Saturday, January 07 \| 5:00PM - 7:00PM Regulation of Innate and Adaptive Immunity Room: Shavano Peak Speaker 3 of 4 Christine A. Biron, Brown University, USA Integrating and Shaping Early Events in Immunity to Viral Infections
Saturday, January 07 \| 5:00PM - 7:00PM Regulation of Innate and Adaptive Immunity Room: Shavano Peak Speaker 4 of 4 Jason A. Skinner, University of Pennsylvania School of Medicine, USA Short Talk: Bordetella bronchiseptica Modulates Dendritic Cell Function and Host Immunity to Establish Persistent Infection
Saturday, January 07 \| 5:00PM - 7:00PM Determinants of Chronicity in Viral Infection This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 4 Mark B. Feinberg, IAVI International AIDS Vaccine Initiative, USA Host-Virus Relationships in Nonpathogenic SIV Infections
Saturday, January 07 \| 5:00PM - 7:00PM Determinants of Chronicity in Viral Infection This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 4 * David I. Watkins, University of Miami, USA Defining a Protective Immune Response: In vivo Depletion of CD8 Lymphocytes in Elite SIV Controllers
Saturday, January 07 \| 5:00PM - 7:00PM Determinants of Chronicity in Viral Infection This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 4 Philip J. Goulder, University of Oxford, UK Immune Selection Pressure, Viral Evolution and Host Evolution in HIV Infection
Saturday, January 07 \| 5:00PM - 7:00PM Determinants of Chronicity in Viral Infection This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 4 Charles R.M. Bangham, Imperial College Department of Medicine, UK Short Talk: Immune Containment and Cell to Cell Spread of the Human Leukemia Virus HTLV-1
Saturday, January 07 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys 1-4
Saturday, January 07 \| 7:30PM - 10:00PM Poster Session 1 Room: Torreys 1-4
Sunday, January 08 \| 7:00AM - 8:00AM Breakfast Room: Torreys 1-4
Sunday, January 08 \| 8:00AM - 11:15AM Pattern Recognition in Persistent and Latent Infection (Join t) Room: Shavano/Red Cloud Speaker 1 of 6 Caetano Reis e Sousa, Francis Crick Institute, UK Pattern Recognition Pathways in Dendritic Cells
Sunday, January 08 \| 8:00AM - 11:15AM Pattern Recognition in Persistent and Latent Infection (Join t) Room: Shavano/Red Cloud Speaker 2 of 6 Eric G. Pamer, University of Chicago, USA Immune Response to Aspergillus fumigatus Infection
Sunday, January 08 \| 8:00AM - 11:15AM Pattern Recognition in Persistent and Latent Infection (Join t) Room: Shavano/Red Cloud Speaker 3 of 6 * Michael B. Brenner, Harvard Medical School, USA Lipid Antigen Presentation by CD1 Results in Rapid T Cell Activation As Well As Adaptive Immunity
Sunday, January 08 \| 8:00AM - 11:15AM Pattern Recognition in Persistent and Latent Infection (Join t) Room: Shavano/Red Cloud Speaker 4 of 6 Edward J. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany Helminth Control of Dendritic Cell Function
Sunday, January 08 \| 8:00AM - 11:15AM Pattern Recognition in Persistent and Latent Infection (Join t) Room: Shavano/Red Cloud Speaker 5 of 6 Weiming Yuan, University of Southern California, USA Short Talk: Immune Evasion of HSV-1 by Down-Regulation of CD1d Expression
Sunday, January 08 \| 8:00AM - 11:15AM Pattern Recognition in Persistent and Latent Infection (Join t) Room: Shavano/Red Cloud Speaker 6 of 6 Helle Bielefeldt-Ohmann, Colorado State University, USA Short Talk: Helicobacter Induced Colon Cancer in Smad3 Deficient Mice: A Synergistic Effect of Dysregulated Epithelial Proliferation and Deficient Regulation of Inflammation?
Sunday, January 08 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Sunday, January 08 \| 11:00AM - 1:00PM Poster Setup Room: Torreys 1-4
Sunday, January 08 \| 1:00PM - 10:00PM Poster Viewing Room: Torreys 1-4
Sunday, January 08 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Sunday, January 08 \| 5:00PM - 7:00PM Challenges of the Intracellular Lifestyle Room: Shavano Peak Speaker 1 of 4 * Daniel A. Portnoy, University of California, Berkeley, USA How Listeria monocytogenes Avoids Killing its Host Cell
Sunday, January 08 \| 5:00PM - 7:00PM Challenges of the Intracellular Lifestyle Room: Shavano Peak Speaker 2 of 4 David G. Russell, Cornell University, USA Mycobacterium Tuberculosis and the Innate Immune Tune
Sunday, January 08 \| 5:00PM - 7:00PM Challenges of the Intracellular Lifestyle Room: Shavano Peak Speaker 3 of 4 Anita Sil, University of California, San Francisco, USA Histoplasma capsulatum Development in Pathogenesis
Sunday, January 08 \| 5:00PM - 7:00PM Challenges of the Intracellular Lifestyle Room: Shavano Peak Speaker 4 of 4 Yun Ling, Brown University, USA Short Talk: Rapid Elimination of Toxoplasma gondii in Primed Macrophages: The Role of IGTP and Lysosomal Fusion
Sunday, January 08 \| 5:00PM - 7:00PM Genetics of Immune Responses to Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 3 * Jean-Laurent Casanova, Rockefeller University, USA A Genetic Dissection of Cytokine-Mediated Immunity to Infection in Humans
Sunday, January 08 \| 5:00PM - 7:00PM Genetics of Immune Responses to Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 3 Richard A. Flavell, HHMI/Yale University School of Medicine, USA Role of Host Innate and Adaptive Immune Response Genes in Resistance to Pathogens in Mouse Models
Sunday, January 08 \| 5:00PM - 7:00PM Genetics of Immune Responses to Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 3 Thomas R. Hawn, University of Washington, USA Short Talk: Polymorphisms in TLR-Pathway Genes are Associated with Signaling Deficiencies and Increased Susceptibility to Tuberculosis
Sunday, January 08 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys 1-4
Sunday, January 08 \| 7:30PM - 10:00PM Poster Session 2 Room: Torreys 1-4
Monday, January 09 \| 7:00AM - 8:00AM Breakfast Room: Torreys 1-4
Monday, January 09 \| 8:00AM - 11:00AM Persistence in the Face of Adaptive Room: Shavano Peak Speaker 1 of 4 Britta C. Urban, University of Oxford, UK Modulation of Dendritic Cell Funtion by Plasmodium Falciparum-Infected Erythrocytes: The Malaria-T Cell Standoff
Monday, January 09 \| 8:00AM - 11:00AM Persistence in the Face of Adaptive Room: Shavano Peak Speaker 2 of 4 Kevin B. Urdahl, Seattle Children's Research Institute, USA Location and Function of Foxp3-Expressing T Regulatory Cells during Tuberculosis
Monday, January 09 \| 8:00AM - 11:00AM Persistence in the Face of Adaptive Room: Shavano Peak Speaker 3 of 4 * Michael Starnbach, Harvard Medical School, USA Cellular Immune Control of Persistent Bacterial Infection
Monday, January 09 \| 8:00AM - 11:00AM Persistence in the Face of Adaptive Room: Shavano Peak Speaker 4 of 4 David M. Lewinsohn, Oregon Health & Science University, USA Short Talk: HLA-E Restricted Human CD8+ T Cells Recognize Post-Translationally Modified HspX from Mycobacterium Tuberculosis
Monday, January 09 \| 8:00AM - 11:15AM Pathogen Manipulation of the Host Immune Response; For Bette r or For Worse This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 6 Carl F. Nathan, Weill Cornell Medical College, USA Host-Pathogen Relationship as Competitive Genomic Immunological Challenges of TB
Monday, January 09 \| 8:00AM - 11:15AM Pathogen Manipulation of the Host Immune Response; For Bette r or For Worse This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 6 Philippe J. Sansonetti, Institut Pasteur, France Rupture, Invasion and Inflammatory Destruction of the Intestinal Epithelium by Shigella: The Yin and the Yang of Innate Immunity
Monday, January 09 \| 8:00AM - 11:15AM Pathogen Manipulation of the Host Immune Response; For Bette r or For Worse This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 6 Françoise Barré-Sinoussi, Institut Pasteur, France Lessons from Early Responses to Nonpathogenic SIV Infection in African Green Monkeys
Monday, January 09 \| 8:00AM - 11:15AM Pathogen Manipulation of the Host Immune Response; For Bette r or For Worse This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 6 * Carl F. Ware, Sanford-Burnham Medical Research Institute, USA Virus Modulation of the TNF Superfamily
Monday, January 09 \| 8:00AM - 11:15AM Pathogen Manipulation of the Host Immune Response; For Bette r or For Worse This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 5 of 6 Javier A. Carrero, Washington University, USA Short Talk: Role of Listeriolysin O in the in vivo Virulence of Listeria Monocytogenes
Monday, January 09 \| 8:00AM - 11:15AM Pathogen Manipulation of the Host Immune Response; For Bette r or For Worse This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 6 of 6 John E. Connolly, Parker Institute for Cancer Immunotherapy, USA Short Talk: Respiratory Syncytial Virus Subverts the Immune Response through the Induction of Tolerogenic Myeloid Dendritic Cells
Monday, January 09 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 9 * Andrea M. Cooper, University of Leicester, UK
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 9 * Paul Klenerman, University of Oxford, UK
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 9 Sara R. Klucking, Emory University, USA Inefficient Production of IFNa by pDCs is Involved in the Limited Immune Activation and AIDS-Resistance in Naturally SIV-Infected SMs.
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 9 Alasdair J. Leslie, Kwazulu Natal Research Institute for HIV and TB, South Africa The Biological Relevance of Supertypes in HIV-1 Infection
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 5 of 9 Emily J. Lyons, Wellcome Trust Centre for Human Genetics, UK Consanguinity and Susceptibility to Human Infectious Diseases
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 6 of 9 Amarendra Pegu, NIAID, National Institutes of Health, USA Interactions between Mycobacterium Tuberculosis and the Lymphatic Endothelium
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 7 of 9 Shahin Ranjbar, Immune Disease Institute, USA Tat from HIV-1 Subtype E Selectively Inhibits TNF Gene Expression via Interference with Chromatin Remodeling of the TNF Locus
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 8 of 9 Thuong T. T. Nguyen, Oxford University Clinical Research Unit, Vietnam A Polymorphism in Human TLR2 is Associated with Increased Susceptibility to Tuberculous Meningitis
Monday, January 09 \| 2:30PM - 4:30PM Workshop 2: Shared Mechanisms of Pathogenesis in Mice and Me n This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 9 of 9 Esther Van De Vosse, Leiden University Medical Center, Netherlands Host Genetics of Salmonella (para-) Typhi Infection
Monday, January 09 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Monday, January 09 \| 5:00PM - 7:00PM Successful Persistence and Latency Themes Room: Shavano Peak Speaker 1 of 4 Louis J. Picker, Oregon Health & Science University, USA Immunobiology of Cmv Infection in Rhesus Macaques
Monday, January 09 \| 5:00PM - 7:00PM Successful Persistence and Latency Themes Room: Shavano Peak Speaker 2 of 4 Christopher M. Walker, Nationwide Children's Hospital, USA Protection Against Hepatitis C Virus Infection
Monday, January 09 \| 5:00PM - 7:00PM Successful Persistence and Latency Themes Room: Shavano Peak Speaker 3 of 4 * David Thorley-Lawson, Tufts University School of Medicine, USA Persistence of the Epstein-Barr Virus and the Origins of Associated Lymphomas for Real and in Virtual Reality.
Monday, January 09 \| 5:00PM - 7:00PM Successful Persistence and Latency Themes Room: Shavano Peak Speaker 4 of 4 Rajeev Mani Nepal, Ohio State University, USA Short Talk: DM, but not Cathepsin L, is Required to Control an Aerosol Infection with Mycobacterium tuberculosis
Monday, January 09 \| 5:00PM - 7:00PM Diverse Immune Cells Combat Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 4 * Stefan H. E. Kaufmann, Max Planck Institute for Infection Biology, Berlin, Germany Interpretation of the Natural Host-Pathogen Crosstalk Provides Guidelines for Vaccine Design against Tuberculosis
Monday, January 09 \| 5:00PM - 7:00PM Diverse Immune Cells Combat Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 4 David L. Sacks, NIAID, National Institutes of Health, USA Immunology of Non-Curing Forms of Leishmaniasis in Mice and Humans
Monday, January 09 \| 5:00PM - 7:00PM Diverse Immune Cells Combat Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 4 Paul Klenerman, University of Oxford, UK HCV immunology – Tracking T cells in viral persistence
Monday, January 09 \| 5:00PM - 7:00PM Diverse Immune Cells Combat Pathogens This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 4 David G. Brooks, Princess Margaret Cancer Center, Canada Short Talk: Functional Re-Programming of Antiviral T Cells: Prevention of Clonal Deletion and Restoration of T Cell Activity during Persistent Viral Infection
Monday, January 09 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys 1-4
Monday, January 09 \| 8:00PM - 11:00PM Entertainment Room: Torreys 1-4
Monday, January 09 \| 8:00PM - 11:00PM Cash Bar Room: Torreys 1-4
Tuesday, January 10 \| 8:00AM - 11:00AM Type-1 IFN: Friend or Foe This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 5 * Giorgio Trinchieri, NCI, National Institutes of Health, USA IFN-alpha in the Fight Against Infectious Diseases
Tuesday, January 10 \| 8:00AM - 11:00AM Type-1 IFN: Friend or Foe This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 5 Malik Peiris, University of Hong Kong, Hong Kong SARS, Avian Influenza and Innate Immune Responses
Tuesday, January 10 \| 8:00AM - 11:00AM Type-1 IFN: Friend or Foe This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 5 Emil R. Unanue, Washington University School of Medicine, USA Lymphocyte Apoptosis in Infection: Molecular Basis and Biology
Tuesday, January 10 \| 8:00AM - 11:00AM Type-1 IFN: Friend or Foe This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 5 Richard Pine, Public Health Research Institute, USA Short Talk: Autocrin/Paracrine Responses to IFNalpha/beta Produced by Mtb Infected Macrophages
Tuesday, January 10 \| 8:00AM - 11:00AM Type-1 IFN: Friend or Foe This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 5 of 5 Steven W. Dow, Colorado State University, USA Short Talk: Deleterious Role for Type I Interferons in Systemic Yersinia pestis Infections
Tuesday, January 10 \| 10:26AM - 10:26AM Departure *Session Chair.
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 1 of 7 Ian R. Humphreys, Cardiff University, UK OX40 Limits CMV Persistence in an Organ-Specific Manner that is Dependent on Distinct T Cell Subsets
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 2 of 7 John J. Osterholzer, Ann Arbor VA Hospital and University of Michigan, USA CCR2 Mediates the Recruitment of Myeloid and Plasmacytoid Dendritic Cells to the Lungs of Mice Infected with Crypotoccus neoformans: Implications for Th1/Th2 Polarization
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 3 of 7 Michael H. Shaw, Brown University, USA Negative Feedback Regulation of Local Th1 Immunity by IFN-gamma Induced ICOSL-Dependent Reactivation of IL-10
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 4 of 7 * Merilyn H. Hibma, University of Otago, New Zealand Human Papillomavirus Type 16 E6 Protein Reduces Cell Surface E-Cadherin: A Mechanism for Viral Immune Evasion
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 5 of 7 * Jean Langhorne, Francis Crick Institute, UK Activation of CD4 T Cells by Different Populations of Splenic Dendritic Cells In Vivo in a Model of Malaria
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 6 of 7 Shabaana A. Khader, Washington University School of Medicine, USA IL-12p40 Homodimer is Required for Dendritic Cell Migration and T Cell Priming Following Mycobacterium Tuberculosis Infection of the Lung
Tuesday, January 10 \| 2:30PM - 4:30PM Workshop 3: Immunoregulation and Immune Evasion in Infectiou s Diseases This session is from Determinants of Host Resistanc Room: Red Cloud Peak Speaker 7 of 7 Bo Wu, Stanford University, USA Measurment of FOXP3 MRNA Distiguishes Active from Latent Mtb Infections
Tuesday, January 10 \| 5:00PM - 6:20PM Influenza Still Plagues us After A Century - Implications fo r Host Responses to New and Emerging Viruses such as Severe Acute Respiratory Syndrome (SARS) This session is from Determinants of Host Resistanc Room: Crestone Peak Speaker 1 of 2 * Kanta Subbarao, WHO Collaborating Centre for Reference and Research on Influenza, Australia Host Responses to Avian Influenza and SARS: Implications for Vaccine Development
Tuesday, January 10 \| 5:00PM - 6:20PM Influenza Still Plagues us After A Century - Implications fo r Host Responses to New and Emerging Viruses such as Severe Acute Respiratory Syndrome (SARS) This session is from Determinants of Host Resistanc Room: Crestone Peak Speaker 2 of 2 Herbert (Skip) W. Virgin, Vir Biotechnology, USA Innate and Acquired Immunity to a Novel Norovirus in Mice
Tuesday, January 10 \| 6:20PM - 7:00PM Future of Research in the Immunology of Infectious Disease This session is from Determinants of Host Resistanc Room: Crestone Peak Speaker 1 of 1 Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA Blood Leukocyte Transcriptional Fingerprints as Novel Diagnostic and Prognostic Indicators