Web Desc
HIV Vaccines
joint with HIV Pathogenesis
Organizer(s): Ruth M. Ruprecht, Genoveffa Franchini and Susan W. Barnett
Date: March 27 - April 02, 2006
Location: Keystone Resort, Keystone, CO, USA
Part of the Global Health Series, Supported by the Bill & Melinda Gates Foundation
Summary of Meeting:
The Vaccine Symposium will focus on basic aspects of antigen presentation, with a special attention to the role of MHC class II and the generation of antibodies. Over the last few years, MHC class I-restricted cytotoxicity lymphocytes (CTL) have been in the limelight. However, vaccine strategies aimed at generating CTL responses have only been partially protective and have not provided protection from infection. In contract, passive immunization studies by various groups have clearly shown that neutralizing antibodies can provide complete protection from infection. A challenge to scientists in the AIDS vaccine development field is now to find ways of generating neutralizing antibodies with the desired epitope specificities at sufficiently high levels through active vaccination using novel immunogens. Last but not least, the topic of innate immunity and its role in leading to adaptive immune responses will also be highlighted.
Scholarship Deadline: November 29 2005
Discounted Abstract Deadline: November 29 2005
Abstract Deadline: December 20 2005
Discounted Registration Deadline: January 27 2006
We gratefully acknowledge additional support for this conference from:
Bill & Melinda Gates Foundation
GenVec, Inc.
Gilead Sciences, Inc.Office of AIDS Research, NIH
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Chiron Corporation

Merck & Co., Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13 AI068371-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Monday, March 27 | 3:00PM - 7:30PM
Registration
Room: Longs Peak Foyer


Monday, March 27 | 6:30PM - 7:30PM
Refreshments
Room: Longs Peak Foyer


Monday, March 27 | 7:30PM - 9:30PM
Keynote Address (Joint)
Room: Longs/Grays Peak

Speaker 1 of 4
* Tristram G. Parslow, Emory University, USA
Introduction of HIV Pathogenesis Meeting

Monday, March 27 | 7:30PM - 9:30PM
Keynote Address (Joint)
Room: Longs/Grays Peak

Speaker 2 of 4
Joseph G. Sodroski, Dana-Farber Cancer Institute, USA
Antiretroviral Activity of TRIM5 and Related TRIM Proteins

Monday, March 27 | 7:30PM - 9:30PM
Keynote Address (Joint)
Room: Longs/Grays Peak

Speaker 3 of 4
* Ruth M. Ruprecht, Texas Biomedical Research Institute, USA
Introduction of HIV Vaccines Meeting

Monday, March 27 | 7:30PM - 9:30PM
Keynote Address (Joint)
Room: Longs/Grays Peak

Speaker 4 of 4
Ulrich H. Von Andrian, Harvard Medical School, USA
Homing And Cellular Traffic In Lymphoid Tissues

Tuesday, March 28 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys/Red Cloud


Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 1 of 8
* Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 2 of 8
* Ulrich H. Von Andrian, Harvard Medical School, USA

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 3 of 8
Joana Loureieo, Whitehead Institute for Biomedical Research, USA
Antigen Presentation via MHC Class II

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 4 of 8
Robert A. Seder, NIAID, National Institutes of Health, USA
Toll-like Receptor Ligands Influence the Magnitude and Quality of HIV Specific Immune Responses in Non-human Primates

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 5 of 8
Mary A. Marovich, NIAID, National Institutes of Health, USA
DC Vaccinations with HIV Antigens in Humans

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 6 of 8
Donald I. Van Ryk, NIAID, National Institutes of Health, USA
Short Talk: DC-SIGN Capture of HIV gp120 Relies on Avidity Effects, and is Altered by CD4 Ligation

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 7 of 8
Paolo Monini, Istituto Superiore di Sanità, Italy
Short Talk: Native Tat Enters Preferentially Dendritic Cells Inducing Tumor Necrosis Factor-alpha-Mediated Th1-Polarized Maturation and Immune Responses in Monkeys

Tuesday, March 28 | 8:00AM - 11:00AM
Antigen Presentation and Dendritic Cells
Room: Longs Peak

Speaker 8 of 8
Christine Trumpfheller, Roche Glycart, Switzerland
Short Talk: Intensified and Protective CD4+ T Cell Immunity with Anti-Dendritic Cell HIV GAG Fusion Antibody Vaccine

Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 7
* Tristram G. Parslow, Emory University, USA


Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 7
Michael F. Summers, HHMI/University of Maryland, Baltimore County, USA
Structural Basis for Specific Membrane Targeting by the HIV-1 Gag Protein


Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 7
Hans-Georg Kräusslich, Universitat Heidelberg, Germany
HIV Assembly and its Inhibition


Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 7
Peter E. Prevelige, University of Alabama, Birmingham, USA
HIV Core Assembly and Its Inhibitors


Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 7
Wei-Shau Hu, National Cancer Institute, National Institutes of Health, USA
Recombination and Complementation: Two Modes of Interactions among HIVs


Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 6 of 7
Jacob Anglister, Weizmann Institute of Science, Israel
Short Talk: Cross-Strand Electrostatic Interactions at the Base of the â-Hairpin of the HIV-1 V3 Region Create a Molecular Switch for Phenotype Conversion


Tuesday, March 28 | 8:00AM - 11:15AM
Lessons from the Virus
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 7 of 7
Nathalie Arhel, Institut Pasteur, France
Short Talk: Video Imaging of HIV-1 Intracellular Transport and Role of the Central DNA Flap in Active Nuclear Import


Tuesday, March 28 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 28 | 11:00AM - 1:00PM
Poster Setup
Room: Shavano/Torreys/Red Cloud


Tuesday, March 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys/Red Cloud


Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 1 of 7
* Gene M. Shearer, National Cancer Institute, National Institutes of Health, USA

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 2 of 7
Susanna C. Trapp, University of Cologne, Germany
Co-Pathogens and HIV TLR3 Stimulation Dampens HIV Replication

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 3 of 7
Sophie Chabot, USA
Mucosal Application of TLR2 Ligands Modulates the Gatekeeping Functions of the Follicle-Associated Epithelium to Promote Vaccine Uptake at Mucosal Surfaces

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 4 of 7
Daniel G. Kavanagh, USA
Transfection of Antigen-Loaded Dendritic Cells With mRNA Encoding IL-12 p70 Leads to Increased Expansion of HIV-Specific T Cells and Activation of Natural Killer Cells in vitro

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 5 of 7
Thomas Lehner, Guy's, King's & St. Thomas' Hospital Medical and Dental School, UK
Stimulation of Intracellular and Extracellular Innate Immune Responses to SIV and HIV-1

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 6 of 7
* Jay A. Berzofsky, NCI, National Institutes of Health, USA
Circumventing CD4 Deficiency to Induce Long-Lived Memory CTL

Tuesday, March 28 | 2:30PM - 4:30PM
Workshop 1: Boundary between Innate and Adaptive Immunity
Room: Longs Peak

Speaker 7 of 7
Marjorie Robert-Guroff, NCI, National Institutes of Health, USA
Cellular Immunity following Systemic SIV DNA Priming/Mucosal Replication-Competent Ad-SIV Boosting of Rhesus Macaques is Enhanced by Cytokine DNAs and Includes Potent Mucosal CD8+T Cell Memory Responses

Tuesday, March 28 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 1 of 7
* Robert A. Seder, NIAID, National Institutes of Health, USA

Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 2 of 7
* Susan W. Barnett, Bill & Melinda Gates Foundation, USA

Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 3 of 7
Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA
Plasmacytoid DC: Linking Innate and Adaptive Immunity

Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 4 of 7
Jay A. Levy, University of California, San Francisco, USA
Importance of Innate Immunity in HIV Infection and Vaccine Development

Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 5 of 7
Galit Alter, MIT and Harvard University, USA
Short Talk: NK Cells Respond Directly to HIV Derived Single-Stranded RNA via TLR in an APC Dependent Manner

Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 6 of 7
Nada M. Melhem, University of Pittsburgh, USA
Short Talk: Dendritic Cells Expressing Autologous Viral RNA Stimulate T-Cell Responses that Accurately Reflecting Virus Evolution during SIV Infection



Tuesday, March 28 | 5:00PM - 7:00PM
Harnessing Innate Immunity for Vaccines
Room: Longs Peak

Speaker 7 of 7
Wei Jiang, Case Western Reserve University, USA
Short Talk: TLR9 Ligation Induces Naïve B Cell Proliferation Independent of B Cell Receptor Activation

Tuesday, March 28 | 5:00PM - 7:00PM
Lessons from the Target Cell (I) -- Factors that Inhibit
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 5
* Warner Craig Greene, Gladstone Institute of Virology and Immunology, USA
New Perspectives on APOBEC3G Anti-retroviral Action and Regulation


Tuesday, March 28 | 5:00PM - 7:00PM
Lessons from the Target Cell (I) -- Factors that Inhibit
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 5
Kevin C. Klein, University of Washington, USA
Short Talk: Apobec3G Adopts Different Conformations in the Presence and Absence of RNA that may Correlate with Enzymatic Activity


Tuesday, March 28 | 5:00PM - 7:00PM
Lessons from the Target Cell (I) -- Factors that Inhibit
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 5
Philippe Gallay, The Scripps Research Institute, USA
Short Talk: Selective Destruction of the HIV-1 Capsid Shell by TRIM5alpha


Tuesday, March 28 | 5:00PM - 7:00PM
Lessons from the Target Cell (I) -- Factors that Inhibit
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 5
Klaus Strebel, NIAID, National Institutes of Health, USA
Short Talk: Degradation of APOBEC3G and Rescue of Viral Infectivity are Separable Activities of HIV-1 Vif


Tuesday, March 28 | 5:00PM - 7:00PM
Lessons from the Target Cell (I) -- Factors that Inhibit
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 5
Kyeongeun Lee, NCI, National Institutes of Health, USA
Short Talk: HIV-1 Cell Killing Blocked by Pre-mRNA Factor CPSF6


Tuesday, March 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys/Red Cloud


Tuesday, March 28 | 7:30PM - 10:00PM
Poster Session 1
Room: Shavano/Torreys/Red Cloud


Wednesday, March 29 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys/Red Cloud


Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 1 of 9
* Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 2 of 9
* John R. Mascola, NIAID, National Institutes of Health, USA

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 3 of 9
Shane Crotty, La Jolla Institute for Immunology, USA
Long Term Antibody Responses and B Cell Memory in Humans after Vaccination

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 4 of 9
Richard T. Wyatt, IAVI Neutralizing Antibody Center, The Scripps Research Institute, USA
HIV-1 Envelope Glycoprotein Structural Analysis for Improved Immunogen Design

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 5 of 9
Ping Zhu, Florida State University, USA
Short Talk: Distribution and Three-Dimensional Structure of AIDS Virus Envelope Spikes

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 6 of 9
Herman F. Staats, Duke University Medical Center, USA
Secretory IgA and HIV-1 Vaccines

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 7 of 9
Ruth M. Ruprecht, Texas Biomedical Research Institute, USA
Vaccine Development Against HIV clade C in a Primate Model Involving SHIV clade C Mucosal Challenges

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 8 of 9
Frederic Bibollet-Ruche, University of Pennsylvania, USA
Short Talk: Detection of Novel Neutralizing Antibody Responses to the Membrane Proximal External Region (MPER) of GP41 following Infection by HIV-1 Subtypes A, B, C, D, F, G, H, CRF01, CRF02, OR CRF11

Wednesday, March 29 | 8:00AM - 11:30AM
B-Cell Development and Antibody Generation
Room: Grays/Longs Peak

Speaker 9 of 9
Amandeep K. Gakhal, Sutro Biopharma, USA
Short Talk: Dissecting the Neutralizing Antibody Specificities of Broadly Neutralizing Sera from HIV-1 Infected Donors

Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 7
* Carol A. Carter, State University of New York - Stony Brook, USA
Tsg101 and Other Cofactors of HIV Release


Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 7
John A. T. Young, F.Hoffmann-La Roche Ltd, Switzerland
Cellular Cofactors in Early Steps of Retroviral Entry


Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 7
Angela Ciuffi, Institute of Microbiology - CHUV/UNIL, Switzerland
Short Talk: HIV Integration Site Selection is Directed by Cellular LEDGF/p75


Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 7
Vicente Planelles, University of Utah, USA
Short Talk: Vpr Induces Bax-Dependent Apoptosis Downstream of G2 Checkpoint Activation


Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 7
Serge Benichou, Cochin Institute, France
Short Talk: Dynamic Interaction of HIV-1 Nef with Clathrin at the Plasma Membrane Revealed by Evanescent Wave Fluorescence Microscopy


Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 6 of 7
René Daniel, Thomas Jefferson University, USA
Short Talk: Nijmegen Breakage Syndrome Protein 1 Controls the ATM-Dependent DNA Damage Response to HIV-1 Integration


Wednesday, March 29 | 8:00AM - 11:00AM
Lessons from the Target Cell (II) -- Factors that Enhance
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 7 of 7
Erik S. Zimmerman, University of Utah, USA
Short Talk: Mechanism of Induction of G2 Arrest by HIV-1 Vpr in vivo


Wednesday, March 29 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, March 29 | 11:30AM - 1:00PM
Poster Setup
Room: Shavano/Torreys/Red Cloud


Wednesday, March 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys/Red Cloud


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 8
* Vinay K. Pathak, National Cancer Institute, National Institutes of Health, USA
Identification of APOBEC3G Mutants that Exhibit a Defect in Virion Incorporation


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 8
Krishan K. Pandey, St. Louis University Health Sciences Center, USA
Human LEDGF/p75 Modulates Assembly and Disassembly of HIV-1 Synaptic Complexes in vitro


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 8
Rik Gijsbers, Katholieke Universiteit Leuven, Belgium
Overexpression of the LEDGF/p75 Integrase Binding Domain abrogates HIV-1 Replication


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 8
Steven P. Edgcomb, The Scripps Research Institute, USA
Attenuation of Rev Function by Modulation of the Oligomerization Domain


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 8
Richard E. Sutton, Yale University School of Medicine, USA
Human Chromosome 2 Carries a Gene that Allows Infectious HIV Release from Mouse Cells


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 6 of 8
Katrina Nolan, University of Pennsylvania, USA
HIV-1 Variants Containing Partial Deletions within the V3 Loop: Effects on X4 vs. R5 Tropism and Sensitivity to Entry Inhibitors


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 7 of 8
Elena Gustchina, NIDDK, National Institutes of Health, USA
Fusion Inhibitors Targeting N- and C-Heptad Repeat Regions of Pre-hairpin Intermediate of gp41 Inhibit Fusion Synergistically


Wednesday, March 29 | 2:30PM - 4:30PM
Workshop 1: Therapeutic Targets in the Virus and Host
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 8 of 8
John J. Dwyer, Trimeris Inc., USA
Design and Mechanism of Action of Fusion Inhibitor Peptides with Enhanced Activity Against ENF-Resistant Virus


Wednesday, March 29 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 1 of 7
* Ruth M. Ruprecht, Texas Biomedical Research Institute, USA

Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 2 of 7
* Nelson L. Michael, Walter Reed Army Institute of Research, USA

Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 3 of 7
Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA
Defining Shared Epitopes that Induce Broadly Neutralizing Antibodies

Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 4 of 7
Gary J. Nabel, Sanofi, USA
New Antigen Designs for Env Responses

Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 5 of 7
Barton F. Haynes, Duke University Medical Center, USA
Immunoregulation of Broadly Reactive Anti-HIV Antibody Responses

Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 6 of 7
Morgane Bomsel, Institut Cochin, France
Short Talk: Characterization of HIV-1 Neutralizing Anti gp41-IgA by Screening a Phage-Display Fab IgA Library Derived from Mucosal Cells from HIV Highly Exposed but IgG sero Negative Individuals

Wednesday, March 29 | 5:00PM - 7:15PM
Lessons from the Immune Response I (Joint)
Room: Longs Peak

Speaker 7 of 7
George M. Shaw, University of Pennsylvania, USA
Short Talk: Characterization of HIV-1 Envelope in Acute HIV-1 Infection

Wednesday, March 29 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys/Red Cloud


Wednesday, March 29 | 7:30PM - 10:00PM
Poster Session 2
Room: Shavano/Torreys/Red Cloud


Thursday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys/Red Cloud


Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 1 of 8
* Jay A. Levy, University of California, San Francisco, USA

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 2 of 8
* Judy Lieberman, Harvard University, USA
Mechanisms of CTL Killing

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 3 of 8
Rafick Sekaly, Emory University, USA
Memory T Cell Homeostasis in the Natural History of HIV Infection

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 4 of 8
Sarah L. Rowland-Jones, Oxford University, UK
Long-Term Non-Progression with HIV Infection: Lessons from HIV-2

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 5 of 8
Mark B. Feinberg, IAVI International AIDS Vaccine Initiative, USA
Host-Virus Relationships in Nonpathogenic SIV Infections

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 6 of 8
David Price, Cardiff University School of Medicine, UK
Short Talk: Functional Consequences of Peptide-Major Histocompatibility Complex Class I Antigen Presentation in the Context of Enhanced CD8 Coreceptor Binding: Implications for Vaccine Delivery

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 7 of 8
Arne Schneidewind, Massachusetts General Hospital, USA
Short Talk: Impact of HLA-B27-Associated CTL Escape Mutations on HIV-1 Replicative Fitness

Thursday, March 30 | 8:00AM - 11:30AM
Lessons from the Immune Response II (Joint)
Room: Longs Peak

Speaker 8 of 8
Photini Kiepiela, University of KwaZulu Natal, South Africa
Short Talk: Epitope-Specific Differences in Control of HIV-1 Infection

Thursday, March 30 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, March 30 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys/Red Cloud


Thursday, March 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys/Red Cloud


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 7
* Anna Aldovini, Boston Children's Hospital and Harvard Medical School, USA
TRAIL-Mediated Apoptosis is Induced by HIV and SIV in Human and Macaque CD4+ T Cells but does Not Occur in Virus-Exposed CD4+ T cells from AIDS-Resistant Species


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 7
Elena Martinelli, Population Council, USA
HIV-1 gp120 Inhibits TLR9 Mediated Activation and IFN-gamma Secretion in Plasmacytoid Dendritic Cells


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 7
Ivona Pandrea, University of Pittsburgh, USA
Dramatic CD4+ T Cell Depletion in the Intestine is a Hallmark of SIVagm.sab Infection in Caribbean AGMs


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 7
David E. Verhoeven, Iowa State University, USA
Mechanistic and Phenotypic Analysis of Delayed Restoration of Intestinal CD4+ Lymphocytes during Antiviral Therapy of SIV Infected Rhesus Macaques


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 7
Desiree Kunkel, BCRT, Germany
Regulatory T Cells in the Gastrointestinal Mucosa in HIV/SIV Infection


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 6 of 7
Bin Li, USA
Rapid Reversion of Transmitted Sequence Polymorphisms Dominates Early HIV-1 Evolution


Thursday, March 30 | 2:30PM - 4:30PM
Workshop 2: HIV Pathogenesis in Host Cells and Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 7 of 7
James P. Gregson, Brigham Young University, USA
Distinct HIV Compartmentalization In and Among Secondary Lymphoid Tissues


Thursday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 1 of 8
* Richard A. Koup, NIAID, National Institutes of Health, USA

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 2 of 8
* Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 3 of 8
Susan L. Swain, University of Massachusetts Medical School, USA
Mechanisms of Influenza Protection by Primed CD4 T Cells

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 4 of 8
David A. Hafler, Yale University School of Medicine, USA
Human T Regulatory Cells

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 5 of 8
Chungwon Chung, VMRD, USA
Short Talk: Clonal Variation of CD8+ T Lymphocyte Efficacy in Suppression of SIV Replication

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 6 of 8
Adriano Boasso, Imperial College London, UK
Short Talk: Increased Regulatory T Cell Markers and Indoleamine 2,3 Dioxygenase in Spleen and Gut of SIV-Infected Macaques

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 7 of 8
Elizabeth Ramona Sharp, University of California, San Francisco, USA
Short Talk: The Influence of CD4+CD25+ Regulatory T Cells on HLA-A2 Restricted HIV-Specific Immune Responses during Early and Chronic Infection

Thursday, March 30 | 5:00PM - 7:15PM
T Cells: Effectors versus Suppressors
Room: Longs Peak

Speaker 8 of 8
Jakob Nilsson, Karolinska Institute, Sweden
Short Talk: A Direct Correlation between FOXP3 Expressing Regulatory T- Cells Present in Lymphoid Tissue and Viral Load of Untreated Chronically HIV-1 Infected Individuals

Thursday, March 30 | 5:00PM - 7:15PM
Lessons from Other Viruses
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 5
* Stephen P. Goff, Columbia University, USA
Host Restriction of Retrovirus Replication


Thursday, March 30 | 5:00PM - 7:15PM
Lessons from Other Viruses
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 5
Jonathan P. Stoye, Francis Crick Institute, UK
A Collection Of Retrovirus Restriction Factors


Thursday, March 30 | 5:00PM - 7:15PM
Lessons from Other Viruses
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 5
Hung Y. Fan, University of California, Irvine, USA
Oncogenic Properties of the Envelope Protein of Jaagsiekte Sheep Retrovirus


Thursday, March 30 | 5:00PM - 7:15PM
Lessons from Other Viruses
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 5
James H. McLinden, University Of Iowa, USA
Short Talk: Hepatitis C Virus and GB Viruses B and C NS5A Proteins Inhibit HIV Replication in Jurkat Cells


Thursday, March 30 | 5:00PM - 7:15PM
Lessons from Other Viruses
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 5
Melody G. Duvall, NIAID, National Institutes of Health, USA
Short Talk: Maintenance of HIV-Specific CD4+ T Cell Help Distinguishes HIV-2 from HIV-1 Infection


Thursday, March 30 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys/Red Cloud


Thursday, March 30 | 7:30PM - 10:00PM
Poster Session 3
Room: Shavano/Torreys/Red Cloud


Friday, March 31 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys/Red Cloud


Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 1 of 9
* Satya Dandekar, University of California, Davis, USA

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 2 of 9
* Herman F. Staats, Duke University Medical Center, USA

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 3 of 9
Barbara L. Shacklett, University of California, Davis, USA
HIV-1 Specific T-Cell Responses in Mucosal Tissues

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 4 of 9
Susan W. Barnett, Bill & Melinda Gates Foundation, USA
Trimeric HIV Env: Improved Adjuvants and Delivery

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 5 of 9
Leonidas Stamatatos, Fred Hutchinson Cancer Research Center, USA
Distinct Immunogenic Properties of the SF162 Env on Infectious Virions and Soluble gp140 Protein

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 6 of 9
Julia L. Hurwitz, St. Jude Children's Research Hospital, USA
Pre-Clinical and Clinical Development of a Multi-Envelope HIV-1 Vaccine

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 7 of 9
Thorsten Demberg, NCI, National Institutes of Health, USA
Short Talk: Immunogenicity and Protective Efficacy of Prime/Boost Vaccine Regimens based on Replication-Competent Ad Recombinants Encoding HIVtat, HIVenv, SIVgag, and SIVnef in a Rhesus Macaque SHIV89.6P Challenge Model

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 8 of 9
Andreas Mörner, Public Health Agency of Sweden, Sweden
Short Talk: CD4 and CD8 IFN-gamma and IL-2 Responses and Control of SHIV Replication in Macaques Immunized with Multi-Gene Cocktail DNA or SFV followed by MVA

Friday, March 31 | 8:00AM - 11:30AM
Mucosal Immunity / Preclinical Studies
Room: Longs Peak

Speaker 9 of 9
Siew Yen Chong, Wyeth Pharmaceuticals, USA
Short Talk: Immunogenicity of Attenuated Recombinant Vesicular Stomatitis Virus Vectors Expressing HIV GAG in Rhesus Macaques

Friday, March 31 | 8:00AM - 11:15AM
Lessons from Therapy
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 6
* John M. Coffin, Tufts University, USA
Host-Virus Interactions


Friday, March 31 | 8:00AM - 11:15AM
Lessons from Therapy
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 6
François Clavel, IUH, Université Paris Diderot, France
HIV Drug Resistance : Viral Strategies for Treatment Escape


Friday, March 31 | 8:00AM - 11:15AM
Lessons from Therapy
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 6
Roland Marquet, IBMC du Centre National de la Recherche Scientifique, France
Short Talk: Targeting the Dimerization Initiation Site of HIV-1 Genomic RNA with Aminoglycosides: From Crystal to Cell


Friday, March 31 | 8:00AM - 11:15AM
Lessons from Therapy
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 6
Andreas Schweizer, University Hospital Zurich, Switzerland
Short Talk: CD4-Specific Designed Ankyrin Repeat Proteins Potently Inhibit HIV Entry


Friday, March 31 | 8:00AM - 11:15AM
Lessons from Therapy
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 6
Monica Macal, Five Prime Therapeutics, Inc, USA
Short Talk: Restoration of the Gut Mucosal Immune System in HIV Infected Patients during HAART


Friday, March 31 | 8:00AM - 11:15AM
Lessons from Therapy
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 6 of 6
Ruy M. Ribeiro, University of Lisbon, Portugal
Short Talk: Naïve and Memory Cell Turnover as Drivers of CCR5 to
CXCR4-Tropism Switch in HIV-1: Implications for Therapy


Friday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Friday, March 31 | 11:30AM - 1:00PM
Poster Setup
Room: Shavano/Torreys/Red Cloud


Friday, March 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys/Red Cloud


Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 1 of 8
* Richard T. Wyatt, IAVI Neutralizing Antibody Center, The Scripps Research Institute, USA

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 2 of 8
Miroslaw K. Gorny, New York University School of Medicine, USA
A Neutralizing Epitope is Present on Env Trimers but not Monomers Expressed on the Virions Pseudotyped with Env SF162

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 3 of 8
* Harriet L. Robinson, GeoVax Inc., USA
Correlation of the Avidity of anti-Env Ab with Neutralizing Activity for Incident Isolates

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 4 of 8
Yuxing Li, University of Maryland, USA
Analysis of the Neutralizing Specificity in Complex Polyclonal Sera

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 5 of 8
Rogier W. Sanders, University of Amsterdam and Weill Cornell Medical College, Netherlands
Functional Improvement of V1/V2-Deleted HIV-1 gp120 through Forced Virus Evolution

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 6 of 8
Hui Li, University of Pennsylvania, USA
Conservation of the Neutralization Epitope for 4E10, but not 2F5, in Human and Simian Immunodeficiency Viruses of Diverse Evolutionary Origins

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 7 of 8
Madhumita Mahalanabis, University of Washington, USA
Key Mutations in SIV Envelope of Macaques with Heterologous Neutralizing Antibody Responses

Friday, March 31 | 2:30PM - 4:30PM
Workshop 2: Neutralizing Antibodies
Room: Longs Peak

Speaker 8 of 8
Dan H. Barouch, Beth Israel Deaconess Medical Center, USA
Hexon-Chimeric Adenovirus Serotype 5 Vectors Effectively Circumvent Pre-Existing Anti-Vector Immunity

Friday, March 31 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 1 of 7
* Louis J. Picker, Oregon Health & Science University, USA

Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 2 of 7
Marta L. Marthas, California National Primate Research Center, USA
Role for Innate Immunity in Protection of Vaccinated Infant Macaques Against Oral SIV: Has Terminology Limited How We Evaluate Vaccine Immunogenicity and Efficacy?

Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 3 of 7
* Neil Almond, National Institute Biology Standards, UK
The Characterisation of Protection Conferred by Live Attenuated SIV

Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 4 of 7
Francisco Veas, Institut de Recherche pour le Development, France
Short Talk: New Innate Immune Correlates in Caucasian HIV Exposed Uninfected Individuals

Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 5 of 7
Genoveffa Franchini, NCI, National Institutes of Health, USA
Importance of CD4+ T Cells in the Maintenance of SIV-Specific CD8+ T Memory Cells and their Role in Protection from SIVmac251

Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 6 of 7
Melissa Precopio, Ragon Institute of MGH, MIT, and Harvard, USA
Short Talk: Immunization with Vaccinia Virus Induces Polyfunctional T Cell Responses

Friday, March 31 | 5:00PM - 7:30PM
Correlates of Protection Against Infection or Disease
Room: Grays/Longs Peak

Speaker 7 of 7
Scott A. Brown, St. Jude Children's Research Hospital, USA
Short Talk: HIV-1-Envelope-Specific CD4+ T-Cells Control Virus Challenge without CD8+ T-Cell or B-Cell Contributions in a Mouse Model System

Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 7
* James E.K. Hildreth, UC Davis College of Biological Sciences, USA


Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 7
Robert F. Siliciano, Johns Hopkins University School of Medicine, USA
HIV Resevoirs, Latency, and Evolution


Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 7
Thijs van Montfort, Academic Medical Center, Netherlands
Short Talk: Transfer of Antibody Neutralized HIV-1 from Dendritic Cells
and DC-SIGN Expressing Cells to CD4 Lymphocytes


Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 7
Jason M. Brenchley, NIAID, National Institutes of Health, USA
Short Talk: Continued Infection of Mucosal CD4+ T Cells is Associated with Mucosal Depletion Despite Years of Antiretroviral Therapy


Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 7
Paul J. Peters, University of Massachusetts, USA
Short Talk: Macrophage-Tropic R5 Envelopes are Infrequent in Blood,
Lymph Nodes and Semen: Implications for Transmission and Pathogenesis


Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 6 of 7
Jacob D. Estes, Oregon Health and Science University, USA
Short Talk: Rapid Secondary Lymphatic Tissue Fibrosis in Pathogenic SIV-Infected Rhesus Macaques Mediated by TGFbeta1+ Tregs


Friday, March 31 | 5:00PM - 7:00PM
Lessons from the Tissues
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 7 of 7
Jean-Charles J. B. Grivel, Sidra Medical and Research Center, Qatar
Short Talk: HIV-1 Replication in Rectal Mucosa and Tonsillar Explant


Friday, March 31 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys/Red Cloud


Friday, March 31 | 7:30PM - 10:00PM
Poster Session 4
Room: Shavano/Torreys/Red Cloud


Saturday, April 01 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys/Red Cloud


Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 1 of 7
* Gary J. Nabel, Sanofi, USA

Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 2 of 7
* Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA

Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 3 of 7
Barney S. Graham, NIAID, National Institutes of Health, USA
Update on VRC Clinical Trials

Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 4 of 7
John A. Hural, HIV Vaccine Trials Network, USA
Short Talk

Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 5 of 7
Barbara Ensoli, Istituto Superiore di Sanita, Italy
Tat-Based Vaccines: From Basic Science to Clinical Trials

Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 6 of 7
Nelson L. Michael, Walter Reed Army Institute of Research, USA
U.S. Military HIV Research Program Preventive Vaccine Trials

Saturday, April 01 | 8:00AM - 11:00AM
Clinical Trials: Prophylactic Vaccines
Room: Longs Peak

Speaker 7 of 7
Shan Lu, University of Massachusetts Medical Center, USA
Short Talk: Update on the Immunogenicity and Safety of the Polyvalent DNA Prime-Protein Boost HIV-1 Vaccine Formulation DP6-001 in Healthy Volunteers

Saturday, April 01 | 8:00AM - 11:15AM
Lessons from Animal Models
This session is from HIV Pathogenesis
Room: Grays/Longs Peak

Speaker 1 of 6
Ronald C. Desrosiers, University of Miami Miller School of Medicine, USA
Replication-Competent and Replication-Incompetent SIV as Vaccines


Saturday, April 01 | 8:00AM - 11:15AM
Lessons from Animal Models
This session is from HIV Pathogenesis
Room: Grays/Longs Peak

Speaker 2 of 6
Jeffrey D. Lifson, Leidos Biomedical Research, Inc., USA
Inactivated Vaccines


Saturday, April 01 | 8:00AM - 11:15AM
Lessons from Animal Models
This session is from HIV Pathogenesis
Room: Grays/Longs Peak

Speaker 3 of 6
Louis J. Picker, Oregon Health & Science University, USA
New Insights in SIV Immunopathogenesis -- Connecting Viral Replication to Disease


Saturday, April 01 | 8:00AM - 11:15AM
Lessons from Animal Models
This session is from HIV Pathogenesis
Room: Grays/Longs Peak

Speaker 4 of 6
* Janice E. Clements, Johns Hopkins University, USA
Innate Immune Responses Regulate SIV Replication in Macrophages In Vivo


Saturday, April 01 | 8:00AM - 11:15AM
Lessons from Animal Models
This session is from HIV Pathogenesis
Room: Grays/Longs Peak

Speaker 5 of 6
Julie TerWee, Colorado State University, USA
Short Talk: Cellular Signaling following Receptor Engagement: Correlates with Pathogenicity


Saturday, April 01 | 8:00AM - 11:15AM
Lessons from Animal Models
This session is from HIV Pathogenesis
Room: Grays/Longs Peak

Speaker 6 of 6
Miles P. Davenport, University of New South Wales, Australia
Short Talk: Viral Load Predicts CD4+ T Cell Depletion in Acute SHIV Infection of Macaques


Saturday, April 01 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Saturday, April 01 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Saturday, April 01 | 5:00PM - 7:00PM
Immune Therapy in HIV and Cancer
Room: Longs Peak

Speaker 1 of 6
* Genoveffa Franchini, NCI, National Institutes of Health, USA

Saturday, April 01 | 5:00PM - 7:00PM
Immune Therapy in HIV and Cancer
Room: Longs Peak

Speaker 2 of 6
* Barney S. Graham, NIAID, National Institutes of Health, USA

Saturday, April 01 | 5:00PM - 7:00PM
Immune Therapy in HIV and Cancer
Room: Longs Peak

Speaker 3 of 6
Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA
Interstitial Dendritic Cells and Langerhans Cells Prime Humoral and Cellular Immunity Respectively

Saturday, April 01 | 5:00PM - 7:00PM
Immune Therapy in HIV and Cancer
Room: Longs Peak

Speaker 4 of 6
Montserrat Plana, Hospital Clinic, Spain
Short Talk: Functional and Phenotypic Characterization of HIV-Specific CD8 T Cells after Autologous Dendritic Cells Based Therapeutic Vaccine

Saturday, April 01 | 5:00PM - 7:00PM
Immune Therapy in HIV and Cancer
Room: Longs Peak

Speaker 5 of 6
Monica Vaccari, NCI, National Institutes of Health, USA
Short Talk: CTLA4 Blockade In Antiretroviral Therapy-Treated SIVmac251-Infected Macaques Does Not Augment Global T Cell Activation And Viral Replication

Saturday, April 01 | 5:00PM - 7:00PM
Immune Therapy in HIV and Cancer
Room: Longs Peak

Speaker 6 of 6
Johan K. Sandberg, Karolinska Institute, Sweden
Short Talk: Expansion of CD1d-Restricted NKT Cells in Patients with Primary HIV-1 Infection Treated with Interleukin-2

Saturday, April 01 | 5:00PM - 7:00PM
Lessons from the Real World
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 1 of 5
* Julie M. Overbaugh, Fred Hutchinson Cancer Research Center, USA


Saturday, April 01 | 5:00PM - 7:00PM
Lessons from the Real World
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 2 of 5
Grace John-Stewart, University of Washington, USA
Maternal-Infant HIV-1 Transmission


Saturday, April 01 | 5:00PM - 7:00PM
Lessons from the Real World
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 3 of 5
Eric Hunter, Emory University, USA
Early Events in HIV Infection: Lessons from Transmission Pairs


Saturday, April 01 | 5:00PM - 7:00PM
Lessons from the Real World
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 4 of 5
Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA
Elite Control of HIV Replication: Towards an Understanding of the Correlates of Immune Control


Saturday, April 01 | 5:00PM - 7:00PM
Lessons from the Real World
This session is from HIV Pathogenesis
Room: Grays Peak

Speaker 5 of 5
Anu Rebbapragada, University of Toronto, Canada
Short Talk: HSV2 and HIV Interaction: Negative Synergy in the Female Genital Tract


Saturday, April 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys/Red Cloud


Saturday, April 01 | 8:00PM - 11:00PM
Entertainment
Room: Shavano/Torreys/Red Cloud


Saturday, April 01 | 8:00PM - 11:00PM
Cash Bar
Room: Shavano/Torreys/Red Cloud


Sunday, April 02 | 10:26AM - 10:26AM
Departure


*Session Chair.