Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Drug Discovery for Parasitic Diseases (2016A5)
Drug Discovery for Protozoan Parasites (2012J1)
Drug Discovery for Protozoan Parasites (2009D2)

Web Desc
Drugs Against Protozoan Parasites Organizer(s): Daniel E. Goldberg, R. Kip Guy and Stephen A. Ward Date: January 28 - February 01, 2007 Location: Granlibakken Tahoe, Tahoe City, CA, USA Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation Summary of Meeting: This is a period of rapid progress for the field of anti-protozoal drug development. Genomic efforts have led to the identification of a myriad of new drug targets. Studies on the mechanisms of drug action and drug resistance have yielded new insights into how to improve on old agents. Promising development efforts span the spectrum from lead identification to clinical trials to registration. Key problems include target selection, drug development in an academia-centered environment, and performing trials in endemic areas. This meeting will bring together biologists and chemists with diverse backgrounds and scientists in academia and industry to work together towards solutions to these problems of global importance. Scholarship Deadline: September 28 2006 Discounted Abstract Deadline: September 28 2006 Abstract Deadline: October 27 2006 Discounted Registration Deadline: November 28 2006 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: GlaxoSmithKline We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1 R13 AI071682-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Drugs Against Protozoan Parasites

Organizer(s): Daniel E. Goldberg, R. Kip Guy and Stephen A. Ward

Date: January 28 - February 01, 2007
Location: Granlibakken Tahoe, Tahoe City, CA, USA

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation

Summary of Meeting:

This is a period of rapid progress for the field of anti-protozoal drug development. Genomic efforts have led to the identification of a myriad of new drug targets. Studies on the mechanisms of drug action and drug resistance have yielded new insights into how to improve on old agents. Promising development efforts span the spectrum from lead identification to clinical trials to registration. Key problems include target selection, drug development in an academia-centered environment, and performing trials in endemic areas. This meeting will bring together biologists and chemists with diverse backgrounds and scientists in academia and industry to work together towards solutions to these problems of global importance.

Scholarship Deadline: September 28 2006

Discounted Abstract Deadline: September 28 2006

Abstract Deadline: October 27 2006

Discounted Registration Deadline: November 28 2006

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

GlaxoSmithKline

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1 R13 AI071682-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, January 28 \| 3:00PM - 7:30PM Registration Room: Prefunction
Sunday, January 28 \| 7:30PM - 8:30PM Keynote Address Room: Mountain/Lake Rooms Speaker 1 of 1 Peter A. Winstanley, University of Liverpool, UK Tropical Drug Discovery - From Scientific Idea to Registered Product
Monday, January 29 \| 7:00AM - 8:00AM Breakfast Room: Granhall
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 1 of 7 * James H. McKerrow, University of California, San Diego, USA
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 2 of 7 Julio A. Urbina, Venezuelan Institute for Science Research, USA Inhibitors of T. cruzi Lipid Biosynthesis as Specific Chemotherapeutic Agents for Chagas Disease
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 3 of 7 Sylke Müller, University of Glasgow, UK Antioxidant and Redox Systems of Plasmodium – Targets for Drug Design?
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 4 of 7 R. Luise Krauth-Siegel, University of Heidelberg, Germany Enzymes of the Trypanothione Metabolism as Antitrypanosomal Drug Targets
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 5 of 7 Raymond Hui, University of Toronto, Canada Short Talk: From Osteoporosis to Cryptosporidiosis: Inhibition of Cryptosporidium parvum Farnesyl Pyrophosphate Synthase by Bisphosphonates
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 6 of 7 Silvia N. J. Moreno, University of Georgia, USA Short Talk: A Bifunctional Enzyme in the Isoprenoid Pathway of Toxoplasma gondii is the Target for Bisphosphonates
Monday, January 29 \| 8:00AM - 11:00AM Targets Room: Mountain/Lake Rooms Speaker 7 of 7 Rana Nagarkatti, FDA, USA Short Talk: Targeting the Newly Characterized Plasmodium Protein HDP that Synthesizes Hemozoin; Identification of Novel Inhibitors by High Throughput Screening
Monday, January 29 \| 9:20AM - 9:40AM Coffee Break Room: Prefunction
Monday, January 29 \| 11:00AM - 1:00PM Poster Setup Room: Bay Room
Monday, January 29 \| 1:00PM - 10:00PM Poster Viewing Room: Bay Room
Monday, January 29 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Monday, January 29 \| 5:00PM - 7:00PM Functional Genomics/Proteomics Room: Mountain/Lake Rooms Speaker 1 of 4 * Ian Street, Walter and Eliza Hall Institute of Medical Research, Australia
Monday, January 29 \| 5:00PM - 7:00PM Functional Genomics/Proteomics Room: Mountain/Lake Rooms Speaker 2 of 4 Joseph DeRisi, University of California, San Francisco, USA Global Transcription Analysis for Drug Development
Monday, January 29 \| 5:00PM - 7:00PM Functional Genomics/Proteomics Room: Mountain/Lake Rooms Speaker 3 of 4 Maria Manuel Dias da Mota, Instituto Gulbenkian Ciência, Portugal Identification of Host Factors Relevant for Malaria Infection
Monday, January 29 \| 5:00PM - 7:00PM Functional Genomics/Proteomics Room: Mountain/Lake Rooms Speaker 4 of 4 Marilyn Parsons, Seattle Biomedical Research Institute, USA Drilling Down on the Kinome of Trypanosomatids
Monday, January 29 \| 7:00PM - 8:00PM Dinner Room: Granhall
Monday, January 29 \| 7:30PM - 10:00PM Poster Session 1 Room: Bay Room
Monday, January 29 \| 8:00PM - 9:00PM Social Hour Room: Bay Room
Tuesday, January 30 \| 7:00AM - 8:00AM Breakfast Room: Granhall
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 1 of 7 * Els Torreele, Drugs for Neglected Diseases (DNDi), Switzerland
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 2 of 7 Norbert De Kimpe, Ghent University, Belgium Anti-Leishmanial Natural Products from a Medicinal Plant
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 3 of 7 Kelly Chibale, University of Cape Town, South Africa Privileged Structures and Multi-Component Reaction Strategies in Antiprotozoal Drug Discovery
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 4 of 7 H. Ulrich Göringer, Darmstadt University of Technology, Germany RNA Aptamers as Anti-Trypanosomal Agents
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 5 of 7 Dennis E. Kyle, University of Georgia, USA Artemisinin Resistance and Recrudescence Mechanisms
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 6 of 7 Karl A. Werbovetz, Ohio State University, USA Short Talk: Linear and Near-linear Diamidines with Potent Antileishmanial Activity
Tuesday, January 30 \| 8:00AM - 11:15AM Compounds Room: Mountain/Lake Rooms Speaker 7 of 7 Wayne M. Best, Murdoch University, Australia Short Talk: A Novel and Highly Potent Class of Compounds for the Treatment of Trypanosomiasis
Tuesday, January 30 \| 9:20AM - 9:40AM Coffee Break Room: Prefunction
Tuesday, January 30 \| 11:15AM - 1:00PM Poster Setup Room: Bay Room
Tuesday, January 30 \| 1:00PM - 10:00PM Poster Viewing Room: Bay Room
Tuesday, January 30 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Tuesday, January 30 \| 5:00PM - 7:00PM Screening Room: Mountain/Lake Rooms Speaker 1 of 4 * Marilyn Parsons, Seattle Biomedical Research Institute, USA
Tuesday, January 30 \| 5:00PM - 7:00PM Screening Room: Mountain/Lake Rooms Speaker 2 of 4 Ian Street, Walter and Eliza Hall Institute of Medical Research, Australia High Throughput Screening Based Drug Discovery: The Search for New and Effective Treatments for Tropical Diseases
Tuesday, January 30 \| 5:00PM - 7:00PM Screening Room: Mountain/Lake Rooms Speaker 3 of 4 James C. Sacchettini, Texas A & M University, USA Inhibition of Plasmodium falciparum Enoyl ACP Reductase as a Target for Antimalarial Drug Development
Tuesday, January 30 \| 5:00PM - 7:00PM Screening Room: Mountain/Lake Rooms Speaker 4 of 4 Jun O. Liu, Johns Hopkins University School of Medicine, USA Methionine Aminopeptidases as Antimalarial Drug Targets
Tuesday, January 30 \| 7:00PM - 8:00PM Dinner Room: Granhall
Tuesday, January 30 \| 7:30PM - 10:00PM Poster Session 2 Room: Bay Room
Tuesday, January 30 \| 8:00PM - 9:00PM Social Hour Room: Bay Room
Wednesday, January 31 \| 7:00AM - 8:00AM Breakfast Room: Granhall
Wednesday, January 31 \| 8:00AM - 11:00AM Lead Optimization Room: Mountain/Lake Rooms Speaker 1 of 5 * Kelly Chibale, University of Cape Town, South Africa
Wednesday, January 31 \| 8:00AM - 11:00AM Lead Optimization Room: Mountain/Lake Rooms Speaker 2 of 5 Jay D. Keasling, University of California, Berkeley, USA Engineering Microorganisms for Production of Artemisinin
Wednesday, January 31 \| 8:00AM - 11:00AM Lead Optimization Room: Mountain/Lake Rooms Speaker 3 of 5 Domingo Gargallo-Viola, GlaxoSmithKline, Spain Animal Models for Antimalarial Development
Wednesday, January 31 \| 8:00AM - 11:00AM Lead Optimization Room: Mountain/Lake Rooms Speaker 4 of 5 James H. McKerrow, University of California, San Diego, USA Developing Drugs for Parasitic Diseases in an Academic Incubator
Wednesday, January 31 \| 8:00AM - 11:00AM Lead Optimization Room: Mountain/Lake Rooms Speaker 5 of 5 Stephen A. Ward, Liverpool School of Tropical Medicine, UK Quinoline Animalarials Targeting the Parasites Achilles Heel
Wednesday, January 31 \| 9:20AM - 9:40AM Coffee Break Room: Prefunction
Wednesday, January 31 \| 4:30PM - 5:00PM Coffee Available Room: Prefunction
Wednesday, January 31 \| 5:00PM - 7:00PM Drug Development Room: Mountain/Lake Rooms Speaker 1 of 4 * Dennis E. Kyle, University of Georgia, USA
Wednesday, January 31 \| 5:00PM - 7:00PM Drug Development Room: Mountain/Lake Rooms Speaker 2 of 4 Richard R. Tidwell, University of North Carolina at Chapel Hill, USA Development of Diamidines for Anti-protozoal Chemotherapy
Wednesday, January 31 \| 5:00PM - 7:00PM Drug Development Room: Mountain/Lake Rooms Speaker 3 of 4 Henri Vial, Universite Montpellier II, France Development of Choline Inhibitors for Antimalarial Chemotherapy
Wednesday, January 31 \| 5:00PM - 7:00PM Drug Development Room: Mountain/Lake Rooms Speaker 4 of 4 Els Torreele, Drugs for Neglected Diseases (DNDi), Switzerland Rediscovering Nitro-Imidazoles as Promising Drug Candidates for Human African trypanosomiasis (HAT)
Wednesday, January 31 \| 7:00PM - 8:00PM Social Hour Room: Granhall
Wednesday, January 31 \| 8:00PM - 9:00PM Dinner Room: Granhall
Wednesday, January 31 \| 8:00PM - 11:00PM Entertainment Room: Granhall
Wednesday, January 31 \| 8:00PM - 11:00PM Cash Bar Room: Granhall
Thursday, February 01 \| 10:26AM - 10:26AM Departure *Session Chair.