Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
DNA Replication and Recombination (2017Z2)
DNA Replication and Recombination (2015X3)
DNA Replication and Recombination (2013X5)
DNA Replication and Recombination (2011C2)

Web Desc
DNA Replication and Recombination Organizer(s): Jack D. Griffith, Nancy G. Nossal (in Memoriam), Richard D. Kolodner, Charles S. McHenry and Jerard Hurwitz Date: February 10 - 15, 2008 Location: Eldorado Hotel & Spa, Santa Fe, NM, USA Supported by the Director's Fund Summary of Meeting: The Keystone Symposia “DNA Replication and Recombination” meeting, the longest standing meeting of this multi-decade series continues to meld investigators representing a range of disciplines who otherwise would not have a format for sharing novel approaches and groundbreaking discoveries. This field drives DNA sequencing technology, the design of myriad anti-viral and anti-bacterial drugs, and the development of novel strategies for gene targeting and generation of transgenic animals. Major pivotal questions include (1) the role of condensins in DNA pairing and replication fork movement, (2) mechanisms by which stalled replication forks are recognized and replication is restarted, (3) the role of recombinational mechanisms in the maintenance of telomeres in the absence of telomerase, (4) the architecture of forks and replication origins, and (5) the mechanisms by which fork initiation is timed with the cell cycle. Speakers representing established laboratories will share the podium with young investigators describing genomic, structural, and biochemical approaches to these central questions. Scholarship Deadline: October 10 2007 Discounted Abstract Deadline: October 10 2007 Abstract Deadline: November 8 2007 Discounted Registration Deadline: December 11 2007 We gratefully acknowledge additional support for this conference from: We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

DNA Replication and Recombination

Organizer(s): Jack D. Griffith, Nancy G. Nossal (in Memoriam), Richard D. Kolodner, Charles S. McHenry and Jerard Hurwitz

Date: February 10 - 15, 2008
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA

Supported by the Director's Fund

Summary of Meeting:

The Keystone Symposia “DNA Replication and Recombination” meeting, the longest standing meeting of this multi-decade series continues to meld investigators representing a range of disciplines who otherwise would not have a format for sharing novel approaches and groundbreaking discoveries. This field drives DNA sequencing technology, the design of myriad anti-viral and anti-bacterial drugs, and the development of novel strategies for gene targeting and generation of transgenic animals. Major pivotal questions include (1) the role of condensins in DNA pairing and replication fork movement, (2) mechanisms by which stalled replication forks are recognized and replication is restarted, (3) the role of recombinational mechanisms in the maintenance of telomeres in the absence of telomerase, (4) the architecture of forks and replication origins, and (5) the mechanisms by which fork initiation is timed with the cell cycle. Speakers representing established laboratories will share the podium with young investigators describing genomic, structural, and biochemical approaches to these central questions.

Scholarship Deadline: October 10 2007

Discounted Abstract Deadline: October 10 2007

Abstract Deadline: November 8 2007

Discounted Registration Deadline: December 11 2007

We gratefully acknowledge additional support for this conference from:

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, February 10 \| 3:00PM - 7:30PM Registration Room: Zia Concourse
Sunday, February 10 \| 6:30PM - 7:30PM Refreshments Room: Pavillion
Sunday, February 10 \| 7:30PM - 7:40PM Brief Introduction to the Meeting Speaker 1 of 1 * Jack D. Griffith, University of North Carolina, Chapel Hill, USA
Sunday, February 10 \| 7:40PM - 8:40PM Keynote Address Room: Anasazi Ballroom Speaker 1 of 1 Michael E. O'Donnell, Rockefeller University, USA Dynamic Mechanisms at the E. coli Replication Fork
Monday, February 11 \| 7:00AM - 8:00AM Breakfast Room: Eldorado Court
Monday, February 11 \| 8:00AM - 11:00AM Replication Fork Mechanisms Room: Anasazi Ballroom Speaker 1 of 4 * Peter M. Burgers, Washington University School of Medicine, USA Remodeling of the Replication Fork in Response to DNA Damage
Monday, February 11 \| 8:00AM - 11:00AM Replication Fork Mechanisms Room: Anasazi Ballroom Speaker 2 of 4 Thomas A. Steitz, Howard Hughes Medical Institute, Yale University, USA The Macromolecular Replication Machinery: Structural Insights into the Replisome
Monday, February 11 \| 8:00AM - 11:00AM Replication Fork Mechanisms Room: Anasazi Ballroom Speaker 3 of 4 Charles S. McHenry, University of Colorado Boulder, USA Reconstitution of a B. subtilis Rolling Circle DNA Replication System
Monday, February 11 \| 8:00AM - 11:00AM Replication Fork Mechanisms Room: Anasazi Ballroom Speaker 4 of 4 Antoine M. van Oijen, University of Wollongong, Australia Under the Hood of the Replisome: A Single-Molecule View of DNA Replication
Monday, February 11 \| 9:20AM - 9:40AM Coffee Break Room: Pavillion
Monday, February 11 \| 11:00AM - 1:00PM Poster Setup Room: Pavillion
Monday, February 11 \| 11:00AM - 11:00AM On Own for Lunch
Monday, February 11 \| 1:00PM - 10:00PM Poster Viewing Room: Pavillion
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 1 of 8 * Nicholas E. Dixon, University of Wollongong, Australia A Molecular Mousetrap Determines Polarity in Termination of E. coli DNA Replication
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 2 of 8 Alan C. Leonard, Florida Institute of Technology, USA Two Growth Rate-Dependent Mechanisms for Pre-Replication Complex Assembly in E. coli
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 3 of 8 Kenji Keyamura, Kyushu University, Japan A Novel Initiation-Stimulator DiaA Directly Promotes ATP-DnaA-Specific Initiation Complexes in E. coli
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 4 of 8 Smita S. Patel, UMDNJ-RW Johnson Medical School, USA Coordination of Helicase, Primase, and Polymerase Activities in DNA Replication
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 5 of 8 Samir M. Hamdan, King Abdullah University of Science and Technology, Saudi Arabia Two Molecular Triggers Reset the Bacteriophage T7 Replisome after Okazaki Fragment Synthesis
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 6 of 8 Isabel Kurth, Rockefeller University, USA Polymerase Collision Release is Mediated by Loss of Multiple Attachment Points to DNA upon Completing each Okazaki Fragment
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 7 of 8 Erik Johansson, Umeå University, Sweden The Eukaryotic Leading and Lagging Strand DNA Polymerases are Loaded onto Primer-Ends via Separate Mechanisms but have Comparable Processivity in the Presence of PCNA
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Origins and Okazaki Fragments Room: Anasazi Ballroom Speaker 8 of 8 Nina Y. Yao, Rockefeller University, USA Mechanism of PCNA Clamp Opening by Replication Factor C
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 1 of 8 * David J. Sherratt, University of Oxford, UK Independent positioning and action of replication forks in live Esherichia coli
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 2 of 8 Kiyoshi Mizuuchi, NIDDK, National Institutes of Health, USA P1 Plasmid Partition: Role of ATP-Dependent ParA Conformational Change and DNA Binding Kinetics in DNA Translocation
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 3 of 8 Shingo Nozaki, Nagoya University Graduate School, Japan Subcellular Localization of Escherichia coli DnaA, the Initiator of DNA Replication
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 4 of 8 Bhupender Singh, Uppsala University, Sweden Replication Factories in Live Bacteria (E. coli): Localization for Chromosomal, Viral and Plasmid Replication Sites
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 5 of 8 Amitabh Nimonkar, University of California, USA Single-Molecule Imaging & Biochemical Analysis of Saccharomyces Cerevisiae Encoded Dmc1 & Tid1/Rdh54 Proteins
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 6 of 8 Constance Nugent, University of California, Riverside, USA Analysis of Telomere Capping Protein Interactions with Polalpha Subunits
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 7 of 8 Toru Nakamura, University of Illinois at Chicago, USA Cell Cycle Regulation of Fission Yeast Telomere Proteins
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Chromosomes, Telomeres, and Large Scale Organiza tion Room: Zia Ballroom Speaker 8 of 8 Manolis Papamichos-Chronakis, Institut Curie, France The INO80 Chromatin Remodeling Enzyme Regulates Replisome Function and Stability
Monday, February 11 \| 4:30PM - 5:00PM Coffee Available Room: Pavillion
Monday, February 11 \| 5:00PM - 7:00PM Replication and Recombination at Telomeres Room: Anasazi Ballroom Speaker 1 of 3 * Jack D. Griffith, University of North Carolina, Chapel Hill, USA T-Loops and T-Circles in the Replication of Telomeres
Monday, February 11 \| 5:00PM - 7:00PM Replication and Recombination at Telomeres Room: Anasazi Ballroom Speaker 2 of 3 Julia Promisel Cooper, NCI, National Institutes of Health, USA Disentangling Chromosome Ends: The Outcome of Replication Fork Stalling at Telomeres is Dictated by Sumoylation of RecQ Helicase
Monday, February 11 \| 5:00PM - 7:00PM Replication and Recombination at Telomeres Room: Anasazi Ballroom Speaker 3 of 3 Susan M. Bailey, Colorado State University, USA Telomere Dynamics and Premature Aging
Monday, February 11 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Pavillion
Monday, February 11 \| 7:30PM - 10:00PM Poster Session 1 Room: Pavillion
Tuesday, February 12 \| 7:00AM - 8:00AM Breakfast Room: Eldorado Court
Tuesday, February 12 \| 7:00AM - 8:00AM Poster Setup Room: Pavillion
Tuesday, February 12 \| 8:00AM - 11:00AM Assembling Initiation Complexes - Replication Origins and Ce ll Cycle Control Room: Anasazi Ballroom Speaker 1 of 4 * Jerard Hurwitz, Memorial Sloan-Kettering Cancer Center, USA Initiation of Replication
Tuesday, February 12 \| 8:00AM - 11:00AM Assembling Initiation Complexes - Replication Origins and Ce ll Cycle Control Room: Anasazi Ballroom Speaker 2 of 4 Louise T. Chow, University of Alabama at Birmingham, USA Regulation of Human Papillomavirus DNA Replication
Tuesday, February 12 \| 8:00AM - 11:00AM Assembling Initiation Complexes - Replication Origins and Ce ll Cycle Control Room: Anasazi Ballroom Speaker 3 of 4 Bruce W. Stillman, Cold Spring Harbor Laboratory, USA Control of the Chromosome Cycle in Human Cells by the Origin Recognition Complex
Tuesday, February 12 \| 8:00AM - 11:00AM Assembling Initiation Complexes - Replication Origins and Ce ll Cycle Control Room: Anasazi Ballroom Speaker 4 of 4 John F.X. Diffley, Francis Crick Institute, UK Regulation of Replication Origin Activation during the Cell Cycle and in Response to DNA Damage
Tuesday, February 12 \| 9:20AM - 9:40AM Coffee Break Room: Pavillion
Tuesday, February 12 \| 11:00AM - 12:00PM Lunch Room: Pavillion
Tuesday, February 12 \| 12:00PM - 2:30PM Poster Session 2 Room: Pavillion
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 1 of 8 * Laurie S. Kaguni, Michigan State University, USA Modular Architecture and Human Disease Alleles of the Mitochondrial Replicative DNA Helicase
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 2 of 8 Amy Marion Branagan, University of Vermont, USA Intermediates in Gp59-Mediated Helicase Loading at the T4 DNA Replication Fork
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 3 of 8 Ajit Kumar Satapathy, Harvard Medical School, USA Nucleotide and Metal Cofactor Specificity in Bacteriophage T7 Helicase
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 4 of 8 Whitney Yin, University of Texas, Austin, USA Crystal Structure of Human Miochondrial DNA Polymerase Holoenzyme
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 5 of 8 Robert A. Sclafani, University of Colorado Denver, USA Structure-Function Analysis of DNA Binding Domains in Mcm DNA Helicases
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 6 of 8 Matthew L. Bochman, Indiana University, USA Involvement of an ATP-Dependent “Gate” in MCM2-7 Helicase Activity
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 7 of 8 Megan Davey, University of Western Ontario, Canada A Ringmaker Mechanism for Loading MCMs onto DNA
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 3: Helicases, Mitochondrial Replication Room: Anasazi Ballroom Speaker 8 of 8 Jaya G. Yodh, University of Illinois at Urbana-Champaign, USA Single Molecule Analysis of DNA Unwinding by Human Bloom Helicase
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 1 of 9 * Johannes C. Walter, Harvard Medical School, USA
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 2 of 9 Chrystelle Maric Antoinat, Institut Andre Lwoff, France X-Shaped Post-Replicative Joint DNA Molecules Contain Ribonucleotides
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 3 of 9 Francesca Storici, Georgia Institute of Technology, USA RNA-Templated DNA Repair
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 4 of 9 Benedicte Michel, CNRS, France Ruva Mutants that Resolve Holliday Junctions but do not Revert Replication Forks
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 5 of 9 Kent W. Mouw, Dana-Farber Cancer Institute, USA Architecture of a Serine Recombinase – DNA Regulatory Complex
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 6 of 9 Yasuto Murayama, Yokohama City University, Japan Fission Yeast Rhp51 Recombinase Promotes DNA Four-Strand Exchange Reaction in vitro
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 7 of 9 Sapna Das-Bradoo, Northeastern State University, USA How do Cells Sense DNA Damage “Behind” the Fork?
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 8 of 9 Kristina Trenz, London Research Institute, Clare Hall, UK Plx1 is Required for Chromosomal DNA Replication under Stressful Conditions
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Recombination and Repair in Yeast and Prokaryote s Room: Zia Ballroom Speaker 9 of 9 Audrey J. Klingele, Proteovista LLC, USA Changes in Gene Expression Related to Acquired Resistance to Radiation Damage
Tuesday, February 12 \| 4:30PM - 5:00PM Coffee Available Room: Pavillion
Tuesday, February 12 \| 5:00PM - 7:00PM Recombination Mechanisms and Chromosome Pairing Room: Anasazi Ballroom Speaker 1 of 3 * Kirill S. Lobachev, Georgia Institute of Technology, USA Mechanisms of Chromosomal Fragility and Genome Rearrangements Mediated by Unstable Repeats
Tuesday, February 12 \| 5:00PM - 7:00PM Recombination Mechanisms and Chromosome Pairing Room: Anasazi Ballroom Speaker 2 of 3 Eric C. Greene, Columbia University, USA Visualizing DNA Repair Proteins in Action
Tuesday, February 12 \| 5:00PM - 7:00PM Recombination Mechanisms and Chromosome Pairing Room: Anasazi Ballroom Speaker 3 of 3 Camilla Sjögren, Karolinska Institutet, Sweden Sister Chromatid Cohesion in Chromosome Segregation and Repair
Tuesday, February 12 \| 7:00PM - 7:00PM On Own for Dinner
Wednesday, February 13 \| 7:00AM - 8:00AM Breakfast Room: Eldorado Court
Wednesday, February 13 \| 8:00AM - 11:00AM Architecture of Replication and Recombination Complexes Room: Anasazi Ballroom Speaker 1 of 4 * Stephen C. West, Francis Crick Institute, UK Aprataxin — A Proofreader for Abortive DNA Ligation Events
Wednesday, February 13 \| 8:00AM - 11:00AM Architecture of Replication and Recombination Complexes Room: Anasazi Ballroom Speaker 2 of 4 Johannes C. Walter, Harvard Medical School, USA Mechanism of DNA Interstrand Crosslink Repair
Wednesday, February 13 \| 8:00AM - 11:00AM Architecture of Replication and Recombination Complexes Room: Anasazi Ballroom Speaker 3 of 4 Fred Dyda, NIDDK, National Institutes of Health, USA Molecular Mechanism of Asymmetric DNA Transposition
Wednesday, February 13 \| 8:00AM - 11:00AM Architecture of Replication and Recombination Complexes Room: Anasazi Ballroom Speaker 4 of 4 James M. Berger, Johns Hopkins University School of Medicine, USA Molecular Mechanisms for Initiating DNA Replication
Wednesday, February 13 \| 9:20AM - 9:40AM Coffee Break Room: Pavillion
Wednesday, February 13 \| 11:00AM - 1:00PM Poster Setup Room: Pavillion
Wednesday, February 13 \| 11:00AM - 11:00AM On Own for Lunch
Wednesday, February 13 \| 1:00PM - 10:00PM Poster Viewing Room: Pavillion
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 1 of 9 * Kyungjae Myung, Institute for Basic Science, South Korea
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 2 of 9 Elena Curti, NICHD, National Institutes of Health, USA Interplay of E. coli Polymerases during Genome Duplication
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 3 of 9 Anne-Marie MacLean McRobbie, University of St Andrews, UK Understanding the Interplay between Recombinases, Helicases and DNA Binding Proteins during Homologous Recombination in Archaea
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 4 of 9 Danielle L. Daee, USA Functional Consequences of Replicative Polymerase Polymorphisms and Cancer-Associated Mutations Modeled in Yeast
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 5 of 9 Daniel Kane, Tufts University, USA Usage of DNA Polymerase Eta and Zeta in Homologous Recombination and Repair following DNA Damage in Drosophila
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 6 of 9 Mitch McVey, Tufts University, USA DNA Polymerase Theta Functions in an Alternative Double-Strand Break Repair Pathway in Drosophila Melanogaster
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 7 of 9 Nilabja Sikdar, National Human Genome Research Institute, USA Human ELG1 Functions to Repair DNA Damage through its Interaction with PCNA and Polymerase eta
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 8 of 9 Tina M. Albertson, University of Washington, USA Polymerase Delta and Epsilon Proofreading Act in Parallel Pathways to Suppress Spontaneous Mutation and Cancer in Mice
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: New Polymerases Room: Anasazi Ballroom Speaker 9 of 9 Garry Dallmann, Venria Bioscience, USA Identification of Small–Molecule Inhibitors of DNA Polymerase III Holoenzyme
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 1 of 9 * Richard A. Fishel, Ohio State University, USA
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 2 of 9 Guo-Min Li, University of Kentucky, USA Identification of a Novel Mismatch Repair Stimulating Factor involving RFX
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 3 of 9 Ling Xia, Molecular Medicine and Genetics, USA The Role of Mismatch Repair and Recombination in the Processing of DNA Alkylating Damage in Living Yeast Cells
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 4 of 9 Martin Kupiec, Tel Aviv University, Israel Elg1 is Required for Genome Stability
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 5 of 9 Renee D. Paulsen, Stanford University, USA siRNA Screening for Novel Regulators of Genomic Integrity
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 6 of 9 Kirstin Bass, Mount Sinai School of Medicine, USA Brc1: Coordinating DNA Repair and Replication
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 7 of 9 † Bernard S. Lopez, Institut Gustave Roussy, France PKBalpha/AKT1 Inhibits Homologous Recombination by Cytoplasmic Retention of BRCA1 and Rad51, Mediated by FOXO1a: Impact in Sporadic Breast Cancer
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 8 of 9 Mark A. Brenneman, Rutgers University, USA DSS1, a BRCA2-Associated Protein, Regulates Homologous Recombinational Repair in Human Cells
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Recombination and Repair in Higher Eukaryotes Room: Zia Ballroom Speaker 9 of 9 Sandra K. Weller, University of Connecticut School of Medicine, USA HSV-1 inactivates the ATR pathway during infection by sequestration of ATRIP
Wednesday, February 13 \| 4:30PM - 5:00PM Coffee Available Room: Pavillion
Wednesday, February 13 \| 5:00PM - 7:00PM Replication Response to Checkpoints Room: Anasazi Ballroom Speaker 1 of 3 * Stephen P. Bell, Massachusetts Institute of Technology, USA DDK Targets Mcm 2-7 Proteins in the Pre-RC
Wednesday, February 13 \| 5:00PM - 7:00PM Replication Response to Checkpoints Room: Anasazi Ballroom Speaker 2 of 3 Marco F. Foiani, Instituto FIRC di Oncologia Molecolare, Italy Pathways Controlling Replication Fork Stability
Wednesday, February 13 \| 5:00PM - 7:00PM Replication Response to Checkpoints Room: Anasazi Ballroom Speaker 3 of 3 Karlene A. Cimprich, Stanford University, USA Mechanisms for Maintaining Genome Stability at the Replication Fork
Wednesday, February 13 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Pavillion
Wednesday, February 13 \| 7:30PM - 10:00PM Poster Session 3 Room: Pavillion
Thursday, February 14 \| 7:00AM - 8:00AM Breakfast Room: Eldorado Court
Thursday, February 14 \| 8:00AM - 11:00AM Genome Stability and DNA Repair, Alternative Polymerases, DS B Repair Room: Anasazi Ballroom Speaker 1 of 4 * Richard D. Kolodner, Ludwig Institute for Cancer Research, USA Identification of Pathways that Prevent Genome Instability
Thursday, February 14 \| 8:00AM - 11:00AM Genome Stability and DNA Repair, Alternative Polymerases, DS B Repair Room: Anasazi Ballroom Speaker 2 of 4 Lorena S. Beese, Duke University Medical Center, USA Human mutS alpha DNA Lesion Recognition Complex
Thursday, February 14 \| 8:00AM - 11:00AM Genome Stability and DNA Repair, Alternative Polymerases, DS B Repair Room: Anasazi Ballroom Speaker 3 of 4 Roger Woodgate, National Institutes of Health, USA Y-Family Polymerases and Their Role in the Translesion Synthesis of Alkylation Damage
Thursday, February 14 \| 8:00AM - 11:00AM Genome Stability and DNA Repair, Alternative Polymerases, DS B Repair Room: Anasazi Ballroom Speaker 4 of 4 Jan Karlseder, The Salk Institute for Biological Studies, USA C. elegans Telomeres Contain both G-Strand and C-Strand Overhangs that are Bound by Distinct Telomere-Binding Proteins
Thursday, February 14 \| 9:20AM - 9:40AM Coffee Break Room: Pavillion
Thursday, February 14 \| 11:00AM - 11:00AM On Own for Lunch
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 1 of 8 * Xiaojiang S. Chen, University of Southern California, USA The Hexameric Structure of a DnaB-Family Replicative Helicase and its Functional Interplay with Primase
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 2 of 8 Sharmistha Ghosh, Harvard Medical School, USA Escherichia Coli Thioredoxin Interacts wiht the Thioredoxin Binding Domain of Bacteriophage T7 DNA Polymerase and with Helicase/Primase at the Replication Fork
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 3 of 8 Iben Bach Bentsen, Aarhus University, Denmark Identification of Protein Factors Required during Stalled Replication at a Protein-DNA Barrier
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 4 of 8 Hong Yan, Fox Chase Cancer Center, USA Biochemical Analysis of Replication Fork Stall and Restart at a Defined Lesion in Xenopus Nucleoplasmic Extracts
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 5 of 8 Chiara Indiani, Rockefeller University, USA Programmed Slowing of the Replication Fork in Response to DNA Damage
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 6 of 8 Kieran Emptage, University of Newcastle, UK Archaeal Family B DNA Polymerase Stalling, Protection and Interaction with PCNA at Deaminated Bases
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 7 of 8 Yu-Hao Paul Chang, University of Southern California, USA Crystal Structure of the GINS Complex and Functional Insights into its Role in DNA Replication
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 7: Fork Stalling And Structure of Fork Complexes Room: Anasazi Ballroom Speaker 8 of 8 Roxana Georgescu, Rockefeller University, USA Structure of a Sliding Clamp on DNA
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 1 of 8 * Ronald Chalmers, University of Nottingham Medical School, UK Base-Flipping Dynamics in V(D)J Recombination
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 2 of 8 Michael G. Chandler, CNRS UMR 5100, France Transposition of the Novel Insertion Sequence IS608: Biochemistry and Assimilation into the Cell Cycle
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 3 of 8 Hiroshi Nakai, Georgetown University Medical Center, USA Effect of Translation Factor IF2-2 at the Interface of Recombination and Replication for Bacteriophage MU Transposition
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 4 of 8 Patrick C. Swanson, Creighton University, USA Evidence for Long Range RAG1/2 Interactions with Coding Sequences in Discrete V(D)J Initiation Complexes Assembled on Coupled Cleavage Substrates
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 5 of 8 Adam G. W. Matthews, Massachusetts Institute of Technology, USA RAG2 PHD Finger Couples Histone H3 Lysine 4 Trimethylation with V(D)J Recombination
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 6 of 8 Lisa Postow, Rockefeller University, USA Ubiquitin-Mediated Removal of Ku80 from DNA Breaks
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 7 of 8 John R. Lydeard, Biogen Idec, USA Break-Induced Replication Requires both the Leading and Lagging Strand Replication Machinery
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 8: VDJ, End Joining and Transposition Room: Zia Ballroom Speaker 8 of 8 Jennifer A. Cobb, University of Calgary, Canada The Mre11 Complex and S Phase: Maintaining the Replisome during Fork Stalling
Thursday, February 14 \| 4:30PM - 5:00PM Coffee Available Room: Pavillion
Thursday, February 14 \| 5:00PM - 7:00PM Replication Stalling and Restart Room: Anasazi Ballroom Speaker 1 of 3 * Kenneth J. Marians, Memorial Sloan Kettering Cancer Center, USA Mechanisms of Replication Fork Reactivation
Thursday, February 14 \| 5:00PM - 7:00PM Replication Stalling and Restart Room: Anasazi Ballroom Speaker 2 of 3 Karim Labib, University of Dundee, UK Regulating the Progression of Eukaryotic DNA Replication Forks
Thursday, February 14 \| 5:00PM - 7:00PM Replication Stalling and Restart Room: Anasazi Ballroom Speaker 3 of 3 James E. Haber, Brandeis University, USA Break Induced-Replication and the Recombination Execution Checkpoint
Thursday, February 14 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Pavillion
Thursday, February 14 \| 8:00PM - 11:00PM Entertainment Room: Pavillion
Thursday, February 14 \| 8:00PM - 11:00PM Cash Bar Room: Pavillion
Friday, February 15 \| 10:25AM - 10:25AM Departure *Session Chair.