Web Desc
NF-kappaB
Organizer(s): Vishva M. Dixit, Shao-Cong Sun and Sankar Ghosh
Date: February 12 - 17, 2008
Location: Fairmont Banff Springs, Banff, AB, Canada
Supported by the Director's Fund
Summary of Meeting:
Research focused on NF-kappaB has continued to grow exponentially in recent years, fueled in part by the progress in accruing basic knowledge on this pathway, which in turn has provided the stimulus for applied research. Continued growth in this field is also the result of discoveries that reveal the ever-increasing importance of NF-kappaB in many cell types in both normal health and disease. NF-kappaB has become an integral part of diverse research disciplines, including immunology, signal transduction, chromatin regulation, autoimmune diseases, diabetes, osteoporosis and cancer, just to name a few. NF-kappaB is of great interest to clinical research and remains a prime target for therapeutic intervention in many diseases. The 2008 Keystone meeting on NF-kappaB will come at a particularly exciting time, when a number of unexpected new regulatory pathways and functions of this transcription factor family are emerging. For example extensive regulation of NF-kappaB at the chromatin level occurs in addition to the primary regulation, which is relief of inhibition by IkappaB proteins that normally keep NF-kappaB inactive in the cytoplasm. Regulation at the chromatin level is accomplished via signal-induced modifications of NF-kappaB itself or of interacting partners. An additional area of great activity has been the discovery of regulatory ubiquitination events in multiple steps of the NF-kappaB pathway, and we anticipate that the meeting will provide significant new insight in this area. In recent years evidence for the importance and extent of inappropriate activation of NF-kappaB in tumorigenesis has continued to emerge. The link between inflammation (via NF-kappaB) and tumorigenesis has led to tremendous interest in this area and we anticipate that significant new information will be presented at this meeting. New data will be presented on the roles of NF-kappaB in multiple myeloma, squamous head and neck cancers, breast cancer and diffuse large B cell lymphomas. Clinical trials are underway to evaluate NF-kappaB as a therapeutic target in these and other malignancies, and results from such trials are expected at this meeting.
Scholarship Deadline: October 12 2007
Discounted Abstract Deadline: October 12 2007
Abstract Deadline: November 12 2007
Discounted Registration Deadline: December 12 2007
We gratefully acknowledge additional support for this conference from:

GlaxoSmithKline Research & Development, Ltd.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI077107-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, February 12 | 3:00PM - 7:30PM
Registration
Room: Van Horne Ballroom Foyer


Tuesday, February 12 | 6:30PM - 7:30PM
Refreshments
Room: Van Horne Ballroom Foyer


Tuesday, February 12 | 7:30PM - 8:30PM
Keynote Address
Room: Van Horne Ballroom Foyer AB

Speaker 1 of 1
Jules A. Hoffmann, Institute of Cellular and Molecular Biology, France
NF-kappaB: A Phylogenetic Perspective


Wednesday, February 13 | 7:00AM - 8:00AM
Breakfast
Room: New Brunswick, Alberta


Wednesday, February 13 | 8:00AM - 11:00AM
Regulation of the NF-kappaB Pathway
Room: Van Horne Ballroom AB

Speaker 1 of 5
Alain Israël, Institut Pasteur, France
Structure-Function Analysis of NEMO

Wednesday, February 13 | 8:00AM - 11:00AM
Regulation of the NF-kappaB Pathway
Room: Van Horne Ballroom AB

Speaker 2 of 5
Inder M. Verma, The Salk Institute, USA
Novel Roles of the IKK Complex

Wednesday, February 13 | 8:00AM - 11:00AM
Regulation of the NF-kappaB Pathway
Room: Van Horne Ballroom AB

Speaker 3 of 5
* Sankar Ghosh, Columbia University, USA
PDK1 Integrates CD28+ CD3 Signaling to NFkB

Wednesday, February 13 | 8:00AM - 11:00AM
Regulation of the NF-kappaB Pathway
Room: Van Horne Ballroom AB

Speaker 4 of 5
Shao-Cong Sun, University of Texas MD Anderson Cancer Center, USA
Negative Regulation of NF-kB by CYLD

Wednesday, February 13 | 8:00AM - 11:00AM
Regulation of the NF-kappaB Pathway
Room: Van Horne Ballroom AB

Speaker 5 of 5
Gutian Xiao, University of Pittsburgh Medical Center, USA
Short Talk: Novel Mechanisms of p100 Processing and NF-kappaB Regulation

Wednesday, February 13 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Ballroom Foyer


Wednesday, February 13 | 11:00AM - 1:00PM
Poster Setup
Room: New Brunswick, Alberta


Wednesday, February 13 | 11:00AM - 11:00AM
On Own for Lunch


Wednesday, February 13 | 1:00PM - 10:00PM
Poster Viewing
Room: New Brunswick, Alberta


Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 1 of 9
* Alexander Hoffmann, University of California, Los Angeles, USA

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 2 of 9
Olga V. Savinova, Sanford Research/University of South Dakota, USA
Molecular Organization of Endogenous p105 and p100 Complexes and their Role in LPS Signalling

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 3 of 9
Tom Huxford, San Diego State University, USA
IkappaBzeta Specifically Binds NF-kappaB p50 Homodimer and Forms a Ternary Complex on kappaB DNA

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 4 of 9
Ralf B. Marienfeld, University of Ulm, Germany
The Phosphorylation of Serine 68 in the IKK-Binding Domain of NEMO Interferes with the Structure of the IKK-Complex and the TNF-alpha-Induced NF-kappaB Activity

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 5 of 9
Melanie Herscovitch, Boston University, USA
Role of Cysteine Residues in NEMO Structure and Function

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 6 of 9
Sergei Makarov, Attagene, Inc., USA
Homogenous Reporter System Enables Quantitative Functional Assessment of Multiple Transcription Factors

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 7 of 9
Casey W. Wright, University of Texas Medical Branch, USA
ARNT Modulates CD30-Mediated NF-kappaB Transactivation Through Regulation of RelB

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 8 of 9
Kam C. Yeung, University of Toledo Health Science Campus, USA
RKIP is a Scaffold Protein of the IkappaB Kinase Complex

Wednesday, February 13 | 2:30PM - 4:30PM
Workshop 1: NF-kappaB Signaling
Room: Van Horne Ballroom AB

Speaker 9 of 9
Benjamin A.A. Barre, University of Bristol, UK
A Cell Cycle Regulatory Network Controlling NF-kappaB Subunit Activity and Function

Wednesday, February 13 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Ballroom Foyer


Wednesday, February 13 | 5:00PM - 7:00PM
Signaling to NF-kappaB
Room: Van Horne Ballroom AB

Speaker 1 of 4
* Vishva M. Dixit, Genentech, Inc., USA
Role of cIAP1/2 in the Non-Canonical NF-kB Survival Pathway

Wednesday, February 13 | 5:00PM - 7:00PM
Signaling to NF-kappaB
Room: Van Horne Ballroom AB

Speaker 2 of 4
Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA
Signaling by Ubiquitin and Viruses to NFkB

Wednesday, February 13 | 5:00PM - 7:00PM
Signaling to NF-kappaB
Room: Van Horne Ballroom AB

Speaker 3 of 4
Xin Lin, University of Texas MD Anderson Cancer Center, USA
NF-kappaB Signaling Regulated by CARMA Family Members

Wednesday, February 13 | 5:00PM - 7:00PM
Signaling to NF-kappaB
Room: Van Horne Ballroom AB

Speaker 4 of 4
Steven C. Ley, Francis Crick Institute, UK
Short Talk: NF-kappaB1 p105: A Third Way to NF-kappaB Activation

Wednesday, February 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: New Brunswick, Alberta


Wednesday, February 13 | 7:30PM - 10:00PM
Poster Session 1
Room: New Brunswick, Alberta


Thursday, February 14 | 7:00AM - 8:00AM
Breakfast
Room: New Brunswick, Alberta


Thursday, February 14 | 7:00AM - 8:00AM
Poster Setup
Room: New Brunswick, Alberta


Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 1 of 7
* Shao-Cong Sun, University of Texas MD Anderson Cancer Center, USA

Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 2 of 7
Gioacchino Natoli, Humanitas University, Italy
NF-kB Inflammation and the Epigenome: A Tale of Reciprocal Influences

Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 3 of 7
Warner Craig Greene, Gladstone Institute of Virology and Immunology, USA
New Insights into Molecular Underpinnings of HIV Latency

Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 4 of 7
Hao Wu, Harvard Medical School, Boston Children's Hospital, USA
Crystal Structure of TRAF6 Reveals the Molecular Mechanism for Poly-Ubiquitin Synthesis

Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 5 of 7
Stephen T. Smale, University of California, Los Angeles, USA
Differential Gene Activation by NF-kappaB Family Members in a Chromatin Environment

Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 6 of 7
Edward W. Harhaj, University of Miami School of Medicine, USA
Short Talk: TAX1BP1 and Itch are Essential Subunits of an A20 Ubiquitin Editing Complex

Thursday, February 14 | 8:00AM - 11:15AM
Regulation of NF-kappaB and Chromatin
Room: Van Horne Ballroom AB

Speaker 7 of 7
Neil D. Perkins, University of Newcastle, UK
Short Talk: Regulation of RelA(p65) Functionality

Thursday, February 14 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Ballroom Foyer


Thursday, February 14 | 11:15AM - 12:00PM
Lunch
Room: New Brunswick, Alberta


Thursday, February 14 | 12:00PM - 2:30PM
Poster Session 2
Room: New Brunswick, Alberta


Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 1 of 9
* Genhong Cheng, University of California, Los Angeles, USA

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 2 of 9
Adam S. Adler, GigaGen Inc., USA
Motif Module Map Reveals Enforcement of Aging by Continual NF-kappaB Activity

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 3 of 9
Jeremy S. Tilstra, University of Pittsburgh, USA
NF-kappaB Inhibitor, PTD-NBD, Delays the Onset of Age-Associated Functional Decline in a Model of Advanced Aging

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 4 of 9
Ruaidhrí John Carmody, University College Cork, Ireland
Bcl-3 Inhibits Inflammatory Gene Expression By Blocking NF-kappaB p50 Ubiquitination

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 5 of 9
Florian R. Greten, Institute for Tumor Biology and Experimental Therapy, Germany
NF-kappaB Activation in Enterocytes Regulates Survival and Sensitivity to Chemotherapy in a Model of Sporadic Intestinal Tumorigenesis

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 6 of 9
Bernd Baumann, University of Ulm, Germany
Constitutive IKK2 Activation in Acinar Cells is Sufficient to Induce Acute Pancreatitis in vivo

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 7 of 9
Michael Hinz, Max Delbrück Center for Molecular Medicine, Germany
Inhibition of Hsp90-Cdc37 Interferes with Signal-Responsiveness of IkappaB Kinases and Provides a Therapeutic Option for NF-kappaB Dependent Diseases

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 8 of 9
Deborah Veis Novack, Washington University, USA
The Alternative NF-kappaB Pathway via NIK and RelB Mediates Tumor-Induced Osteolysis

Thursday, February 14 | 2:30PM - 4:30PM
Workshop 2: NF-kappaB in Inflammatory Diseases and Cancer
Room: Van Horne Ballroom AB

Speaker 9 of 9
Diana Legarda-Addison, Mount Sinai School of Medicine, USA
NF-kappaB-Independent Role of NEMO/IKKgamma in Regulating TNF-Induced Apoptosis

Thursday, February 14 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Ballroom Foyer


Thursday, February 14 | 5:00PM - 7:00PM
Genetic Analysis of NF-kappaB Function
Room: Van Horne Ballroom AB

Speaker 1 of 4
Manolis Pasparakis, University of Cologne, Germany
Genetic Analysis of the IKK Complex Using Conditional Knock-Outs

Thursday, February 14 | 5:00PM - 7:00PM
Genetic Analysis of NF-kappaB Function
Room: Van Horne Ballroom AB

Speaker 2 of 4
Alexander Hoffmann, University of California, Los Angeles, USA
Homeostatic Mechanisms Determine the Responsiveness of the IkappaB-NF-kappaB Signaling Module

Thursday, February 14 | 5:00PM - 7:00PM
Genetic Analysis of NF-kappaB Function
Room: Van Horne Ballroom AB

Speaker 3 of 4
* Ranjan Sen, National Institute of Aging, National Institutes of Health, USA
Regulation of NF-kappaB Function in Lymphocytes

Thursday, February 14 | 5:00PM - 7:00PM
Genetic Analysis of NF-kappaB Function
Room: Van Horne Ballroom AB

Speaker 4 of 4
Shigeki Miyamoto, University of Wisconsin, Madison, USA
Short Talk: Multiple Developmental Defects in Mice Lacking the IkappaBalpha N-Terminal Nuclear Export Sequence

Thursday, February 14 | 7:00PM - 7:00PM
On Own for Dinner


Friday, February 15 | 7:00AM - 8:00AM
Breakfast
Room: New Brunswick, Alberta


Friday, February 15 | 8:00AM - 11:00AM
NF-kappaB Signaling in the Innate Immune System
Room: Van Horne Ballroom AB

Speaker 1 of 5
* Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Diversity in the NF-kappaB System Revealed by Analysis of Toll-Like Receptor Signaling Pathways


Friday, February 15 | 8:00AM - 11:00AM
NF-kappaB Signaling in the Innate Immune System
Room: Van Horne Ballroom AB

Speaker 2 of 5
Michelle A. Kelliher, University of Massachusetts Medical School, USA
Rip Proteins in Innate Immune Signaling

Friday, February 15 | 8:00AM - 11:00AM
NF-kappaB Signaling in the Innate Immune System
Room: Van Horne Ballroom AB

Speaker 3 of 5
Genhong Cheng, University of California, Los Angeles, USA
TRAF3, a Critical Negative Regulator of Both Classical and Alternative NF-kappaB Activation

Friday, February 15 | 8:00AM - 11:00AM
NF-kappaB Signaling in the Innate Immune System
Room: Van Horne Ballroom AB

Speaker 4 of 5
Michael Naumann, Institute of Experimental Internal Medicine, Germany
Short Talk: COP9 Signalosome Controls the Turnover of IkappaB-Molecules

Friday, February 15 | 8:00AM - 11:00AM
NF-kappaB Signaling in the Innate Immune System
Room: Van Horne Ballroom AB

Speaker 5 of 5
Martin E. Dorf, Harvard Medical School, USA
Short Talk: PKC Phosphorylation of TRAF2 Mediates Recruitment of IKKa/b and K63-linked Polyubiquitination

Friday, February 15 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Ballroom Foyer


Friday, February 15 | 11:00AM - 1:00PM
Poster Setup
Room: New Brunswick, Alberta


Friday, February 15 | 11:00AM - 11:00AM
On Own for Lunch


Friday, February 15 | 1:00PM - 10:00PM
Poster Viewing
Room: New Brunswick, Alberta


Friday, February 15 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Ballroom Foyer


Friday, February 15 | 5:00PM - 7:00PM
NF-kappaB and the Adaptive Immune System
Room: Van Horne Ballroom AB

Speaker 1 of 3
* Ulrich K. Siebenlist, NIAID, National Institutes of Health, USA
Regulation of NF-kappaB in Immunologic Contexts

Friday, February 15 | 5:00PM - 7:00PM
NF-kappaB and the Adaptive Immune System
Room: Van Horne Ballroom AB

Speaker 2 of 3
Steve D. Gerondakis, Monash University, Australia
Negative Regulation of CD8 Memory T-Cell Development and Homeostasis

Friday, February 15 | 5:00PM - 7:00PM
NF-kappaB and the Adaptive Immune System
Room: Van Horne Ballroom AB

Speaker 3 of 3
Daniel Krappmann, Helmholtz Zentrum München, Germany
Short Talk: Malt1 Ubiquitination Triggers NF-kappaB Signaling upon T cell Activation

Friday, February 15 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: New Brunswick, Alberta


Friday, February 15 | 7:30PM - 10:00PM
Poster Session 3
Room: New Brunswick, Alberta


Saturday, February 16 | 7:00AM - 8:00AM
Breakfast
Room: New Brunswick, Alberta


Saturday, February 16 | 8:00AM - 11:00AM
NF-kappaB, Inflammation and Cancer
Room: Van Horne Ballroom AB

Speaker 1 of 5
* Michael Karin, University of California, San Diego, USA
IKK-NF-kappaB Signaling and the Control of Caspase Activation and Cell Survival

Saturday, February 16 | 8:00AM - 11:00AM
NF-kappaB, Inflammation and Cancer
Room: Van Horne Ballroom AB

Speaker 2 of 5
Yinon M. Ben-Neriah, Hebrew University, Hadassah Medical School, Israel
The Role of NFkB in Liver Physiology and Cancer: Lessons from Different Animal Models

Saturday, February 16 | 8:00AM - 11:00AM
NF-kappaB, Inflammation and Cancer
Room: Van Horne Ballroom AB

Speaker 3 of 5
Louis M. Staudt, NCI, National Institutes of Health, USA
Genomic Aberrations that Activate NF-kappaB Constitutively in Lymphoid Malignancies

Saturday, February 16 | 8:00AM - 11:00AM
NF-kappaB, Inflammation and Cancer
Room: Van Horne Ballroom AB

Speaker 4 of 5
Thomas D. Gilmore, Boston University, USA
A Human Model System for Re1-Induced B-Cell Lymphomagenesis

Saturday, February 16 | 8:00AM - 11:00AM
NF-kappaB, Inflammation and Cancer
Room: Van Horne Ballroom AB

Speaker 5 of 5
Carter Van Waes, NIDCD, National Institutes of Health, USA
Short Talk: The NF-kappaB Proteome and Transcriptome as Biomarkers and Targets for Therapy in Human Head and Neck Squamous Cell Carcinomas

Saturday, February 16 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Ballroom Foyer


Saturday, February 16 | 11:00AM - 11:00AM
On Own for Lunch


Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 1 of 9
* Ulrich K. Siebenlist, NIAID, National Institutes of Health, USA

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 2 of 9
Michael J. May, University of Pennsylvania, USA
The IKK Complex Recruits Homer-3 to the Immunological Synapse

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 3 of 9
Fabrice Agou, Institut Pasteur, France
Solution Structure of NEMO Zinc Finger and Impact of an Anhidrotic Ectodermal Dysplasia with Immunodeficiency-Related Point Mutation


Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 4 of 9
Christian Kaltschmidt, Bielefeld University, Germany
NF-kappaB is Transported to the Nucleus via Cytoplasmic Dynein/Dynactin Motor Complexes in Hippocampal Neurons

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 5 of 9
Raquel Sitcheran, Texas A&M Health Science Center, USA
Glutamate Signalling to NFkB Glial Cells of the CNS

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 6 of 9
Lin-Feng Chen, University of Illinois at Urbana-Champaign, USA
Brd4 Coactivates NF-kappaB-mediated Inflammatory Response via Specific Binding to Acetylated RelA

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 7 of 9
Ilaria Tassi, Alector, USA
Dendritic Cells Require PLCgamma2 to Sense Pathogen Associated Molecular Patterns through TLR and Non-TLR Receptors

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 8 of 9
Miguel E. Moreno-Garcia, Seattle Children's Research Institute, USA
CARMA1 Nucleates Activation-Induced Degradation of the CARMA/Bcl10/Malt Signalosome to Limit NF-kappaB Activation in Lymphocytes

Saturday, February 16 | 2:30PM - 4:30PM
Workshop 3: NF-kappaB in the Immune Response
Room: Van Horne Ballroom AB

Speaker 9 of 9
Nadine Hövelmeyer, University of Mainz, Germany
Regulation of B Cell Homeostasis and Activation by the Tumor Suppressor Gene Cyld

Saturday, February 16 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Ballroom Foyer


Saturday, February 16 | 5:00PM - 7:00PM
NF-kappaB: Benchside to Clinic
Room: Van Horne Ballroom AB

Speaker 1 of 3
Anning Lin, Shanghai Institute of Biochemistry and Cell Biology, China
Wiring the Intracellular Signaling Circuitry by NF-kappaB

Saturday, February 16 | 5:00PM - 7:00PM
NF-kappaB: Benchside to Clinic
Room: Van Horne Ballroom AB

Speaker 2 of 3
Rudi Beyaert, Ghent University - VIB, Belgium
Short Talk: ABINs and TAX1BP1 are Ubiquitin-Binding Proteins that Negatively Regulate NF-kappaB Activation by Targeting A20 to Specific Signaling Proteins

Saturday, February 16 | 5:00PM - 7:00PM
NF-kappaB: Benchside to Clinic
Room: Van Horne Ballroom AB

Speaker 3 of 3
* Albert S. Baldwin Jr., University of North Carolina School of Medicine, USA
Targeting NF-kappaB Activity in Cancer Cells

Saturday, February 16 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: New Brunswick, Alberta


Saturday, February 16 | 8:00PM - 11:00PM
Entertainment
Room: New Brunswick, Alberta


Saturday, February 16 | 8:00PM - 11:00PM
Cash Bar
Room: New Brunswick, Alberta


Sunday, February 17 | 10:25AM - 10:25AM
Departure


*Session Chair.