Web Desc
Neurobiology of Addiction
Organizer(s): Stephen F. Heinemann and Eric J. Nestler
Date: February 25 - March 01, 2007
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Supported by the Director's Fund
For important information on the coronavirus, please click here
Summary of Meeting:
The meeting will cover the latest research that seeks to understand—at the basic molecular, synaptic, and systems levels—the mechanisms of addictive behavior using both animal model systems and human studies. The meeting will include a discussion of the complex neural circuitry in the brain that is involved in reward, as well as the long-lasting molecular and cellular changes and behavioral states induced by drugs of abuse.
Scholarship Deadline: October 25 2006
Discounted Abstract Deadline: October 25 2006
Abstract Deadline: November 27 2006
Discounted Registration Deadline: December 26 2006
We gratefully acknowledge the generous grant for this conference provided by:

National Institute on Drug Abuse (NIDA)
Grant No. 1R13DA022869-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, February 25 | 3:00PM - 7:30PM
Registration
Room: North Concourse


Sunday, February 25 | 6:30PM - 7:30PM
Refreshments
Room: Sunset Room


Monday, February 26 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 1 of 7
* Eric J. Nestler, Mount Sinai School of Medicine, USA

Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 2 of 7
Laura L. Peoples, University of Pennsylvania, USA
Inhibition of Accumbal Neurons: Role in Cocaine Reinforcements and Addiction

Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 3 of 7
William A. Carlezon, Jr., Harvard Medical School, USA
Role of Nucleus Accumbens CREB in Motivated Behavior: Implications for Co-Morbidity of Addiction and Depression

Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 4 of 7
Yavin Shaham, National Institutes of Health, USA
Relapse to Food Seeking: Role of CRF and PYY3-36

Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 5 of 7
Terry E. Robinson, University of Michigan, USA
Drugs, Neuroplasticity and Addiction

Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 6 of 7
Christian Lüscher, University of Geneva, Switzerland
Short Talk: Reversing Cocaine-Induced Synaptic Plasticity in the Ventral Tegmental Area

Monday, February 26 | 8:00AM - 11:15AM
Neural Circuitry of Reward
Room: Anasazi Ballroom

Speaker 7 of 7
Heinz Steiner, RFUMS/Chicago Medical School, USA
Short Talk: Cocaine Effects on Motor Learning in a Novel Running-Wheel Motor-Learning Paradigm

Monday, February 26 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Monday, February 26 | 11:15AM - 1:00PM
Poster Setup
Room: Sunset Room


Monday, February 26 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room


Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 1 of 9
* Lorna W. Role, Stony Brook University, USA

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 2 of 9
Michela Marinelli, Rosalind Franklin University of Medicine & Science, USA
Greater Excitability of Midbrain Dopamine Cells in Adolescent vs. Adult Rats

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 3 of 9
Q. David Walker, Duke University, USA
Cocaine Elicits Enhanced Behavioral and Dopamine Responses in Prepubertal and Castrated Rats

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 4 of 9
Linda P. Dwoskin, University of Kentucky, USA
Environmental Enrichment Alters Dopamine Transporter and Vesicular Monoamine Transporter Function and Cellular Localization in Medial Prefrontal Cortex

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 5 of 9
Bruce H. Mandt, University of Colorado, Denver Health Sciences Center, USA
Individual Differences in Locomotor Response and Rapid Cocaine-Induced Regulation of the Striatal Dopamine Transporter

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 6 of 9
Yancy Ferrer Acosta, University of Puerto Rico, USA
Novelty and Cocaine Intake: A New Role for CREB within the Nuclues Accumbens?

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 7 of 9
Tiziana Rubino, University of Insubria, Italy
Adolescent THC Exposure Induces Mood Alterations in Adulthood: Behavioural and Neurochemical Evidences

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 8 of 9
Bethany R. Brookshire, Wake Forest University Health Sciences, USA
Long-Term Methylphenidate Exposure Changes Dopamine/Serotonin Interactions

Monday, February 26 | 2:30PM - 4:30PM
Workshop 1: Focus on Vulnerability States
Room: Anasazi Ballroom

Speaker 9 of 9
David M. Dietz, Florida State University, USA

Monday, February 26 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Monday, February 26 | 5:00PM - 7:00PM
Neurophysiology and Synaptic Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 1 of 5
* Peter W. Kalivas, Medical University of South Carolina, USA

Monday, February 26 | 5:00PM - 7:00PM
Neurophysiology and Synaptic Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 2 of 5
Robert C. Malenka, Stanford University School of Medicine, USA
Distinct Function and Plasticity at Striatal Direct and Indirect Pathway Synapses

Monday, February 26 | 5:00PM - 7:00PM
Neurophysiology and Synaptic Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 3 of 5
Julie A. Kauer, Brown University, USA
LTP of GABAergic Synapses on Dopamine Neurons of the VTA

Monday, February 26 | 5:00PM - 7:00PM
Neurophysiology and Synaptic Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 4 of 5
Lorna W. Role, Stony Brook University, USA
Synaptic Actions of Nicotine

Monday, February 26 | 5:00PM - 7:00PM
Neurophysiology and Synaptic Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 5 of 5
Mark J. Thomas, University of Minnesota, USA
Short Talk: Experience-Elicited Synaptic Plasticity in the Nucleus Accumbens: Bidirectional Control by Cocaine

Monday, February 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Monday, February 26 | 7:30PM - 10:00PM
Poster Session 1
Room: Sunset Room


Tuesday, February 27 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Tuesday, February 27 | 8:00AM - 11:00AM
Molecular Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 1 of 6
* Stephen F. Heinemann, The Salk Institute, USA

Tuesday, February 27 | 8:00AM - 11:00AM
Molecular Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 2 of 6
Peter W. Kalivas, Medical University of South Carolina, USA
Cocaine-induced Adaptations in Glutamatergic Function

Tuesday, February 27 | 8:00AM - 11:00AM
Molecular Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 3 of 6
Julie A. Blendy, University of Pennsylvania, USA
CREB Family Transcription Factors and Addiction

Tuesday, February 27 | 8:00AM - 11:00AM
Molecular Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 4 of 6
Eric J. Nestler, Mount Sinai School of Medicine, USA
DeltaFosB and Chromatin Remodeling: Mechanisms of Long-Lasting Adaptations in Brain

Tuesday, February 27 | 8:00AM - 11:00AM
Molecular Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 5 of 6
Kelly L. Conrad, Rosalind Franklin University, USA
Short Talk: AMPA Receptor Trafficking in the Nucleus Accumbens in Rats that Display a Time-Dependent Increase in Cocaine-Seeking Behavior

Tuesday, February 27 | 8:00AM - 11:00AM
Molecular Plasticity to Drugs of Abuse
Room: Anasazi Ballroom

Speaker 6 of 6
Paul G. Mermelstein, University of Minnesota, USA
Short Talk: Dopaminergic Regulation of NFAT-Dependent Gene Expression in Striatum

Tuesday, February 27 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Tuesday, February 27 | 11:00AM - 1:00PM
Poster Setup
Room: Sunset Room


Tuesday, February 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room


Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 1 of 8
* Julie A. Blendy, University of Pennsylvania, USA

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 2 of 8
Nicole M. Avena, Princeton University, USA
Can Sugar be “Addictive”?

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 3 of 8
Sarah F. Leibowitz, Rockefeller University, USA
Overeating of Dietary Fat: Role of Orexigenic Peptides in a Vicious Cycle

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 4 of 8
Stephanie L. Borgland, University of British Columbia, Canada
Orexin/Hypocretin Signaling is Important for Highly Motivational Substances

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 5 of 8
Stephanie E. Fulton, University of Montreal, Canada
Influence of Leptin on Mesoaccumbens Dopamine Signaling and Function

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 6 of 8
Jacqueline F. McGinty, Medical University of South Carolina, USA
Relapse to Cocaine Seeking Increases BDNF and Immediate Early Gene Expression in the Prefrontal and Orbitofrontal Cortices of Abstinent Rats

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 7 of 8
Charles Chavkin, University of Washington, USA
Stress-Induced Reinstatement of Cocaine-Craving is Mediated by the Dynorphin-Kappa Opioid System: Further Analysis of the Molecular Mechanisms and Anatomical Sites of Action

Tuesday, February 27 | 2:30PM - 4:30PM
Workshop 2: Part 1, Focus on Feeding and Addiction Part 2,
Focus on BDNF/Dynorphin
Room: Anasazi Ballroom

Speaker 8 of 8
Marian L. Logrip, University of California, San Francisco, USA
Dynorphin Is a Key Downstream Effector of the Homeostatic Regulation of Ethanol Consumption by BDNF

Tuesday, February 27 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Tuesday, February 27 | 5:00PM - 7:00PM
Addiction in Model Organisms
Room: Anasazi Ballroom

Speaker 1 of 5
* Charles Chavkin, University of Washington, USA

Tuesday, February 27 | 5:00PM - 7:00PM
Addiction in Model Organisms
Room: Anasazi Ballroom

Speaker 2 of 5
Amy W. Lasek, University of California, San Francisco, USA
Of Flies and Mice: Roles of LMO’s in Cocaine-Induced Behavior

Tuesday, February 27 | 5:00PM - 7:00PM
Addiction in Model Organisms
Room: Anasazi Ballroom

Speaker 3 of 5
Michael Carvan, University of Wisconsin-Milwaukee, USA
The Identification of Genes in Zebrafish that Influence Responses to Substances of Abuse

Tuesday, February 27 | 5:00PM - 7:00PM
Addiction in Model Organisms
Room: Anasazi Ballroom

Speaker 4 of 5
Steve L. McIntire, Gallo Center, University of California San Francisco, USA
A Genetic Analysis of Ethanol Sensitivity and Tolerance in C. elegans

Tuesday, February 27 | 5:00PM - 7:00PM
Addiction in Model Organisms
Room: Anasazi Ballroom

Speaker 5 of 5
Melisa J. Wallace, University of California, San Francisco, USA
Short Talk: Protien Kinase C-epsilon Regulates Acute Behavioral Responses to Cannabinoids

Tuesday, February 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Tuesday, February 27 | 7:30PM - 10:00PM
Poster Session 2
Room: Sunset Room


Wednesday, February 28 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 1 of 7
* Cynthia Kuhn, Duke University Medical Center, USA

Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 2 of 7
Trevor W. Robbins, University of Cambridge, UK
Causes and Consequences of Addiction to Stimulants: Experimental Studies of Vulnerability and Cognitive Sequelae

Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 3 of 7
Ann E. Kelley, University of Wisconsin, Madison, USA
Neural Systems Governing Natural Rewards: Focus on Corticostriatal-Hypothalamic Integration

Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 4 of 7
George F. Koob, National Institute on Alcohol Abuse and Alcoholism, USA
Reward and Anti- Reward: The Neural Basis of the Dark Side of Addiction

Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 5 of 7
David W. Self, University of Texas Southwestern Medical Center, USA
Mechanisms of D2 Receptor Sensitization in Drug Relapse

Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 6 of 7
Ajna Hamidovic, University of Chicago, USA
Short Talk: The Role of Dopamine D2/D3 Receptor Agonist Pramipexole on Impulsivity

Wednesday, February 28 | 8:00AM - 11:15AM
Behavior States and Models
Room: Anasazi Ballroom

Speaker 7 of 7
Nicholas E. Goeders, Louisiana State University Health Sciences Center, USA
Short Talk: Combination Pharmacotherapy Targeting the HPA Axis Decreases Intravenous Cocaine Self-Administration in Rats

Wednesday, February 28 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Wednesday, February 28 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Wednesday, February 28 | 5:00PM - 7:00PM
Clinical Studies: Circuits, Genes and Phenotypes in Human Ad
dicts

Room: Anasazi Ballroom

Speaker 1 of 4
* Howard L. Fields, University of California, San Francisco, USA

Wednesday, February 28 | 5:00PM - 7:00PM
Clinical Studies: Circuits, Genes and Phenotypes in Human Ad
dicts

Room: Anasazi Ballroom

Speaker 2 of 4
Frank Telang, Brookhaven National Laboratory, USA
Neural Circuitry of Addiction in Humans

Wednesday, February 28 | 5:00PM - 7:00PM
Clinical Studies: Circuits, Genes and Phenotypes in Human Ad
dicts

Room: Anasazi Ballroom

Speaker 3 of 4
Hans Breiter, Massachusetts General Hospital, USA
Imaging Drug and Natural Reward in Humans

Wednesday, February 28 | 5:00PM - 7:00PM
Clinical Studies: Circuits, Genes and Phenotypes in Human Ad
dicts

Room: Anasazi Ballroom

Speaker 4 of 4
David Goldman, NIAAA, National Institutes of Health, USA
Genetics of Human Addictions

Wednesday, February 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Wednesday, February 28 | 8:00PM - 11:00PM
Entertainment
Room: Eldorado Court/Sunset Room


Wednesday, February 28 | 8:00PM - 11:00PM
Cash Bar
Room: Eldorado Court/Sunset Room


Thursday, March 01 | 10:21AM - 10:21AM
Departure


*Session Chair
†Invited, not yet responded.