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Web Desc
Forkhead Transcription Factor Networks in Development, Signaling, and Disease Organizer(s): Kenneth S. Zaret, Klaus H. Kaestner and Susan E. Mango Date: January 13 - 17, 2008 Location: Zermatt Resort & Spa - Utah, Midway, UT, USA Supported by the Director's Fund Summary of Meeting: Forkhead box (FOX) transcription factors were discovered to bind target DNA sites in compacted chromatin, where many other transcription factors cannot bind, and subsequently found to play central roles in regulatory networks that control development, signaling, metabolism, and human disease. The proposed meeting will provide a rare opportunity for cross-fertilization of ideas from very different areas of biological sciences, spanning diverse model organisms and humans, all surrounding this special class of transcription factor. It is expected that the convergence of different models systems, approaches, and thinking will allow unique new insights and advances in each of the scientific domains in which FOXA factors are studied. Scholarship Deadline: September 12 2007 Discounted Abstract Deadline: September 12 2007 Abstract Deadline: October 15 2007 Discounted Registration Deadline: November 13 2007 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Grant No. 1R13HD057650-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Forkhead Transcription Factor Networks in Development, Signaling, and Disease

Organizer(s): Kenneth S. Zaret, Klaus H. Kaestner and Susan E. Mango

Date: January 13 - 17, 2008
Location: Zermatt Resort & Spa - Utah, Midway, UT, USA

Supported by the Director's Fund

Summary of Meeting:

Forkhead box (FOX) transcription factors were discovered to bind target DNA sites in compacted chromatin, where many other transcription factors cannot bind, and subsequently found to play central roles in regulatory networks that control development, signaling, metabolism, and human disease. The proposed meeting will provide a rare opportunity for cross-fertilization of ideas from very different areas of biological sciences, spanning diverse model organisms and humans, all surrounding this special class of transcription factor. It is expected that the convergence of different models systems, approaches, and thinking will allow unique new insights and advances in each of the scientific domains in which FOXA factors are studied.

Scholarship Deadline: September 12 2007

Discounted Abstract Deadline: September 12 2007

Abstract Deadline: October 15 2007

Discounted Registration Deadline: November 13 2007

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Grant No. 1R13HD057650-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, January 13 \| 3:00PM - 7:30PM Registration Room: Matterhorn Foyer
Sunday, January 13 \| 6:30PM - 7:30PM Refreshments Room: Matterhorn Foyer
Sunday, January 13 \| 7:30PM - 8:30PM Keynote Session Room: Matterhorn Ballroom Speaker 1 of 1 Myles Brown, Dana-Farber Cancer Institute, USA Connecting Forkhead Factors and Nuclear Receptors to the Genome
Monday, January 14 \| 7:00AM - 8:00AM Breakfast Room: Schneitter's Restaurant
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 1 of 7 * Jane Mellor, University of Oxford, UK
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 2 of 7 Susan E. Mango, Harvard University, USA Making and Shaping the Foregut in C. elegans
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 3 of 7 Peter L. J. de Keizer, UMC Utrecht, Netherlands Short Talk: The Peptidyl-Isomerase Pin1 Regulates p27kip1 Expression through Inhibition of FOXO Transcription Factors
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 4 of 7 Deborah J. Andrew, Johns Hopkins University, USA The Role of the Fox A Protein Fkh in the Drosophila Salivary Gland
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 5 of 7 Sven Enerbäck, University of Gothenburg, Sweden A Conserved Foxi1 Regulated Genetic Circuit Operates in the Ear, Kidney and Epididymis
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 6 of 7 Siew-Lan Ang, National Institute for Medical Research, UK Short Talk: Foxa1 and Foxa2 Regulate Midbrain Dopaminergic Neuron Development in a Dosage-Dependent Manner
Monday, January 14 \| 8:00AM - 11:15AM Development and Transcription Networks I Room: Matterhorn Ballroom Speaker 7 of 7 Klaus H. Kaestner, University of Pennsylvania School of Medicine, USA The Foxa Genes in the Endocrine Pancreas
Monday, January 14 \| 9:20AM - 9:40AM Coffee Break Room: Davos Break area
Monday, January 14 \| 11:15AM - 1:00PM Poster Set Up for Sessions 1 & 2 Room: Davos/ Grindelwald
Monday, January 14 \| 1:00PM - 10:00PM Poster Viewing Room: Davos/ Grindelwald
Monday, January 14 \| 4:30PM - 5:00PM Coffee Available Room: Davos Break area
Monday, January 14 \| 5:00PM - 7:00PM Chromatin Remodeling and Transcription Room: Matterhorn Ballroom Speaker 1 of 5 * Susan E. Mango, Harvard University, USA
Monday, January 14 \| 5:00PM - 7:00PM Chromatin Remodeling and Transcription Room: Matterhorn Ballroom Speaker 2 of 5 Jane Mellor, University of Oxford, UK Yeast Fkh1 and Fkh2 Factors and Chromatin Remodeling
Monday, January 14 \| 5:00PM - 7:00PM Chromatin Remodeling and Transcription Room: Matterhorn Ballroom Speaker 3 of 5 Lisa Ann Cirillo, Medical College of Wisconsin, USA Chromatin Binding and Perturbation by FoxO1
Monday, January 14 \| 5:00PM - 7:00PM Chromatin Remodeling and Transcription Room: Matterhorn Ballroom Speaker 4 of 5 David Stillman, University of Utah, USA Short Talk: Yeast Fkh1 and Fkh2 Proteins Recruit the Sin3 HDAC to Promoters and Can Block Activation By Promoter Bound Factors
Monday, January 14 \| 5:00PM - 7:00PM Chromatin Remodeling and Transcription Room: Matterhorn Ballroom Speaker 5 of 5 Kenneth S. Zaret, University of Pennsylvania, USA Distinctive Chromatin Binding and Scanning Properties of Fox Factors
Monday, January 14 \| 7:00PM - 7:15PM Discussion About the Creation of New Web Resources for Fox F actors Room: Matterhorn Ballroom Speaker 1 of 1 Klaus H. Kaestner, University of Pennsylvania School of Medicine, USA
Monday, January 14 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Davos/ Grindelwald
Monday, January 14 \| 7:30PM - 10:00PM Poster Session 1 Room: Davos/ Grindelwald
Tuesday, January 15 \| 7:00AM - 8:00AM Breakfast Room: Schneitter's Restaurant
Tuesday, January 15 \| 8:00AM - 11:00AM Metabolism and Signaling Room: Matterhorn Ballroom Speaker 1 of 6 * Deborah J. Andrew, Johns Hopkins University, USA
Tuesday, January 15 \| 8:00AM - 11:00AM Metabolism and Signaling Room: Matterhorn Ballroom Speaker 2 of 6 Heidi Tissenbaum, University of Massachusetts Medical School, USA Complex Regulation by C. elegans FOXO/Daf-16
Tuesday, January 15 \| 8:00AM - 11:00AM Metabolism and Signaling Room: Matterhorn Ballroom Speaker 3 of 6 Hyun Jung Park, University of Illinois at Chicago, USA Short Talk: Cell Cycle Regulation of the Forkhead Box M1 (FoxM1) Transcription Factor
Tuesday, January 15 \| 8:00AM - 11:00AM Metabolism and Signaling Room: Matterhorn Ballroom Speaker 4 of 6 Andrew G. Dillin, University of California, Berkeley, USA Pha4/Foxa, Diet Restriction, and Longevity
Tuesday, January 15 \| 8:00AM - 11:00AM Metabolism and Signaling Room: Matterhorn Ballroom Speaker 5 of 6 Andrei L. Gartel, University of Illinois, USA Short Talk: Thiazole Antibiotics that Inhibit FoxM1 are Potential Anticancer Drugs
Tuesday, January 15 \| 8:00AM - 11:00AM Metabolism and Signaling Room: Matterhorn Ballroom Speaker 6 of 6 Ronald D. McKay, Lieber Institute for Brain Development, USA Foxa2, Dopamine Neurons, and Parkinson's Disease
Tuesday, January 15 \| 9:20AM - 9:40AM Coffee Break Room: Davos Break area
Tuesday, January 15 \| 1:00PM - 10:00PM Poster Viewing Room: Davos/ Grindelwald
Tuesday, January 15 \| 4:30PM - 5:00PM Coffee Available Room: Davos Break area
Tuesday, January 15 \| 5:00PM - 7:00PM Structure and Evolution of Winged Helix Proteins Room: Matterhorn Ballroom Speaker 1 of 5 * Michelle C. Barton, University of Texas MD Anderson Cancer Center, USA
Tuesday, January 15 \| 5:00PM - 7:00PM Structure and Evolution of Winged Helix Proteins Room: Matterhorn Ballroom Speaker 2 of 5 Paola Oliveri, University College London, UK Fox Genes in Regulatory Networks for Embryo Development and Evolution
Tuesday, January 15 \| 5:00PM - 7:00PM Structure and Evolution of Winged Helix Proteins Room: Matterhorn Ballroom Speaker 3 of 5 Lin Chen, University of Southern California, USA Structural Insights into the Potential Role of FOXP Proteins in the Epigenetic Control of Chromatin Structure
Tuesday, January 15 \| 5:00PM - 7:00PM Structure and Evolution of Winged Helix Proteins Room: Matterhorn Ballroom Speaker 4 of 5 Xiubei Liao, University of Illinois at Chicago, USA Folding Stage Dependent Interactions Between HNF-6 and FoxD3 Hint at a Complicated Network in Transcriptional Regulation
Tuesday, January 15 \| 5:00PM - 7:00PM Structure and Evolution of Winged Helix Proteins Room: Matterhorn Ballroom Speaker 5 of 5 Michael Brent, Wistar Institute, USA Short Talk: Structure and Regulation of Human FoxO1 Transcription Factor
Tuesday, January 15 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Davos/ Grindelwald
Tuesday, January 15 \| 7:30PM - 10:00PM Poster Session 2 Room: Davos/ Grindelwald
Wednesday, January 16 \| 7:00AM - 8:00AM Breakfast Room: Schneitter's Restaurant
Wednesday, January 16 \| 8:00AM - 11:00AM The Fox Genes in Human Disease Room: Matterhorn Ballroom Speaker 1 of 6 * Klaus H. Kaestner, University of Pennsylvania School of Medicine, USA
Wednesday, January 16 \| 8:00AM - 11:00AM The Fox Genes in Human Disease Room: Matterhorn Ballroom Speaker 2 of 6 H. Phillip Koeffler, Cedars-Sinai Medical Center, USA FOXA1 and BRCA1 in Breast Cancer
Wednesday, January 16 \| 8:00AM - 11:00AM The Fox Genes in Human Disease Room: Matterhorn Ballroom Speaker 3 of 6 Michael A. Walter, University of Alberta, Canada FOXC1 in Axenfeld-Rieger-Syndrome and Glaucoma
Wednesday, January 16 \| 8:00AM - 11:00AM The Fox Genes in Human Disease Room: Matterhorn Ballroom Speaker 4 of 6 Constance Scharff, Max Planck Institute for Molecular Genetics, Germany Foxp2 in Learned Avian Vocalizations
Wednesday, January 16 \| 8:00AM - 11:00AM The Fox Genes in Human Disease Room: Matterhorn Ballroom Speaker 5 of 6 Ping Hu, University of California, Berkeley, USA Short Talk: A Dual Activator Mechanism Directs Myoblast Specific MyoD Transcription
Wednesday, January 16 \| 8:00AM - 11:00AM The Fox Genes in Human Disease Room: Matterhorn Ballroom Speaker 6 of 6 Simon E. Fisher, Oxford University, UK Neurogenetic Pathways Regulated by FOXP2, a Gene Involved in Speech and Language
Wednesday, January 16 \| 9:20AM - 9:40AM Coffee Break Room: Davos Break area
Wednesday, January 16 \| 4:30PM - 5:00PM Coffee Available Room: Davos Break area
Wednesday, January 16 \| 6:00PM - 7:00PM Development II Room: Matterhorn Ballroom Speaker 1 of 3 * Kenneth S. Zaret, University of Pennsylvania, USA
Wednesday, January 16 \| 6:00PM - 7:00PM Development II Room: Matterhorn Ballroom Speaker 2 of 3 Michelle C. Barton, University of Texas MD Anderson Cancer Center, USA Temporal Orchestration of Chromatin Regulation by Foxa1, TGFß and p53
Wednesday, January 16 \| 6:00PM - 7:00PM Development II Room: Matterhorn Ballroom Speaker 3 of 3 Peter Carlsson, Göteborg University, Sweden FoxF Genes in Murine Embryonic Development
Wednesday, January 16 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Davos/ Grindelwald
Wednesday, January 16 \| 8:00PM - 11:00PM Entertainment Room: Davos/ Grindelwald
Wednesday, January 16 \| 8:00PM - 11:00PM Cash Bar Room: Davos/ Grindelwald
Thursday, January 17 \| 10:25AM - 10:25AM Departure *Session Chair.