Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Frontiers of Structural Biology (2014Z2)
High-Throughput Structural Biology (2012J5)
Structural Genomics: Expanding the Horizons of Structural Biology (2010J2)

Web Desc
Structural Genomics and its Applications to Chemistry, Biology and Medicine joint with Frontiers of Structural Biology Organizer(s): Ian A. Wilson, Janet M. Thornton and Kurt Wüthrich Date: January 06 - 11, 2008 Location: Sheraton Steamboat Resort, Steamboat Springs, Colorado, USA Supported by the Director's Fund For important information on the coronavirus, please click here Summary of Meeting: Structural genomics has already significantly advanced high throughput (HT) technologies, including automation and robotics, for cloning, expression, purification and determination of protein structures by crystallography and NMR. These methodologies are now being applied to the field of proteomics to accelerate our understanding of the ever expanding protein universe (fold and function) as a result of the explosion in gene sequencing and to tackle challenging targets, such as membrane proteins, macromolecular complexes and eukaryotic targets. This meeting will focus on current approaches in structural genomics and on how structural genomics tools can be applied to topical problems in structural, molecular, cell and chemical biology not only within large consortia, but also for single investigator laboratories and smaller scale projects. In this way, the enormous complexity presented by even single proteomes – such as human, mouse, as well as human pathogens – can be tackled so as to significantly impact chemical, biological and biomedical research. Scholarship Deadline: September 11 2007 Discounted Abstract Deadline: September 11 2007 Abstract Deadline: October 15 2007 Discounted Registration Deadline: November 6 2007 We gratefully acknowledge additional support for this conference from: ISOTEC, a member of the Sigma-Aldrich Group We gratefully acknowledge the generous grant for this conference provided by: National Institute of General Medical Sciences (NIGMS) Grant No. 1R13GM081951-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Structural Genomics and its Applications to Chemistry, Biology and Medicine

joint with Frontiers of Structural Biology

Organizer(s): Ian A. Wilson, Janet M. Thornton and Kurt Wüthrich

Date: January 06 - 11, 2008
Location: Sheraton Steamboat Resort, Steamboat Springs, Colorado, USA

Supported by the Director's Fund

For important information on the coronavirus, please click here

Summary of Meeting:

Structural genomics has already significantly advanced high throughput (HT) technologies, including automation and robotics, for cloning, expression, purification and determination of protein structures by crystallography and NMR. These methodologies are now being applied to the field of proteomics to accelerate our understanding of the ever expanding protein universe (fold and function) as a result of the explosion in gene sequencing and to tackle challenging targets, such as membrane proteins, macromolecular complexes and eukaryotic targets. This meeting will focus on current approaches in structural genomics and on how structural genomics tools can be applied to topical problems in structural, molecular, cell and chemical biology not only within large consortia, but also for single investigator laboratories and smaller scale projects. In this way, the enormous complexity presented by even single proteomes – such as human, mouse, as well as human pathogens – can be tackled so as to significantly impact chemical, biological and biomedical research.

Scholarship Deadline: September 11 2007

Discounted Abstract Deadline: September 11 2007

Abstract Deadline: October 15 2007

Discounted Registration Deadline: November 6 2007

We gratefully acknowledge additional support for this conference from:

ISOTEC, a member of the Sigma-Aldrich Group

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of General Medical Sciences (NIGMS)
Grant No. 1R13GM081951-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, January 06 \| 3:00PM - 7:30PM Registration Room: Foyer
Sunday, January 06 \| 6:30PM - 7:30PM Refreshments Room: Foyer
Sunday, January 06 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 1 of 4 * Wolfgang P. Baumeister, Max Planck Institute of Biochemistry, Germany
Sunday, January 06 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 2 of 4 * Ian A. Wilson, The Scripps Research Institute, USA
Sunday, January 06 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 3 of 4 Michael G. Rossmann, Purdue University, USA Hybrid Structural Approaches: The Study of Viruses
Sunday, January 06 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 4 of 4 Jeffrey I. Gordon, Washington University School of Medicine, USA The Human Microbiome: Exploring the Microbial Side of Ourselves
Monday, January 07 \| 7:00AM - 8:00AM Breakfast Room: 3 Saddles/Bear River
Monday, January 07 \| 8:00AM - 11:15AM Advances in Protein Production and Crystallization Room: Sunshine Speaker 1 of 6 * Aled M. Edwards, University of Toronto, Canada
Monday, January 07 \| 8:00AM - 11:15AM Advances in Protein Production and Crystallization Room: Sunshine Speaker 2 of 6 Lance Stewart, Institute for Protein Design at University of Washington, USA Synthetic Gene Design for Structural Proteomics
Monday, January 07 \| 8:00AM - 11:15AM Advances in Protein Production and Crystallization Room: Sunshine Speaker 3 of 6 Yaeta Endo, Ehime University, Japan Advances in the Cell-Free Protein Production for Protein Biology
Monday, January 07 \| 8:00AM - 11:15AM Advances in Protein Production and Crystallization Room: Sunshine Speaker 4 of 6 Neil Isaacs, University of Glasgow, UK Methods of Membrane Protein Production
Monday, January 07 \| 8:00AM - 11:15AM Advances in Protein Production and Crystallization Room: Sunshine Speaker 5 of 6 Andrzej Joachimiak, Argonne National Laboratory, USA Lessons Learned from High-throughput Protein Production
Monday, January 07 \| 8:00AM - 11:15AM Advances in Protein Production and Crystallization Room: Sunshine Speaker 6 of 6 Ian A. Wilson, The Scripps Research Institute, USA Can We Predict Which Proteins Will Crystallize
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 1 of 7 * Juli Feigon, University of California, Los Angeles, USA
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 2 of 7 Charalampos Babis Kalodimos, St. Jude Children's Research Hospital, USA Structural Basis for the Assembly of Large Protein Machineries Determined by NMR: The Sec Translocase Machinery
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 3 of 7 Keiichi Namba, Osaka University, Japan Molecular Mechanisms of Self-Assembly and its Regulation of the Bacterial Flagellum
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 4 of 7 Erik R. P. Zuiderweg, University of Michigan, USA The Allosteric States of Hsp70 Chaperones Visualized by NMR
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 5 of 7 Juha P. Himanen, Sloan-Kettering Institute, USA Short Talk: Structural Studies on Eph Receptor-ephrin Recognition and Signaling
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 6 of 7 Mark D. Allen, Medical Research Council, UK Short Talk: FtsK: gamma Domain and KOPS Recognition
Monday, January 07 \| 8:00AM - 11:00AM Macromolecular Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 7 of 7 Chun Tang, Wuhan Institute of Physics and Mathematics, China Short Talk: Visualizing Transient Low-Population Intermediates by Paramagnetic Relaxation Enhancement
Monday, January 07 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Monday, January 07 \| 11:15AM - 12:00PM Open Meeting of the Protein Structure Initiative (PSI) Room: Sunshine Speaker 1 of 1 * John C. Norvell, NIGMS, National Institutes of Health, USA
Monday, January 07 \| 12:00PM - 1:00PM Poster Setup Room: Rainbow/Twilight/Sunset/Skyline
Monday, January 07 \| 1:00PM - 10:00PM Poster Viewing Room: Rainbow/Twilight/Sunset/Skyline
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 1 of 11 * Lance Stewart, Institute for Protein Design at University of Washington, USA
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 2 of 11 John Walchli, deCODE Biostructures, Inc., USA Gene Composer: A Construct and Codon Engineering Tool for Synthetic Structural Biology
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 3 of 11 Martin Hammarström, Karolinska Institute, Sweden The Use of Systematic N- and C-terminal Deletions to Promote Production and Structural Studies of Recombinant Proteins
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 4 of 11 Asli Ertekin, University of Massachusetts Medical School, USA Using Mass Spectrometry-based Amide Hydrogen/Deuterium Exchange in Optimizing Protein Constructs for NMR Structure Determination
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 5 of 11 David C. Wood, Pfizer, St. Louis, USA Parallel Protein Expression, Purification and Analysis for Structural Biology
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 6 of 11 David Cooper, Pfizer, USA The SER Salvage Strategy
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 7 of 11 Heath E. Klock, Genomics Institute of the Novartis Research Foundation, USA Salvage Pathways for Problematic Targets: Lessons Learned from Structural Genomics
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 8 of 11 Matthew D. Zimmerman, University of Virginia, USA Efficient Experimental Design and Quantitative Analysis of Crystallization Experiments with the Xtaldb Expert System
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 9 of 11 Edward H. Snell, Hauptman Woodward Medical Research Institute, USA Order from Chaos - the Design and Interpretation of High Throughput Crystallization Screens to Guide Optimization
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 10 of 11 Shohei Koide, New York University Langone Health, USA Protein Engineering Pipeline for Chaperone-Assisted Crystallography
Monday, January 07 \| 2:00PM - 4:30PM Workshop 1: Applications of Structural Genomics for Structur al Biology Room: Sunshine Speaker 11 of 11 Markus G. Grütter, University of Zurich, Switzerland Technological Advances for Supramolecular Assemblies
Monday, January 07 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Monday, January 07 \| 5:00PM - 7:00PM Pushing the Limits of Structural Biology I: Membrane Protein s (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 1 of 5 * Robert M. Stroud, University of California, San Francisco, USA
Monday, January 07 \| 5:00PM - 7:00PM Pushing the Limits of Structural Biology I: Membrane Protein s (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 2 of 5 Wayne A. Hendrickson, Columbia University, USA Ligand Stimulated Transitions in Nicotinic Acetylcholine Receptor á9
Monday, January 07 \| 5:00PM - 7:00PM Pushing the Limits of Structural Biology I: Membrane Protein s (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 3 of 5 Kurt Wüthrich, ETH Zürich, Switzerland Solution NMR Spectroscopy in Membrane Protein Structural Genomics
Monday, January 07 \| 5:00PM - 7:00PM Pushing the Limits of Structural Biology I: Membrane Protein s (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 4 of 5 Raymond Stevens, ShanghaiTech University and University of Southern California, USA High Resolution Crystal Structures of the Human b2-Adrenergic Receptor and Implications in GPCR Biology and Drug Discovery
Monday, January 07 \| 5:00PM - 7:00PM Pushing the Limits of Structural Biology I: Membrane Protein s (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 5 of 5 Tony Kossiakoff, University of Chicago, USA Short Talk: Structures of Open and Closed Forms of Full-Length KcsA Channel Using Chaperone-Assisted Crystallography: Application to Solving the Structure of the Closed and Open Forms of KcsA
Monday, January 07 \| 7:00PM - 8:00PM Social Hour Room: Rainbow/Twilight/Sunset/Skyline
Monday, January 07 \| 7:30PM - 10:00PM Poster Session 1: Protein Prediction, Structure Determinatio n and Methods Room: Rainbow/Twilight/Sunset/Skyline
Tuesday, January 08 \| 7:00AM - 8:00AM Breakfast Room: 3 Saddles/Bear River
Tuesday, January 08 \| 8:00AM - 11:00AM Advances in X-ray and NMR Structure Determination. Session Supported in part by Bruker BioSpin Corp. and Bruker AXS Inc. Room: Sunshine Speaker 1 of 6 * Kurt Wüthrich, ETH Zürich, Switzerland
Tuesday, January 08 \| 8:00AM - 11:00AM Advances in X-ray and NMR Structure Determination. Session Supported in part by Bruker BioSpin Corp. and Bruker AXS Inc. Room: Sunshine Speaker 2 of 6 Masatsune Kainosho, Nagoya University, Japan Stereo-Array Isotope Labeling (SAIL) for NMR
Tuesday, January 08 \| 8:00AM - 11:00AM Advances in X-ray and NMR Structure Determination. Session Supported in part by Bruker BioSpin Corp. and Bruker AXS Inc. Room: Sunshine Speaker 3 of 6 Michael Nilges, Institut Pasteur, France New Calculation Protocols for Analyzing NOE Data: Solid State NMR, Synmetric Multimers and Inconsistent Data
Tuesday, January 08 \| 8:00AM - 11:00AM Advances in X-ray and NMR Structure Determination. Session Supported in part by Bruker BioSpin Corp. and Bruker AXS Inc. Room: Sunshine Speaker 4 of 6 Victor S. Lamzin, BIOXHIT, Germany A Highly Integrated Platform for Structural Biology and Advances in Ligand Fitting
Tuesday, January 08 \| 8:00AM - 11:00AM Advances in X-ray and NMR Structure Determination. Session Supported in part by Bruker BioSpin Corp. and Bruker AXS Inc. Room: Sunshine Speaker 5 of 6 John A. Tainer, The Scripps Research Institute, USA Short Talk: X-ray Solution Scattering (SAXS) Combined with Crystallography and Computation: Defining Accurate Dynamic Macromolecular Assemblies in Solution
Tuesday, January 08 \| 8:00AM - 11:00AM Advances in X-ray and NMR Structure Determination. Session Supported in part by Bruker BioSpin Corp. and Bruker AXS Inc. Room: Sunshine Speaker 6 of 6 David Baker, University of Washington, USA Structure Determination and Refinement from Limited Experimental Data Using Rosetta
Tuesday, January 08 \| 8:00AM - 11:00AM Macromolecular Dynamics: Experiment and Theory This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 1 of 6 * Gerhard Wagner, Harvard Medical School, USA
Tuesday, January 08 \| 8:00AM - 11:00AM Macromolecular Dynamics: Experiment and Theory This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 2 of 6 Klaus J. Schulten, University of Illinois at Urbana-Champaign, USA The Computational Microscope: Multiscale Modeling of Cellular Systems
Tuesday, January 08 \| 8:00AM - 11:00AM Macromolecular Dynamics: Experiment and Theory This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 3 of 6 Michele Vendruscolo, University of Cambridge, UK Simultaneous Determination of Protein Structure and Dynamics
Tuesday, January 08 \| 8:00AM - 11:00AM Macromolecular Dynamics: Experiment and Theory This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 4 of 6 Dorothee Kern, Brandeis University, HHMI, USA A Hierarchy of Space and Time in Protein Dynamics - Linkage to Catalysis and Signaling
Tuesday, January 08 \| 8:00AM - 11:00AM Macromolecular Dynamics: Experiment and Theory This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 5 of 6 Peter E. Wright, The Scripps Research Institute, USA The Dynamic Energy Landscape of DHFR Catalysis
Tuesday, January 08 \| 8:00AM - 11:00AM Macromolecular Dynamics: Experiment and Theory This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 6 of 6 A. Joshua Wand, University of Pennsylvania, USA Short Talk: Using Dynamics as a Proxy for Entropy: Applications of NMR Relaxation to Studies of the Origin of High Affinity Association by Calmodulin
Tuesday, January 08 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Tuesday, January 08 \| 11:00AM - 1:00PM Poster Setup Room: Rainbow/Twilight/Sunset/Skyline
Tuesday, January 08 \| 1:00PM - 10:00PM Poster Viewing Room: Rainbow/Twilight/Sunset/Skyline
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 1 of 11 * Andrzej Joachimiak, Argonne National Laboratory, USA
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 2 of 11 Cory J. Gerdts, Protein BioSolutions, USA The Microfluidic Protein Crystallization System (MPCS)
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 3 of 11 Andrew May, Sana Biotechnology, Inc., USA Diffraction-Capable Microfluidic Crystallization Chips for Screening and Structure Determination
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 4 of 11 Stephen R. Wasserman, SGX Pharmaceuticals, Inc, USA The Integration of Rapid Synchrotron-based X-ray Crystallography into Structural Genomics and Drug Development: The SGX-CAT Beamline at the Advanced Photon Source
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 5 of 11 Wuxian Shi, Brookhaven National Laboratory, USA Metalloproteomics - High Throughput Metal Analysis of Proteins
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 6 of 11 Wladek Minor, University of Virginia, USA HKL-3000 - Towards the Future of Protein Crystallography
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 7 of 11 Dušan Turk, Jozef Stefan Institute, Slovenia MAIN Entering 2008: Real Space Model Fitting – As Good As It Gets
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 8 of 11 George N. Phillips, Jr., University of Wisconsin, CESG, USA Map Interpretation and Ensemble Refinements
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 9 of 11 Ashley M. Deacon, Stanford Synchrotron Radiation Laboratory, USA Maintaining High Quality Structure Depositions at JCSG
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 10 of 11 Thomas Andrew Binkowski, Argonne National Laboratory, USA Comparison and Analysis of Protein Functional Surfaces
Tuesday, January 08 \| 2:00PM - 4:30PM Workshop 2: Advances in Methodologies/Tools for Structural G enomics and Structural Biology Room: Sunshine Focusing on hardware, software, devices and databases. Speaker 11 of 11 Subramanian Sri Krishna, Sanford-Burnham Medical Research Institute, USA TOPSAN: A Community-driven Protein Knowledgebase for Structural Genomics
Tuesday, January 08 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Tuesday, January 08 \| 5:00PM - 7:15PM Ligands as Probes for Function Room: Sunshine Speaker 1 of 6 * Stephen K. Burley, Rutgers University, USA
Tuesday, January 08 \| 5:00PM - 7:15PM Ligands as Probes for Function Room: Sunshine Speaker 2 of 6 Benjamin F. Cravatt III, The Scripps Research Institute, USA Metabolomics and its Role in Enzyme Function Assignment
Tuesday, January 08 \| 5:00PM - 7:15PM Ligands as Probes for Function Room: Sunshine Speaker 3 of 6 Janet M. Thornton, European Bioinformatics Institute, UK Diversity of Ligands within Protein Families
Tuesday, January 08 \| 5:00PM - 7:15PM Ligands as Probes for Function Room: Sunshine Speaker 4 of 6 Aled M. Edwards, University of Toronto, Canada Screening for Function
Tuesday, January 08 \| 5:00PM - 7:15PM Ligands as Probes for Function Room: Sunshine Speaker 5 of 6 Chang-Yub Kim, Los Alamos National Laboratory, USA Short Talk: Development of a High-Throughput Ligand Screening Technique and Application to Structural Genomics
Tuesday, January 08 \| 5:00PM - 7:15PM Ligands as Probes for Function Room: Sunshine Speaker 6 of 6 Maurizio Pellecchia, University of California, Riverside, USA Short Talk: Targeting Apoptosis by Chemical Design: NMR Guided Reverse Chemical Genetics and Drug Discovery
Tuesday, January 08 \| 5:00PM - 7:15PM Membrane Protein Structure This session is from Structural Biology Room: Sunshine/Mt. Werner/Storm Peak Speaker 1 of 6 * Alasdair C. Steven, NIAMS, National Institutes of Health, USA
Tuesday, January 08 \| 5:00PM - 7:15PM Membrane Protein Structure This session is from Structural Biology Room: Sunshine/Mt. Werner/Storm Peak Speaker 2 of 6 Carola Hunte, University of Leeds, UK Cytochrome c Binding to the Cytochrome bc1 Complex: An Interaction Critical for Electron Transfer
Tuesday, January 08 \| 5:00PM - 7:15PM Membrane Protein Structure This session is from Structural Biology Room: Sunshine/Mt. Werner/Storm Peak Speaker 3 of 6 James Jeiwen Chou, Harvard Medical School, USA Structure and Mechanism of the M2 Proton Channel of Influenza A Virus
Tuesday, January 08 \| 5:00PM - 7:15PM Membrane Protein Structure This session is from Structural Biology Room: Sunshine/Mt. Werner/Storm Peak Speaker 4 of 6 William I. Weis, Stanford University, USA Two Crystal Structures of the b2-Adrenergic Receptor
Tuesday, January 08 \| 5:00PM - 7:15PM Membrane Protein Structure This session is from Structural Biology Room: Sunshine/Mt. Werner/Storm Peak Speaker 5 of 6 Lukas K. Tamm, University of Virginia, USA Short Talk: Solution NMR Structure of the 33 kDa Outer Membrane Protein G
Tuesday, January 08 \| 5:00PM - 7:15PM Membrane Protein Structure This session is from Structural Biology Room: Sunshine/Mt. Werner/Storm Peak Speaker 6 of 6 Daniel Martinez Molina, Karolinska Institutet, Sweden Short Talk: Structure and Mechanism of Human Leukotriene C4 Synthase
Tuesday, January 08 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Rainbow/Twilight/Sunset/Skyline
Tuesday, January 08 \| 7:30PM - 10:00PM Poster Session 2: Macromolecular Structure and Function Room: Rainbow/Twilight/Sunset/Skyline
Wednesday, January 09 \| 7:00AM - 8:00AM Breakfast Room: 3 Saddles/Bear River
Wednesday, January 09 \| 8:00AM - 11:00AM Exploiting the Expanding Protein Universe Room: Sunshine Speaker 1 of 6 * Andrej Sali, University of California, San Francisco, USA
Wednesday, January 09 \| 8:00AM - 11:00AM Exploiting the Expanding Protein Universe Room: Sunshine Speaker 2 of 6 Jo Handelsman, University of Wisconsin-Madison, USA Structure and Function of Microbial Communities
Wednesday, January 09 \| 8:00AM - 11:00AM Exploiting the Expanding Protein Universe Room: Sunshine Speaker 3 of 6 Robert M. Stroud, University of California, San Francisco, USA Membrane Proteomics
Wednesday, January 09 \| 8:00AM - 11:00AM Exploiting the Expanding Protein Universe Room: Sunshine Speaker 4 of 6 John Moult, University of Maryland Biotechnology Institute, USA Expanding Structure Coverage of the Protein Universe with Comparative Modeling
Wednesday, January 09 \| 8:00AM - 11:00AM Exploiting the Expanding Protein Universe Room: Sunshine Speaker 5 of 6 Helen M. Berman, Rutgers University, Center for Proteomics Research, USA Short Talk: Harnessing Knowledge from Structural Genomics: the PSI Knowledgebase
Wednesday, January 09 \| 8:00AM - 11:00AM Exploiting the Expanding Protein Universe Room: Sunshine Speaker 6 of 6 Gaetano Thomas Montelione, Rutgers University, USA Short Talk: Structural Genomics Provides Novel Hypotheses for Biology
Wednesday, January 09 \| 8:00AM - 11:00AM Protein – Nucleic Acid Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 1 of 6 * Christopher D. Lima, Memorial Sloan Kettering Cancer Center, USA
Wednesday, January 09 \| 8:00AM - 11:00AM Protein – Nucleic Acid Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 2 of 6 Michael Sattler, Helmholtz Zentrum München & Technische Universität München, Germany Molecular Recognition in Splicing Regulation
Wednesday, January 09 \| 8:00AM - 11:00AM Protein – Nucleic Acid Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 3 of 6 Juli Feigon, University of California, Los Angeles, USA Structure and Function of Human Telomerase and H/ACA RNA
Wednesday, January 09 \| 8:00AM - 11:00AM Protein – Nucleic Acid Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 4 of 6 Eric Enemark, Cold Spring Harbor Laboratory, USA Mechanism of DNA Translocation in a Replicative Hexameric Helicase
Wednesday, January 09 \| 8:00AM - 11:00AM Protein – Nucleic Acid Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 5 of 6 Elena Conti, Max Planck Institute of Biochemistry, Germany The Exon Junction Complex and mRNA Qualitry Control
Wednesday, January 09 \| 8:00AM - 11:00AM Protein – Nucleic Acid Interactions This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 6 of 6 Marianna Teplova, Memorial Sloan-Kettering Cancer Center, USA Short Talk: Recognition of the pre-mRNA GC and GCU Elements by Tandem Zinc Finger Domains of Muscleblind Protein MBNL1
Wednesday, January 09 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Wednesday, January 09 \| 11:00AM - 1:00PM Poster Setup Room: Sunshine
Wednesday, January 09 \| 1:00PM - 10:00PM Poster Viewing Room: Sunshine
Wednesday, January 09 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Wednesday, January 09 \| 5:00PM - 7:30PM Pushing the Limits of Structural Biology II: Advances in Met hodologies for Structure Determination (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 1 of 6 * Wayne A. Hendrickson, Columbia University, USA
Wednesday, January 09 \| 5:00PM - 7:30PM Pushing the Limits of Structural Biology II: Advances in Met hodologies for Structure Determination (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 2 of 6 Hartmut Oschkinat, FMP Berlin, Germany Solid State NMR Methods for Protein Structure Determination
Wednesday, January 09 \| 5:00PM - 7:30PM Pushing the Limits of Structural Biology II: Advances in Met hodologies for Structure Determination (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 3 of 6 Gerhard Wagner, Harvard Medical School, USA Protein Complexes that Regulate Polypeptide Synthesis
Wednesday, January 09 \| 5:00PM - 7:30PM Pushing the Limits of Structural Biology II: Advances in Met hodologies for Structure Determination (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 4 of 6 Carolyn A. Larabell, University of California, San Francisco, USA X-ray Tomography of Whole Cells at 50 nm Resolution
Wednesday, January 09 \| 5:00PM - 7:30PM Pushing the Limits of Structural Biology II: Advances in Met hodologies for Structure Determination (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 5 of 6 Wolfgang P. Baumeister, Max Planck Institute of Biochemistry, Germany Mapping Molecular Landscapes Inside Cells by Cryoelectron Tomography
Wednesday, January 09 \| 5:00PM - 7:30PM Pushing the Limits of Structural Biology II: Advances in Met hodologies for Structure Determination (Joint) Room: Sunshine/Mt. Werner/Storm Peak Speaker 6 of 6 Andreas Hoenger, University of Colorado, Boulder, USA Short Talk: PEET (Particle Estimation for Electron Tomography: A New Software Package for 3D Alignment and Averaging of Volume
Wednesday, January 09 \| 7:30PM - 8:30PM Social Hour with Lite Bites Room: Rainbow/Twilight/Sunset/Skyline
Wednesday, January 09 \| 8:00PM - 10:00PM Workshop on World-Wide Structural Genomic and Structural Pro teomic Centers Room: Sunshine Structural genomic, structural proteomic and protein production centers and consortia present their platforms to highlight new methods, technologies, databases, and computational tools that have enabled advances in protein production and structure determination for all classes of targets from bacterial to challenging macromolecules , such as membrane proteins, eukaryotic proteins and protein-protein complexes. An emphasis will be placed on what can now be utilized by the entire community, including single investigator laboratories to increase success and throughput and lower costs.
Thursday, January 10 \| 7:00AM - 8:00AM Breakfast Room: 3 Saddles/Bear River
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 1 of 7 * Janet M. Thornton, European Bioinformatics Institute, UK
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 2 of 7 Andrej Sali, University of California, San Francisco, USA Modeling the Structures of Macromolecular Assemblies
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 3 of 7 David Eisenberg, University of California, Los Angeles, USA Protein Assemblies in Health and Disease
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 4 of 7 Rudolf H. Aebersold, Institute of Molecular Systems Biology, ETH Zürich, Switzerland On the Characterization of Protein Complexes and Protein Interaction Networks
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 5 of 7 Adam Godzik, Sanford-Burnham Medical Research Institute, USA Metabolic Reconstruction of Thermatoga Maritima
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 6 of 7 Alexander B. Sigalov, SignaBlok, Inc., USA Short Talk: Homointeractions between Intrinsically Disordered Proteins: Unusual Structural Features and a Role in Immune Signaling
Thursday, January 10 \| 8:00AM - 11:15AM Proteomics and Protein Assemblies/Networks Room: Sunshine Speaker 7 of 7 Akira Nozawa, Ehime University, Japan Short Talk: A Cell-free System-based Method for Comprehensive Analysis of DNA Binding to Human Hormone Nuclear Receptors by Fluorescence Correlation Spectroscopy
Thursday, January 10 \| 8:00AM - 11:00AM Large Macromolecular Complexes This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 1 of 5 * Elena Conti, Max Planck Institute of Biochemistry, Germany
Thursday, January 10 \| 8:00AM - 11:00AM Large Macromolecular Complexes This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 2 of 5 Nenad Ban, ETH Zürich, Switzerland Springs, Tethers and Switchblades: Mechanistic Insights into the Functioning of Large Macromolecular Assemblies Involed in Protein and Fatty Acid Synthesis
Thursday, January 10 \| 8:00AM - 11:00AM Large Macromolecular Complexes This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 3 of 5 Carol V. Robinson, University of Oxford, UK Mass Spectrometry and the Determination of Complex Architecture
Thursday, January 10 \| 8:00AM - 11:00AM Large Macromolecular Complexes This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 4 of 5 Venki Ramakrishnan, MRC Laboratory of Molecular Biology, UK Structure of the 70A Ribosome
Thursday, January 10 \| 8:00AM - 11:00AM Large Macromolecular Complexes This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 5 of 5 Christopher D. Lima, Memorial Sloan Kettering Cancer Center, USA RNA Structure and Activities of the Eukaryotic RNA Exosome
Thursday, January 10 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Thursday, January 10 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Thursday, January 10 \| 5:00PM - 7:00PM Exploiting Structure for Function Room: Sunshine Speaker 1 of 5 * Gaetano Thomas Montelione, Rutgers University, USA
Thursday, January 10 \| 5:00PM - 7:00PM Exploiting Structure for Function Room: Sunshine Speaker 2 of 5 Stephen K. Burley, Rutgers University, USA Structural Genomics of Protein Phosphatases
Thursday, January 10 \| 5:00PM - 7:00PM Exploiting Structure for Function Room: Sunshine Speaker 3 of 5 Stefan Knapp, University of Oxford, UK The Protein Kinase Family
Thursday, January 10 \| 5:00PM - 7:00PM Exploiting Structure for Function Room: Sunshine Speaker 4 of 5 Christine A. Orengo, University College London, UK Short Talk: Structural Genomics to Explore the Evolution of Protein Function
Thursday, January 10 \| 5:00PM - 7:00PM Exploiting Structure for Function Room: Sunshine Speaker 5 of 5 Peter Kuhn, The Scripps Research Institute, USA Proteomic Analysis of nsp3, a Multifunctional 1922 Amino Acid Polypeptide in SARS CoV
Thursday, January 10 \| 5:00PM - 7:00PM Virus Structure and Assembly This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 1 of 4 * Michael G. Rossmann, Purdue University, USA
Thursday, January 10 \| 5:00PM - 7:00PM Virus Structure and Assembly This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 2 of 4 David I. Stuart, Oxford University, UK The Virosphere - Insights from the Analysis of Complex Viruses
Thursday, January 10 \| 5:00PM - 7:00PM Virus Structure and Assembly This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 3 of 4 Alasdair C. Steven, NIAMS, National Institutes of Health, USA Beyond Determinism: Coming to Terms with Variability in Virus Structures
Thursday, January 10 \| 5:00PM - 7:00PM Virus Structure and Assembly This session is from Structural Biology Room: Mt. Werner/Storm Peak Speaker 4 of 4 Michael F. Summers, HHMI/University of Maryland, Baltimore County, USA Structural Studies of Large RNAs Involved in Retroviral Genome Packaging
Thursday, January 10 \| 8:00PM - 9:00PM Social Hour with Lite Bites Room: Foyer
Thursday, January 10 \| 9:00PM - 11:00PM Entertainment Room: Sunshine
Thursday, January 10 \| 9:00PM - 11:00PM Cash Bar Room: Sunshine
Friday, January 11 \| 10:21AM - 10:21AM Departure *Session Chair †Invited, not yet responded.