Web Desc
Fibrosis
joint with Allergy and Asthma
Organizer(s): John Varga, Thomas A. Wynn and Shelia Violette
Date: January 20 - 25, 2009
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Genzyme Corporation
For important information on the coronavirus, please click here
Summary of Meeting:
Fibrosis is a major cause of morbidity worldwide, can affect nearly all tissues, and is a dominant feature of diseases ranging from pulmonary fibrosis to glomerulosclerosis and cancer. Current treatments targeting the inflammatory cascade are ineffective in fibrosis. On-going research focuses on the role of innate immunity, and intrinsic mesenchymal cell alterations, plasticity, and progenitor cell differentiation in the pathogenesis. Experimental models, genetics and functional genomics have uncovered novel aspects of fibrosis, and innovative therapies are entering clinical trials. However, consensus on robust outcome measures or appropriate biomarkers for evaluating therapeutic effectiveness is lacking. This meeting brings together academic clinicians, researchers and pharmaceutical industry representatives from a variety of fields (1) to identify themes shared among the different fibrosing disorders, (2) to delineate promising novel molecular and cellular targets and treatment strategies, and (3) to discuss outcome measures and biomarkers for clinical trials. Opportunities for interdisciplinary interactions will be further enhanced by the concurrent meeting “Allergy and Asthma”, which will share a session with this meeting.
Scholarship Deadline: September 22 2008
Discounted Abstract Deadline: September 22 2008
Abstract Deadline: October 22 2008
Discounted Registration Deadline: November 20 2008
We gratefully acknowledge additional support for this conference from:
Genzyme CorporationStromedix, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genzyme Corporation

KineMed, Inc.

Promedior, Inc.

Stromedix, Inc.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, January 20 | 3:00PM - 7:30PM
Registration
Room: Longs Peak Foyer


Tuesday, January 20 | 6:30PM - 7:30PM
Refreshments
Room: Longs Peak Foyer


Tuesday, January 20 | 7:30PM - 8:30PM
Keynote Address
Room: Longs Peak

Speaker 1 of 1
Harry (Hal) C. Dietz, Johns Hopkins University School of Medicine, Blade Therapeutics, USA
TGF-beta, Microfibrils and Connective Tissue Homeostasis

Wednesday, January 21 | 7:00AM - 8:00AM
Breakfast
Room: Quandary 1-3


Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 1 of 7
* Moises Selman, Instituto Nacional de Enfermedades Respiratorias, Mexico

Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 2 of 7
David A. Schwartz, University of Colorado Denver, USA
Common Variants of MUC5AC and Pulmonary Fibrosis

Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 3 of 7
Richard P. Phipps, University of Rochester, USA
Fibroblast Heterogeneity –Impact of Fibroblast Diversity and Differentiation

Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 4 of 7
Harold A. Chapman, University of California, San Francisco, USA
Regulation of EMT and Pulmonary Fibrosis by Epithelial Integrins

Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 5 of 7
Manuela Funke, Massachusetts General Hospital, USA
Short Talk: Lysophosphatidic Acid Contributes to an Apoptosis Paradox in Lung Fibrosis

Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 6 of 7
Boris Hinz, University of Toronto, Canada
Myofibroblasts and Mechanical Signal Transduction

Wednesday, January 21 | 8:00AM - 11:15AM
Cellular Basis of Fibrosis: Focus on the Lung
Room: Longs Peak

Speaker 7 of 7
Usamah S. Kayyali, Tufts Medical Center, USA
Short Talk: MK2 Signaling in Fibroblast Biology and Pulmonary Fibrosis

Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 7
* Catherine M. Hawrylowicz, King's College London, UK


Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 7
Marsha Wills-Karp, Johns Hopkins Bloomberg School of Public Health, USA
Innate Immune Responses To Allergens


Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 7
Patrick G. Holt, University of Western Australia, Australia
Early Life Events that Influence Allergic Status


Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 7
René Teich, Philipps University of Marburg, Germany
Short Talk: Epigenetic Regulation of Asthma Protection Early in Life by the Non-Pathogenic Microbe Acinetobacter lwoffii F78


Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 7
* Scott T. Weiss, Brigham and Women's Hospital, USA
Vitamin D and Allergy/Asthma Prevalence


Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 6 of 7
David B. Lewis, Stanford University, USA
Influence of viral infections on the development of asthma: Insights from a murine model of influenza A viral-induced allergen sensitization for allergic pathogenesis and its prevention by vaccination for influenza


Wednesday, January 21 | 8:00AM - 11:15AM
Risk Factors, Early Life Events and Innate Mechanisms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 7 of 7
Matthew E. Poynter, University of Vermont, USA
Short Talk: Airway Epithelial Activation of NF-kappaB is Sufficient to Promote Allergic Sensitization to an Innocuous Inhaled Antigen


Wednesday, January 21 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, January 21 | 11:15AM - 11:15AM
On Own for Lunch


Wednesday, January 21 | 11:15AM - 1:00PM
Poster Setup
Room: Quandary 1-3


Wednesday, January 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary 1-3


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 1 of 9
* Richard H. Gomer, Texas A&M University, USA

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 2 of 9
* Robert Lafyatis, University of Pittsburgh Medical Center, USA

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 3 of 9
Brandi Nicole Baird, MD Anderson Cancer Center, Houston, TX, USA
Identification and Characterization of Prospectively Isolated Candidate Stem/Progenitor Cells in the Adult Mouse Lung

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 4 of 9
Marianne E. Fairclough, University of Birmingham, UK
Diversity within Monocyte Derived Stromal Cells

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 5 of 9
Darrell Pilling, Texas A&M University, USA
Th-1 Cytokines Inhibit, and Th-2 Cytokines Promote Fibrocyte Differentiation

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 6 of 9
Kirkwood A. Pritchard Jr., Medical College of Wisconsin, USA
The Role of Matrix and Mesenchymal Transition in Fibrosis in Tight Skin Mice

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 7 of 9
Peter H. S. Sporn, Northwestern University Feinberg School of Medicine, USA
Epithelial-Mesenchymal Transition in Normal Human Bronchial Epithelial Cells Triggered by TGF-beta1, Eosinophils and Cyclic Mechanical Strain

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 8 of 9
Shangxi Liu, University of Western Ontario, Canada
Loss of Beta 1 Integrin in Mouse Fibroblasts Results in Resistance to a bleo model of Skin Sclerodermav

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: EMT, Plasticity and the Origin of Fibroblasts
Room: Longs Peak

Speaker 9 of 9
Gregory deHart, FibroGen, Inc., USA
Regulation of Epithelial to Mesenchymal Transition by Connective Tissue Growth Factor

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 8
* Marsha Wills-Karp, Johns Hopkins Bloomberg School of Public Health, USA


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 8
* Donata Vercelli, University of Arizona, USA
Epigenetic Signatures of Environmental Exposures


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 8
Ulus Atasoy, University of Michigan, USA
Coordinate Posttranscriptional Regulation of Asthma Genes by the RNA Binding Protein HuR


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 8
Annerose Berndt, University of Pittsburgh Medical Center, USA
Haplotype Association Mapping for Airway Hyper-responsiveness and a Systematic Gene-identification Approach Identifies SERPINB6b


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 8
Jennifer Kearley, MedImmune, USA
Chitinase-like Protein BRP-39 is a Critical Mediator of Allergic Sensitization


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 6 of 8
Benjamin D. Medoff, Massachusetts General Hospital, USA
Adiponectin-Deficiency Increases Allergic Airway Inflammation and Pulmonary Vascular Remodeling


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 7 of 8
Lisa Cameron, University of Alberta, Canada
CRTh2+1431G>C is Associated with sIgE to Food Allergens and Allele-specific Transcription Factor Binding


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Genes and Gene: Environment Interactions and Inn
ate Immunity
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 8 of 8
Sean Saunders, Trinity Institute of Biomedical Sciences, Ireland
Talk Title to be Announced


Wednesday, January 21 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, January 21 | 5:00PM - 7:00PM
Liver Fibrosis
Room: Longs Peak

Speaker 1 of 5
* Thomas A. Wynn, Pfizer, USA

Wednesday, January 21 | 5:00PM - 7:00PM
Liver Fibrosis
Room: Longs Peak

Speaker 2 of 5
Anna Mae Diehl, Duke University, USA
The Cellular Biology and Clinical Spectrum of Liver Fibrosis

Wednesday, January 21 | 5:00PM - 7:00PM
Liver Fibrosis
Room: Longs Peak

Speaker 3 of 5
John P. Iredale, University of Bristol, UK
Liver Fibrosis: A Dynamic Model of Inflammation and Repair

Wednesday, January 21 | 5:00PM - 7:00PM
Liver Fibrosis
Room: Longs Peak

Speaker 4 of 5
Margaret M. Mentink-Kane, National Institute of Allergy and Infectious Diseases, National Institutes of Health, USA
Short Talk: Accelerated Liver Fibrosis in the Combined Absence of Interleukin-13 Regulatory Molecules: IL-13 Receptor Alpha 2, IL-10 and IL-12


Wednesday, January 21 | 5:00PM - 7:00PM
Liver Fibrosis
Room: Longs Peak

Speaker 5 of 5
Scott L. Friedman, Icahn School of Medicine at Mount Sinai, USA
Genetic Determinants of Fibrosis Progression

Wednesday, January 21 | 5:00PM - 7:00PM
Structural and Resident Cells of the Lung
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 5
* Stephen J. Galli, Stanford University, USA


Wednesday, January 21 | 5:00PM - 7:00PM
Structural and Resident Cells of the Lung
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 5
* Michael J. Holtzman, Washington University in St. Louis, USA
New Immune Pathways for Allergy and Asthma


Wednesday, January 21 | 5:00PM - 7:00PM
Structural and Resident Cells of the Lung
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 5
Hamida Hammad, Ghent University & VIB, Belgium
Short Talk: TLR4 Expression on Airway Stromal Cells is Crucial for Innate and Adaptive Immunity to House Dust Mite Allergen


Wednesday, January 21 | 5:00PM - 7:00PM
Structural and Resident Cells of the Lung
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 5
Maria do Carmo Leite-de-Moraes, CNRS, University Paris 5, France
NKT Cells in the Lung


Wednesday, January 21 | 5:00PM - 7:00PM
Structural and Resident Cells of the Lung
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 5
Steven F. Ziegler, Benaroya Research Institute, USA
TSLP and Allergic Inflammation


Wednesday, January 21 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary 1-3


Wednesday, January 21 | 7:30PM - 10:00PM
Poster Session 1
Room: Quandary 1-3


Thursday, January 22 | 7:00AM - 8:00AM
Breakfast
Room: Quandary 1-3


Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 1 of 7
* John Varga, Feinberg School of Medicine, USA

Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 2 of 7
Thomas A. Wynn, Pfizer, USA
Targets of IL-13 Signaling in Inflammation and Fibrosis

Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 3 of 7
Erica Herzog, Yale University School of Medicine, USA
Short Talk: Profibrotic Monocyte Subsets in Pulmonary Fibrosis

Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 4 of 7
Rebecca G. Wells, University of Pennsylvania, USA
Liver Fibrosis: The Intersection of Soluble and Mechanical Factors

Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 5 of 7
Paul W. Noble, Cedars-Sinai Medical Center, USA
Regulation and Lung Injury and Repair: Toll Like Receptors and Innate Immunity

Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 6 of 7
Anna P. Lam, Northwestern University, USA
Short Talk: Activated Canonical Wnt/beta-catenin Signaling Mediates Lung Fibroblast Migration and Proliferation

Thursday, January 22 | 8:00AM - 11:15AM
The Immunology and Cell Biology of Fibrosis
Room: Longs Peak

Speaker 7 of 7
Victor J. Thannickal, University of Alabama at Birmingham, USA
Apoptosis and Fibroblast Survival in Fibrogenesis

Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 7
* Bart N. Lambrecht, VIB, Ghent University, Belgium


Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 7
Sally Wenzel-Morganroth, University of Pittsburgh, USA
Asthma Phenotypes: Are we Closing the Loop to Pathobiology?


Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 7
Stephanie C. Eisenbarth, Yale University, USA
The Role of Inflammasomes in Vaccination and Allergic Disease


Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 7
Hiroshi Watarai, Riken Research Center for Allergy and Immunology, Japan
Short Talk: A novel Subset of Mouse NKT Cells Bearing the IL-17 Receptor B Responds to IL-25 and Contributes to Airway Hyperreactivity


Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 7
Frances E. Lund, University of Alabama at Birmingham, USA
CD38: Modulator of the NAD Metabolome and Regulator of Inflammation


Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 6 of 7
Pierre Bruhns, Institut Pasteur, France
Short Talk: FcgammaRIV as a Murine Equivalent of FcepsilonRI Expressed by Macrophages from Human Atopics in IgE-Induced inflammation


Thursday, January 22 | 8:00AM - 11:15AM
Effector Mechanisms and Cells
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 7 of 7
* K. Frank Austen, Harvard Medical School, USA
Leukotrienes as Therapeutic Targets in Asthma


Thursday, January 22 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, January 22 | 11:15AM - 11:15AM
On Own for Lunch


Thursday, January 22 | 11:15AM - 1:00PM
Poster Setup
Room: Quandary 1-3


Thursday, January 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary 1-3


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 1 of 8
* Andrew M. Tager, Massachusetts General Hospital, USA

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 2 of 8
* † John Westwick, Walden, UK

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 3 of 8
Shizhong Bu, Medical University of South Carolina, USA
DhS1P has a Potent Anti-Fibrotic Effect in Scleroderma Fibroblasts via Modulation of PTEN Levels

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 4 of 8
Enrique Brandan, P. Universidad Católica de Chile, Chile
Induction of Fibrosis by Exercise on Dystrophic Muscles: Role of CTGF

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 5 of 8
Tomoko Hayashida, Northwestern University, USA
Lack of beta1 Integrin Enhances TGF-beta Stimulated Type I Collagen Synthesis via Rac1 Mediated ERK Activity that Phosphorylates Smad Linker Region

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 6 of 8
Andreas Günther, University Hospital Giessen, Germany
Role of Defective Surfactant Processing and Transport in Hermansky-Pudlak-Syndrome Associated Interstitial Pneumonia (HPSIP) and Idiopathic Pulmonary Fibrosis (IPF)

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 7 of 8
Pura Muñoz Cánoves, Center for Genomic Regulation, Spain
Fibrin-Induced Inflammation Promotes Fibrosis in Muscular Dystrophy

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Model Systems for Studying Fibrosis
Room: Longs Peak

Speaker 8 of 8
Joe (Jia-hui) Wang, King's College London, UK
Antisense Inhibition of Kirsten-Ras Expression Reduces Fibrosis in a Rat Model of Unilateral Ureteric Obstruction

Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 10
* Bart N. Lambrecht, VIB, Ghent University, Belgium


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 10
* Paul B. Rothman, University of Iowa, USA


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 10
Charlotte Andreasen, Yale University, USA
TGF-beta1 Production by Alveolar Macrophages is Crucial for Controlling Inflammation in the Lung


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 10
Alison L. Budelsky, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Investigation of the Functional Roles for IL-17A, IL-25, IL-17RA, and IL-17RB in a Mouse Asthma Model


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 10
Jennifer Louten, Schering-Plough Biopharma, USA
IL-23 Signaling Negatively Regulates Th2 Responses in Asthma


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 6 of 10
Martijn C. Nawijn, University Medical Center Groningen, Netherlands
PAR2 Activation Induces Airways Hyperresponsiveness without Loss of Inhalation Tolerance


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 7 of 10
Mindy Tsai, Stanford University, USA
Thymic Stromal Lymphopoietin (TSLP) Promotes Myeloid Hyperplasia and Overproduction of Immunoglobulins, but not Skin Inflammation, in RabGEF1-deficient Mice


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 8 of 10
Nicolas Charles, INSERM U1149, France
Homeostatic Control of Basophil GATA-3 Expression and TH2 Differentiation by Lyn Kinase


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 9 of 10
Wanjun Chen, NIDCR, National Institutes of Health, USA
TGF-beta in the Development of CD4+ Foxp3+ Regulatory T Cells and the Regulation of House Dust Mite Induced Asthma


Thursday, January 22 | 2:30PM - 4:30PM
Workshop 2: Intercellular and Intracellular Signaling Mechan
isms
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 10 of 10
Nandini Krishnamoorthy, Brigham and Women's Hospital, Harvard Medical School, USA
A Critical Role for c-kit on Dendritic Cells in Regulating in T Helper Cell Differentiation and Allergic Asthma


Thursday, January 22 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, January 22 | 5:00PM - 7:15PM
Renal Fibrosis
Room: Longs Peak

Speaker 1 of 6
* Michael Zeisberg, Beth Israel Deaconess Medical Center and Harvard Medical School, USA

Thursday, January 22 | 5:00PM - 7:15PM
Renal Fibrosis
Room: Longs Peak

Speaker 2 of 6
Jeffrey B. Kopp, National Institutes of Health, USA
Overview of Renal Fibrosis

Thursday, January 22 | 5:00PM - 7:15PM
Renal Fibrosis
Room: Longs Peak

Speaker 3 of 6
Agnes Fogo, Vanderbilt University Medical Center, USA
Animal Models and the Reversibility of Fibrosis

Thursday, January 22 | 5:00PM - 7:15PM
Renal Fibrosis
Room: Longs Peak

Speaker 4 of 6
Jeremy S. Duffield, Vertex Pharmaceuticals, USA
Short Talk: Serum Amyloid P inhibits Renal Fibrosis through an Fc-gamma receptor dependent mechanism.

Thursday, January 22 | 5:00PM - 7:15PM
Renal Fibrosis
Room: Longs Peak

Speaker 5 of 6
H. William Schnaper, Northwestern University, USA
TGF-beta Signaling in Renal Fibrogenesis

Thursday, January 22 | 5:00PM - 7:15PM
Renal Fibrosis
Room: Longs Peak

Speaker 6 of 6
Jeremy S. Duffield, Vertex Pharmaceuticals, USA
Short Talk: Genetic Fate tracing reveal the stromal pericyte not EMT Generates Myofibroblasts in the Obstructive Model of Kidney Fibrosis

Thursday, January 22 | 5:00PM - 7:00PM
Immune Regulation
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 5
* Steven F. Ziegler, Benaroya Research Institute, USA


Thursday, January 22 | 5:00PM - 7:00PM
Immune Regulation
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 5
Valerie Julia, Galderma, Switzerland
Breast Milk-Mediated Transfer of an Antigen Induces Tolerance and Protection from Allergic Asthma


Thursday, January 22 | 5:00PM - 7:00PM
Immune Regulation
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 5
* Catherine M. Hawrylowicz, King's College London, UK
Regulatory T Cells in Allergy and Asthma: The Role of the Vitamin D Pathway


Thursday, January 22 | 5:00PM - 7:00PM
Immune Regulation
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 5
Yong-Jun Liu, Sanofi, USA
Cross Talk between Epithelial Cells and Dendritic Cells through TSLP/TSLPR in Allergic Inflamation


Thursday, January 22 | 5:00PM - 7:00PM
Immune Regulation
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 5
Hiromasa Inoue, Kagoshima University, Japan
Short Talk: Pulmonary SOCS1 as a Central Endogenous Inhibitor of Allergic Asthma


Thursday, January 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary 1-3


Thursday, January 22 | 7:30PM - 10:00PM
Poster Session 2
Room: Quandary 1-3


Friday, January 23 | 7:00AM - 8:00AM
Breakfast
Room: Quandary 1-3


Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 1 of 8
* Cory M. Hogaboam, Cedars-Sinai Medical Center, USA

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 2 of 8
Jack A. Elias, Yale School of Medicine, USA
Insights from Transgenic Models of Lung Fibrosis

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 3 of 8
James J. Lee, Mayo Clinic Scottsdale, USA
Eosinophils Orchestrate Allergic Pulmonary Responses: Who’s your Daddy Now T Cells!

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 4 of 8
John V. Fahy, University of California, San Francisco, USA
Short Talk: Plasma Proteins Inhibit Protease-Dependent Degradation of Airway Mucus Plugs in Acute Asthma

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 5 of 8
Hajime Karasuyama, Tokyo Medical and Dental University, Graduate School, Japan
Short Talk: Basophils Resolve Inflammation through Alternate Activation of Macrophages

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 6 of 8
Lauren E. Cohn, Yale University, USA
Short Talk: IFN-gamma Modulates Allergic Airway Disease through Effects on the Airway Epithelium

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 7 of 8
Jean Kim, Johns Hopkins University School of Medicine, USA
Short Talk: Involvement of VEGF in Upper Airway Epithelial Cell Dysfunction in Chronic Rhinosinusitis with Nasal Polyposis Subjects

Friday, January 23 | 8:00AM - 11:15AM
Asthma, Allergy and Tissue Remodeling (Joint)
Room: Longs Peak / Grays Peak

Speaker 8 of 8
Stephen J. Galli, Stanford University, USA
Mast Cells and Tissue Remodeling

Friday, January 23 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Friday, January 23 | 11:15AM - 11:15AM
On Own for Lunch


Friday, January 23 | 11:15AM - 1:00PM
Poster Setup
Room: Quandary 1-3


Friday, January 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary 1-3


Friday, January 23 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Friday, January 23 | 5:00PM - 7:15PM
Environmental Cues and Cellular Responses
Room: Longs Peak

Speaker 1 of 6
Rik Derynck, University of California, San Francisco, USA
TGF-beta Signaling and Epithelial to Mesenchymal Transition

Friday, January 23 | 5:00PM - 7:15PM
Environmental Cues and Cellular Responses
Room: Longs Peak

Speaker 2 of 6
Florian Rieder, Cleveland Clinic, USA
Short Talk: Endothelial-to-Mesenchymal Transition of Intestinal Mucosal Microvascular Cells: A Novel Mechanism of Intestinal Fibrosis

Friday, January 23 | 5:00PM - 7:15PM
Environmental Cues and Cellular Responses
Room: Longs Peak

Speaker 3 of 6
Andrew D. Luster, Massachusetts General Hospital, USA
Inflammation and Fibrosis - Chemokines, LPA

Friday, January 23 | 5:00PM - 7:15PM
Environmental Cues and Cellular Responses
Room: Longs Peak

Speaker 4 of 6
Andrew M. Tager, Massachusetts General Hospital, USA
Grease on the Fire: Chemokine- Lipid cooperation in Fibrosis

Friday, January 23 | 5:00PM - 7:15PM
Environmental Cues and Cellular Responses
Room: Longs Peak

Speaker 5 of 6
* Luisa A. DiPietro, University of Illinois at Chicago, USA
Scar Formation in the Healing Wound

Friday, January 23 | 5:00PM - 7:15PM
Environmental Cues and Cellular Responses
Room: Longs Peak

Speaker 6 of 6
Keith C. Olsen, University of Rochester, USA
Short Talk: Tissue Transglutaminase as a Novel Modulator of and Potential Therapeutic Target in Pulmonary Fibrosis

Friday, January 23 | 5:00PM - 7:00PM
Lipid Mediators, Proteases and Cytokines in Tissue Remodelin
g
This session is from Allergy and Asthma

Room: Grays 1-3

Speaker 1 of 5
* Joshua A. Boyce, Brigham and Women's Hospital, Harvard Medical School, USA


Friday, January 23 | 5:00PM - 7:00PM
Lipid Mediators, Proteases and Cytokines in Tissue Remodelin
g
This session is from Allergy and Asthma

Room: Grays 1-3

Speaker 2 of 5
Clare M. Lloyd, Imperial College London, UK
Cytokine Regulation of Allergic Airway Inflammation and Remodeling


Friday, January 23 | 5:00PM - 7:00PM
Lipid Mediators, Proteases and Cytokines in Tissue Remodelin
g
This session is from Allergy and Asthma

Room: Grays 1-3

Speaker 3 of 5
* Juan Rivera, USA
Sphingosine-1-Phosphate in Allergy and Asthma


Friday, January 23 | 5:00PM - 7:00PM
Lipid Mediators, Proteases and Cytokines in Tissue Remodelin
g
This session is from Allergy and Asthma

Room: Grays 1-3

Speaker 4 of 5
Gunnar Pejler, Swedish University of Agricultural Sciences, Sweden
Mast Cell Chymase - A Friend or Foe?


Friday, January 23 | 5:00PM - 7:00PM
Lipid Mediators, Proteases and Cytokines in Tissue Remodelin
g
This session is from Allergy and Asthma

Room: Grays 1-3

Speaker 5 of 5
Cara MM Williams, Wyeth Pharmaceuticals, USA
Short Talk: Cytosolic Phospholipase A2alpha Orchestrates Allergic Disease


Friday, January 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary 1-3


Friday, January 23 | 7:30PM - 10:00PM
Poster Session 3
Room: Quandary 1-3


Saturday, January 24 | 7:00AM - 8:00AM
Breakfast
Room: Quandary 1-3


Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 1 of 7
* Michael Gilman, Arrakis Therapeutics, USA

Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 2 of 7
Howard Y. Chang, Stanford University, USA
Genomic Encoding of Fibroblast Positional Identities: Implications for Fibrosis

Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 3 of 7
Roland M. duBois, National Jewish Health, USA
Genetics of Diffuse Lung Fibrosis: Lessons Learned

Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 4 of 7
Shelia M. Violette, Q32 Bio, USA
Therapeutic Potential of a Function Blocking alphavbeta6 Antibody in Fibrosis and Oncology: Transition from Research to Clinic Development


Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 5 of 7
Scott M. Lonning, Cell Signaling Technology, USA
Prospects and Challenges of TGFbeta Neutralization for the Treatment of Pathologic Fibrosis


Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 6 of 7
Francesco Del Galdo, Thomas Jefferson University, USA
Short Talk: Quantitative Assessment of Tissue Fibrosis in Skin Biopsies from Patients with Systemic Sclerosis Employing Confocal Laser Scanning Microscopy (CLSM). An Objective Outcome Measure for Clinical Trials

Saturday, January 24 | 8:00AM - 11:15AM
Novel Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 7 of 7
Kusum V. Pandit, University of Pittsburgh, USA
Short Talk: MicroRNAs in Lung Fibrosis

Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 7
* Edith M. Hessel, Dynavax Technologies, USA


Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 7
John A. Cidlowski, NIEHS, National Institutes of Health, USA
The Glucocorticoid Receptor: One Gene, Many Proteins – New Mechanisms for Tissue Specific Anti-Inflammatory Actions of Glucocorticoids in Health and Disease.


Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 7
Marco Conti, University of California, San Francisco, USA
Cyclic AMP-Specific Phosphodiesterase Regulation as a Critical Component of the Airway Inflammatory Responses


Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 7
Joshua A. Boyce, Brigham and Women's Hospital, Harvard Medical School, USA
Short Talk: Leukotriene E4-Induced Pulmonary Inflammation is Mediated by the P2Y12 Receptor


Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 7
Heidi Campos Schilter, Pharmaxis, Australia
Short Talk: A Role for Fatty Acid Binding Proteins in Airway Immune Responses


Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 6 of 7
Prescott G. Woodruff, University of California, San Francisco, USA
Short Talk: Presence or Absence of IL-13-Driven Inflammation Defines Major Sub-Phenotypes of Asthma


Saturday, January 24 | 8:00AM - 11:00AM
Conventional and Novel Targets for Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 7 of 7
Monika Vig, Washington University School of Medicine, USA
CRACM1, a Potential Target for Inhibition of Allergic and Inflammatory Disorders


Saturday, January 24 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Saturday, January 24 | 11:15AM - 11:15AM
On Own for Lunch


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 1 of 9
* Shelia M. Violette, Q32 Bio, USA

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 2 of 9
April A. Cox, Array Biopharma, USA
Preclinical Efficacy of a PDGFR inhibitor, ARRY-768, in a Rat Model of Gadolinium-Induced Fibrosis

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 3 of 9
Francesco Del Galdo, Thomas Jefferson University, USA
A Pattern of Shared Alterations in the Secretome of Dermal Fibroblasts from Systemic Sclerosis and Nephrogenic Systemic Fibrosis: A Biomarker Signature for Fibrotic Diseases

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 4 of 9
Qihe Xu, King's College London School of Medicine, UK
Discovery of Herbal Compounds with in vitro Anti-Fibrotic Activities

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 5 of 9
Jadranka Milosevic, Simmons Center for Interstitial Lung Disease, USA
The Role of miR-154 microRNA Family in IPF

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 6 of 9
Jennifer L. Sargent, Dartmouth Medical School, USA
Overlapping and Distinct Gene Targets of TGFbeta, IL13 and IL4 in Dermal Fibroblasts are Expressed in Distinct Molecular Subsets of Systemic Sclerosis

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 7 of 9
Timothy W. Schacker, University of Minnesota, USA
Lymph Node Fibrosis Is A Significant Factor In HIV Pathogenesis And Limits Immune Reconstitution Despite Antiretroviral Therapy Suppression of Viral Replication

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 8 of 9
Oscar O. Braun, University of California San Diego, USA
Cyclic AMP can Both Block and Reverse the Fibrotic Phenotype of Cardiac Fibroblasts

Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Therapeutic Targets and Biomarkers
Room: Longs Peak

Speaker 9 of 9
Guofei Zhou, Northwestern University, USA
Elevated von Hippel-Lindau Protein Expression in Fibrotic Lungs and Its Role in Fibrogenesis


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 9
* Stephen J. Galli, Stanford University, USA


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 9
Helen E. Harries, UK
Local Clonal Expansion of IgE Producing B Cells


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 9
Yuzaburo Inoue, Graduate School of Medicine, Chiba University, Japan
Chitinase Family Members Inhibit House Dust Mite-Induced AHR Independently of Enzymatic Activity


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 9
Irene H. Heijink, University Medical Center Groningen, Netherlands
House Dust Mite-Promoted Epithelial-to-Mesenchymal Transition in Human Bronchial Epithelium


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 9
Sara Wernersson, Swedish University of Agricultural Sciences, Sweden
Protective Role of mMCP-4 in Allergic Inflammation


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 6 of 9
Mayumi Ueta, Kyoto Prefectural University of Medicine, Japan
PGE Receptor Subtype EP3 Regulates LPR of Allergic Conjunctivitis


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 7 of 9
Karin Stebbins, Amira Pharmaceuticals, USA
Novel DP2 Receptor Antagonist Decreases Allergic Inflammation


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 8 of 9
Anton J.M. van Oosterhout, GSK R&D, UK
IL-10 Producing CD11c+ Cells in SIT in Mouse Model of Asthma


Saturday, January 24 | 2:30PM - 4:30PM
Workshop 3: Effector Cells and Mechanisms in Asthma
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 9 of 9
Joan M. Cook-Mills, Indiana University, USA
Isoforms of Vitamin E have Opposing Immunoregulatory Function in Allergic Inflammation


Saturday, January 24 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Saturday, January 24 | 5:00PM - 7:00PM
Novel Therapies
Room: Longs Peak

Speaker 1 of 5
* Scott M. Lonning, Cell Signaling Technology, USA

Saturday, January 24 | 5:00PM - 7:00PM
Novel Therapies
Room: Longs Peak

Speaker 2 of 5
Bruce Cronstein, New York University, USA
Venegeance is Mine. Adenosine, a Retaliatory Metabolite

Saturday, January 24 | 5:00PM - 7:00PM
Novel Therapies
Room: Longs Peak

Speaker 3 of 5
Mark L. Lupher, Jr., Muregen, LLC, USA
Regulating Fibrosis with the Natural Innate Response Modifier, SAP

Saturday, January 24 | 5:00PM - 7:00PM
Novel Therapies
Room: Longs Peak

Speaker 4 of 5
Claire Emson, Genentech, Inc., USA
Measurement of Collagen Synthesis by Heavy Water Labeling and its Application for Indentifying Anti-Fibrotic Therapies

Saturday, January 24 | 5:00PM - 7:00PM
Novel Therapies
Room: Longs Peak

Speaker 5 of 5
Ruchi Bansal, University of Twente, Netherlands
Short Talk: A Mimetic Peptide of Interferon gamma (IFNgamma) as a Novel Anti-Fibrotic Agent

Saturday, January 24 | 5:00PM - 7:00PM
Immune Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 1 of 5
* Yong-Jun Liu, Sanofi, USA


Saturday, January 24 | 5:00PM - 7:00PM
Immune Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 2 of 5
Edith M. Hessel, Dynavax Technologies, USA
Effects of TLR-9 Agonists in Asthma: Moving Towards Long-Lasting Disease Modification


Saturday, January 24 | 5:00PM - 7:00PM
Immune Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 3 of 5
Lawren C. Wu, Amgen Inc., USA
Short Talk: Reduction of Serum IgE by Depletion of the IgE B Cell Lineage – a Novel Approach for the Treatment of Allergic Diseases


Saturday, January 24 | 5:00PM - 7:00PM
Immune Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 4 of 5
Bart N. Lambrecht, VIB, Ghent University, Belgium
Targeting Dendritic Cells


Saturday, January 24 | 5:00PM - 7:00PM
Immune Intervention
This session is from Allergy and Asthma
Room: Grays 1-3

Speaker 5 of 5
* Anthony J. Coyle, Pfizer, USA
Cytokine Antagonists


Saturday, January 24 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary 1-3


Saturday, January 24 | 8:00PM - 11:00PM
Entertainment
Room: Quandary 1-3


Saturday, January 24 | 8:00PM - 11:00PM
Cash Bar
Room: Quandary 1-3


Sunday, January 25 | 10:22AM - 10:22AM
Departure


*Session Chair
†Invited, not yet responded.