Angiogenesis and Lymphangiogenesis in Cancer

Organizer(s): Lee M. Ellis and Luisa Iruela-Arispe

Sponsored by Genentech BioOncology, ImClone Systems Corporation and sanofi-aventis

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Summary of Meeting:

A concrete understanding of the mechanisms that regulate tumor angiogenesis has led to advances in the clinic; however multiple challenges remain. First, not all tumors or tumor types respond equally well to anti-VEGF therapy. And for those that do, many, if not all, eventually become refractory to anti-VEGF therapies. It is essential to understand the various factors that lead to the development and function of the neovascular network in tumors in order to improve therapies and identify predictive markers. In addition, understanding basic mechanisms of angiogenesis will lead to insights into other diseases where neovascularization is an important factor in the progression or resolution of the pathology. This symposium will provide a forum to discuss the current status of anti-angiogenic therapy, new insights into the molecular and morphologic abnormalities of the tumor vascular network, methods to investigate mechanisms of angiogenesis, the relationship of the tumor microenvironment to vascular and tumor stem cells, and elucidation of recently discovered mediators of angiogenesis.

Scholarship Deadline: September 15 2008

Discounted Abstract Deadline: September 15 2008

Abstract Deadline: October 9 2008

Discounted Registration Deadline: November 6 2008

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genzyme Corporation

Regeneron Pharmaceuticals, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA135834-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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