Web Desc
Epigenetics, Development and Human Disease
Organizer(s): Anne Ferguson-Smith and Steven Henikoff
Date: January 05 - 10, 2009
Location: Beaver Run Resort, Breckenridge, CO, USA
Supported by the Directors' Fund
For important information on the coronavirus, please click here
Summary of Meeting:
This meeting aims to provide a stimulating forum for exploring the epigenetic control of genome function illustrated through the regulation of a variety of biological processes in a range of model organisms. The role of factors influencing chromatin organization and chromosome architecture, and the dynamic changes in epigenetic state that regulate development, are two well-established but fast-moving areas that will be covered. The dynamic nature of epigenetic states renders them both adaptable and vulnerable; this will be explored in sessions considering the influence of the environment on epigenetic control, and the causes and consequences of epigenetic change in disease. We anticipate that the data presented will allow evolutionary insights and functional comparison of epigenetic mechanisms in different organisms and systems, resulting in the integration of ideas to generate new concepts and a deeper understanding in this field.
Scholarship Deadline: September 15 2008
Discounted Abstract Deadline: September 15 2008
Abstract Deadline: October 8 2008
Discounted Registration Deadline: November 5 2008
We gratefully acknowledge additional support for this conference from:
CellCentric Ltd.Integrated DNA Technologies
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
BioMed CentralCell PressRoyal Society of Chemistry
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Environmental Health Sciences (NIEHS)
Grant No. 1R13ES016960-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Monday, January 05 | 3:00PM - 7:30PM
Registration
Room: Foyer


Monday, January 05 | 6:30PM - 7:30PM
Refreshments
Room: Foyer


Monday, January 05 | 7:30PM - 8:30PM
Keynote Address
Room: Colorado Ballroom

Speaker 1 of 3
Anne C. Ferguson-Smith, University of Cambridge, UK
Opening and Welcoming Greeting

Monday, January 05 | 7:30PM - 8:30PM
Keynote Address
Room: Colorado Ballroom

Speaker 2 of 3
* Steven Henikoff, Fred Hutchinson Cancer Research Center, USA

Monday, January 05 | 7:30PM - 8:30PM
Keynote Address
Room: Colorado Ballroom

Speaker 3 of 3
Huntington F. Willard, Duke University, USA
Epigenetics in Complex Genomes: What's the Genome Do?

Monday, January 05 | 8:30PM - 9:30PM
Orientation for New Attendees and New Investigators
Room: Colorado Ballroom
Keystone Symposia's Chief Scientific Officer, Dr. Andy Robertson, to lead discussion in a 'What to Expect during your Attendance' for interested delegates.

Tuesday, January 06 | 7:00AM - 8:00AM
Breakfast
Room: Summit Gallery


Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 1 of 7
* Barbara J. Meyer, University of California, Berkeley, USA

Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 2 of 7
Bradley R. Cairns, HHMI/University of Utah, USA
DNA Methylation Dynamics in Zebrafish Embryos

Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 3 of 7
Steven Henikoff, Fred Hutchinson Cancer Research Center, USA
Histone Variants and Chromatin Dynamics

Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 4 of 7
Jessica K. Tyler, Weill Cornell Medicine, USA
Novel Roles for Core Histone Acetylation on H3 lysine 56 in Longevity and Tumorigenesis

Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 5 of 7
Geneviève Almouzni, Centre National de la Recherche Scientifique, France
During Cell Cycle - Challenges of DNA Replication and Repair

Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 6 of 7
Petra Hajkova, Imperial College London, UK
Short Talk: Mechanistic Aspects of DNA Demethylation in Mouse Development

Tuesday, January 06 | 8:00AM - 11:15AM
Chromatin Dynamics
Room: Colorado Ballroom

Speaker 7 of 7
Craig S. Pikaard, HHMI/Indiana University, USA
Short Talk: Plant RNA Polymerases IV and V: Subunit Structures and Modes of Action in RNA-Directed DNA Methylation

Tuesday, January 06 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Tuesday, January 06 | 11:15AM - 11:15AM
On Own for Lunch


Tuesday, January 06 | 11:15AM - 1:00PM
Poster Setup
Room: Breckenridge Ballroom


Tuesday, January 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Breckenridge Ballroom


Tuesday, January 06 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, January 06 | 5:00PM - 7:00PM
Functional Organization of the Nucleus
Room: Colorado Ballroom

Speaker 1 of 5
* Amanda G. Fisher, Imperial College London, UK

Tuesday, January 06 | 5:00PM - 7:00PM
Functional Organization of the Nucleus
Room: Colorado Ballroom

Speaker 2 of 5
Jeannie T. Lee, Massachusetts General Hospital / Harvard Medical School, USA
Imprinted X Chromosome Inactivation

Tuesday, January 06 | 5:00PM - 7:00PM
Functional Organization of the Nucleus
Room: Colorado Ballroom

Speaker 3 of 5
Gary Karpen, University of California, Berkeley, USA
DNA Repair in Heterochromatin

Tuesday, January 06 | 5:00PM - 7:00PM
Functional Organization of the Nucleus
Room: Colorado Ballroom

Speaker 4 of 5
Peter Fraser, Florida State University, USA
The Role of the Air Non-Coding RNA in Gene Silencing

Tuesday, January 06 | 5:00PM - 7:00PM
Functional Organization of the Nucleus
Room: Colorado Ballroom

Speaker 5 of 5
Jane A. Skok, New York University School of Medicine, USA
Short Talk: Recombinase-Dependent Homologous Pairing of Ig Alleles: A Novel Regulatory Aspect of Allelic Exclusion

Tuesday, January 06 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom


Tuesday, January 06 | 7:30PM - 10:00PM
Poster Session 1
Room: Breckenridge Ballroom


Wednesday, January 07 | 7:00AM - 8:00AM
Breakfast
Room: Summit Gallery


Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 1 of 7
* Geneviève Almouzni, Centre National de la Recherche Scientifique, France

Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 2 of 7
William G. Kelly, Emory University, USA
Chromatin Remodeling and Erasure during C. elegans Germline Specification

Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 3 of 7
Vincenzo Pirrotta, Rutgers University, USA
Alternative Chromatin States of Polycomb Target Genes

Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 4 of 7
Barbara J. Meyer, University of California, Berkeley, USA
Targeting X-Chromosome Repression

Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 5 of 7
Asifa Akhtar, Max Planck Institute of Immunobiology and Epigenetics, Germany
Dosage Compensation

Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 6 of 7
Sam Schoenmakers, Erasmus University Medical Center, Netherlands
Short Talk: Meiotic Sex Chromosome Inactivation in the Female Germline

Wednesday, January 07 | 8:00AM - 11:15AM
Long-Range Epigenetic Control during Development
Room: Colorado Ballroom

Speaker 7 of 7
Patrick J. E. C. Wijchers, Hubrecht Institute, Netherlands
Short Talk: Sexual Dimorphisms in Mammals

Wednesday, January 07 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Wednesday, January 07 | 11:15AM - 11:15AM
On Own for Lunch


Wednesday, January 07 | 11:15AM - 1:00PM
Poster Setup
Room: Breckenridge Ballroom


Wednesday, January 07 | 1:00PM - 10:00PM
Poster Viewing
Room: Breckenridge Ballroom


Wednesday, January 07 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, January 07 | 5:00PM - 7:00PM
Integrated Epigenetic Mechanisms
Room: Colorado Ballroom

Speaker 1 of 5
* William G. Kelly, Emory University, USA

Wednesday, January 07 | 5:00PM - 7:00PM
Integrated Epigenetic Mechanisms
Room: Colorado Ballroom

Speaker 2 of 5
Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Copying and Reprogramming of Heterochromatin with RNAi

Wednesday, January 07 | 5:00PM - 7:00PM
Integrated Epigenetic Mechanisms
Room: Colorado Ballroom

Speaker 3 of 5
Jonathan I. Gent, University of Georgia, USA
Short Talk: A Small RNA Mediated, Paternal Contribution to C. elegans Embryogenesis?

Wednesday, January 07 | 5:00PM - 7:00PM
Integrated Epigenetic Mechanisms
Room: Colorado Ballroom

Speaker 4 of 5
Steven E. Jacobsen, University of California, Los Angeles, USA
DNA Methylation in Arabidopsis

Wednesday, January 07 | 5:00PM - 7:00PM
Integrated Epigenetic Mechanisms
Room: Colorado Ballroom

Speaker 5 of 5
Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA
Interactions between DNA Methylation and Histone Modifications in Mammals

Wednesday, January 07 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom


Wednesday, January 07 | 7:30PM - 10:00PM
Poster Session 2
Room: Breckenridge Ballroom


Thursday, January 08 | 7:00AM - 8:00AM
Breakfast
Room: Summit Gallery


Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 1 of 7
* Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA

Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 2 of 7
James Turner, National Institute of Medical Research, UK
Meiotic Silencing in Mammals

Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 3 of 7
Sundeep Kalantry, University of Michigan Medical School, USA
Short Talk: Evolution of Xist-Requirement in the Initiation of Mouse Imprinted X-Chromosome Inactivation

Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 4 of 7
Robert L. Fischer, University of California, Berkeley, USA
Imprinting in Plants

Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 5 of 7
Wolf Reik, Babraham Institute, UK
Epigenetic Regulation of Imprinting, Reprogramming, and Lineage Commitment in Mammalian Development

Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 6 of 7
Urszula Brykczynska, Friedrich Miescher Institute, Switzerland
Short talk: Transmission of Methylated Histones with Modifications Specific Genomic Localization by Human Spermatozoa

Thursday, January 08 | 8:00AM - 11:00AM
Parental Origin-Specific Epigenetic Processes
Room: Colorado Ballroom

Speaker 7 of 7
Nico Ruf, Babraham Institute, UK
Short Talk: Transcription is Required for Establishment of Germline Methylation Marks at Imprinted Genes

Thursday, January 08 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Thursday, January 08 | 11:00AM - 11:00AM
On Own for Lunch


Thursday, January 08 | 11:00AM - 1:00PM
Poster Setup
Room: Breckenridge Ballroom


Thursday, January 08 | 1:00PM - 10:00PM
Poster Viewing
Room: Breckenridge Ballroom


Thursday, January 08 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, January 08 | 5:00PM - 7:00PM
Environmental Modulation of Epigenetic States
Room: Colorado Ballroom

Speaker 1 of 5
* Michael Meaney, McGill University, Canada

Thursday, January 08 | 5:00PM - 7:00PM
Environmental Modulation of Epigenetic States
Room: Colorado Ballroom

Speaker 2 of 5
Paul D. Soloway, Cornell University, USA
Antagonism Between DNA and H3K27 Methylation at the Imprinted Rasgrf1 Locus

Thursday, January 08 | 5:00PM - 7:00PM
Environmental Modulation of Epigenetic States
Room: Colorado Ballroom

Speaker 3 of 5
E. Jean Finnegan, CSIRO Plant Industry, Australia
Epigenetic Determinants of an Environmental Response

Thursday, January 08 | 5:00PM - 7:00PM
Environmental Modulation of Epigenetic States
Room: Colorado Ballroom

Speaker 4 of 5
Jay C. Dunlap, Dartmouth Medical School, USA
Short Talk: DNA Methylation, the frq Antisense Transcript qrf, and the ATP-Dependent Chromatin-Remodeling Enzyme CHD2: Roles in the Epigenetic Transfer of Circadian Time

Thursday, January 08 | 5:00PM - 7:00PM
Environmental Modulation of Epigenetic States
Room: Colorado Ballroom

Speaker 5 of 5
Frédéric L. Chedin, University of California, Davis, USA
Short talk: The DNMT3L Protein Interacts with Multiple Nucleosomal Components to Guide de novo Methylation

Thursday, January 08 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom


Thursday, January 08 | 7:30PM - 10:00PM
Poster Session 3
Room: Breckenridge Ballroom


Friday, January 09 | 7:00AM - 8:00AM
Breakfast
Room: Summit Gallery


Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 1 of 7
* Wolf Reik, Babraham Institute, UK

Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 2 of 7
Amanda G. Fisher, Imperial College London, UK
Epigenetic Regulators of Pluripotency

Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 3 of 7
Matthias Merkenschlager, Imperial College London, UK
Cohesins in Gene Regulation and Genome Organisation

Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 4 of 7
Gerald R. Crabtree, Stanford University, USA
Understanding the Words of Chromatin Remodeling

Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 5 of 7
Michael Meaney, McGill University, Canada
Epigenetic Programming of Behavior and Physiology

Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 6 of 7
Simon C. Biddie, University of Bristol, UK
Short Talk: Cell-Specific Interactions of the Glucocorticoid Receptor with Chromatin

Friday, January 09 | 8:00AM - 11:15AM
Vertebrate Developmental Epigenetics
Room: Colorado Ballroom

Speaker 7 of 7
Qiaoning Guan, University of California, Berkeley, USA
Short Talk: Nutritional Epigenomics in Yeasts and Human

Friday, January 09 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Friday, January 09 | 11:15AM - 11:15AM
On Own for Lunch


Friday, January 09 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Friday, January 09 | 5:00PM - 7:00PM
Epigenetic Mechanisms of Disease
Room: Colorado Ballroom

Speaker 1 of 5
* E. Jean Finnegan, CSIRO Plant Industry, Australia

Friday, January 09 | 5:00PM - 7:00PM
Epigenetic Mechanisms of Disease
Room: Colorado Ballroom

Speaker 2 of 5
Arthur L. Beaudet, Baylor College of Medicine, USA
The Role of Epigenetics in Neurobehavioral Disorders

Friday, January 09 | 5:00PM - 7:00PM
Epigenetic Mechanisms of Disease
Room: Colorado Ballroom

Speaker 3 of 5
Kristian Helin, University of Copenhagen and Memorial Sloan Kettering Cancer Center, Denmark
Histone Methylation at the Center of Cellular Differentiation and Disease

Friday, January 09 | 5:00PM - 7:00PM
Epigenetic Mechanisms of Disease
Room: Colorado Ballroom

Speaker 4 of 5
Andrew G. Clark, Cornell University, USA
Short Talk: Transcriptome-Wide Identification of Novel Imprinted Genes in Neonatal Mouse Brain

Friday, January 09 | 5:00PM - 7:00PM
Epigenetic Mechanisms of Disease
Room: Colorado Ballroom

Speaker 5 of 5
Andrew Chess, Massachusetts General Hospital, USA
Genome-Wide Allele-Specific Epigenomic Analyses

Friday, January 09 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Breckenridge Ballroom


Friday, January 09 | 8:00PM - 11:00PM
Entertainment
Room: Breckenridge Ballroom


Friday, January 09 | 8:00PM - 11:00PM
Cash Bar
Room: Breckenridge Ballroom


Saturday, January 10 | 10:22AM - 10:22AM
Departure


*Session Chair
†Invited, not yet responded.