Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Mechanisms and Consequences of Invertebrate-Microbe Interactions (2014A7)
The Gut Microbiome: The Effector/Regulatory Immune Network (2013B3)
The Microbiome (2012Q8)
Microbial Communities as Drivers of Ecosystem Complexity (2011C8)

Web Desc
Molecular Evolution as a Driving Force in Infectious Diseases Organizer(s): Jeffery K. Taubenberger, Edward C. Holmes and Thomas S. Whittam Date: April 08 - 13, 2008 Location: Beaver Run Resort, Breckenridge, CO, USA Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation Summary of Meeting: Infectious diseases have been a key driving force in evolution, both of the hosts and the pathogens. The era of genomics has made it possible to evaluate both infectious agents and their hosts at the genomic level. The evolutionary dynamics of viruses, bacteria and parasites, in their adaptive evolution to changes in host response or adaptation to new hosts is enormously complex. The burden of infectious diseases on people and domestic animals is staggering. We are only now beginning to achieve an understanding of how infectious organisms cause disease and how the complex patterns of immune response generated by their infections mitigate it. By bringing together experts in the evolution of viruses, bacteria and parasites, plus those studying host adaptation and evolution of the immune response, we hope that this meeting will stimulate further interaction between widely disparate lines of investigation. Global Health Travel Award Deadline: November 12 2007 Scholarship Deadline: December 10 2007 Discounted Abstract Deadline: December 10 2007 Abstract Deadline: January 14 2008 Discounted Registration Deadline: February 11 2008 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI078558-01 National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 5U13AI60000-05 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Molecular Evolution as a Driving Force in Infectious Diseases

Organizer(s): Jeffery K. Taubenberger, Edward C. Holmes and Thomas S. Whittam

Date: April 08 - 13, 2008
Location: Beaver Run Resort, Breckenridge, CO, USA

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation

Summary of Meeting:

Infectious diseases have been a key driving force in evolution, both of the hosts and the pathogens. The era of genomics has made it possible to evaluate both infectious agents and their hosts at the genomic level. The evolutionary dynamics of viruses, bacteria and parasites, in their adaptive evolution to changes in host response or adaptation to new hosts is enormously complex. The burden of infectious diseases on people and domestic animals is staggering. We are only now beginning to achieve an understanding of how infectious organisms cause disease and how the complex patterns of immune response generated by their infections mitigate it. By bringing together experts in the evolution of viruses, bacteria and parasites, plus those studying host adaptation and evolution of the immune response, we hope that this meeting will stimulate further interaction between widely disparate lines of investigation.

Global Health Travel Award Deadline: November 12 2007

Scholarship Deadline: December 10 2007

Discounted Abstract Deadline: December 10 2007

Abstract Deadline: January 14 2008

Discounted Registration Deadline: February 11 2008

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI078558-01

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 5U13AI60000-05

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Tuesday, April 08 \| 3:00PM - 7:30PM Registration Room: Foyer
Tuesday, April 08 \| 6:30PM - 7:30PM Refreshments Room: Foyer
Tuesday, April 08 \| 7:30PM - 8:30PM Keynote Address Room: Peaks 4-5 Speaker 1 of 2 * Jeffery K. Taubenberger, NIAID, National Institutes of Health, USA
Tuesday, April 08 \| 7:30PM - 8:30PM Keynote Address Room: Peaks 4-5 Speaker 2 of 2 David J. Weatherall, University of Oxford, John Radcliffe Hospital, UK The Role of Genetic Variation in Susceptibility to Malaria in Human Evolution: Was Haldane Right?
Wednesday, April 09 \| 7:00AM - 8:00AM Breakfast Room: Peaks 1-4
Wednesday, April 09 \| 8:00AM - 11:15AM RNA Viruses I Room: Peak 5 Speaker 1 of 6 Jeffery K. Taubenberger, NIAID, National Institutes of Health, USA The Evolutionary Dynamics of Influenza A Viruses
Wednesday, April 09 \| 8:00AM - 11:15AM RNA Viruses I Room: Peak 5 Speaker 2 of 6 * Edward C. Holmes, University of Sydney, Australia The Molecular Evolution and Phylodynamics of Dengue Virus
Wednesday, April 09 \| 8:00AM - 11:15AM RNA Viruses I Room: Peak 5 Speaker 3 of 6 Oliver G. Pybus, University of Oxford, UK Integrating Evolutionary and Epidemiological Dynamics: HIV and the Hepatitis C Virus
Wednesday, April 09 \| 8:00AM - 11:15AM RNA Viruses I Room: Peak 5 Speaker 4 of 6 Paul A. Rota, Centers for Disease Control, USA Molecular Epidemiology of Measles and Mumps Viruses
Wednesday, April 09 \| 8:00AM - 11:15AM RNA Viruses I Room: Peak 5 Speaker 5 of 6 Philippe Lemey, Katholieke Universiteit Leuven, Belgium Short Talk: Tracing Virus Migration Using Bayesian Phylogeographic Inference
Wednesday, April 09 \| 8:00AM - 11:15AM RNA Viruses I Room: Peak 5 Speaker 6 of 6 Naomi Lynne Forrester, University of Texas Medical Branch, USA Short Talk: Use of Phylogenetic Analysis to Reveal the Evolution, Epidemiology and Origin of Rabbit Haemorrhagic Disease Virus
Wednesday, April 09 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Wednesday, April 09 \| 11:15AM - 1:00PM Poster Setup Room: Peaks 1-4
Wednesday, April 09 \| 11:15AM - 11:15AM On Own for Lunch
Wednesday, April 09 \| 1:00PM - 10:00PM Poster Viewing Room: Peaks 1-4
Wednesday, April 09 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Wednesday, April 09 \| 5:00PM - 7:00PM RNA Viruses II Room: Peak 5 Speaker 1 of 5 * Jeffery K. Taubenberger, NIAID, National Institutes of Health, USA
Wednesday, April 09 \| 5:00PM - 7:00PM RNA Viruses II Room: Peak 5 Speaker 2 of 5 Kathryn V. Holmes, University of Colorado School of Medicine, USA Coronaviruses and Host Adaptation
Wednesday, April 09 \| 5:00PM - 7:00PM RNA Viruses II Room: Peak 5 Speaker 3 of 5 Alan D.T. Barrett, University of Texas Medical Branch, USA Introduction of West Nile Virus into North America: Of Humans, Birds, Mosquitoes and Mice
Wednesday, April 09 \| 5:00PM - 7:00PM RNA Viruses II Room: Peak 5 Speaker 4 of 5 Michael G. Katze, University of Washington, USA Functional Genomics will Save the World from Killer Viruses (but it Better Happen Soon!)
Wednesday, April 09 \| 5:00PM - 7:00PM RNA Viruses II Room: Peak 5 Speaker 5 of 5 Chung-Chau Hon, University of Hong Kong, Hong Kong Short Talk: Evidence of the Recombinant Origin of a Bat SARS-like Coronavirus and its Implications on the Direct Ancestor of SARS Coronavirus
Wednesday, April 09 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Peaks 1-4
Wednesday, April 09 \| 7:30PM - 10:00PM Poster Session 1 Room: Peaks 1-4
Thursday, April 10 \| 7:00AM - 8:00AM Breakfast Room: Peaks 1-4
Thursday, April 10 \| 7:00AM - 8:00AM Poster Setup Room: Peaks 1-4
Thursday, April 10 \| 8:00AM - 11:15AM DNA Viruses Room: Peak 5 Speaker 1 of 5 Elliot J. Lefkowitz, University of Alabama at Birmingham, USA Gene Acquisition and Gene Loss as Controlling Events in Poxvirus Speciation and Pathogenesis
Thursday, April 10 \| 8:00AM - 11:15AM DNA Viruses Room: Peak 5 Speaker 2 of 5 * Colin R. Parrish, Cornell University, USA Variation and Evolution of Parvoviruses and the Controls of Host Ranges
Thursday, April 10 \| 8:00AM - 11:15AM DNA Viruses Room: Peak 5 Speaker 3 of 5 Thomas F. Schulz, Medizinische Hochschule Hannover, Germany Functional Diversification of a Terminal Membrane Protein during Rhadinoviral Evolution
Thursday, April 10 \| 8:00AM - 11:15AM DNA Viruses Room: Peak 5 Speaker 4 of 5 Mary R. Odom, University of Alabama, Birmingham, USA Short Talk: Poxvirus Gene Evolution: The Contribution of Gene Capture from the Host
Thursday, April 10 \| 8:00AM - 11:15AM DNA Viruses Room: Peak 5 Speaker 5 of 5 Edgar E. Sevilla-Reyes, Instituto Nacional de Enfermedades Respiratorias, Mexico Short Talk: The Dynamic Gene Content of Human Cytomegalovirus
Thursday, April 10 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Thursday, April 10 \| 11:15AM - 12:00PM Lunch Room: Peaks 1-4
Thursday, April 10 \| 12:00PM - 2:30PM Poster Session 2 Room: Peaks 1-4
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 1 of 9 * Edward C. Holmes, University of Sydney, Australia
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 2 of 9 Nels C. Elde, University of Utah, USA Adaptive Evolution of Protein Kinase R Defeats a Substrate Mimic Encoded by Poxviruses
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 3 of 9 Willem M. van Ballegooijen, National Institute of Public Health and the Environment, Netherlands DNA of Hepatitis B Virus Reveals Impact of Vaccination
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 4 of 9 Elodie Ghedin, New York University, USA Intra-Host Diversity and Evolutionary Dynamics of Influenza Virus
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 5 of 9 Ma Luo, University of Manitoba, Canada Rapid Selection for HLA alleles that Protect against HIV-1 Infection Correlates Significantly to the Declining Incidence of HIV-1 in an East African Sex Worker Population
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 6 of 9 Molly Ohainle, Fred Hutchinson Cancer Research Center, USA The Conserved Anti-Retroelemement Activity of APOBEC3H was Independently Lost Twice in Recent Human Evolution
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 7 of 9 Bouke C. de Jong, Institute of Tropical Medicine, Antwerp, Belgium Mycobacterium Africanum: First to Arrive in West Africa?
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 8 of 9 Joel O. Wertheim, University of Arizona, USA Dating the Origin of SIV from Sooty Mangabey using a Relaxed Molecular Clock
Thursday, April 10 \| 2:30PM - 4:30PM Workshop Room: Peaks 4-5 Speaker 9 of 9 Tsan Yuk (Tommy) Lam, University of Hong Kong, China Transmission Dynamics of Natural Reassortant H5N1 Influenza Viruses in Indonesia
Thursday, April 10 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Thursday, April 10 \| 5:00PM - 7:00PM Retroviruses Room: Peak 5 Speaker 1 of 4 Beatrice H. Hahn, University of Pennsylvania, USA Origins of HIV-1 and Adaptation to its Human Host
Thursday, April 10 \| 5:00PM - 7:00PM Retroviruses Room: Peak 5 Speaker 2 of 4 John V. Moran, University of Michigan Medical School, USA Studies of a Human Transposable Element
Thursday, April 10 \| 5:00PM - 7:00PM Retroviruses Room: Peak 5 Speaker 3 of 4 * Nathan D. Wolfe, University of California, Los Angeles, USA Cross-Species Transmission and Establishment of Novel Human Retroviruses
Thursday, April 10 \| 5:00PM - 7:00PM Retroviruses Room: Peak 5 Speaker 4 of 4 Christine L. Clouser, University of Minnesota, USA Short Talk: Exploiting the Mutation Rate of HIV
Thursday, April 10 \| 7:00PM - 7:00PM On Own for Dinner
Friday, April 11 \| 7:00AM - 8:00AM Breakfast Room: Peaks 1-4
Friday, April 11 \| 8:00AM - 11:00AM Bacteria I Room: Peak 5 Speaker 1 of 6 Eun Chung Park, NIAID, USA Short Talk
Friday, April 11 \| 8:00AM - 11:00AM Bacteria I Room: Peak 5 Speaker 2 of 6 David Alland, Rutgers University, New Jersey Medical School, USA Evaluating the Evolution of Drug Resistance in Mycobacterium Tuberculosis
Friday, April 11 \| 8:00AM - 11:00AM Bacteria I Room: Peak 5 Speaker 3 of 6 M. Cristina Gutiérrez Perez, Institut Pasteur, France Mycobacterium tuberculosis and other Mycobacteria: Rethinking Tuberculosis in the Light of Evolution
Friday, April 11 \| 8:00AM - 11:00AM Bacteria I Room: Peak 5 Speaker 4 of 6 * Bruce R. Levin, Emory University, USA The Evolution, Rate and Population Genetics of Recombination in Bacteria with a Particular Focus on Transformation: An Opinionated Rant
Friday, April 11 \| 8:00AM - 11:00AM Bacteria I Room: Peak 5 Speaker 5 of 6 Sébastien Gagneux, Swiss Tropical and Public Health Institute, Switzerland Short Talk: A Multilocus Sequence Analysis of Mycobacterium tuberculosis
Friday, April 11 \| 8:00AM - 11:00AM Bacteria I Room: Peak 5 Speaker 6 of 6 Anne M. Buboltz, Pennsylvania State University, USA Short Talk: Replacement of Adenylate Cyclase Toxin in a Prominent Lineage of Bordetella bronchiseptica
Friday, April 11 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Friday, April 11 \| 11:15AM - 1:00PM Poster Setup Room: Peaks 1-4
Friday, April 11 \| 11:15AM - 11:15AM On Own for Lunch
Friday, April 11 \| 1:00PM - 10:00PM Poster Viewing Room: Peaks 1-4
Friday, April 11 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Friday, April 11 \| 5:00PM - 7:00PM Bacteria II Room: Peak 5 Speaker 1 of 4 * James M. Musser, Methodist Hospital Research Institute, USA Evolution of Virulence in Group A Streptococcus, the Flesh-Eater
Friday, April 11 \| 5:00PM - 7:00PM Bacteria II Room: Peak 5 Speaker 2 of 4 Nancy A. Moran, University of Texas at Austin, USA The Evolutionary Genomics of Bacterial Symbionts in Insects
Friday, April 11 \| 5:00PM - 7:00PM Bacteria II Room: Peak 5 Speaker 3 of 4 Mark Achtman, University College Cork, Ireland Helicobacter pylori
Friday, April 11 \| 5:00PM - 7:00PM Bacteria II Room: Peak 5 Speaker 4 of 4 Martin Antonio, Medical Research Council Laboratories, Gambia Short Talk: Enhanced Invasiveness of ST618 Streptococcus pneumoniae Serotype 1 Clone from The Gambia, West Africa
Friday, April 11 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Peaks 1-4
Friday, April 11 \| 7:30PM - 10:00PM Poster Session 3 Room: Peaks 1-4
Saturday, April 12 \| 7:00AM - 8:00AM Breakfast Room: Peaks 1-4
Saturday, April 12 \| 8:00AM - 11:00AM Parasites and Host Evolution I Room: Peak 5 Speaker 1 of 5 Mark Achtman, University College Cork, Ireland Salmonela Thypi and Versinia Pestis
Saturday, April 12 \| 8:00AM - 11:00AM Parasites and Host Evolution I Room: Peak 5 Speaker 2 of 5 Wendy Gibson, University of Bristol, UK Evolution of the Pathogenic Trypanosomes
Saturday, April 12 \| 8:00AM - 11:00AM Parasites and Host Evolution I Room: Peak 5 Speaker 3 of 5 * Peter Parham, Stanford University, USA Host Evolution: Interactions between Polymorphic Human Receptors and Ligands that Influence Immune Defense and Reproduction
Saturday, April 12 \| 8:00AM - 11:00AM Parasites and Host Evolution I Room: Peak 5 Speaker 4 of 5 Peter Sarnow, Stanford University School of Medicine, USA Host Evolution: Evolution of microRNA miR-122 to Aid in Hepatitis C Virus Replication
Saturday, April 12 \| 8:00AM - 11:00AM Parasites and Host Evolution I Room: Peak 5 Speaker 5 of 5 Jenny Tan, Genome Institute of Singapore, Singapore Short Talk: Elevated Levels of Common Nonsynonymous Variants in the Human Macrophage Receptor Gene, EMR1, Result from Balancing Selection
Saturday, April 12 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Saturday, April 12 \| 11:00AM - 11:00AM On Own for Lunch
Saturday, April 12 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Saturday, April 12 \| 5:00PM - 7:00PM Parasites and Host Evolution II Room: Peak 5 Speaker 1 of 4 * Martin F. Flajnik, University of Maryland, USA Evolution of Adaptive Immunity
Saturday, April 12 \| 5:00PM - 7:00PM Parasites and Host Evolution II Room: Peak 5 Speaker 2 of 4 Richard Carter, University of Edinburgh, UK Plasmodium vivax: Where in the World has it Been?
Saturday, April 12 \| 5:00PM - 7:00PM Parasites and Host Evolution II Room: Peak 5 Speaker 3 of 4 Sunetra Gupta, University of Oxford, UK Transmission Dynamics and Evolution of the Influenza Virus
Saturday, April 12 \| 5:00PM - 7:00PM Parasites and Host Evolution II Room: Peak 5 Speaker 4 of 4 Sara L. Sawyer, University of Texas at Austin, USA Short Talk: Evolution of the Anti-Retroviral TRIM5 and Related Genes
Saturday, April 12 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Peaks 1-4
Saturday, April 12 \| 8:00PM - 11:00PM Entertainment Room: Peaks 1-4
Saturday, April 12 \| 8:00PM - 11:00PM Cash Bar Room: Peaks 1-4
Sunday, April 13 \| 10:25AM - 10:25AM Departure *Session Chair.