Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
There are no records.

Web Desc
Imaging Immune Responses joint with Intracellular and Intercellular Signaling in Dendritic Cell Function Organizer(s): Ronald N. Germain and Ellen A. Robey Date: February 25 - March 01, 2007 Location: Keystone Resort, Keystone, CO, USA Supported by the Director's Fund Summary of Meeting: The cellular events leading to host defense and immunopathology are dynamic in nature and involve the migration, transient arrest, and redistribution of various hematopoietic cells types between blood, secondary lymphoid organs, and peripheral tissues. For this reason, a great deal of excitement has been generated by the recent application of miniaturized versions of clinical imaging tools such as PET scanning and MRI, confocal and especially multiphoton microscopy, and luminescence imaging to living animals, permitting direct spatiotemporal analysis of immune cells within complex tissue environments. However, standards for data analysis and interpretation are just emerging, as are improved methods that bridge the resolution and time gaps between the various methods, allowing analyses to begin with initiation of a response and to follow it through to pathogen/tumor clearance or induction of autoimmune pathology. This meeting will bring together experts who will describe ongoing and future applications of these new imaging methods and provide the attendees with an understanding of the new biological paradigms that are emerging from such investigations. Speakers will discuss both basic and clinically-related advances, including cell-cell interactions in the development of humoral and cell-mediated immune responses, the events underlying autoimmune pathology in models of rheumatoid arthritis and diabetes, the trafficking of hematopoietic stem cells following grafting, signaling events in the thymus, bone marrow, and secondary lymphoid tissues, the sites of Treg activity, and the interplay between tumor cell growth and immune cell effector activity following anti-cancer vaccination. Scholarship Deadline: October 25 2006 Discounted Abstract Deadline: October 25 2006 Abstract Deadline: November 27 2006 Discounted Registration Deadline: December 26 2006 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI074292-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Imaging Immune Responses

joint with Intracellular and Intercellular Signaling in Dendritic Cell Function

Organizer(s): Ronald N. Germain and Ellen A. Robey

Date: February 25 - March 01, 2007
Location: Keystone Resort, Keystone, CO, USA

Supported by the Director's Fund

Summary of Meeting:

The cellular events leading to host defense and immunopathology are dynamic in nature and involve the migration, transient arrest, and redistribution of various hematopoietic cells types between blood, secondary lymphoid organs, and peripheral tissues. For this reason, a great deal of excitement has been generated by the recent application of miniaturized versions of clinical imaging tools such as PET scanning and MRI, confocal and especially multiphoton microscopy, and luminescence imaging to living animals, permitting direct spatiotemporal analysis of immune cells within complex tissue environments. However, standards for data analysis and interpretation are just emerging, as are improved methods that bridge the resolution and time gaps between the various methods, allowing analyses to begin with initiation of a response and to follow it through to pathogen/tumor clearance or induction of autoimmune pathology. This meeting will bring together experts who will describe ongoing and future applications of these new imaging methods and provide the attendees with an understanding of the new biological paradigms that are emerging from such investigations. Speakers will discuss both basic and clinically-related advances, including cell-cell interactions in the development of humoral and cell-mediated immune responses, the events underlying autoimmune pathology in models of rheumatoid arthritis and diabetes, the trafficking of hematopoietic stem cells following grafting, signaling events in the thymus, bone marrow, and secondary lymphoid tissues, the sites of Treg activity, and the interplay between tumor cell growth and immune cell effector activity following anti-cancer vaccination.

Scholarship Deadline: October 25 2006

Discounted Abstract Deadline: October 25 2006

Abstract Deadline: November 27 2006

Discounted Registration Deadline: December 26 2006

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI074292-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, February 25 \| 3:00PM - 7:30PM Registration Room: Shavano Peak Foyer
Sunday, February 25 \| 6:30PM - 7:30PM Refreshments Room: Shavano Peak Foyer
Sunday, February 25 \| 7:30PM - 8:30PM Keynote Address Room: Grays Peak 2-3 Speaker 1 of 1 Scott E. Fraser, University of Southern California, USA Observing Dynamic Cell Behavior in Complex Tissues
Monday, February 26 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud
Monday, February 26 \| 8:00AM - 11:00AM Antigen Presentation and the Initiation of T Cell Responses Room: Grays Peak 2-3 Speaker 1 of 4 * Ronald N. Germain, NIAID, National Institutes of Health, USA Directed Cell-Cell Interactions in the Development of Adaptive Immunity
Monday, February 26 \| 8:00AM - 11:00AM Antigen Presentation and the Initiation of T Cell Responses Room: Grays Peak 2-3 Speaker 2 of 4 Jean M. Davoust, Hôpital Saint-Vincent-de-Paul, France Langerhans Cell Trafficking and Antigen Capture in the Skin
Monday, February 26 \| 8:00AM - 11:00AM Antigen Presentation and the Initiation of T Cell Responses Room: Grays Peak 2-3 Speaker 3 of 4 Ulrich H. Von Andrian, Harvard Medical School, USA Cell Entry and Interaction within Lymphoid Tissues
Monday, February 26 \| 8:00AM - 11:00AM Antigen Presentation and the Initiation of T Cell Responses Room: Grays Peak 2-3 Speaker 4 of 4 Marc K. Jenkins, University of Minnesota Medical School, USA Imaging Peptide:MHC II Production During the Primary Immune Response
Monday, February 26 \| 8:00AM - 11:15AM Pathogen Recognition Pathways This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 6 * Takashi Fujita, Institute for Frontier Life and Medical Sciences, Kyoto University, Japan Triggering Antiviral Responses and Cell Regulation by the Cytoplasmic RNA Helicase RIG-I
Monday, February 26 \| 8:00AM - 11:15AM Pathogen Recognition Pathways This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 6 Akira Shizuo, Osaka University, Japan TLR-Dependent and Independent Anti-Viral Responses
Monday, February 26 \| 8:00AM - 11:15AM Pathogen Recognition Pathways This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 6 Michel Gilliet, University Hospital of Lausanne, Switzerland Short Talk: Activation of Plasmacytoid Dendritic Cell Precursors by an Endogenous Peptide
Monday, February 26 \| 8:00AM - 11:15AM Pathogen Recognition Pathways This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 6 Dana Philpott, University of Toronto, Canada NOD Pathway for Pathogen Sensing
Monday, February 26 \| 8:00AM - 11:15AM Pathogen Recognition Pathways This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 6 Teunis B.H. Geijtenbeek, University of Amsterdam, Netherlands Short Talk: DC-SIGN Modulates TLR-Induced Immune Responses in Dendritic Cells through Acetylation of NF-kappaB-Subunit p65
Monday, February 26 \| 8:00AM - 11:15AM Pathogen Recognition Pathways This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 6 Caetano Reis e Sousa, Francis Crick Institute, UK Activation of DC by Yeast
Monday, February 26 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Monday, February 26 \| 11:00AM - 1:00PM Poster Setup Room: Crestone/Red Cloud
Monday, February 26 \| 1:00PM - 10:00PM Poster Viewing Room: Crestone/Red Cloud
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 1 of 8 * Mark J. Miller, Washington University School of Medicine, USA Multi-photon Imaging of Antigen Presentation During Listeria monocytogenes Infection
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 2 of 8 * Philippe Bousso, Institute Pasteur, France Cellular Orchestration of T Cell Priming In Vivo
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 3 of 8 Ann M. Haberman, Yale University School of Medicine, USA Visualization of Germinal Center B Cell Dynamics In Vivo
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 4 of 8 Sarah E. Henrickson, Children's Hospital of Philadelphia, USA T Cell Sensing of Antigen Avidity Determines the Kinetics and Character of T Cell-Dendritic Cell Interactions in Lymph Nodes
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 5 of 8 Reinhold Förster, Hannover Medical School, Germany CCR7-Ligands Stimulate the Intranodal Motility of T Lymphocytes in vivo
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 6 of 8 Joost B. Beltman, Leiden University, Netherlands Lymph Node Topology Dictates T Cell Migration Behavior
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 7 of 8 Thorsten R. Mempel, Massachusetts General Hospital, USA Conduits Mediate Antigen Transport to Follicular Dendritic Cells in Lymph Nodes
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Intravital Multiphoton Imaging Room: Grays Peak 2-3 Speaker 8 of 8 Michio Tomura, Kyoto University Graduate School of Medicine, Japan Following Cells In Vivo Using Photoconverting Protein KAEDE
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 6 * Tsuneyasu Kaisho, RIKEN Research Center for Allergy and Immunology, Japan Critical Involvement of IkappaB kinase-alpha in TLR7/9-Induced Type I IFN Production
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 6 Emmanuel Derudder, CBR Institute for Biomedical Research, USA Roles for Canonical and Alternative NF-kappaB Activation Pathways in Dendritic Cells
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 6 Esther C. de Jong, Academic Medical Center, Netherlands Non-Canonical NF-kappaB Signaling in Dendritic Cells is Required for Indoleamine 2,3-Dioxygenase (IDO) Induction and Immune Regulation
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 6 Ranjeny Thomas, University of Queensland, Australia RelB-Competent Dendritic Cells Suppress Autoimmune Inflammatory Disease
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 6 Hiromitsu Hara, Saga University, Japan CARD9 is Essential for Myeloid Cell Activation through ITAM-bearing Receptors
Monday, February 26 \| 2:30PM - 4:30PM Workshop 1: Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 6 Yen-Michael S. Hsu, University of Texas MD Anderson Cancer Center, USA CARD9 is Required for Innate Immune Responses Against Intracellular Pathogens
Monday, February 26 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Monday, February 26 \| 5:00PM - 7:00PM Intracellular Signaling by Lymphoid Cells Analyzed in situ Room: Grays Peak 2-3 Speaker 1 of 3 Mark M. Davis, Stanford University School of Medicine, USA The Role of Endogenous Peptides in T Cell Activation and Thymic Selection
Monday, February 26 \| 5:00PM - 7:00PM Intracellular Signaling by Lymphoid Cells Analyzed in situ Room: Grays Peak 2-3 Speaker 2 of 3 Richard S. Lewis, Stanford University School of Medicine, USA A Molecular Mechanism for Sustained Calcium Signaling During T Cell Activation
Monday, February 26 \| 5:00PM - 7:00PM Intracellular Signaling by Lymphoid Cells Analyzed in situ Room: Grays Peak 2-3 Speaker 3 of 3 * Doreen A. Cantrell, University of Dundee, UK Spatial/Temporal Analysis of Inositol Lipid Metabolism During T Lymphocyte Activation
Monday, February 26 \| 5:00PM - 7:00PM Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 4 Marco Colonna, Washington University School of Medicine, USA Cross Talks between TLRs and ITAM-Dependent Receptors in DC
Monday, February 26 \| 5:00PM - 7:00PM Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 4 Jürg Tschopp, University of Lausanne, Switzerland NLRs and the Inflammasome: Danger Sensing Complexes Involved in Inflammatory Diseases
Monday, February 26 \| 5:00PM - 7:00PM Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 4 You-Me Kim, KAIST, South Korea Short Talk: the Interaction Between the ER Membrane Protein UNC93B and Toll-like Receptors 3, 7, and 9 is Crucial for TLR Signaling
Monday, February 26 \| 5:00PM - 7:00PM Signaling in Pathogen Recognition This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 4 * Anne O'Garra, Francis Crick Institute, UK Molecular Mechanisms for the Regulation of IL-10 Expression in Dendritic Cells, Macrophages and T Cells
Monday, February 26 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud
Monday, February 26 \| 7:30PM - 10:00PM Poster Session 1 Room: Crestone/Red Cloud
Tuesday, February 27 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud
Tuesday, February 27 \| 8:00AM - 11:00AM B Cell Migration and the Induction of Humoral Immune Respons es Room: Grays Peak 2-3 Speaker 1 of 4 * Jason G. Cyster, HHMI/University of California, San Francisco, USA Cell Migration Dynamics During the B Cell Immune Response
Tuesday, February 27 \| 8:00AM - 11:00AM B Cell Migration and the Induction of Humoral Immune Respons es Room: Grays Peak 2-3 Speaker 2 of 4 Philippa C. Marrack, HHMI/National Jewish Health, USA The Effects of Adjuvants on B and T Cells
Tuesday, February 27 \| 8:00AM - 11:00AM B Cell Migration and the Induction of Humoral Immune Respons es Room: Grays Peak 2-3 Speaker 3 of 4 John H. Kehrl, NIAID, National Institutes of Health, USA Regulation of B Cell Motility in Lymph Nodes
Tuesday, February 27 \| 8:00AM - 11:00AM B Cell Migration and the Induction of Humoral Immune Respons es Room: Grays Peak 2-3 Speaker 4 of 4 Michel C. Nussenzweig, HHMI/Rockefeller University, USA Imaging Germinal Centers
Tuesday, February 27 \| 8:00AM - 11:15AM Cross-Talk with Other Cells This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 6 * Kenneth L. Rock, University of Massachusetts Medical School, USA How Dying Cells Alert the Immune System to Danger
Tuesday, February 27 \| 8:00AM - 11:15AM Cross-Talk with Other Cells This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 6 Laurence Zitvogel, Institut Gustave Roussy, France DC and NK Cells
Tuesday, February 27 \| 8:00AM - 11:15AM Cross-Talk with Other Cells This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 6 Vincenzo Cerundolo, University of Oxford, UK DC and NKT cells
Tuesday, February 27 \| 8:00AM - 11:15AM Cross-Talk with Other Cells This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 6 Anna M. Keller, Netherlands Cancer Institute, Netherlands Short Talk: Costimulatory Ligand CD70 is Delivered to the Immunological Synapse by Shared Intracellular Trafficking with MHC Class II
Tuesday, February 27 \| 8:00AM - 11:15AM Cross-Talk with Other Cells This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 6 Yatin M. Vyas, Children's Hospital of Pittsburgh, USA Short Talk: Antiparallel Segregation of Notch Components in the Immunological Synapse Directs Reciprocal Signaling in Allogeneic Th:DC Conjugates
Tuesday, February 27 \| 8:00AM - 11:15AM Cross-Talk with Other Cells This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 6 Yvette van Kooyk, Vrije University Medical Center, Netherlands Regulation of DC Cross Talk with other Immune Cells by C-Type Lectins and Carbohydrates
Tuesday, February 27 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Tuesday, February 27 \| 11:00AM - 1:00PM Poster Setup Room: Crestone/Red Cloud
Tuesday, February 27 \| 1:00PM - 10:00PM Poster Viewing Room: Crestone/Red Cloud
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 1 of 7 * Bridget S. Wilson, University of New Mexico Health Science Center, USA High Resolution Imaging Methods to Probe Fc[epsilon]RI Membrane Organization and Behavior
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 2 of 7 Pavel Tolar, Francis Crick Institute, UK Imaging the B-Cell Receptor Signaling in the Immunological Synapse
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 3 of 7 Carles Rentero, University of Barcelona, Spain Membrane Organization at T Cell Activation Sites and Immunological Synapse
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 4 of 7 Valarie A. Barr, NCI, National Institutes of Health, USA Cbl-Dependent Internalization of TCR-Induced, LAT-Nucleated Signaling Complexes
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 5 of 7 Aaron K. Neumann, University of New Mexico, USA Distribution and Lateral Mobility of DC-SIGN on Immature Dendritic Cells
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 6 of 7 David M. Haaland, Sandia National Laboratories, USA Hyperspectral Confocal Imaging of Live Cell Immune Response to Cytokines
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: New Technologies for Functional, High Resolution Imaging Room: Grays Peak 2-3 Speaker 7 of 7 Matthias Gunzer, Helmholtz Centre for Infection Research, Germany The Power of Single- and Multibeam 2-Photon Microscopy for High-Resolution and High-Speed Deep Tissue and Intravital Imaging
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 7 * Shannon J. Turley, Genentech, Inc., USA Presentation of Intestinal Self by Dendritic Cells and Lymph Node Stroma
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 7 Ena Ladi, University of California, Berkeley, USA Visualizing Dendritic Cell Interactions of Migrating Thymocytes in Real-time Using Two-Photon Microscopy
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 7 John P. Driver, The Jackson Laboratory, USA Activated NKT Cells Inhibit Autoimmune Diabetes Through Tolerogenic Maturation of Dendritic Cells
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 7 Flavio A. Salazar Onfray, Institute of Biomedical Sciences, Chile Functional Gap Junctions Facilitate Melanoma Antigen Cross-Presentation in Human Dendritic Cells and are Recruited to the Immunological Synapses Contributing to T Cell Activation
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 7 Lesley Ann Smyth, Kings College London, UK A Novel Pathway of Antigen Presentation by Dendritic Cells; Implications for Infectious Diseases
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 7 Payal Watchmaker, University of Pittsburgh, USA Memory CD8+ T Cells Protect Dendritic Cells from CTL-Mediated Killing: Helper Function of Memory CD8+ T Cells
Tuesday, February 27 \| 2:30PM - 4:30PM Workshop 2: Intercellular Interactions Regulating DC Functio n This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 7 of 7 Fabienne Brilot, Rockefeller University, USA NK Cell Survival Mediated Through the Regulatory Synapse With Dendritic Cells Requires IL-15Ralpha
Tuesday, February 27 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Tuesday, February 27 \| 5:00PM - 7:00PM Lymphocyte Behavior Outside the Lymph Node Room: Grays Peak 2-3 Speaker 1 of 4 * Ellen A. Robey, University of California, Berkeley, USA Cell Interactions and Migration in the Thymus
Tuesday, February 27 \| 5:00PM - 7:00PM Lymphocyte Behavior Outside the Lymph Node Room: Grays Peak 2-3 Speaker 2 of 4 Matthew F. Krummel, University of California, San Francisco, USA Visualizing Cellular Decision-Making in Lymphocytes
Tuesday, February 27 \| 5:00PM - 7:00PM Lymphocyte Behavior Outside the Lymph Node Room: Grays Peak 2-3 Speaker 3 of 4 Ute Frevert, New York University School of Medicine, USA Intravital Imaging of the Liver Phase of a Malaria Infection
Tuesday, February 27 \| 5:00PM - 7:00PM Lymphocyte Behavior Outside the Lymph Node Room: Grays Peak 2-3 Speaker 4 of 4 Mark C. Coles, University of Oxford, UK Imaging Lymphoid Tissue Development and Maturation
Tuesday, February 27 \| 5:00PM - 7:00PM DC Migration and Antigen Uptake This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 4 * Colin Watts, University of Dundee, UK Regulation of Cytoskeleton during DC Migration and Antigen Uptake
Tuesday, February 27 \| 5:00PM - 7:00PM DC Migration and Antigen Uptake This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 4 Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA TLR-Induced Gene Expression
Tuesday, February 27 \| 5:00PM - 7:00PM DC Migration and Antigen Uptake This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 4 Pierre Guermonprez, Kings College London, UK Short Talk: the IFN Inducible p47 Small GTPase IGTP is Involved in Cross-presentation by MHC Class I in Dendritic Cells
Tuesday, February 27 \| 5:00PM - 7:00PM DC Migration and Antigen Uptake This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 4 Gwendalyn J. Randolph, Washington University, USA Origins and Migratory Fate of Pulmonary Dendritic Cells
Tuesday, February 27 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud
Tuesday, February 27 \| 7:30PM - 10:00PM Poster Session 2 Room: Crestone/Red Cloud
Wednesday, February 28 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud
Wednesday, February 28 \| 8:00AM - 11:00AM Longitudinal Imaging of Immune Responses Room: Grays Peak 2-3 Speaker 1 of 5 Robert M. Hoffman, AntiCancer, Inc., USA Tri-Color Imaging of the Interaction of the Host Immune System and Tumor Cells in the Living Mouse
Wednesday, February 28 \| 8:00AM - 11:00AM Longitudinal Imaging of Immune Responses Room: Grays Peak 2-3 Speaker 2 of 5 John C. Boothroyd, Stanford University School of Medicine, USA Dissecting Virulence and Reactivation in Toxoplasmosis Using In Vivo Imaging
Wednesday, February 28 \| 8:00AM - 11:00AM Longitudinal Imaging of Immune Responses Room: Grays Peak 2-3 Speaker 3 of 5 * Chien Ho, Carnegie Mellon University, USA Recent Cellular Imaging Studies Using Nano-sized Iron Oxide Particles: A New Non-invasive Approach to Detect Cardiac Transplant Rejection by MRI
Wednesday, February 28 \| 8:00AM - 11:00AM Longitudinal Imaging of Immune Responses Room: Grays Peak 2-3 Speaker 4 of 5 Kamal M. Khanna, University of Connecticut Health Center, USA Short Talk: Imaging the Endogenous CD8 T Cell Response to Infection: From Naïve to Memory
Wednesday, February 28 \| 8:00AM - 11:00AM Longitudinal Imaging of Immune Responses Room: Grays Peak 2-3 Speaker 5 of 5 Matthias G. von Herrath, Novo Nordisk and La Jolla Institute for Allergy and Immunology, USA Short Talk: Real-Time Imaging of the Pancreas During Development of Diabetes
Wednesday, February 28 \| 8:00AM - 11:30AM DC in Tolerance/Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 6 Maries F. van den Broek, University Hospital Zurich, Switzerland In Vivo Models for Studying Peripheral Tolerance
Wednesday, February 28 \| 8:00AM - 11:30AM DC in Tolerance/Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 6 Pamela S. Ohashi, Princess Margaret Cancer Centre, Canada Signaling Molecules Modulating Tolerance and Autoimmunity
Wednesday, February 28 \| 8:00AM - 11:30AM DC in Tolerance/Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 6 Tim D. Sparwasser, Institute of Infection and Immunology, Germany Short Talk: Ovalbumin-Specific Immunity in the Absence of Dendritic Cell Activation after Depletion of Regulatory T Cells in DEREG Mice
Wednesday, February 28 \| 8:00AM - 11:30AM DC in Tolerance/Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 6 Alexander Y. Rudensky, HHMI/Memorial Sloan Kettering Cancer Center, USA Foxp3 as the Regulatory T Cell Lineage Specification Factor
Wednesday, February 28 \| 8:00AM - 11:30AM DC in Tolerance/Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 6 * Ira Mellman, Genentech, Inc., USA DC Maturation: Transformation and Function
Wednesday, February 28 \| 8:00AM - 11:30AM DC in Tolerance/Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 6 Sebastian Amigorena, Institut Curie, France Antigen Cross Presentation in Dendritic Cells
Wednesday, February 28 \| 9:20AM - 9:40AM Coffee Break Room: Shavano Peak Foyer
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 1 of 8 * Darrell J. Irvine, Massachusetts Institute of Technology, USA Imaging Dendritic Cell Chemotaxis: Chemokine-Releasing Microspheres as Vaccine Adjuvants and Tools to Analyze Directed DC Migration
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 2 of 8 Katalin Mikecz, Rush University Medical Center, USA Anti-CD44 Antibody Treatment, but not CD44 Deficiency, Dramatically Alters Leukocyte Recruitment in Inflamed Mouse Joints
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 3 of 8 Melanie P. Matheu, University of California, Irvine, USA Imaging Effector Memory T Cell Response and Suppression by Potassium Channel Blockade
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 4 of 8 Tatyana Chtanova, University of California, Berkeley, USA Visualizing the Immune Response Against T. Gondii
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 5 of 8 Heather D. Hickman, NIAID, National Institutes of Health, USA Visualization of Early Immune Interactions After Vaccinia Virus Infection In Vivo
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 6 of 8 Tomasz Zal, University of Texas MD Anderson Cancer Center, USA Dynamics of Endogenous Foxp3+ Regulatory T Cells in Subcutaneous and Metastatic Tumors
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 7 of 8 David A. Schaer, Memorial Sloan-Kettering Cancer Center, USA Imaging T Cell Responses Against Melanoma
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Immune Imaging in Translational and Clinical Set tings Room: Grays Peak 2-3 Speaker 8 of 8 Dorian B. McGavern, NINDS, National Institutes of Health, USA Visualizing the Immunotherapeutic Clearance of a Persistent Viral Infection
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 7 * William R. Heath, University of Melbourne, Australia The Role of Dendritic Cell Subsets in Naive and Memory Responses to Infection
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 7 Alice O. Kamphorst, Emory University, USA Antigen Targeting to CD8- DCs In Vivo
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 7 Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland Activation of Macrophages through Plasmacytoid Dendritic Cell-Derived Type I Interferon Secures Control of Murine Coronavirus Infection
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 7 Peter Siegfried Jähn, Milteniy Biotec GmbH, Germany Functional Dichotomy of Plasmacytoid Dendritic Cells: Specific Activation of T-Cells Versus Production of Type I Interferon
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 7 Heli Uronen-Hansson, BioInvent, Sweden Role of CD103+ DCs in the Generation of Intestinal Immune Responses
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 7 Juergen M. Ruland, Technical University of Munich, Germany CARD9 Couples Dectin-1/Syk Signaling to NF-kappaB Activation for Antifungal Immunity
Wednesday, February 28 \| 2:30PM - 4:30PM Workshop 3: Interplay between DC Subsets in Induction of Imm unity and Tolerance This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 7 of 7 Florent Ginhoux, Singapore Immunology Network, Singapore Developmental Regulation of Chemokines Expression Controls the Recruitment of Langerhans Cells Precursors to the Skin
Wednesday, February 28 \| 4:30PM - 5:00PM Coffee Available Room: Shavano Peak Foyer
Wednesday, February 28 \| 5:00PM - 7:00PM Application of Clinical Imaging Methods to Animal Models Room: Grays Peak 2-3 Speaker 1 of 3 Anna Moore, Michigan State University, USA In Vivo Imaging of Inflammation in Type 1 Diabetes
Wednesday, February 28 \| 5:00PM - 7:00PM Application of Clinical Imaging Methods to Animal Models Room: Grays Peak 2-3 Speaker 2 of 3 * Diane Mathis, Harvard Medical School, USA Imaging beta-Cell Destruction in situ
Wednesday, February 28 \| 5:00PM - 7:00PM Application of Clinical Imaging Methods to Animal Models Room: Grays Peak 2-3 Speaker 3 of 3 David Piwnica-Worms, Washington University at St. Louis, USA Molecular Imaging: Strategies to Probe Signal Transduction in Immune Responses In Vivo
Wednesday, February 28 \| 5:00PM - 7:00PM DC Instruction of Adaptive Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 4 Muriel Moser, Université Libre de Bruxelles, Belgium Injection of anti-CTLA4 mAb in primed mice induces adaptive regulatory T cells with anti-inflammatory properties
Wednesday, February 28 \| 5:00PM - 7:00PM DC Instruction of Adaptive Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 4 * Yong-Jun Liu, Sanofi, USA Th Instruction by DCs
Wednesday, February 28 \| 5:00PM - 7:00PM DC Instruction of Adaptive Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 4 Philipp Alberts, Northern Biologics, Canada Short Talk: Dendritic Cells Control the Expression of a VAMP8 Positive Membrane Compartment to Allow for Regulated IL12 Release
Wednesday, February 28 \| 5:00PM - 7:00PM DC Instruction of Adaptive Immunity This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 4 Edith Margarethe Janssen, La Jolla Institute for Allergy and Immunology, USA Viral Modification of DC Function
Wednesday, February 28 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud
Thursday, March 01 \| 8:00AM - 11:00AM DC in Autoimmunity and Allergy This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 6 Diane Mathis, Harvard Medical School, USA DC in Diabetes
Thursday, March 01 \| 8:00AM - 11:00AM DC in Autoimmunity and Allergy This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 6 Irah King, McGill University, Canada Short Talk: GM-CSF Triggers Accelerated Myelopoiesis During EAE
Thursday, March 01 \| 8:00AM - 11:00AM DC in Autoimmunity and Allergy This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 6 * Fiona M. Powrie, University of Oxford, UK Immune Regulation in the Intestine: A Balancing Act between Effector and Regulatory T Cells
Thursday, March 01 \| 8:00AM - 11:00AM DC in Autoimmunity and Allergy This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 6 Dale T. Umetsu, Genentech, Inc., USA TIM-1 and the Development of Atopy
Thursday, March 01 \| 8:00AM - 11:00AM DC in Autoimmunity and Allergy This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 6 Bart N. Lambrecht, VIB, Ghent University, Belgium DC in Asthma
Thursday, March 01 \| 8:00AM - 11:00AM DC in Autoimmunity and Allergy This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 6 Kristin V. Tarbell, Amgen, USA Short Talk: DC-Expanded, Islet-Specific, Regulatory T Cells Increase Endogenous Foxp3+ Cells and Restore Normoglycemia in Diabetic NOD Mice
Thursday, March 01 \| 10:26AM - 10:26AM Departure *Session Chair.
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 7 * Matthew L. Albert, Genentech, Inc., USA Antigen Persistence is Required for Efficient Cross-Priming of Minor Histocompatibility Antigen Specific CD8+ T Cells
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 7 Michael Y. Gerner, NIAID, National Institutes of Health, USA Defective Direct Presentation by DC Limits CD4 T Cell Help and Causes Tolerogenic Anti-Tumor CD8 T Cell Responses
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 7 Anne Hosmalin, INSERM U1016 Institut Cochin, Université Paris Descartes, France Human Plasmacytoid Dendritic Cells Perform Cross-Presentation
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 7 Cornelius Maihoefer, Ludwig Maximilians University Munich, Germany RIG-I-Ligands in Tumor Therapy
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 5 of 7 Phillip J. Sanchez, National Jewish Medical and Research Center, USA The Expression of CD70 on Dendritic Cells in vivo and its Role in Primary and Memory CD8+ T Cell Responses
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 6 of 7 Connie M. Krawczyk, Van Andel Research Institute, USA The Effect of Jagged Expression on Dendritic Cell-Mediated Th Differentiation
Thursday, March 01 \| 1:30PM - 3:30PM Workshop 4: DC in Tolerance Induction This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 7 of 7 Jan C. Dudda, Twincore, Germany The Way of Regulatory T Cells from Thymus to Periphery is Imprinted by Tissue-Specific Dendritic Cells and Crucial for the Suppression of Autoimmunity
Thursday, March 01 \| 4:00PM - 6:15PM DC in Cancer This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 4 A. Karolina Palucka, The Jackson Laboratory for Genomic Medicine, USA DCs as Vectors and Targets in Cancer Immunotherapy
Thursday, March 01 \| 4:00PM - 6:15PM DC in Cancer This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 2 of 4 Pierre G. Coulie, University of Louvain, Brussels, Belgium Possible Mechanism of Tumor Regression Following MAGE Vaccination of Melanoma Patients.
Thursday, March 01 \| 4:00PM - 6:15PM DC in Cancer This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 3 of 4 * Carl G. Figdor, Radboud University Medical Center, Netherlands DC Cell Immunotherapy: Monitoring, Migration and Targeting
Thursday, March 01 \| 4:00PM - 6:15PM DC in Cancer This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 4 of 4 Lieping Chen, Yale University, USA B7-H1/PD-1 Pathway in Immune Tolerance
Thursday, March 01 \| 6:15PM - 7:15PM Concluding Keynote Address This session is from Dendritic Cell Function Room: Shavano/Torreys Speaker 1 of 1 Ralph M. Steinman, Rockefeller University, USA Dendritic Cells and Vacine Biology