Tolerance in Transplantation and Autoimmunity

Organizer(s): Jeffrey A. Bluestone, Abul K. Abbas, Laurence A. Turka and Diane J. Mathis

Sponsored by Novo Nordisk A/S

Summary of Meeting:

The past 40 years has seen enormous progress in the treatment of organ transplantation and autoimmunity. However, with the modern era of immunosuppression, significant problems remain including strikingly higher rates of cardiovascular disease, opportunistic infection, and malignancy. The ability to induce immune tolerance would solve most of these problems. There has been enormous progress in our understanding of the basic processes of both central and peripheral tolerance. Moreover, the development of novel cell surface, soluble and cellular targets has created new therapeutics. The goals of this meeting will be to present cutting edge basic and clinical tolerance research related to transplantation and autoimmunity. Presentations will focus on both advances in basic understanding of immune tolerance, pre-clinical models of disease as well as far-reaching mechanistic studies devoted to the understanding of diseases and therapeutic interventions. The meeting stands out as bringing both basic science and clinical research experts together to explore the major biological pathways of tolerance at the molecular, cellular, pre-clinical and clinical levels. Thus, the meeting will promote critical interchanges between scientists who study these processes and educate students. The long-term objective is to increase our understanding of basic tenets underlying tolerance, to establish new collaborative research projects between basic and clinical researchers and to excite future scientists in this field of study.

Scholarship Deadline: October 1 2007

Discounted Abstract Deadline: October 1 2007

Abstract Deadline: November 1 2007

Discounted Registration Deadline: December 3 2007

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI075649-01

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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