Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Uncomplicating Diabetes: Reducing the Burden of Diabetes-Related End-Organ Injury (2018J7)
Complications of Diabetes (2014X7)
Complications of Diabetes: Mechanisms of Injury and Failure of Repair (2012C5)
Obesity (2011J2)
Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction (2011J1)

Web Desc
Complications of Diabetes and Obesity joint with Dissecting the Vasculature: Function, Molecular Mechanisms and Malfunction Organizer(s): Ann Marie Schmidt, George L. King and Thomas M. Coffman Date: February 24 - March 01, 2009 Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada Sponsored by Pfizer Global Research & Development Summary of Meeting: The complications of diabetes and obesity are emerging as major health problems in the United States and world-wide. Obesity-linked complications may lead to the development of insulin resistance and, ultimately, hyperglycemia. Thus, the study of mechanisms underlying and linking these disorders holds promise for the identification of mechanism-targeted therapeutic agents. In addition to frank and often destructive recruitment of immune responses, diabetes and obesity are significantly modified by host and environment factors. Such factors as hypertension, innate aging, failure of effective pro- or anti- angiogenesis programs, genetic and epigenetic factors may influence the phenotype and outcome in diabetes and obesity. The goals of the meeting will be to integrate these concepts in close collaboration with the “Dissecting the Vasculature” concurrent meeting group. Beginning with the vessel, and addressing superimposed and modifying factors, this program will facilitate greater understanding of mechanisms linked to diabetes and its complications and obesity. Scholarship Deadline: October 23 2008 Discounted Abstract Deadline: October 23 2008 Abstract Deadline: November 25 2008 Discounted Registration Deadline: December 29 2008 We gratefully acknowledge additional support for this conference from: We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 5R13DK076500-03 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Complications of Diabetes and Obesity

joint with Dissecting the Vasculature: Function, Molecular Mechanisms and Malfunction

Organizer(s): Ann Marie Schmidt, George L. King and Thomas M. Coffman

Date: February 24 - March 01, 2009
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada

Sponsored by Pfizer Global Research & Development

Summary of Meeting:

The complications of diabetes and obesity are emerging as major health problems in the United States and world-wide. Obesity-linked complications may lead to the development of insulin resistance and, ultimately, hyperglycemia. Thus, the study of mechanisms underlying and linking these disorders holds promise for the identification of mechanism-targeted therapeutic agents. In addition to frank and often destructive recruitment of immune responses, diabetes and obesity are significantly modified by host and environment factors. Such factors as hypertension, innate aging, failure of effective pro- or anti- angiogenesis programs, genetic and epigenetic factors may influence the phenotype and outcome in diabetes and obesity. The goals of the meeting will be to integrate these concepts in close collaboration with the “Dissecting the Vasculature” concurrent meeting group. Beginning with the vessel, and addressing superimposed and modifying factors, this program will facilitate greater understanding of mechanisms linked to diabetes and its complications and obesity.

Scholarship Deadline: October 23 2008

Discounted Abstract Deadline: October 23 2008

Abstract Deadline: November 25 2008

Discounted Registration Deadline: December 29 2008

We gratefully acknowledge additional support for this conference from:

Lilly Singapore Centre for Drug Discovery

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK076500-03

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Tuesday, February 24 \| 3:00PM - 7:30PM Registration Room: BC Foyer
Tuesday, February 24 \| 6:30PM - 7:30PM Refreshments Room: Pacific Ballroom
Tuesday, February 24 \| 7:30PM - 8:30PM Keynote Address (Joint) Room: British Columbia Ballroom Speaker 1 of 3 * William F. Jackson, Michigan State University, USA
Tuesday, February 24 \| 7:30PM - 8:30PM Keynote Address (Joint) Room: British Columbia Ballroom Speaker 2 of 3 * Ann Marie Schmidt, New York University Langone Medical Center, USA
Tuesday, February 24 \| 7:30PM - 8:30PM Keynote Address (Joint) Room: British Columbia Ballroom Speaker 3 of 3 Joseph Loscalzo, Brigham and Women's Hospital, Harvard Medical School, USA Redox Dysregulation in Vascular Disease
Wednesday, February 25 \| 7:00AM - 8:00AM Breakfast Room: Pacific Ballroom
Wednesday, February 25 \| 8:00AM - 11:15AM Glucose and Other Metabolites: Actions on Target Cells Room: Columbia Ballroom Speaker 1 of 6 * Michael A. Brownlee, Albert Einstein College of Medicine, USA Unifying Mechanisms and the Complications of Diabetes
Wednesday, February 25 \| 8:00AM - 11:15AM Glucose and Other Metabolites: Actions on Target Cells Room: Columbia Ballroom Speaker 2 of 6 Ann Marie Schmidt, New York University Langone Medical Center, USA RAGE, Inflammation and the Complications of Diabetes
Wednesday, February 25 \| 8:00AM - 11:15AM Glucose and Other Metabolites: Actions on Target Cells Room: Columbia Ballroom Speaker 3 of 6 George L. King, Joslin Diabetes Center, USA Protein Kinase C and the Complications of Diabetes
Wednesday, February 25 \| 8:00AM - 11:15AM Glucose and Other Metabolites: Actions on Target Cells Room: Columbia Ballroom Speaker 4 of 6 Adriana Machado-Lima, University of São Paulo, Brazil Short Talk: Glycated Albumin Isolated from Uncontrolled Type 1 and Type 2 Diabetes Mellitus Patients Impairs Cell Cholesterol Removal and Induces Lipid Accumulation in Macrophages
Wednesday, February 25 \| 8:00AM - 11:15AM Glucose and Other Metabolites: Actions on Target Cells Room: Columbia Ballroom Speaker 5 of 6 Paul Fernyhough, St Boniface Research Centre, Canada Mitochondrial Stress and the Pathogenesis of Diabetic Neuropathy
Wednesday, February 25 \| 8:00AM - 11:15AM Glucose and Other Metabolites: Actions on Target Cells Room: Columbia Ballroom Speaker 6 of 6 Bruce A. Perkins, University of Toronto, Canada Short Talk: Excess Urinary Excretion of Markers of Glycation Predict Subsequent Early Renal Function Decline in Type 1 Diabetes
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 1 of 8 * Jonathan H. Jaggar, University of Tennessee College of Medicine, USA
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 2 of 8 * Michel Feletou, Institut de Recherche Servier, France
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 3 of 8 Brant M. Weinstein, NICHD, National Institutes of Health, USA Regulation of Developmental Angiogenesis and Lymphangiogenesis
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 4 of 8 Mark S. Taylor, University of South Alabama College of Medicine, USA Localized Calcium Signaling in the Endothelium
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 5 of 8 Lothar A. Blatter, Rush University Chicago, USA Calcium and NFAT Signaling in Vascular Endothelial Cells
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 6 of 8 Luisa Iruela-Arispe, University of California, Los Angeles, USA Intracrine VEGF Signaling in Endothelial Cells
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 7 of 8 Ralf Koehler, Phillips University Marburg, Germany Short Talk: EDHF-Signaling and Arterial Blood Pressure in Mice Deficient of Endothelial KCa-Channels
Wednesday, February 25 \| 8:00AM - 11:00AM Endothelial Cell Signaling Components This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 8 of 8 Evgenia V. Gerasimovskaya, University of Colorado Denver, USA Short Talk: PI3K and RhoA/ROCK Pathways Play a Critical Role in Hypoxia-Induced ATP Exocytosis and ATP-induced Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells
Wednesday, February 25 \| 9:20AM - 9:40AM Coffee Break Room: BC Foyer
Wednesday, February 25 \| 11:15AM - 11:15AM On Own for Lunch
Wednesday, February 25 \| 11:15AM - 1:00PM Poster Setup Room: Pacific Ballroom
Wednesday, February 25 \| 1:00PM - 10:00PM Poster Viewing Room: Pacific Ballroom
Wednesday, February 25 \| 2:30PM - 4:30PM Workshop 1: Techniques (Joint) Room: British Columbia Ballroom Speaker 1 of 4 * Karen Lounsbury, University of Vermont, USA
Wednesday, February 25 \| 2:30PM - 4:30PM Workshop 1: Techniques (Joint) Room: British Columbia Ballroom Speaker 2 of 4 Paul L. Hermonat, University of Arkansas for Medical Sciences, USA Viral Gene Therapy Targeting the Vasculature
Wednesday, February 25 \| 2:30PM - 4:30PM Workshop 1: Techniques (Joint) Room: British Columbia Ballroom Speaker 3 of 4 W. Gil Wier, University of Maryland School of Medicine, USA Techniques for Imaging Signal Transduction in the Vasculature
Wednesday, February 25 \| 2:30PM - 4:30PM Workshop 1: Techniques (Joint) Room: British Columbia Ballroom Speaker 4 of 4 Lloyd P. Aiello, Joslin Diabetes Center, USA Designing Clinical Trials - The Fruits of Translational Research
Wednesday, February 25 \| 4:30PM - 5:00PM Coffee Available Room: BC Foyer
Wednesday, February 25 \| 5:00PM - 7:00PM Insulin Resistance and Actions Room: Columbia Ballroom Speaker 1 of 4 * C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA Insulin Actions and Cardiovascular Pathologies
Wednesday, February 25 \| 5:00PM - 7:00PM Insulin Resistance and Actions Room: Columbia Ballroom Speaker 2 of 4 Michael J. Quon, National Institutes of Health, USA Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction: From Cells to Humans
Wednesday, February 25 \| 5:00PM - 7:00PM Insulin Resistance and Actions Room: Columbia Ballroom Speaker 3 of 4 Nir Barzilai, Albert Einstein College of Medicine, USA Aging and Insulin Resistance
Wednesday, February 25 \| 5:00PM - 7:00PM Insulin Resistance and Actions Room: Columbia Ballroom Speaker 4 of 4 Manuel Roman Benito, Universidad de Complutense, Spain Short Talk: Compensated and Non-Compensated Insulin Resistance Induces Differential Cardiovascular Damage in Obese BATIRKO Mice
Wednesday, February 25 \| 5:00PM - 7:00PM Endothelial Cell Interactions and Targeting This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 1 of 6 * Mark S. Taylor, University of South Alabama College of Medicine, USA
Wednesday, February 25 \| 5:00PM - 7:00PM Endothelial Cell Interactions and Targeting This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 2 of 6 * Richard A. Cohen, Boston University School of Medicine, USA
Wednesday, February 25 \| 5:00PM - 7:00PM Endothelial Cell Interactions and Targeting This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 3 of 6 Sarah Y. Yuan, University of California, Davis, USA Endothelial Junction and Vascular Permeability
Wednesday, February 25 \| 5:00PM - 7:00PM Endothelial Cell Interactions and Targeting This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 4 of 6 Michel Feletou, Institut de Recherche Servier, France The Endothelium as a Target for Drug Development
Wednesday, February 25 \| 5:00PM - 7:00PM Endothelial Cell Interactions and Targeting This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 5 of 6 Wolfgang F. Graier, Medical University of Graz, Austria Endothelial Mitochondria as Key Players for Endothelial Cell Function and Dysfunction
Wednesday, February 25 \| 5:00PM - 7:00PM Endothelial Cell Interactions and Targeting This session is from Vasculature Room: British Ballroom The Endothelial Cell: New Molecules and Markers Speaker 6 of 6 Caroline Cheng, Erasmus Medical Center, Netherlands Short Talk: Functional Analysis of a Newly Identified Regulator of New Vessel Formation “EGIP”
Wednesday, February 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Pacific Ballroom
Wednesday, February 25 \| 7:30PM - 10:00PM Poster Session 1 Room: Pacific Ballroom
Thursday, February 26 \| 7:00AM - 8:00AM Breakfast Room: Pacific Ballroom
Thursday, February 26 \| 7:00AM - 8:00AM Poster Setup Room: Pacific Ballroom
Thursday, February 26 \| 8:00AM - 11:15AM Inflammation and Immunity: Links to Diabetes and Obesity Room: Columbia Ballroom Speaker 1 of 6 Anthony W. Ferrante, Columbia University, USA Inflammatory Mechanisms and Obesity
Thursday, February 26 \| 8:00AM - 11:15AM Inflammation and Immunity: Links to Diabetes and Obesity Room: Columbia Ballroom Speaker 2 of 6 Ajay Chawla, Merck Research Labs, USA Macrophage Activation, Obesity and Insulin Resistance
Thursday, February 26 \| 8:00AM - 11:15AM Inflammation and Immunity: Links to Diabetes and Obesity Room: Columbia Ballroom Speaker 3 of 6 * Douglas Golenbock, University of Massachusetts Medical School, USA Toll Like Receptors - Linking Innate and Adaptive Immunity
Thursday, February 26 \| 8:00AM - 11:15AM Inflammation and Immunity: Links to Diabetes and Obesity Room: Columbia Ballroom Speaker 4 of 6 Ishwarlal Jialal, University of California, Davis, USA Diabetes (both Type 1 & 2) is a Pro-Inflammatory State?
Thursday, February 26 \| 8:00AM - 11:15AM Inflammation and Immunity: Links to Diabetes and Obesity Room: Columbia Ballroom Speaker 5 of 6 Patricia W. Bedard, Pfizer, USA Short Talk: CX3CR1 Contributes to Adipose Tissue Macrophage Infiltration and Insulin Resistance on a High Fat, High Sucrose Diet
Thursday, February 26 \| 8:00AM - 11:15AM Inflammation and Immunity: Links to Diabetes and Obesity Room: Columbia Ballroom Speaker 6 of 6 Zhaoyun Zhang, Joslin Diabetes Center, USA Short Talk: Overexpressing G6PD Reduces Oxidant Stress Induced by High Glucose via PKA Activation in Endothelial Cells
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 1 of 8 * Julian H. Lombard, Medical College of Wisconsin, USA
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 2 of 8 * Keshari Thakali, Univ of Arkansas for Medical Sciences, USA
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 3 of 8 Mark W. Majesky, University of North Carolina at Chapel Hill, USA Developmental Origins of Coronary Smooth Muscle
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 4 of 8 Jonathan H. Jaggar, University of Tennessee College of Medicine, USA Mitochondrial Regulation of Arterial Calcium Signaling and Diameter
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 5 of 8 William F. Jackson, Michigan State University, USA Vascular Ion Channels: Will the Key Players Please Stand Up?
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 6 of 8 Karen Lounsbury, University of Vermont, USA Phenotype Switching in Vascular Smooth Muscle Cells: A Complex Interaction between Transcription Factors
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 7 of 8 Prasad V.G Katakam, Wake Forest University Health Sciences, USA Short Talk: Impaired Mitochondria Dependent Vasodilation in Cerebral Arteries of Zucker Obese Rats with Insulin Resistance
Thursday, February 26 \| 8:00AM - 11:15AM Vascular Smooth Muscle Cell Components and Communicators This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 8 of 8 Magdalena M. Szewczyk, McMaster University, Canada Short Talk: Inhibitors Bioengineered to Inhibit Different Isoforms of Plasma Membrane Ca2+ Pumps in Vascular Smooth Muscle and Endothelium
Thursday, February 26 \| 9:20AM - 9:40AM Coffee Break Room: BC Foyer
Thursday, February 26 \| 11:15AM - 12:00PM Lunch Room: Pacific Ballroom
Thursday, February 26 \| 12:00PM - 2:30PM Poster Session 2 Room: Pacific Ballroom
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 1 of 7 * Ann Marie Schmidt, New York University Langone Medical Center, USA
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 2 of 7 * Nancy J. Rusch, University of Arkansas for Medical Sciences, USA
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 3 of 7 Cristina Rabadan-Diehl, NHLBI, National Institutes of Health, USA
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 4 of 7 Ronald A. Kohanski, NIA, National Institutes of Health, USA
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 5 of 7 Teresa Jones, NIDDK, National Institutes of Health, USA
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 6 of 7 R. Clinton Webb, Georgia Regents University, USA
Thursday, February 26 \| 2:30PM - 4:30PM Workshop 2: Funding for the Young Cardiovascular and Diabete s Investigator (Joint) Room: British Columbia Ballroom Speaker 7 of 7 Barbara Araneo, Novo Nordisk, USA
Thursday, February 26 \| 4:30PM - 5:00PM Coffee Available Room: BC Foyer
Thursday, February 26 \| 5:00PM - 7:00PM Regeneration and Diabetes Room: Columbia Ballroom Speaker 1 of 4 Douglas Zochodne, University of Calgary, Canada Diabetes and Regenerative Failure of Peripheral Neurons
Thursday, February 26 \| 5:00PM - 7:00PM Regeneration and Diabetes Room: Columbia Ballroom Speaker 2 of 4 * Martin Friedlander, The Scripps Research Institute, USA Cell-Based Therapies for Diabetic Retinopathy
Thursday, February 26 \| 5:00PM - 7:00PM Regeneration and Diabetes Room: Columbia Ballroom Speaker 3 of 4 Omaida C. Velazquez, University of Miami, Jackson Memorial Hospital, USA The Potential Role of Hyperoxia and Endothelial Progenitor Cell Mobilization in Diabetic Wound Healing
Thursday, February 26 \| 5:00PM - 7:00PM Regeneration and Diabetes Room: Columbia Ballroom Speaker 4 of 4 Alex Chen, University of Pittsburgh, USA Short Talk: Restoration of Endothelial Progenitor Cell Function with Manganese Superoxide Dismutase Gene Transfer in Type 2 Diabetic Wound Healing
Thursday, February 26 \| 5:00PM - 7:00PM New Insights into Mechanisms of Vascular Contraction This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 1 of 6 * Frank Chip Brosius III, University of Michigan, USA
Thursday, February 26 \| 5:00PM - 7:00PM New Insights into Mechanisms of Vascular Contraction This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 2 of 6 * Lothar A. Blatter, Rush University Chicago, USA
Thursday, February 26 \| 5:00PM - 7:00PM New Insights into Mechanisms of Vascular Contraction This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 3 of 6 Richard J. Paul, University of Cincinnati College of Medicine, USA It’s Not Just [Ca2+]i Anymore or Rho, ROS and Hypoxic Vasorelaxation
Thursday, February 26 \| 5:00PM - 7:00PM New Insights into Mechanisms of Vascular Contraction This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 4 of 6 R. Clinton Webb, Georgia Regents University, USA New Insights into Mechanisms of Vascular Contraction: STIM-1/Orai-1 Pathway and Vascular Dysfunction
Thursday, February 26 \| 5:00PM - 7:00PM New Insights into Mechanisms of Vascular Contraction This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 5 of 6 W. Gil Wier, University of Maryland School of Medicine, USA Genetically Encoded FRET-Based Sensors Allow Visualization of Signal Transduction in Individual Cells of Intact Arteries
Thursday, February 26 \| 5:00PM - 7:00PM New Insights into Mechanisms of Vascular Contraction This session is from Vasculature Room: British Ballroom Vascular Smooth Muscle Cell Dissection: From Birth to Function Speaker 6 of 6 Zachary P. Neeb, Indiana University School of Medicine, USA Short Talk: Store-Operated Ca2+ Influx in Coronary Smooth Muscle Cells Predicts Coronary Atherosclerosis in the Metabolic Syndrome
Thursday, February 26 \| 7:00PM - 7:00PM On Own for Dinner
Friday, February 27 \| 7:00AM - 8:00AM Breakfast Room: Pacific Ballroom
Friday, February 27 \| 8:00AM - 11:15AM Novel Targets and Treatments for Diabetes and its Complicati ons Room: Columbia Ballroom Speaker 1 of 6 Lloyd P. Aiello, Joslin Diabetes Center, USA Novel Targets and Treatments for Diabetic Retinopathy and Macular Edema
Friday, February 27 \| 8:00AM - 11:15AM Novel Targets and Treatments for Diabetes and its Complicati ons Room: Columbia Ballroom Speaker 2 of 6 Kumar Sharma, USA A Systems Biology Understanding of Diabetic Nephropathy Based on Novel Anti-Fibrosis Treatments and Biomarkers
Friday, February 27 \| 8:00AM - 11:15AM Novel Targets and Treatments for Diabetes and its Complicati ons Room: Columbia Ballroom Speaker 3 of 6 * Ravichandran Ramasamy, New York University School of Medicine, USA Aldose Reductase & Rage: Key Targets for Cardioprotective Interventions in Diabetes
Friday, February 27 \| 8:00AM - 11:15AM Novel Targets and Treatments for Diabetes and its Complicati ons Room: Columbia Ballroom Speaker 4 of 6 Nobuyo Maeda, University of North Carolina, USA Antioxidant Defense against Diabetic Cardiovascular Disease
Friday, February 27 \| 8:00AM - 11:15AM Novel Targets and Treatments for Diabetes and its Complicati ons Room: Columbia Ballroom Speaker 5 of 6 Lokesh Kumar Bhatt, School of Pharmacy and Technology Management, India Short Talk: Enhancement of MMP2 and MMP9 Inhibition in Presence of Aspirin, a COX Inhibitor: A New Therapeutic Approach in Treatment of Diabetic Neuropathy
Friday, February 27 \| 8:00AM - 11:15AM Novel Targets and Treatments for Diabetes and its Complicati ons Room: Columbia Ballroom Speaker 6 of 6 Jia Liu, Joslin Diabetes Center, USA Short Talk: Plasma Kallikrein Exacerbates Intracerebral Hemorrhage Expansion in Diabetic Rats
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 1 of 8 * David Robertson, Vanderbilt University Medical Center, USA
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 2 of 8 * William F. Jackson, Michigan State University, USA
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 3 of 8 Jessica Andrea Filosa, Georgia Regents University, USA Interpreting the Communication between Cerebral Microvessels and Astrocytes in the Brain
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 4 of 8 Ronald J. Korthuis, University of Missouri, USA Postischemic Arteriolar Dysfunction is Dependent on Venular Leukocyte Adhesion and Mast Cells: Role of Cell-Cell Communication
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 5 of 8 Brant Isakson, University of Virginia, USA Coordinated Function of Endothelial and Vascular Smooth Muscle Cells
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 6 of 8 Gregory Fink, Michigan State University, USA Arteries and Veins: Substrates for Disparate But Integrated Sympathetic Control
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 7 of 8 Cécile Fligny, INSERM, France Short Talk: Are Pericytes Responsible for Renal Interstitial Fibrosis through Transglutaminase-Mediated Collagen Assembly?
Friday, February 27 \| 8:00AM - 11:15AM Influences of Neighboring Cells on Vascular Smooth Muscle Fu nction This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 8 of 8 Lisa A. Lesniewski, University of Colorado, Boulder, USA Short Talk: Age-Associated Endothelial Dysfunction is Associated with IKKbeta-Mediated Reductions in FoxO3a Activity and MnSOD Expression
Friday, February 27 \| 9:20AM - 9:40AM Coffee Break Room: BC Foyer
Friday, February 27 \| 11:15AM - 11:15AM On Own for Lunch
Friday, February 27 \| 11:15AM - 1:00PM Poster Setup Room: Vancouver Island Room
Friday, February 27 \| 1:00PM - 10:00PM Poster Viewing Room: Pacific Ballroom
Friday, February 27 \| 4:30PM - 5:00PM Coffee Available Room: BC Foyer
Friday, February 27 \| 5:00PM - 7:00PM Cellular Mechanisms, Shaping the Nature and Severity of Comp lications Room: Columbia Ballroom Speaker 1 of 4 Erwin P. Böttinger, Hasso-Plattner-Institut für Digital Engineering GmbH, Germany Impact of Podocyte Injury in Diabetes
Friday, February 27 \| 5:00PM - 7:00PM Cellular Mechanisms, Shaping the Nature and Severity of Comp lications Room: Columbia Ballroom Speaker 2 of 4 Thomas M. Coffman, NUS Duke Singapore, Singapore Impact of Hypertension and the Renin-Angiotensin System
Friday, February 27 \| 5:00PM - 7:00PM Cellular Mechanisms, Shaping the Nature and Severity of Comp lications Room: Columbia Ballroom Speaker 3 of 4 * Geoffrey C. Gurtner, Stanford University, USA Impaired Neovascularization in Diabetes and Aging
Friday, February 27 \| 5:00PM - 7:00PM Cellular Mechanisms, Shaping the Nature and Severity of Comp lications Room: Columbia Ballroom Speaker 4 of 4 Sandeep Raha, Hamilton Health Services, Canada Short Talk: Maternal Obesity Results in Placental Mitochondrial Dysfunction and Compromised Neonatal Health
Friday, February 27 \| 5:00PM - 7:00PM Synthesis of the Whole Vessel This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 1 of 6 * Gregory Fink, Michigan State University, USA
Friday, February 27 \| 5:00PM - 7:00PM Synthesis of the Whole Vessel This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 2 of 6 * Nancy J. Rusch, University of Arkansas for Medical Sciences, USA
Friday, February 27 \| 5:00PM - 7:00PM Synthesis of the Whole Vessel This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 3 of 6 David Robertson, Vanderbilt University Medical Center, USA Human Phenotypes and Animal Knockout Models of Genetic Autonomic Disorders
Friday, February 27 \| 5:00PM - 7:00PM Synthesis of the Whole Vessel This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 4 of 6 Paul L. Hermonat, University of Arkansas for Medical Sciences, USA Viral Delivery of Therapeutic Genes for Vascular Pathologies
Friday, February 27 \| 5:00PM - 7:00PM Synthesis of the Whole Vessel This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 5 of 6 David D. Gutterman, Medical College of Wisconsin, USA Human Microvascular Function in Disease: Mechanistic Insights
Friday, February 27 \| 5:00PM - 7:00PM Synthesis of the Whole Vessel This session is from Vasculature Room: British Ballroom Integration of the Vascular Components: The Whole is Greater then the Sum of the Parts Speaker 6 of 6 Hema Raina, University of Maryland, USA Short Talk: Sympathetic Nerve Activity Enhances, and Endothelium Inhibits, the Vasoconstrictor Effect of Low-Dose Ouabain
Friday, February 27 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Pacific Ballroom
Friday, February 27 \| 7:30PM - 10:00PM Poster Session 3 Room: Pacific Ballroom
Saturday, February 28 \| 7:00AM - 8:00AM Breakfast Room: Pacific Ballroom
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 1 of 8 * Ronald J. Korthuis, University of Missouri, USA
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 2 of 8 * Thomas M. Coffman, NUS Duke Singapore, Singapore
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 3 of 8 Susan Quaggin, Northwestern University, USA Angiogenesis and Diabetic Nephropathy
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 4 of 8 Maria B. Grant, University of Florida, USA Vascular Repair Strategies for Diabetic Retinopathy- Mobilization and Differentiation of Hematopoietic Stem Cell by IGFBP-3
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 5 of 8 Geert W. Schmid-Schönbein, University of California, San Diego, USA A Molecular Mechanism for Blood Pressure Elevation, Type II Diabetes, Immune Suppression and Microvascular Rarefaction in the Spontaneously Hypertensive Rat
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 6 of 8 Frank Chip Brosius III, University of Michigan, USA Flipped Signaling: Consequences of Altered Glucose Transporter Expression in Vascular Cells
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 7 of 8 Julia V. Busik, Michigan State University, USA Short Talk: Inhibition of Sphingomyelinases Protects from Inflammation, Vascular Degeneration and Neovascularization in Retinopathy Animal Models
Saturday, February 28 \| 8:00AM - 11:15AM Hypertension and Angiogenesis - Responses to Vascular Injury /Genomics - Disease Models and Human Genomics (Joint) Room: British Columbia Ballroom Speaker 8 of 8 David A. Antonetti, University of Michigan, USA Short Talk: Atypical PKC Inhibitors Block both VEGF and TNF alpha Induced Endothelial Permeability
Saturday, February 28 \| 9:20AM - 9:40AM Coffee Break Room: BC Foyer
Saturday, February 28 \| 11:15AM - 11:15AM On Own for Lunch
Saturday, February 28 \| 4:30PM - 5:00PM Coffee Available Room: BC Foyer
Saturday, February 28 \| 5:00PM - 7:00PM Genetics and Epigenetics Room: Columbia Ballroom Speaker 1 of 4 * John Sedor, Case Western Reserve School of Medicine, USA Genetics of Diabetic Nephropathy
Saturday, February 28 \| 5:00PM - 7:00PM Genetics and Epigenetics Room: Columbia Ballroom Speaker 2 of 4 Rama Natarajan, Beckman Research Institute of City of Hope, USA Epigenetics, Metabolic Memory, Inflammation and Diabetic Complications
Saturday, February 28 \| 5:00PM - 7:00PM Genetics and Epigenetics Room: Columbia Ballroom Speaker 3 of 4 Juro Sakai, University of Tokyo, Japan Short Talk: PPARgamma/RXRalpha Heterodimer Induces Histone Modification Enzyme PR-Set7/Setd8 and Promotes Adipogenesis through a Positive Feedback Loop
Saturday, February 28 \| 5:00PM - 7:00PM Genetics and Epigenetics Room: Columbia Ballroom Speaker 4 of 4 Monika A. Niewczas, Joslin Diabetes Center, USA Short Talk: TNF alpha Related Markers Predict Glomerular Filtration Rate (GFR) Decline but not an Increase in Urinary Albumin Excretion in Patients with Early Diabetic Nephropathy: Results of a Prospective Study
Saturday, February 28 \| 5:00PM - 7:00PM Mechanisms and Targeted Treatment of Vascular Pathologies: F ocus on Hypertension This session is from Vasculature Room: British Ballroom Mechanisms of Vascular Pathologies: Diabetes and Hypertension Speaker 1 of 6 * David D. Gutterman, Medical College of Wisconsin, USA
Saturday, February 28 \| 5:00PM - 7:00PM Mechanisms and Targeted Treatment of Vascular Pathologies: F ocus on Hypertension This session is from Vasculature Room: British Ballroom Mechanisms of Vascular Pathologies: Diabetes and Hypertension Speaker 2 of 6 * R. Clinton Webb, Georgia Regents University, USA
Saturday, February 28 \| 5:00PM - 7:00PM Mechanisms and Targeted Treatment of Vascular Pathologies: F ocus on Hypertension This session is from Vasculature Room: British Ballroom Mechanisms of Vascular Pathologies: Diabetes and Hypertension Speaker 3 of 6 Andrea D. Eckhart, Thomas Jefferson University, USA Novel Mouse Models for Studying Vascular Contributions to Hypertension
Saturday, February 28 \| 5:00PM - 7:00PM Mechanisms and Targeted Treatment of Vascular Pathologies: F ocus on Hypertension This session is from Vasculature Room: British Ballroom Mechanisms of Vascular Pathologies: Diabetes and Hypertension Speaker 4 of 6 Nancy J. Rusch, University of Arkansas for Medical Sciences, USA Ion Channel Expression and Function in Hypertension
Saturday, February 28 \| 5:00PM - 7:00PM Mechanisms and Targeted Treatment of Vascular Pathologies: F ocus on Hypertension This session is from Vasculature Room: British Ballroom Mechanisms of Vascular Pathologies: Diabetes and Hypertension Speaker 5 of 6 Richard A. Cohen, Boston University School of Medicine, USA Redox Regulation of SERCA in Diabetic Vascular Disease
Saturday, February 28 \| 5:00PM - 7:00PM Mechanisms and Targeted Treatment of Vascular Pathologies: F ocus on Hypertension This session is from Vasculature Room: British Ballroom Mechanisms of Vascular Pathologies: Diabetes and Hypertension Speaker 6 of 6 Julian H. Lombard, Medical College of Wisconsin, USA Short Talk: Endothelial Dysfunction and Paradoxical Increase in Vascular Oxidative Stress with Angiotensin II Suppression
Saturday, February 28 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Pacific Ballroom
Saturday, February 28 \| 8:00PM - 11:00PM Entertainment Room: Pacific Ballroom
Saturday, February 28 \| 8:00PM - 11:00PM Cash Bar Room: Pacific Ballroom
Sunday, March 01 \| 10:25AM - 10:25AM Departure *Session Chair.