Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Pain: Aligning the Target (2020J7)
The Brain: Adaptation and Maladaptation in Chronic Pain (2014E3)

Web Desc
The Neurobiology of Pain and Analgesia Organizer(s): Clifford J. Woolf, Ardem Patapoutian and Simon Tate Date: February 22 - 27, 2009 Location: Hilton Santa Fe Historic Plaza Hotel, Santa Fe, NM, USA Sponsored by Abbott Laboratories and AstraZeneca Pharmaceuticals, L.P. Summary of Meeting: This symposium will highlight the substantial advances made in our understanding of the neurobiology and pathophysiology of pain and the enormous opportunities these present for identifying and exploiting new targets for therapy. Current therapy is largely empirical and is based on suppressing symptoms. The future offers treatment targeted at the specific neural mechanisms responsible. This requires understanding the mechanisms, being able to identify which mechanism operates in which patient, and having pharmacological tools to act on the molecular targets that drive these mechanisms. Furthermore, we need to identify which patient is at risk of developing pain and develop preventative disease-modifying treatments to abort the establishment of pain. This symposium will address how these goals can be achieved by the combined effort of academics and industry. Scholarship Deadline: October 21 2008 Discounted Abstract Deadline: October 21 2008 Abstract Deadline: November 21 2008 Discounted Registration Deadline: December 22 2008 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Educational grant from Lilly USA, LLC GlaxoSmithKline Pfizer Global Research & Development Pfizer Inc. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Neurological Disorders and Stroke (NINDS) Grant No. 1R13NS064604-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

The Neurobiology of Pain and Analgesia

Organizer(s): Clifford J. Woolf, Ardem Patapoutian and Simon Tate

Date: February 22 - 27, 2009
Location: Hilton Santa Fe Historic Plaza Hotel, Santa Fe, NM, USA

Sponsored by Abbott Laboratories and AstraZeneca Pharmaceuticals, L.P.

Summary of Meeting:

This symposium will highlight the substantial advances made in our understanding of the neurobiology and pathophysiology of pain and the enormous opportunities these present for identifying and exploiting new targets for therapy. Current therapy is largely empirical and is based on suppressing symptoms. The future offers treatment targeted at the specific neural mechanisms responsible. This requires understanding the mechanisms, being able to identify which mechanism operates in which patient, and having pharmacological tools to act on the molecular targets that drive these mechanisms. Furthermore, we need to identify which patient is at risk of developing pain and develop preventative disease-modifying treatments to abort the establishment of pain. This symposium will address how these goals can be achieved by the combined effort of academics and industry.

Scholarship Deadline: October 21 2008

Discounted Abstract Deadline: October 21 2008

Abstract Deadline: November 21 2008

Discounted Registration Deadline: December 22 2008

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Educational grant from Lilly USA, LLC

GlaxoSmithKline

Pfizer Global Research & Development

Pfizer Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Neurological Disorders and Stroke (NINDS)
Grant No. 1R13NS064604-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, February 22 \| 3:00PM - 7:30PM Registration Room: Promenade
Sunday, February 22 \| 6:30PM - 7:30PM Refreshments Room: Promenade
Sunday, February 22 \| 7:30PM - 9:30PM Keynote Session Room: Mesa A-B Speaker 1 of 4 * Clifford J. Woolf, Children's Hospital, USA
Sunday, February 22 \| 7:30PM - 9:30PM Keynote Session Room: Mesa A-B Speaker 2 of 4 Michael J. Detke, MedAvante Research Institute, USA New Treatments for Pain: Starting with the End in Mind – Market, Regulatory, and Development Challenges, and How These Relate to Neurobiology
Sunday, February 22 \| 7:30PM - 9:30PM Keynote Session Room: Mesa A-B Speaker 3 of 4 Xinzhong Dong, Johns Hopkins University, USA Short Talk: Regulation of TRP Channels by Pirt
Sunday, February 22 \| 7:30PM - 9:30PM Keynote Session Room: Mesa A-B Speaker 4 of 4 Samer Eid, Merck & Co., Inc., USA Short Talk: To Feel or not to Feel - Targeting the Heat Sensor TRPV1 for Pain Treatment
Monday, February 23 \| 7:00AM - 8:00AM Breakfast Room: Chamisa
Monday, February 23 \| 8:00AM - 11:00AM Nociceptor Transduction and Plasticity Room: Mesa A-B Speaker 1 of 5 * Ardem Patapoutian, The Scripps Research Institute, USA
Monday, February 23 \| 8:00AM - 11:00AM Nociceptor Transduction and Plasticity Room: Mesa A-B Speaker 2 of 5 Jon Levine, University of California, San Francisco, USA Kinases - Nociceptors Pain Switches
Monday, February 23 \| 8:00AM - 11:00AM Nociceptor Transduction and Plasticity Room: Mesa A-B Speaker 3 of 5 Peter McNaughton, Kings College London, UK Sensitization in Nociceptors
Monday, February 23 \| 8:00AM - 11:00AM Nociceptor Transduction and Plasticity Room: Mesa A-B Speaker 4 of 5 David Shelton, USA NGF and Anti-NGF: The Ying and Yang of Pain
Monday, February 23 \| 8:00AM - 11:00AM Nociceptor Transduction and Plasticity Room: Mesa A-B Speaker 5 of 5 Stephen B. McMahon, King's College London, UK Nociceptor Mechano-Sensitisation Induced by UVB Irradiation in Human and Rodent Skin
Monday, February 23 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Monday, February 23 \| 11:00AM - 11:00AM On Own for Lunch
Monday, February 23 \| 11:00AM - 1:00PM Poster Setup Room: Mesa C
Monday, February 23 \| 1:00PM - 10:00PM Poster Viewing Room: Mesa C
Monday, February 23 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Monday, February 23 \| 5:00PM - 7:00PM TRP Channels Room: Mesa A-B Speaker 1 of 5 * Stephen B. McMahon, King's College London, UK
Monday, February 23 \| 5:00PM - 7:00PM TRP Channels Room: Mesa A-B Speaker 2 of 5 Ardem Patapoutian, The Scripps Research Institute, USA Molecular Mechanisms of Thermosensation
Monday, February 23 \| 5:00PM - 7:00PM TRP Channels Room: Mesa A-B Speaker 3 of 5 David Julius, University of California, San Francisco, USA From Peppers to Peppermints: Natural Products as Probes of the Pain Pathway
Monday, February 23 \| 5:00PM - 7:00PM TRP Channels Room: Mesa A-B Speaker 4 of 5 Magdalene Moran, Hydra Biosciences, USA TRPs as Analgesic Drug Targets
Monday, February 23 \| 5:00PM - 7:00PM TRP Channels Room: Mesa A-B Speaker 5 of 5 Cheryl L. Stucky, Medical College of Wisconsin, USA Short Talk: TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons via Neuronal and Keratinocyte Expression
Monday, February 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Chamisa
Monday, February 23 \| 7:30PM - 10:00PM Poster Session 1 Room: Mesa C
Tuesday, February 24 \| 7:00AM - 8:00AM Breakfast Room: Chamisa
Tuesday, February 24 \| 8:00AM - 11:00AM Synaptic Plasticity Room: Mesa A-B Speaker 1 of 5 * David Julius, University of California, San Francisco, USA
Tuesday, February 24 \| 8:00AM - 11:00AM Synaptic Plasticity Room: Mesa A-B Speaker 2 of 5 Robert W. Gereau, Washington University Pain Center, USA Postsynaptic Mechanisms of Plasticity in Dorsal Horn Neurons
Tuesday, February 24 \| 8:00AM - 11:00AM Synaptic Plasticity Room: Mesa A-B Speaker 3 of 5 Sandra Garraway, Texas A & M, USA Activation of Neuronal ERK2 is Required for Inflammation-Induced Pain
Tuesday, February 24 \| 8:00AM - 11:00AM Synaptic Plasticity Room: Mesa A-B Speaker 4 of 5 Frank Porreca, University of Arizona, USA Modulating Descending Modulation
Tuesday, February 24 \| 8:00AM - 11:00AM Synaptic Plasticity Room: Mesa A-B Speaker 5 of 5 Hans Ulrich Zeilhofer, University of Zurich, Switzerland GABA-A Receptor Subunit-Specific Analgesia
Tuesday, February 24 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Tuesday, February 24 \| 11:00AM - 11:00AM On Own for Lunch
Tuesday, February 24 \| 11:00AM - 1:00PM Poster Setup Room: Mesa C
Tuesday, February 24 \| 1:00PM - 10:00PM Poster Viewing Room: Mesa C
Tuesday, February 24 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Tuesday, February 24 \| 5:00PM - 7:00PM Sodium and Calcium Channels Room: Mesa A-B Speaker 1 of 5 * Prisca Honore, Abbott Bioresearch Center, USA
Tuesday, February 24 \| 5:00PM - 7:00PM Sodium and Calcium Channels Room: Mesa A-B Speaker 2 of 5 Peter W. Reeh, University of Erlangen - Nurnberg, Germany Nociceptor Sodium Channels – Few but Decisive
Tuesday, February 24 \| 5:00PM - 7:00PM Sodium and Calcium Channels Room: Mesa A-B Speaker 3 of 5 Alex Binshtok, Harvard Medical School, USA Interleukin 1beta and Sodium Channels - From Slow Inactivation to Fast Nociception
Tuesday, February 24 \| 5:00PM - 7:00PM Sodium and Calcium Channels Room: Mesa A-B Speaker 4 of 5 Diane Lipscombe, Brown University, USA Nociceptors Modulate Calcium Channel Activity by Alternative Splicing.
Tuesday, February 24 \| 5:00PM - 7:00PM Sodium and Calcium Channels Room: Mesa A-B Speaker 5 of 5 Sarah E. Canetta, Columbia University, USA Short Talk: Type III Nrg1-erbB Signaling Affects Peripheral Nociception
Tuesday, February 24 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Chamisa
Tuesday, February 24 \| 7:30PM - 10:00PM Poster Session 2 Room: Mesa C
Wednesday, February 25 \| 7:00AM - 8:00AM Breakfast Room: Chamisa
Wednesday, February 25 \| 8:00AM - 11:00AM Discovering Pain Targets Room: Mesa A-B Speaker 1 of 5 * Simon Tate, GlaxoSmithKline, UK
Wednesday, February 25 \| 8:00AM - 11:00AM Discovering Pain Targets Room: Mesa A-B Speaker 2 of 5 Clifford J. Woolf, Children's Hospital, USA Finding Novel Analgesic Targets
Wednesday, February 25 \| 8:00AM - 11:00AM Discovering Pain Targets Room: Mesa A-B Speaker 3 of 5 Qiufu Ma, Dana Farber Cancer Institute, USA Regulation of Nociceptor Phenotype and Pain Behavior
Wednesday, February 25 \| 8:00AM - 11:00AM Discovering Pain Targets Room: Mesa A-B Speaker 4 of 5 Benjamin F. Cravatt III, The Scripps Research Institute, USA Modulating Pain by Blockade of Endocannabinoid Metabolism
Wednesday, February 25 \| 8:00AM - 11:00AM Discovering Pain Targets Room: Mesa A-B Speaker 5 of 5 Gary R. Lewin, Max Delbrück Center for Molecular Medicine, Germany Mechanostransducers as Targets for Pain Therapy
Wednesday, February 25 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Wednesday, February 25 \| 11:00AM - 11:00AM On Own for Lunch
Wednesday, February 25 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Wednesday, February 25 \| 5:00PM - 7:00PM Pain Circuits Room: Mesa A-B Speaker 1 of 5 * Gary R. Lewin, Max Delbrück Center for Molecular Medicine, Germany
Wednesday, February 25 \| 5:00PM - 7:00PM Pain Circuits Room: Mesa A-B Speaker 2 of 5 Mark Zylka, University of North Carolina, USA Biochemical Modulation of Nociceptive Circuits
Wednesday, February 25 \| 5:00PM - 7:00PM Pain Circuits Room: Mesa A-B Speaker 3 of 5 Allan I. Basbaum, University of California, San Francisco, USA Behaviorally Relevant Specificity of Nociceptors and Their Differential Regulation via mu and delta Opioid Receptors
Wednesday, February 25 \| 5:00PM - 7:00PM Pain Circuits Room: Mesa A-B Speaker 4 of 5 Joyce A. DeLeo, Dartmouth Medical School, USA Glial-Neuronal Circuits
Wednesday, February 25 \| 5:00PM - 7:00PM Pain Circuits Room: Mesa A-B Speaker 5 of 5 Sarah Ross, University of Pittsburgh, USA Short Talk: Bhlhb5 Is Critical for the Formation of Nociceptive Circuits in the Developing Spinal Cord
Wednesday, February 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Chamisa
Thursday, February 26 \| 7:00AM - 8:00AM Breakfast Room: Chamisa
Thursday, February 26 \| 8:00AM - 11:00AM Validating Pain Targets and Developing Analgesics Room: Mesa A-B Speaker 1 of 5 * Allan I. Basbaum, University of California, San Francisco, USA
Thursday, February 26 \| 8:00AM - 11:00AM Validating Pain Targets and Developing Analgesics Room: Mesa A-B Speaker 2 of 5 Simon Tate, GlaxoSmithKline, UK Progressing Pain Targets: A Focus on in vitro Screening
Thursday, February 26 \| 8:00AM - 11:00AM Validating Pain Targets and Developing Analgesics Room: Mesa A-B Speaker 3 of 5 Rohini Kuner, University of Heidelberg, Germany Target Validation using Genetically Modified Mice
Thursday, February 26 \| 8:00AM - 11:00AM Validating Pain Targets and Developing Analgesics Room: Mesa A-B Speaker 4 of 5 Prisca Honore, Abbott Bioresearch Center, USA Pharmacological Validation for Analgesia Targets
Thursday, February 26 \| 8:00AM - 11:00AM Validating Pain Targets and Developing Analgesics Room: Mesa A-B Speaker 5 of 5 Kenneth M. Verburg, Pfizer Inc., USA Pain Therapeutics: Focus on Development
Thursday, February 26 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Thursday, February 26 \| 11:00AM - 11:00AM On Own for Lunch
Thursday, February 26 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Thursday, February 26 \| 5:00PM - 7:00PM Pain Genetics Room: Mesa A-B Speaker 1 of 6 * Peter W. Reeh, University of Erlangen - Nurnberg, Germany
Thursday, February 26 \| 5:00PM - 7:00PM Pain Genetics Room: Mesa A-B Speaker 2 of 6 Annemieke Kavelaars, University of Texas MD Anderson Cancer Center, USA Short Talk: GRK2 Deficiency Prolongs PGE2-Induced Hyperalgesia via a Switch in Signaling from PKA to ERK
Thursday, February 26 \| 5:00PM - 7:00PM Pain Genetics Room: Mesa A-B Speaker 3 of 6 Michele Hummel, Wyeth Research, USA Short Talk: Corticotropin Releasing Factor1 Receptors Mediate Inflammatory- and Neuropathic-Like Pain
Thursday, February 26 \| 5:00PM - 7:00PM Pain Genetics Room: Mesa A-B Speaker 4 of 6 Achim Schmidtko, Goethe University, Germany Short Talk: Reduced Inflammatory and Neuropathic Pain in Mice Lacking Nitric Oxide-Sensitive Guanylyl Cyclase
Thursday, February 26 \| 5:00PM - 7:00PM Pain Genetics Room: Mesa A-B Speaker 5 of 6 Jeff S. Mogil, McGill University, Canada Genetics of Pain in the Laboratory Mouse
Thursday, February 26 \| 5:00PM - 7:00PM Pain Genetics Room: Mesa A-B Speaker 6 of 6 Luda Diatchenko, University of North Carolina School of Dentistry, USA Expansion of the Human mu-Opioid Receptor Gene Locus: Novel Functional Variants
Thursday, February 26 \| 7:00PM - 7:15PM Concluding Remarks Room: Mesa A-B Speaker 1 of 3 Clifford J. Woolf, Children's Hospital, USA
Thursday, February 26 \| 7:00PM - 7:15PM Concluding Remarks Room: Mesa A-B Speaker 2 of 3 Simon Tate, GlaxoSmithKline, UK
Thursday, February 26 \| 7:00PM - 7:15PM Concluding Remarks Room: Mesa A-B Speaker 3 of 3 Ardem Patapoutian, The Scripps Research Institute, USA
Thursday, February 26 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mesa A-B
Thursday, February 26 \| 8:00PM - 11:00PM Entertainment Room: Mesa A-B
Thursday, February 26 \| 8:00PM - 11:00PM Cash Bar Room: Mesa A-B
Friday, February 27 \| 10:25AM - 10:25AM Departure *Session Chair.