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This meeting took place in the past. Here is a list of meetings that are related:
Chromatin Dynamics (2012J4)
Epigenomics (2012J3)
Environmental Epigenomics and Disease Susceptibility (2011D3)
Histone Code: Fact or Fiction? (2011A6)
Molecular Basis for Chromatin Structure and Regulation (2010A8)
Chromatin Dynamics and Higher Order Organization (2009C4)
Epigenetics, Development and Human Disease (2009A1)
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Web Desc
Molecular Basis for Chromatin Modifications and Epigenetic Phenomena
Organizer(s): Peter Fraser, Sepideh Khorasanizadeh and Asifa Akhtar
Date: April 07 - 12, 2008
Location: Snowmass Resort, Snowmass, CO, USA
Supported by the Director's Fund
Summary of Meeting:
Many chromatin modifications and structures are surprisingly dynamic, yet are involved in initiating and heritably maintaining distinct gene expression patterns that direct and preserve cellular identities. The molecules that target and regulate these modifications and how they influence—and may be influenced by—higher-order chromatin structures, nuclear organization, and various nuclear processes, are areas of intense interest and excitement. This meeting will examine the latest discoveries surrounding the molecular basis of chromatin modifications and explore their connections to various biological processes and epigenetic phenomena such as dosage compensation, imprinting, heterochromatin formation and gene expression in differentiation, development and disease. The goal is to promote a more integrated picture of the molecular interrelationships between chromatin structure and function that exercise the hidden regulatory information in the genomes of complex organisms.
Scholarship Deadline: December 7 2007
Discounted Abstract Deadline: December 7 2007
Abstract Deadline: January 10 2008
Discounted Registration Deadline: February 7 2008
We gratefully acknowledge additional support for this conference from:
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
Program
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Monday, April 07
| 3:00PM - 7:30PM
Registration
Room: 1st Floor Foyer
Monday, April 07
| 6:30PM - 7:30PM
Refreshments
Room: 1st Floor Foyer
Monday, April 07
| 7:30PM - 8:30PM
Keynote Address
Room: Anderson Room
Speaker 1 of 2
*
Peter Fraser
, Florida State University, USA
Introduction
Monday, April 07
| 7:30PM - 8:30PM
Keynote Address
Room: Anderson Room
Speaker 2 of 2
Susan M. Gasser
, Friedrich Miescher Institute for Biomedical Research, Switzerland
INO80 Chromatin Remodeling Complex at Breaks, Forks and Promoters: A Multitude of Functions
Tuesday, April 08
| 7:00AM - 8:00AM
Breakfast
Room: Hoaglund/Erickson/ Carrol/Sinclair
Tuesday, April 08
| 8:00AM - 11:15AM
Post-Translational Modifications of Histones
Room: Anderson Room
Speaker 1 of 6
* Asifa Akhtar
, Max Planck Institute of Immunobiology and Epigenetics, Germany
Tuesday, April 08
| 8:00AM - 11:15AM
Post-Translational Modifications of Histones
Room: Anderson Room
Speaker 2 of 6
Yi Zhang
, HHMI/Harvard Medical School, Children's Hospital Boston, USA
Role of Histone Methylation in Germ Cell Development and Stem Cell Pluripotency
Tuesday, April 08
| 8:00AM - 11:15AM
Post-Translational Modifications of Histones
Room: Anderson Room
Speaker 3 of 6
Kristian Helin
, University of Copenhagen and Memorial Sloan Kettering Cancer Center, Denmark
Epigenetic Control and the Development of Cancer
Tuesday, April 08
| 8:00AM - 11:15AM
Post-Translational Modifications of Histones
Room: Anderson Room
Speaker 4 of 6
Zhibin Wang
, Johns Hopkins Bloomberg School of Public Health, USA
Short Talk: Combinatorial Patterns of Histone Acetylations and Methylations in the Human Genome
Tuesday, April 08
| 8:00AM - 11:15AM
Post-Translational Modifications of Histones
Room: Anderson Room
Speaker 5 of 6
Craig L. Peterson
, University of Massachusetts Medical School, USA
Histone Modifications and Chromatin Structure
Tuesday, April 08
| 8:00AM - 11:15AM
Post-Translational Modifications of Histones
Room: Anderson Room
Speaker 6 of 6
Laurie A. Boyer
, Massachusetts Institute of Technology, USA
Short Talk: H2AZ is Enriched at Polycomb Group Protein Target Regions in ES Cells and is Required for Proper Execution of Developmental Programs
Tuesday, April 08
| 9:20AM - 9:40AM
Coffee Break
Room: Hoaglund/Erickson/ Carrol/Sinclair
Tuesday, April 08
| 11:00AM - 1:00PM
Poster Setup
Room: Hoaglund/Erickson/ Carrol/Sinclair
Tuesday, April 08
| 11:00AM - 11:00AM
On Own for Lunch
Tuesday, April 08
| 1:00PM - 10:00PM
Poster Viewing
Room: Hoaglund/Erickson/ Carrol/Sinclair
Tuesday, April 08
| 4:30PM - 5:00PM
Coffee Available
Room: Hoaglund/Erickson/ Carrol/Sinclair
Tuesday, April 08
| 5:00PM - 7:00PM
Atomic Structures of Chromatin Protein Complexes
Room: Anderson Room
Speaker 1 of 5
Vidya Subramanian
, Massachusetts Institute of Technology, USA
Histone Chaperones: Structure, Function, and Regulation
Tuesday, April 08
| 5:00PM - 7:00PM
Atomic Structures of Chromatin Protein Complexes
Room: Anderson Room
Speaker 2 of 5
Masami Horikoshi
, University of Tokyo, Japan
Short Talk: From Histone Modification to Nuclesome Disassembly
Tuesday, April 08
| 5:00PM - 7:00PM
Atomic Structures of Chromatin Protein Complexes
Room: Anderson Room
Speaker 3 of 5
Ji-Joon Song
, Korea Advanced Institute of Science and Technology, South Korea
Short Talk: Structural Basis of Histone H4 Recognition by p55
Tuesday, April 08
| 5:00PM - 7:00PM
Atomic Structures of Chromatin Protein Complexes
Room: Anderson Room
Speaker 4 of 5
*
Sepideh Khorasanizadeh
, Sanford Burnham Prebys Medical Discovery Institute, USA
Multiple Roles for Chromodomains in Epigenetic Regulation
Tuesday, April 08
| 5:00PM - 7:00PM
Atomic Structures of Chromatin Protein Complexes
Room: Anderson Room
Speaker 5 of 5
Natalie Nady
, Pfizer, USA
Short Talk: Reading the Histone Code by MBT Domains – Structural Insights into MEthyl Mark Recognition
Tuesday, April 08
| 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Hoaglund/Erickson/ Carrol/Sinclair
Tuesday, April 08
| 7:30PM - 10:00PM
Poster Session 1
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 7:00AM - 8:00AM
Breakfast
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 1 of 7
*
Steven Henikoff
, Fred Hutchinson Cancer Research Center, USA
Histone Replacement Dynamics
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 2 of 7
Robert A. Martienssen
, Cold Spring Harbor Laboratory, USA
Slicing, Spreading and Copying Heterochromatin with RNAi
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 3 of 7
Sevinc Ercan
, University of North Carolina, USA
Short Talk: Dynamic and Bimodal Binding of the C. elegans Dosage Compensation Complex
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 4 of 7
Andrea Schäfer
, German Cancer Research Center, Germany
Short Talk: Molecular Mechanism of Active DNA Demethylation
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 5 of 7
Jessica K. Tyler
, Weill Cornell Medicine, USA
Chaperoning Histones
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 6 of 7
Jonathan Widom
, Northwestern University, USA
The Genomic Code for Nucleosome Positioning
Wednesday, April 09
| 8:00AM - 11:15AM
Chromatin Dynamics
Room: Anderson Room
Speaker 7 of 7
Raul A. Urrutia
, Mayo Clinic Rochester, USA
Subcodes within the Histone Code
Wednesday, April 09
| 9:20AM - 9:40AM
Coffee Break
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 11:15AM - 1:00PM
Poster Setup
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 11:15AM - 11:15AM
On Own for Lunch
Wednesday, April 09
| 1:00PM - 10:00PM
Poster Viewing
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 4:30PM - 5:00PM
Coffee Available
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 5:00PM - 7:00PM
Stem Cell Chromatin Dynamics
Room: Anderson Room
Speaker 1 of 6
* Wolf Reik
, Babraham Institute, UK
Wednesday, April 09
| 5:00PM - 7:00PM
Stem Cell Chromatin Dynamics
Room: Anderson Room
Speaker 2 of 6
Maarten Van Lohuizen
, Netherlands Cancer Institute, Netherlands
Polycomb Repressors Controlling Stem Cell Fate: Implications for Cancer and Development
Wednesday, April 09
| 5:00PM - 7:00PM
Stem Cell Chromatin Dynamics
Room: Anderson Room
Speaker 3 of 6
Bradley E. Bernstein
, Massachusetts General Hospital, USA
Chromatin Landscapes of Pluripotent and Lineage-Committed Cells
Wednesday, April 09
| 5:00PM - 7:00PM
Stem Cell Chromatin Dynamics
Room: Anderson Room
Speaker 4 of 6
Neil Brockdorff
, University of Oxford, UK
Chromatin Regulation by H2A Ubiquitylation
Wednesday, April 09
| 5:00PM - 7:00PM
Stem Cell Chromatin Dynamics
Room: Anderson Room
Speaker 5 of 6
Alexander Meissner
, Max Planck Institute for Molecular Genetics, Germany
Short Talk: Genome-scale DNA Methylation Maps of Pluripotent and Differentiated Cells
Wednesday, April 09
| 5:00PM - 7:00PM
Stem Cell Chromatin Dynamics
Room: Anderson Room
Speaker 6 of 6
Laurie A. Boyer
, Massachusetts Institute of Technology, USA
Short Talk: H2AZ is Enriched at Polycomb Group Protein Target Regions in ES Cells and is Required for Proper Execution of Developmental Programs
Wednesday, April 09
| 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Hoaglund/Erickson/ Carrol/Sinclair
Wednesday, April 09
| 7:30PM - 10:00PM
Poster Session 2
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 7:00AM - 8:00AM
Breakfast
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 7:00AM - 8:00AM
Poster Setup
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 1 of 7
* Craig L. Peterson
, University of Massachusetts Medical School, USA
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 2 of 7
Shiv I. S. Grewal
, NCI, National Institutes of Health, USA
Epigenetic Genome Control by RNAi and Transposon-Derived Proteins
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 3 of 7
Francis Stewart
, Technische Universitaet Dresden, Germany
The Histone Methyltransferase, Mll2, is only Essential in a Brief Window during Development and for the Germ Lineage
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 4 of 7
Rebecca A. Mosher
, University of Arizona, USA
Short Talk: PolIVb Influences RNA-Directed DNA Methylation and Demethylation Independently of its Role in siRNA Biogenesis
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 5 of 7
Jürg Müller
, Max Planck Institute of Biochemistry, Germany
Transcriptional Control by the Polycomb System
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 6 of 7
Kai Ge
, NIDDK, National Institutes of Health, USA
Isolation of Histone H3K4 Methyltransferase Complexes that Associate with a Histone H3K27 Demethylase
Thursday, April 10
| 8:00AM - 11:15AM
Epigenetics and Chromatin Modification Mechanisms
Room: Anderson Room
Speaker 7 of 7
Matthew Gamble
, Albert Einstein College of Medicine, USA
Short Talk: The Histone Variant MacroH2A1 Occupies Large Chromatin Domains and Positively Regulates Genes on Autosomes
Thursday, April 10
| 9:20AM - 9:40AM
Coffee Break
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 11:15AM - 12:15PM
Lunch
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 12:00PM - 2:30PM
Poster Session 3
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 1 of 7
* Janine Arts
, Ortho Biotech Oncology Research and Development (J&J), Belgium
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 2 of 7
Scott A. Armstrong
, Dana-Farber Cancer Institute, USA
H3K79 Methylation Abnormalities Define Murine and Human MLL-AF4 Leukemias
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 3 of 7
Tuncay Baubec
, Friedrich Miescher Institute, Switzerland
Zebularine is a Potent Inhibitor of Plant DNA Methylation
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 4 of 7
Donghang Cheng
, MD Anderson Cancer Center, USA
Arginine Methyltransferases as Novel Theraputic Targets for Breast Cancer
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 5 of 7
Vibhor Gupta
, Jawaharlal Nehru University, India
Profiling the Epigenetic and Transcriptional Effects of Histone Deacetylase Inhibitors
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 6 of 7
Joan Oliva Vilana
, LA Biomed, USA
Spontanous Formation of Tumors in Drug Primed DDC Mice: An Epigenetic Phenomena
Thursday, April 10
| 2:30PM - 4:30PM
Workshop: Chromatin as a Drug Target
Room: Anderson Room
Speaker 7 of 7
Pedro Vladimir Pena
, University of Colorado Health Sciences Center, USA
Molecular Mechanism of Histone H3K4Me3 Recognition by Plant Homeodomain of ING1 and the Effects of Cancer Specific Mutations
Thursday, April 10
| 4:30PM - 5:00PM
Coffee Available
Room: Hoaglund/Erickson/ Carrol/Sinclair
Thursday, April 10
| 5:00PM - 7:00PM
Large Scale Epigenetic Control
Room: Anderson Room
Speaker 1 of 5
* Anne C. Ferguson-Smith
, University of Cambridge, UK
Thursday, April 10
| 5:00PM - 7:00PM
Large Scale Epigenetic Control
Room: Anderson Room
Speaker 2 of 5
Asifa Akhtar
, Max Planck Institute of Immunobiology and Epigenetics, Germany
Dosage Compensation and Chromatin Regulation
Thursday, April 10
| 5:00PM - 7:00PM
Large Scale Epigenetic Control
Room: Anderson Room
Speaker 3 of 5
Edith Heard
, European Molecular Biology Laboratory, Germany
Nuclear and Chromatin Dynamics during X-Chromosome Inactivation
Thursday, April 10
| 5:00PM - 7:00PM
Large Scale Epigenetic Control
Room: Anderson Room
Speaker 4 of 5
Wolf Reik
, Babraham Institute, UK
Epigenetic Regulation of Lineage Commitment and Pluripotency in the Mammalian Embryo
Thursday, April 10
| 5:00PM - 7:00PM
Large Scale Epigenetic Control
Room: Anderson Room
Speaker 5 of 5
Mareike Puschendorf
, Friedrich Miescher Institute, Switzerland
Short Talk: PRC1 and Suv39h Specify Parental Asymmetry at Constitutive Heterochromatin in Early Mouse Embryos
Thursday, April 10
| 7:00PM - 7:00PM
On Own for Dinner
Friday, April 11
| 7:00AM - 8:00AM
Breakfast
Room: Hoaglund/Erickson/ Carrol/Sinclair
Friday, April 11
| 8:00AM - 11:00AM
Nuclear and Chromosome Dynamics
Room: Anderson Room
Speaker 1 of 6
*
Edith Heard
, European Molecular Biology Laboratory, Germany
Friday, April 11
| 8:00AM - 11:00AM
Nuclear and Chromosome Dynamics
Room: Anderson Room
Speaker 2 of 6
Peter Fraser
, Florida State University, USA
3D Transcription Networks
Friday, April 11
| 8:00AM - 11:00AM
Nuclear and Chromosome Dynamics
Room: Anderson Room
Speaker 3 of 6
Yijun Ruan
, The Jackson Laboratory for Genomic Medicine, USA
A Whole Genome View of Long-Range Chromatin Interactions in Transcription Regulation
Friday, April 11
| 8:00AM - 11:00AM
Nuclear and Chromosome Dynamics
Room: Anderson Room
Speaker 4 of 6
Michael R. Hübner
, Cold Spring Harbor Laboratory, USA
Short Talk: Dynamic Analysis and Induction of Polycomb Bodies at a Specific Genetic Locus
Friday, April 11
| 8:00AM - 11:00AM
Nuclear and Chromosome Dynamics
Room: Anderson Room
Speaker 5 of 6
Vicki L. Chandler
, Minerva Schools at Keck Graduate Institute, USA
Interchromosomal Transfer of Epigenetic Information
Friday, April 11
| 8:00AM - 11:00AM
Nuclear and Chromosome Dynamics
Room: Anderson Room
Speaker 6 of 6
Anton Krumm
, University of Washington Medical Center, USA
Short Talk: Role of Cohesion in Interphase Chromatin
Friday, April 11
| 9:20AM - 9:40AM
Coffee Break
Room: Hoaglund/Erickson/ Carrol/Sinclair
Friday, April 11
| 11:00AM - 11:00AM
On Own for Lunch
Friday, April 11
| 4:30PM - 5:00PM
Coffee Available
Room: Hoaglund/Erickson/ Carrol/Sinclair
Friday, April 11
| 5:00PM - 7:00PM
Epigenomics and Disease
Room: Anderson Room
Speaker 1 of 5
*
Peter Fraser
, Florida State University, USA
Friday, April 11
| 5:00PM - 7:00PM
Epigenomics and Disease
Room: Anderson Room
Speaker 2 of 5
Robert J. Sims
, Constellation Pharmaceuticals, USA
Mechanisms of Epigenetic Signaling
Friday, April 11
| 5:00PM - 7:00PM
Epigenomics and Disease
Room: Anderson Room
Speaker 3 of 5
Janine Arts
, Ortho Biotech Oncology Research and Development (J&J), Belgium
Chromatin as a Drug Target
Friday, April 11
| 5:00PM - 7:00PM
Epigenomics and Disease
Room: Anderson Room
Speaker 4 of 5
Anne C. Ferguson-Smith
, University of Cambridge, UK
The Establishment and Maintenance of Genomic Methylation Imprints
Friday, April 11
| 5:00PM - 7:00PM
Epigenomics and Disease
Room: Anderson Room
Speaker 5 of 5
Nathan R. Rose
, University of Oxford, UK
Short Talk: Structural and Mechanistic Studies on the JMJD2 Histone Demethylases
Friday, April 11
| 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Hoaglund/Erickson/ Carrol/Sinclair
Friday, April 11
| 8:00PM - 11:00PM
Entertainment
Room: Hoaglund/Erickson/ Carrol/ Sinclair
Friday, April 11
| 8:00PM - 11:00PM
Cash Bar
Room: Hoaglund/Erickson/ Carrol/ Sinclair
Saturday, April 12
| 10:25AM - 10:25AM
Departure
*Session Chair.
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