Web Desc
Adipogenesis, Obesity and Inflammation
joint with Diabetes Mellitus and the Control of Cellular Energy Metabolism
Organizer(s): Philipp E. Scherer and Steven E. Shoelson
Date: January 21 - 26, 2006
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada
Part of the Translational Medicine Series, Sponsored by Pfizer Global Research & Development
Summary of Meeting:
The worldwide epidemic in obesity has brought with it dramatic increases in the prevalence of co-morbid, chronic conditions including insulin resistance, type 2 diabetes, the metabolic syndrome, and atherosclerosis. The rapid rise in these major public health problems underscores a growing need to understand the physiological and pathological bases of feeding and obesity, and the pathophysiological links between obesity and these associated morbidities. This meeting focuses on recent advances being made in our understanding of the molecular basis of feeding and nutrient storage and on the molecular consequences of obesity in terms of promoting risk of developing diabetes and cardiovascular disease. Specific topics related to potential causes of obesity include: I) Central regulation of feeding and adiposity, II) Genetic defects leading to obesity, and III) Adipogenesis and adipocyte differentiation. Topics related to the consequences of obesity include: I) Adipokines and other products of adipocytes, II) Inflammation in fat and other organs and the recruitment and involvement of macrophages, III) Accumulation of lipids and adipocytes in other organs, IV) Etiology of the metabolic syndrome and association with atherosclerosis. Special attention will be given to translational insights that highlight some of the clinical implications of excess storage of adipose tissue. Some sessions will be held jointly with the “Diabetes Mellitus and the control of Cellular Energy Metabolism” meeting that will effectively complement the obesity meeting.
Scholarship Deadline: September 21 2005
Discounted Abstract Deadline: September 21 2005
Abstract Deadline: October 13 2005
Discounted Registration Deadline: November 21 2005
We gratefully acknowledge additional support for this conference from:
ALPCO DiagnosticsCell Signaling Technology, Inc.Novartis Institutes for BioMedical ResearchPfizer Global Research & Development
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1 R13 DK072700-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Saturday, January 21 | 3:00PM - 7:30PM
Registration
Room: BC Foyer


Saturday, January 21 | 6:30PM - 7:30PM
Refreshments
Room: BC Foyer


Saturday, January 21 | 7:30PM - 8:30PM
Keynote Address (Joint)
Room: British Columbia Ballroom

Speaker 1 of 1
Christopher B. Newgard, Duke University Medical Center, USA
Comprehensive Metabolic Profiling for Understanding of Obesity and Diabetes Mechanisms

Sunday, January 22 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Sunday, January 22 | 8:00AM - 11:15AM
Lipid and Carbohydrate Metabolism and Energy Homeostasis (Jo
int)

Room: British Columbia Ballroom

Speaker 1 of 6
* Bei B. Zhang, Pfizer Inc., USA
Short Talk: Role of DPP-4 Inhibitors in Glycemia Control and Beta-cell Preservation


Sunday, January 22 | 8:00AM - 11:15AM
Lipid and Carbohydrate Metabolism and Energy Homeostasis (Jo
int)

Room: British Columbia Ballroom

Speaker 2 of 6
Bruce M. Spiegelman, Harvard Medical School, USA
The Transcriptional Basis of Energy Homeostasis

Sunday, January 22 | 8:00AM - 11:15AM
Lipid and Carbohydrate Metabolism and Energy Homeostasis (Jo
int)

Room: British Columbia Ballroom

Speaker 3 of 6
Richard N. Bergman, Cedars-Sinai Medical Center, USA
Pathophysiology of the Metabolic Syndrome

Sunday, January 22 | 8:00AM - 11:15AM
Lipid and Carbohydrate Metabolism and Energy Homeostasis (Jo
int)

Room: British Columbia Ballroom

Speaker 4 of 6
Christopher K. Glass, University of California, San Diego, USA
Anti-inflammatory and Antidiabetic Roles of PPARgamma in Macrophages

Sunday, January 22 | 8:00AM - 11:15AM
Lipid and Carbohydrate Metabolism and Energy Homeostasis (Jo
int)

Room: British Columbia Ballroom

Speaker 5 of 6
Domenico Accili, Columbia University, USA
Forkhead Proteins in Diabetes and Obesity

Sunday, January 22 | 8:00AM - 11:15AM
Lipid and Carbohydrate Metabolism and Energy Homeostasis (Jo
int)

Room: British Columbia Ballroom

Speaker 6 of 6
Rudolf Zechner, University of Graz, Austria
Short Talk: ATGL: A Newly Discovered Rate-limiting Enzyme for the Lipolysis of Stored Fat

Sunday, January 22 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Sunday, January 22 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Sunday, January 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 1 of 7
* Philipp E. Scherer, University of Texas Southwestern Medical Center, USA

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 2 of 7
Philip G. McTernan, University of Warwick, UK
Sub-clinical Inflammation in Type 2 Diabetes: Effect of Endotoxemia on Initiating the Inflammatory Cascade in Human Adipose Tissue

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 3 of 7
Robert M. O'Doherty, University of Pittsburgh, USA
Toll-like Receptor-4 Mediates Palmitate and Lipopolysaccaride Activation of the IKK/IkappaB/NFkappaB Pathway in Skeletal Muscle

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 4 of 7
Carl W. Porter, Roswell Park Cancer Institute, USA
Spermidine/spermine N1-Acetyltransferase as a Effector of Fat Homeostasis

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 5 of 7
Ofer Reizes, Cleveland Clinic Foundation, USA
Weight Reduced Diet Induced Obese Mice Have Small Fat Cells, Improved Glucose Clearance, and are Leptin Sensitive

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 6 of 7
Ann V. Hertzel, University of Minnesota, USA
Lipid Metabolism and Adipokine Levels in Fatty Acid Binding Protein Null and Transgenic Mice

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
Room: British Columbia Ballroom

Speaker 7 of 7
Joel P. Berger, Takeda Pharmaceuticals International, USA
A Novel Selective Peroxisome Proliferator-Activator Receptor-gamma Modulator is a Robust Insulin Sensitizer with Diminished Adverse Cardiovascular Effects

Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
This session is from Diabetes Mellitus

Speaker 1 of 6
* Silvia Corvera, University of Massachusetts Medical School, USA


Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
This session is from Diabetes Mellitus

Speaker 2 of 6
Takehide Ogihara, Fukushima Medical University, Japan
Role of eNOS in Beta Cell Regeneration after Bone Marrow Transplantation in STZ-Diabetic Mouse Models


Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
This session is from Diabetes Mellitus

Speaker 3 of 6
Su-Jin Kim, University of British Columbia, Canada
Quantitative Post-Transplant Islet Imaging In Vivo Using Micro Positron Emission Tomography (PET) for the Determination of Islet Graft Survival


Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
This session is from Diabetes Mellitus

Speaker 4 of 6
Haruhisa Iguchi, National Cancer Center Research Institute, Japan
SOX6 Attenuates Glucose Stimulated Insulin Secretion and Acts as a Co-Repressor for PDX1


Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
This session is from Diabetes Mellitus

Speaker 5 of 6
Dinesh C. Gautam, NIDDK, National Institutes of Health, USA
A Critical Role for Beta-Cell M3 Muscarinic Acetylcholine Receptors in Regulating Insulin Release and Blood Glucose Homeostasis


Sunday, January 22 | 2:30PM - 4:30PM
Hot Topics I
This session is from Diabetes Mellitus

Speaker 6 of 6
Mirela Delibegovic, University of Aberdeen, UK
Dessecting the Tissue Specific Roles of Protein-Tyrosine Phosphatase 1B (PTP1B)


Sunday, January 22 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Sunday, January 22 | 5:00PM - 7:00PM
Molecular Mechanism of Adipogenesis and Adipokines
Room: Columbia Ballroom

Speaker 1 of 5
* Domenico Accili, Columbia University, USA

Sunday, January 22 | 5:00PM - 7:00PM
Molecular Mechanism of Adipogenesis and Adipokines
Room: Columbia Ballroom

Speaker 2 of 5
Stephen R. Farmer, Boston University School of Medicine, USA
Transcriptional Control of Adipocyte Formation and Function

Sunday, January 22 | 5:00PM - 7:00PM
Molecular Mechanism of Adipogenesis and Adipokines
Room: Columbia Ballroom

Speaker 3 of 5
M. Daniel Lane, Johns Hopkins University, USA
Role of the C/EBPs in Adipogenesis

Sunday, January 22 | 5:00PM - 7:00PM
Molecular Mechanism of Adipogenesis and Adipokines
Room: Columbia Ballroom

Speaker 4 of 5
Ormond A. MacDougald, University of Michigan, USA
Role of Wnt Signaling in Development of Adipose Tissues and Bone

Sunday, January 22 | 5:00PM - 7:00PM
Molecular Mechanism of Adipogenesis and Adipokines
Room: Columbia Ballroom

Speaker 5 of 5
Shigeki Shimba, Nihon University, Japan
Short Talk: BMAL1, a Master Component of the Molecular Clock, Regulates Adipogenesis and IL6 Expression

Sunday, January 22 | 5:00PM - 7:00PM
Mitochondria and Diseases
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 1 of 5
* E. Dale Abel, University of Iowa, Carver College of Medicine, USA
Short Talk: Regulation of Myocardial Mitochondrial Oxidative Capacity by PI3-Kinase and Akt


Sunday, January 22 | 5:00PM - 7:00PM
Mitochondria and Diseases
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 2 of 5
Michael A. Brownlee, Albert Einstein College of Medicine, USA
Mitochondrial Disfunction, Methylhlyoxal Generation and Diabetic Complications: A Novel Mechanism for Regulation of Gene Expression of Hyperglycemra


Sunday, January 22 | 5:00PM - 7:00PM
Mitochondria and Diseases
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 3 of 5
Nils-Goran Larsson, Karolinska Institutet, Sweden
The Role of Mitochondrial Dysfunction in Aging and Diabetes


Sunday, January 22 | 5:00PM - 7:00PM
Mitochondria and Diseases
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 4 of 5
David E. Kelley, Merck & Co., Inc., USA
Mitochondrial Dysfunction in the Pathogenesis of Insulin Resistance


Sunday, January 22 | 5:00PM - 7:00PM
Mitochondria and Diseases
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 5 of 5
Ingrid A. Dahlman, Karolinska Institutet, Sweden
Short Talk: Downregulation of Electron Transport Genes in Visceral adipose Tissue in Type 2 Diaberes Independantly of Obesity and Possibly Involving Tumor Necrosis Factor alpha


Sunday, January 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Sunday, January 22 | 7:30PM - 10:00PM
Poster Session 1
Room: Pacific Ballroom


Monday, January 23 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Monday, January 23 | 8:00AM - 11:15AM
Regulators of Obesity and Inflammation
Room: Columbia Ballroom

Speaker 1 of 6
* Mark A. Febbraio, Monash Institute of Pharmaceutical Sciences, Australia
Short Talk: HSP 72 Protects against Diet-Induced Insulin Resistance by Blocking JNK Phosphorylation

Monday, January 23 | 8:00AM - 11:15AM
Regulators of Obesity and Inflammation
Room: Columbia Ballroom

Speaker 2 of 6
Michael Karin, University of California, San Diego, USA
IKK/NF-kappaB Activation Pathway

Monday, January 23 | 8:00AM - 11:15AM
Regulators of Obesity and Inflammation
Room: Columbia Ballroom

Speaker 3 of 6
Gökhan S. Hotamisligil, Harvard School of Public Health, USA
Integration of Stress Signals in the Endoplasmic Reticulum in Obesity and Diabetes

Monday, January 23 | 8:00AM - 11:15AM
Regulators of Obesity and Inflammation
Room: Columbia Ballroom

Speaker 4 of 6
Anthony W. Ferrante, Columbia University, USA
Adipose Tissue Inflammation and Macrophages

Monday, January 23 | 8:00AM - 11:15AM
Regulators of Obesity and Inflammation
Room: Columbia Ballroom

Speaker 5 of 6
Bente Klarlund Pedersen, University of Copenhagen, Denmark
Exercise and IL-6 action

Monday, January 23 | 8:00AM - 11:15AM
Regulators of Obesity and Inflammation
Room: Columbia Ballroom

Speaker 6 of 6
Peter Cornelius, Systamedic, USA
Short Talk: Resistance of CCR2-/- Mice to Diet-Induced Obesity

Monday, January 23 | 8:00AM - 11:15AM
Organelle Biogenesis and Energy Control
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 1 of 6
* Sheila Collins, Vanderbilt University Medical Center, USA
Short Talk: Signaling Networks Fueling Mitochondrial Metabolism in Fat


Monday, January 23 | 8:00AM - 11:15AM
Organelle Biogenesis and Energy Control
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 2 of 6
Tracey A. Rouault, NICHD, National Institutes of Health, USA
The Role of Iron Regulatory Proteins in Mammalian Iron Metabolism and Neurodegeneration


Monday, January 23 | 8:00AM - 11:15AM
Organelle Biogenesis and Energy Control
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 3 of 6
Daniel P. Kelly, University of Pennsylvania, USA
Mitochondrial Adaptation and Maladaptin in Cardiac and Skeletal Muscle


Monday, January 23 | 8:00AM - 11:15AM
Organelle Biogenesis and Energy Control
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 4 of 6
Janet M. Shaw, University of Utah, USA
Mitochondrial Dynamics and Function in Eukaryotic Cells


Monday, January 23 | 8:00AM - 11:15AM
Organelle Biogenesis and Energy Control
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 5 of 6
Mary-Elizabeth Patti, Joslin Diabetes Center, USA
The Mitochondrial Hypothesis and Diabetes Pathogenesis: A Genomics Perspective


Monday, January 23 | 8:00AM - 11:15AM
Organelle Biogenesis and Energy Control
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 6 of 6
Carles Lerin, Hospital Sant Joan de Deu, Spain
Short Talk: Transcriptional Regulation of Glucose Metabolism through PGC-1alpha Acetylation by the GCN5 Acetyl Transferase Complex


Monday, January 23 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Monday, January 23 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Monday, January 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Monday, January 23 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Monday, January 23 | 5:00PM - 7:00PM
Cellular Responses to Cytokines (Joint)
Room: British Columbia Ballroom

Speaker 1 of 4
* Randal J. Kaufman, Sanford-Burnham Medical Research Institute, USA
Stress in the Endoplasmic Reticulum Activates an Acute Inflammatory Response

Monday, January 23 | 5:00PM - 7:00PM
Cellular Responses to Cytokines (Joint)
Room: British Columbia Ballroom

Speaker 2 of 4
Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA
Tissue-specific Effects of Inflammation in Insulin Resistance, Type II Dianetes, and the metabolic Syndrome

Monday, January 23 | 5:00PM - 7:00PM
Cellular Responses to Cytokines (Joint)
Room: British Columbia Ballroom

Speaker 3 of 4
Silvia Corvera, University of Massachusetts Medical School, USA
Cellular Energy Control and Secretion

Monday, January 23 | 5:00PM - 7:00PM
Cellular Responses to Cytokines (Joint)
Room: British Columbia Ballroom

Speaker 4 of 4
Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Secretory Proteins from Adiose Tissue - Significance for Insulin Resistance

Monday, January 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Monday, January 23 | 7:30PM - 10:00PM
Poster Session 2
Room: Pacific Ballroom


Tuesday, January 24 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 1 of 7
* Paul F. Pilch, Boston University School of Medicine, USA

Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 2 of 7
Morris J. Birnbaum, Pfizer Inc., USA
The Regulation of Glucose and Lipid Metabolism by Akt/PKB

Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 3 of 7
Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Novel Adipocyte-secreted Molecule, Retinol Binding Protein 4, and the Metabolic Syndrome

Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 4 of 7
Markus Stoffel, ETH Zürich, Switzerland
Insulin Regulated Transcription Factors

Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 5 of 7
Luciano Rossetti, Merck Research Laboratories, USA
Insulin Signal Transduction in the Hypothalamus

Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 6 of 7
Jacqueline M. Stephens, Louisiana State University, USA
The Regulation of CT-1 and STAT 5A in Adipocytes

Tuesday, January 24 | 8:00AM - 11:15AM
Signal Transduction and Glucose Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 7 of 7
Reuben J. Shaw, The Salk Institute for Biological Studies, USA
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and
Theraputic Effects of Metformin


Tuesday, January 24 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Tuesday, January 24 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Tuesday, January 24 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
Room: British Columbia Ballroom

Speaker 1 of 6
* Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA

Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
Room: British Columbia Ballroom

Speaker 2 of 6
Lisa A. Lesniewski, University of Colorado, Boulder, USA
Macrophage-Specific CAP Gene Deletion Protects Against High Fat Diet-Induced Insulin Resistance

Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
Room: British Columbia Ballroom

Speaker 3 of 6
Carrie E. McCurdy, University of Oregon, USA
Chronic Maternal Overfeeding Leads to Fetal Steatosis and Metabolic Programming in the Non-Human Primate

Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
Room: British Columbia Ballroom

Speaker 4 of 6
Susanna Hofmann, Klinikum der Universitaet Muenchen, Germany
Impaired Lipid Delivery Increases Insulin Sensitivity in Apolipoprotein E Deficient Mice

Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
Room: British Columbia Ballroom

Speaker 5 of 6
Karen Ruschke, Germany
Deficiency of the Neuronal Transcription Factor NSCL-2 Results in an Increased Number of Preadipocytes in WAT

Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
Room: British Columbia Ballroom

Speaker 6 of 6
Robert E. Lewis, University of Nebraska Medical Center, USA
KSR2-/- Mice are Obese and Energy Efficient

Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
This session is from Diabetes Mellitus

Speaker 1 of 6
* † Ann Louise Olson, Oklahoma University Health Sciences Center, USA


Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
This session is from Diabetes Mellitus

Speaker 2 of 6
Nigel Turner, University of New South Wales, Australia
Role of C-Cbl in the Regulating Fatty Acid Oxidation and Energy Metabolism


Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
This session is from Diabetes Mellitus

Speaker 3 of 6
Jun Wada, Okayama University Graduate School of Medicine, Japan
Gene Delivery of Tim44 Reduces Mitochondrial Superoxide Production and Ameliorates Neointimal Proliferation


Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
This session is from Diabetes Mellitus

Speaker 4 of 6
Xiaoyong Yang, Yale University School of Medicine, USA
Phosphatidylinositol Signaling Links Protein O-GlcNAc Modification to Insulin Resistance


Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
This session is from Diabetes Mellitus

Speaker 5 of 6
Sarah L. Gray, University of Northern British Columbia, Canada
Metabolic Characterization of Mice Heterozygous for a Dominant-Negative PPARgamma Mutation


Tuesday, January 24 | 2:30PM - 4:30PM
Hot Topics II
This session is from Diabetes Mellitus

Speaker 6 of 6
Katja A. Lamia, The Scripps Research Institute, USA
Circadian Clocks and Mammalian Energy Homeostasis


Tuesday, January 24 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Tuesday, January 24 | 5:00PM - 7:00PM
Adipose Tissue, Lipids and Diabetes
Room: Columbia Ballroom

Speaker 1 of 4
* Perry E. Bickel, University of Texas Southwestern Medical Center, USA
Short Talk: The Birth of the Lipid Droplet

Tuesday, January 24 | 5:00PM - 7:00PM
Adipose Tissue, Lipids and Diabetes
Room: Columbia Ballroom

Speaker 2 of 4
Derek Leroith, Mount Sinai School of Medicine, USA
IGFs, Obesity, Diabetes and Cancer

Tuesday, January 24 | 5:00PM - 7:00PM
Adipose Tissue, Lipids and Diabetes
Room: Columbia Ballroom

Speaker 3 of 4
Jeffrey Flier, Harvard University, USA
Novel Pathways for Regulating Body Weight and Insulin Resistance

Tuesday, January 24 | 5:00PM - 7:00PM
Adipose Tissue, Lipids and Diabetes
Room: Columbia Ballroom

Speaker 4 of 4
Paul F. Pilch, Boston University School of Medicine, USA
Caveolin-1/Cholesterol Modulates Transmembrane Fatty Acid Movement

Tuesday, January 24 | 5:00PM - 7:00PM
Molecular Control of Insulin Sensitivity
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 1 of 6
* † Morris F. White, Boston Children's Hospital, Harvard Medical School, USA


Tuesday, January 24 | 5:00PM - 7:00PM
Molecular Control of Insulin Sensitivity
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 2 of 6
Michael P. Czech, University of Massachusetts Medical School, USA
Pathways Controlling Insulin Sensitivity in Adipose Cells


Tuesday, January 24 | 5:00PM - 7:00PM
Molecular Control of Insulin Sensitivity
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 3 of 6
Evan D. Rosen, Harvard University, USA
A Genomic Screen for the Cellular Basis of Insulin Resistance


Tuesday, January 24 | 5:00PM - 7:00PM
Molecular Control of Insulin Sensitivity
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 4 of 6
Timothy E. McGraw, Weill Medical College of Cornell University, USA
Molecular Control of Glucose Uptake


Tuesday, January 24 | 5:00PM - 7:00PM
Molecular Control of Insulin Sensitivity
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 5 of 6
Liza Makowski, University of North Carolina at Chapel Hill, USA
Short Talk: A Novel Role for Mitochondrial-derived Fatty Acid Metabolites in Regulating Insulin Signaling


Tuesday, January 24 | 5:00PM - 7:00PM
Molecular Control of Insulin Sensitivity
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 6 of 6
Sarah L. Dunn, Children's Hospital Boston, USA
Short Talk: Serine Phosphorylation of Irs2: Regulation of Irs2(Ser965) Phosphorylation by MAP kinase Pathways


Tuesday, January 24 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Tuesday, January 24 | 7:30PM - 10:00PM
Poster Session 3
Room: Pacific Ballroom


Wednesday, January 25 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Wednesday, January 25 | 8:00AM - 11:15AM
Complications
Room: Columbia Ballroom

Speaker 1 of 6
* Michael A. Brownlee, Albert Einstein College of Medicine, USA

Wednesday, January 25 | 8:00AM - 11:15AM
Complications
Room: Columbia Ballroom

Speaker 2 of 6
John S. Yudkin, University of College London, UK
Adipocytokines, Insulin Resistance and Vascular Disease - Common Pathways?

Wednesday, January 25 | 8:00AM - 11:15AM
Complications
Room: Columbia Ballroom

Speaker 3 of 6
Ann Marie Schmidt, New York University Langone Medical Center, USA
RAGE, Inflammation and the Complications of Diabetes



Wednesday, January 25 | 8:00AM - 11:15AM
Complications
Room: Columbia Ballroom

Speaker 4 of 6
Mason W. Freeman, Massachusetts General Hospital, USA
Type II Diabetes and Atherosclerosis

Wednesday, January 25 | 8:00AM - 11:15AM
Complications
Room: Columbia Ballroom

Speaker 5 of 6
Juleen R. Zierath, Karolinska Institutet, Sweden
Insulin and AMPK Signaling in Skeletal Muscle: Validation of Targets to Prevent and Treat Type 2 Diabetes Mellitus

Wednesday, January 25 | 8:00AM - 11:15AM
Complications
Room: Columbia Ballroom

Speaker 6 of 6
Yaacov Barak, Magee-Womens Research Institute, USA
Short Talk: PPARgamma, Adipose Tissue Inflammation and the Metabolic Syndrome

Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 1 of 7
* Fumihiko Urano, Washington University School of Medicine, USA


Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 2 of 7
Jonathan S. Weissman, Whitehead Institute and MIT, USA
Exploration of the Topological Requirements of ERAD Identifies Yos9p as a Lectin Sensor of Misfolded Glycoproteins in the ER Lumen


Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 3 of 7
Takashi Kadowaki, University of Tokyo, Japan
Adiponenctin,Adiponenctin Receptors, and Metabolic Regulation


Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 4 of 7
Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA
Part I: Resistin and Atherosclerosis
Part II: A Post-Translational Nuclear Receptor Switch That Synchronizes Circadian Rhythms


Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 5 of 7
Jeffrey E. Pessin, Albert Einstein College of Medicine, USA
Regulation of Insulin Responsive Vesicle Trafficking in Adipocytes


Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 6 of 7
Hans P.M.M. Lauritzen, Denmark
Short Talk: Imaging of Insulin Signaling in Skeletal Muscle of Living Mice Shows Major Role of T-Tubules


Wednesday, January 25 | 8:00AM - 11:15AM
Secretory Pathway and Energy Homeostasis
This session is from Diabetes Mellitus
Room: British Ballroom

Speaker 7 of 7
Sonya G. Fonseca, Novartis, USA
Short Talk: WFS1 is Important in Mitigating Endplasmic Retuculum Stress in Beta Cells through the Unfolded Protein Response


Wednesday, January 25 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Wednesday, January 25 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Wednesday, January 25 | 5:00PM - 7:00PM
Metabolic Crosstalk and Energy Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 1 of 6
* Silvia Corvera, University of Massachusetts Medical School, USA

Wednesday, January 25 | 5:00PM - 7:00PM
Metabolic Crosstalk and Energy Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 2 of 6
* Philipp E. Scherer, University of Texas Southwestern Medical Center, USA

Wednesday, January 25 | 5:00PM - 7:00PM
Metabolic Crosstalk and Energy Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 3 of 6
C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Tissue Specific PPARgamma Effects, Insulin Responsiveness and Energy Homeostasis

Wednesday, January 25 | 5:00PM - 7:00PM
Metabolic Crosstalk and Energy Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 4 of 6
Stephen O'Rahilly, University of Cambridge, UK
Human Obesity and Insulin Resistance: Lessons from Experiments of Nature

Wednesday, January 25 | 5:00PM - 7:00PM
Metabolic Crosstalk and Energy Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 5 of 6
Gerald I. Shulman, Yale University School of Medicine, USA
Mitochondrial Dysfunction and Type 2 Diabetes

Wednesday, January 25 | 5:00PM - 7:00PM
Metabolic Crosstalk and Energy Homeostasis (Joint)
Room: British Columbia Ballroom

Speaker 6 of 6
Silvana Obici, University of Cincinnati, USA
Short Talk: Metabolic Consequences of the Activation of the Hexosamine Biosynthesis Pathway in Skeletal Muscle

Wednesday, January 25 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Wednesday, January 25 | 8:00PM - 11:00PM
Entertainment
Room: Pacific Ballroom


Wednesday, January 25 | 8:00PM - 11:00PM
Cash Bar
Room: Pacific Ballroom


Thursday, January 26 | 10:26AM - 10:26AM
Departure


*Session Chair.