Web Desc
MicroRNA and Cancer
Organizer(s): Gregory J. Hannon, Carlo M. Croce and Scott Hammond
Date: June 08 - 12, 2007
Location: Keystone Resort, Keystone, CO, USA
Supported by the Director's Fund
Summary of Meeting:
To date, most studies of the genetic mutations that contribute to tumor formation have focused on alterations in the sequence, gene structure, copy number and expression of protein coding genes. However, we find increasingly that the genome generates a diversity of non-coding RNAs, many of which have unknown functions. MicroRNAs act through the RNAi pathway to regulate the expression of protein coding genes, which they recognize through complementary base pairing. Accumulating data suggests causal roles for microRNAs in human cancer, including observations of microRNA genes at tumor-associated chromosomal lesions and direct demonstrations that altered expression of microRNAs can accelerate tumor development. Analysis of microRNA expression signatures may contribute to cancer diagnosis, and microRNAs themselves are potential targets for cancer therapy. This meeting will highlight emerging roles of microRNAs in tumorigenesis and place these in the context of microRNAs biochemistry and biology. Bringing together investigators from two distinct fields, namely RNA and cancer biology, will facilitate new ideas regarding the means by which microRNAs impact tumor initiation and progression.
Scholarship Deadline: February 8 2007
Discounted Abstract Deadline: February 8 2007
Abstract Deadline: March 12 2007
Discounted Registration Deadline: April 9 2007
We gratefully acknowledge additional support for this conference from:
EMD MilliporeExiqon A/Sfebit inc.Integrated DNA Technologies
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Agilent Technologies

EMBO Young Investigator Programme
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Friday, June 08 | 3:00PM - 7:30PM
Registration
Room: Shavano Peak Foyer


Friday, June 08 | 6:30PM - 7:30PM
Refreshments
Room: Shavano Peak Foyer


Saturday, June 09 | 7:00AM - 8:00AM
Breakfast
Room: Crestone/Red Cloud


Saturday, June 09 | 8:00AM - 11:00AM
Small RNA Biology
Room: Shavano Peak

Speaker 1 of 4
* Gregory J. Hannon, University of Cambridge, UK

Saturday, June 09 | 8:00AM - 11:00AM
Small RNA Biology
Room: Shavano Peak

Speaker 2 of 4
Thomas R. Gingeras, Cold Spring Harbor Laboratory, USA
Genome-Wide Maps of the Human Transcriptome Reveal an Interleaved Organization and Novel Short and Long Classes of RNAs

Saturday, June 09 | 8:00AM - 11:00AM
Small RNA Biology
Room: Shavano Peak

Speaker 3 of 4
Amy E. Pasquinelli, University of California, San Diego, USA
Regulation of Gene Expression by MicroRNAs

Saturday, June 09 | 8:00AM - 11:00AM
Small RNA Biology
Room: Shavano Peak

Speaker 4 of 4
Andrew Grimson, Whitehead Institute for Biomedical Research, USA
miRNA Targeting: Determinants Beyond Seed Pairing

Saturday, June 09 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer


Saturday, June 09 | 11:00AM - 1:00PM
Poster Setup
Room: Crestone/Red Cloud


Saturday, June 09 | 1:00PM - 8:00PM
Poster Viewing
Room: Crestone/Red Cloud


Saturday, June 09 | 2:30PM - 3:00PM
Coffee Available
Room: Shavano Peak Foyer


Saturday, June 09 | 3:00PM - 5:15PM
Measuring microRNA Expression
Room: Shavano Peak

Speaker 1 of 6
* Scott M. Hammond, University of North Carolina at Chapel Hill, USA

Saturday, June 09 | 3:00PM - 5:15PM
Measuring microRNA Expression
Room: Shavano Peak

Speaker 2 of 6
Hui Wang, Agilent Technologies, Inc., USA
Direct and Sensitive miRNA Profiling from Low-Input Total RNA

Saturday, June 09 | 3:00PM - 5:15PM
Measuring microRNA Expression
Room: Shavano Peak

Speaker 3 of 6
Martina U. Muckenthaler, Children's Hospital, University of Heidelberg, Germany
MiChip: A Microarray Platform for Expression Profiling of microRNAs Based on Locked-Nucleic Acid (LNA) Oligonucleotide Capture Probes

Saturday, June 09 | 3:00PM - 5:15PM
Measuring microRNA Expression
Room: Shavano Peak

Speaker 4 of 6
Keld Sorensen, Siemens Healthcare, USA
Short Talk: High Throughput microRNA Expression Profiling Using a Bead Based Multiplex System

Saturday, June 09 | 3:00PM - 5:15PM
Measuring microRNA Expression
Room: Shavano Peak

Speaker 5 of 6
Caifu Chen, Life Technologies, USA
MicroRNA Expression Profiling from Single Cells using Multiplex PreAmp TaqMan® MicroRNA Assays

Saturday, June 09 | 3:00PM - 5:15PM
Measuring microRNA Expression
Room: Shavano Peak

Speaker 6 of 6
Andy Bader, Mirna Therapeutics Inc., USA
Clinical Applications of miRNAs

Saturday, June 09 | 5:15PM - 6:15PM
Social Hour with Lite Bites
Room: Crestone/Red Cloud


Saturday, June 09 | 5:30PM - 8:00PM
Poster Session 1
Room: Crestone/Red Cloud


Sunday, June 10 | 7:00AM - 8:00AM
Breakfast
Room: Crestone/Red Cloud


Sunday, June 10 | 8:00AM - 11:00AM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 1 of 6
* Joshua T. Mendell, University of Texas Southwestern Medical Center, USA

Sunday, June 10 | 8:00AM - 11:00AM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 2 of 6
Scott M. Hammond, University of North Carolina at Chapel Hill, USA
MicroRNA Expression in Cancer

Sunday, June 10 | 8:00AM - 11:00AM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 3 of 6
Lin He, University of California, Berkeley, USA
A microRNA Component of the p53 Tumor Suppressor Network

Sunday, June 10 | 8:00AM - 11:00AM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 4 of 6
Carlo M. Croce, Ohio State University, USA
MicroRNAs as oncogenes and tumor suppressors

Sunday, June 10 | 8:00AM - 11:00AM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 5 of 6
Christine Mayr, Memorial Sloan Kettering Cancer Center, USA
Short Talk: let-7 Represses Hmga2 to Prevent Human Tumors

Sunday, June 10 | 8:00AM - 11:00AM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 6 of 6
Katia Basso, Columbia University, USA
Short Talk: Identification of Normal and Neoplastic Human Mature B Cells “miRome”

Sunday, June 10 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer


Sunday, June 10 | 11:00AM - 1:00PM
Poster Setup
Room: Crestone/Red Cloud


Sunday, June 10 | 1:00PM - 8:00PM
Poster Viewing
Room: Crestone/Red Cloud


Sunday, June 10 | 2:30PM - 3:00PM
Coffee Available
Room: Shavano Peak Foyer


Sunday, June 10 | 3:00PM - 5:00PM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 1 of 5
* Carlo M. Croce, Ohio State University, USA

Sunday, June 10 | 3:00PM - 5:00PM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 2 of 5
Reuven Agami, Netherlands Cancer Institute, Netherlands
EMBO Young Investigator Lecture: MicroRNAs as Oncogenes

Sunday, June 10 | 3:00PM - 5:00PM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 3 of 5
Sakari Kauppinen, Aalborg University, Denmark
Antagonizing microRNAs for Therapeutics

Sunday, June 10 | 3:00PM - 5:00PM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 4 of 5
Joshua T. Mendell, University of Texas Southwestern Medical Center, USA
Reprogramming of MicroRNA Expression by Oncogenes and Tumor Suppressors

Sunday, June 10 | 3:00PM - 5:00PM
MicroRNAs and Cancer
Room: Shavano Peak

Speaker 5 of 5
Marcus E. Peter, University of Chicago, USA
Short Talk: Reduced Let-7 Expression is a Marker for CD95 Type I Cells Representing More Advanced and Less Differentiated Stages of Cancer

Sunday, June 10 | 5:00PM - 6:00PM
Social Hour with Lite Bites
Room: Crestone/Red Cloud


Sunday, June 10 | 5:30PM - 8:00PM
Poster Session 2
Room: Crestone/Red Cloud


Monday, June 11 | 7:00AM - 8:00AM
Breakfast
Room: Crestone/Red Cloud


Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 1 of 7
* Frank J. Slack, BIDMC Cancer Center/Harvard Medical School, USA

Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 2 of 7
Klaus Rajewsky, Max Delbrück Center for Molecular Medicine, Germany
MicroRNA Control in Lymphocytes

Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 3 of 7
Antonio J. Giraldez, Yale University School of Medicine, USA
MicroRNAs in Vertebrate Development

Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 4 of 7
Antony Rodriguez, Baylor College of Medicine, USA
Short Talk: miR-155/bic is Essential for Normal Immune Function in Mice

Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 5 of 7
María José Bueno, Universidad Autónoma de Madrid, Spain
Short Talk: Genetic and Epigenetic Silencing of miR-203 Enhances ABL1 Oncogene Expresión in Hematopoietic Malignancies

Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 6 of 7
Sarah Kathryn Fineberg, University of Iowa, USA
Short Talk: miR-34a Modulates Neural Progenitor Cell Differentiation

Monday, June 11 | 8:00AM - 11:00AM
MicroRNAs in Development
Room: Shavano Peak

Speaker 7 of 7
Rui Yi, University of Colorado Boulder, USA
Short Talk: Functional Study of a Skin Specific microRNA in Embryonic Skin Development

Monday, June 11 | 9:20AM - 9:40AM
Coffee Break
Room: Shavano Peak Foyer


Monday, June 11 | 2:30PM - 3:00PM
Coffee Available
Room: Shavano Peak Foyer


Monday, June 11 | 3:00PM - 5:00PM
MicroRNAs in Cancer
Room: Shavano Peak

Speaker 1 of 5
* Carlo M. Croce, Ohio State University, USA

Monday, June 11 | 3:00PM - 5:00PM
MicroRNAs in Cancer
Room: Shavano Peak

Speaker 2 of 5
Andrea Ventura, Memorial Sloan Kettering Cancer Center, USA
On the Role of microRNAs in Mouse Development and Cancer

Monday, June 11 | 3:00PM - 5:00PM
MicroRNAs in Cancer
Room: Shavano Peak

Speaker 3 of 5
Frank J. Slack, BIDMC Cancer Center/Harvard Medical School, USA
MicroRNAs in development and cancer

Monday, June 11 | 3:00PM - 5:00PM
MicroRNAs in Cancer
Room: Shavano Peak

Speaker 4 of 5
Bill Piu Wong, Stanford University, USA
Short Talk: miR-142 is a Novel Collaborating Oncogene in Haematological Malignancies

Monday, June 11 | 3:00PM - 5:00PM
MicroRNAs in Cancer
Room: Shavano Peak

Speaker 5 of 5
Christopher Y. Park, NYU School of Medicine, USA
Short Talk: miRNA Expression Profiling of Human Acute Myeloid Leukemia Reveals a Leukemia Stem Cell Signature

Monday, June 11 | 6:00PM - 7:00PM
Social Hour with Lite Bites
Room: Gazebo


Monday, June 11 | 6:00PM - 9:00PM
Entertainment
Room: Gazebo


Monday, June 11 | 6:00PM - 9:00PM
Cash Bar
Room: Gazebo


Tuesday, June 12 | 10:26AM - 10:26AM
Departure


*Session Chair.