Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Mechanisms of HIV Persistence: Implications for a Cure (2015E1)
HIV Pathogenesis - Virus vs. Host (2014X4)
Immune Activation in HIV Infection: Basic Mechanisms and Clinical Implications (2013D2)
Frontiers in HIV Pathogenesis, Therapy and Eradication (2012X8)
HIV Evolution, Genomics and Pathogenesis (2011X7)
HIV Biology and Pathogenesis (2010A6)

Web Desc
HIV Immunobiology: From Infection to Immune Control joint with Prevention of HIV/AIDS Organizer(s): Didier Trono, Dana H. Gabuzda and Robert F. Siliciano Date: March 22 - 27, 2009 Location: Keystone Resort, Keystone, CO, USA Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation Summary of Meeting: This meeting will highlight the latest breakthroughs in basic HIV research, ranging from the molecular bases of HIV replication to the host genetic determinants influencing viral spread and disease susceptibility; and from the intricacy of the interaction between HIV and the immune system to the most promising progress in therapeutic development. The meeting will identify new levels of possible intervention to control the progression of HIV-induced disease and, more generally, deepen our understanding of the intimate interaction between retroelements and human hosts. Dynamism will be ensured by having concise, up-to-date talks rather than lengthy lectures, by giving ample room to speakers chosen from the abstracts, and by a close coordination with the concurrent meeting on 'Prevention of HIV/AIDS'. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting, which will share a keynote address and three plenary sessions with this meeting. Global Health Travel Award Deadline: October 14 2008 Scholarship Deadline: November 24 2008 Discounted Abstract Deadline: November 24 2008 Abstract Deadline: December 22 2008 Discounted Registration Deadline: January 22 2009 We gratefully acknowledge additional support for this conference from: GenVec, Inc. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI081594-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

HIV Immunobiology: From Infection to Immune Control

joint with Prevention of HIV/AIDS

Organizer(s): Didier Trono, Dana H. Gabuzda and Robert F. Siliciano

Date: March 22 - 27, 2009
Location: Keystone Resort, Keystone, CO, USA

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation

Summary of Meeting:

This meeting will highlight the latest breakthroughs in basic HIV research, ranging from the molecular bases of HIV replication to the host genetic determinants influencing viral spread and disease susceptibility; and from the intricacy of the interaction between HIV and the immune system to the most promising progress in therapeutic development. The meeting will identify new levels of possible intervention to control the progression of HIV-induced disease and, more generally, deepen our understanding of the intimate interaction between retroelements and human hosts. Dynamism will be ensured by having concise, up-to-date talks rather than lengthy lectures, by giving ample room to speakers chosen from the abstracts, and by a close coordination with the concurrent meeting on 'Prevention of HIV/AIDS'. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting, which will share a keynote address and three plenary sessions with this meeting.

Global Health Travel Award Deadline: October 14 2008

Scholarship Deadline: November 24 2008

Discounted Abstract Deadline: November 24 2008

Abstract Deadline: December 22 2008

Discounted Registration Deadline: January 22 2009

We gratefully acknowledge additional support for this conference from:

GenVec, Inc.

International AIDS Vaccine Initiative (IAVI)

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI081594-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 22 \| 3:00PM - 7:30PM Registration Room: Longs Peak Foyer
Sunday, March 22 \| 6:30PM - 7:30PM Refreshments Room: Longs Peak Foyer
Sunday, March 22 \| 7:30PM - 9:30PM Keynote Address (Joint) Room: Grays Peak / Longs Peak Speaker 1 of 4 * Brigitte Autran, Hôpital Pitié-Salpétrière, UPMC, France
Sunday, March 22 \| 7:30PM - 9:30PM Keynote Address (Joint) Room: Grays Peak / Longs Peak Speaker 2 of 4 * Didier Trono, Ecole Polytechnique Fédérale de Lausanne, Switzerland
Sunday, March 22 \| 7:30PM - 9:30PM Keynote Address (Joint) Room: Grays Peak / Longs Peak Speaker 3 of 4 Françoise Barré-Sinoussi, Institut Pasteur, France HIV Diversity and Pathogenesis
Sunday, March 22 \| 7:30PM - 9:30PM Keynote Address (Joint) Room: Grays Peak / Longs Peak Speaker 4 of 4 Rafi Ahmed, Emory University School of Medicine, USA Vaccination and Immune Memory
Monday, March 23 \| 7:00AM - 8:00AM Breakfast Room: Red Cloud / Shavano / Torreys
Monday, March 23 \| 8:00AM - 11:00AM Host Genomics and HIV Disease (Joint) Room: Columbine Ballroom Speaker 1 of 6 * Didier Trono, Ecole Polytechnique Fédérale de Lausanne, Switzerland
Monday, March 23 \| 8:00AM - 11:00AM Host Genomics and HIV Disease (Joint) Room: Columbine Ballroom Speaker 2 of 6 Amalio Telenti, Centre Hospitalier Universitaire Vaudois, Switzerland Evolutionary and Integrative Genomics of Susceptibility to HIV
Monday, March 23 \| 8:00AM - 11:00AM Host Genomics and HIV Disease (Joint) Room: Columbine Ballroom Speaker 3 of 6 Mary Carrington, NCI, National Institutes of Health, USA Immunogenetic Variation Characterizing Exceptional Control of HIV
Monday, March 23 \| 8:00AM - 11:00AM Host Genomics and HIV Disease (Joint) Room: Columbine Ballroom Speaker 4 of 6 Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA HIV Controllers: A Model for T Cell Vaccination?
Monday, March 23 \| 8:00AM - 11:00AM Host Genomics and HIV Disease (Joint) Room: Columbine Ballroom Speaker 5 of 6 Ioannis Theodorou, INSERM U543, France Short Talk: Distinct Genetic Loci Control Plasma HIV-RNA and Cellular HIV-DNA Levels in HIV-1 Infection: The ANRS Genome Wide Association 01 Study
Monday, March 23 \| 8:00AM - 11:00AM Host Genomics and HIV Disease (Joint) Room: Columbine Ballroom Speaker 6 of 6 David I. Watkins, University of Miami, USA Vaccine-Induced Cellular Responses Control Acute SIV Replication after Heterologous Challenge
Monday, March 23 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Monday, March 23 \| 11:00AM - 11:00AM On Own for Lunch
Monday, March 23 \| 11:00AM - 12:30PM Hands On Computer Workshop on Los Alamos Sequence Database Room: Castle Peaks Maximum attendance: 60. Interested participants may sign up at the meeting on a first-come, first-serve basis.
Monday, March 23 \| 11:00AM - 1:00PM Poster Setup Room: Red Cloud / Shavano / Torreys
Monday, March 23 \| 1:00PM - 10:00PM Poster Viewing Room: Red Cloud / Shavano / Torreys
Monday, March 23 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Monday, March 23 \| 5:00PM - 7:00PM Hiding from Immunity: Reservoirs and Latency Room: Grays/Longs Peaks Speaker 1 of 5 * Douglas D. Richman, University of California, San Diego, USA
Monday, March 23 \| 5:00PM - 7:00PM Hiding from Immunity: Reservoirs and Latency Room: Grays/Longs Peaks Speaker 2 of 5 Robert F. Siliciano, Johns Hopkins University School of Medicine, USA Quantitative Analysis of the Control of HIV Replication by Drugs and Vaccines
Monday, March 23 \| 5:00PM - 7:00PM Hiding from Immunity: Reservoirs and Latency Room: Grays/Longs Peaks Speaker 3 of 5 Joel N. Blankson, Johns Hopkins School of Medicine, USA HIV-1 Latency and Low Level Viremia in Elite Suppressors
Monday, March 23 \| 5:00PM - 7:00PM Hiding from Immunity: Reservoirs and Latency Room: Grays/Longs Peaks Speaker 4 of 5 Dana H. Gabuzda, Dana Farber Cancer Institute, USA Macrophage Reservoirs
Monday, March 23 \| 5:00PM - 7:00PM Hiding from Immunity: Reservoirs and Latency Room: Grays/Longs Peaks Speaker 5 of 5 Matthias Geyer, Max Planck Institute for Molecular Physiology, Germany Short Talk: Structural Insights into the Cyclin T1–Tat–TAR RNA Transcription Activation Complex
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 7 * Glenda E. Gray, South African Medical Research Council, South Africa
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 7 Bertran Auvert, CHU Ambroise Paré, France Circumcision: Uptake and Impact
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 7 Minh H. Dinh, Northwestern University Feinberg School of Medicine, USA Short Talk: HIV-1 Interactions with Adult Human Penile Epithelium
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 7 Barbara L. Shacklett, University of California, Davis, USA Short Talk: Do Mucosal T Cell Responses to HIV-1 Matter?
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 5 of 7 Carolina Herrera, Imperial College, UK Short Talk: Early Colorectal Responses to HIV-1 and Modulation by Microbicides
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 6 of 7 Gilda Tachedjian, Burnet Institute, Australia Short Talk: Enhancement of HIV-1 Infection is Not Intrinsic to Polyanion-Based Microbicides
Monday, March 23 \| 5:00PM - 7:15PM The Bigger Picture: Microbicides, Circumcision and Drugs for Prevention This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 7 of 7 Myron S. Cohen, University of North Carolina at Chapel Hill, USA Antiretroviral Therapy to Prevent Sexual Transmission of HIV-1
Monday, March 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Red Cloud / Shavano / Torreys
Monday, March 23 \| 7:30PM - 10:00PM Poster Session 1 Room: Red Cloud / Shavano / Torreys
Tuesday, March 24 \| 7:00AM - 8:00AM Breakfast Room: Red Cloud / Shavano / Torreys
Tuesday, March 24 \| 8:00AM - 11:00AM Immune Control of HIV and Virus Escape (Joint) Room: Columbine Ballroom Speaker 1 of 6 * Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA
Tuesday, March 24 \| 8:00AM - 11:00AM Immune Control of HIV and Virus Escape (Joint) Room: Columbine Ballroom Speaker 2 of 6 Giuseppe Pantaleo, Centre Hospitalier Universitaire Vaudois, Switzerland Immune Correlates of Protection to HIV
Tuesday, March 24 \| 8:00AM - 11:00AM Immune Control of HIV and Virus Escape (Joint) Room: Columbine Ballroom Speaker 3 of 6 Joseph (Mike) McCune, Bill & Melinda Gates Foundation, USA Short Talk: Immune Control in Pathogenic and Nonpathogenic SIV Infection
Tuesday, March 24 \| 8:00AM - 11:00AM Immune Control of HIV and Virus Escape (Joint) Room: Columbine Ballroom Speaker 4 of 6 Mark Connors, NIAID, National Institutes of Health, USA Short Talk: Effective Control of HIV by CD8+ T-Cells is Associated with Infected CD4+ T Cell Elimination: Ramifications for T Cell Based Vaccines
Tuesday, March 24 \| 8:00AM - 11:00AM Immune Control of HIV and Virus Escape (Joint) Room: Columbine Ballroom Speaker 5 of 6 Philip J. Goulder, University of Oxford, UK HIV Escape and T-Cell Control of HIV
Tuesday, March 24 \| 8:00AM - 11:00AM Immune Control of HIV and Virus Escape (Joint) Room: Columbine Ballroom Speaker 6 of 6 George M. Shaw, University of Pennsylvania, USA HIV-1 Sequences in Acute and Early Infection Reveal the Genetic Identity, Biological Phenotype, and Precise Evolutionary Pathways of Transmitted/Founder Viruses and their Progeny
Tuesday, March 24 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Tuesday, March 24 \| 11:00AM - 11:00AM On Own for Lunch
Tuesday, March 24 \| 11:00AM - 12:30PM Hands On Computer Workshop on Los Alamos Sequence Database Room: Castle Peaks Maximum attendance: 60. Interested participants may sign up at the meeting on a first-come, first-serve basis.
Tuesday, March 24 \| 11:00AM - 1:00PM Poster Setup Room: Red Cloud / Shavano / Torreys
Tuesday, March 24 \| 1:00PM - 10:00PM Poster Viewing Room: Red Cloud / Shavano / Torreys
Tuesday, March 24 \| 2:30PM - 3:30PM Workshop 1A: New Therapeutics Room: Grays/Longs Peaks Speaker 1 of 4 * Dana H. Gabuzda, Dana Farber Cancer Institute, USA
Tuesday, March 24 \| 2:30PM - 3:30PM Workshop 1A: New Therapeutics Room: Grays/Longs Peaks Speaker 2 of 4 Daria J. Hazuda, Merck Research Laboratories, USA Integrase Inhibitors
Tuesday, March 24 \| 2:30PM - 3:30PM Workshop 1A: New Therapeutics Room: Grays/Longs Peaks Speaker 3 of 4 Mike Westby, Pfizer Global Research and Development, UK CCR5 Antagonists as HIV Entry Inhibitors
Tuesday, March 24 \| 2:30PM - 3:30PM Workshop 1A: New Therapeutics Room: Grays/Longs Peaks Speaker 4 of 4 Navid Madani, Dana Farber Cancer Institute, USA New Entry Inhibitors: Interaction of Small-Molecule CD4 Mimics with a Highly Conserved Pocket on the HIV gp120 Envelope Glycoprotein
Tuesday, March 24 \| 3:30PM - 4:30PM Workshop 1B: Th17 Cells Room: Grays/Longs Peaks Speaker 1 of 5 * Robert F. Siliciano, Johns Hopkins University School of Medicine, USA
Tuesday, March 24 \| 3:30PM - 4:30PM Workshop 1B: Th17 Cells Room: Grays/Longs Peaks Speaker 2 of 5 Aimee El Hed, New York University School of Medicine, USA Human Th17 Cells are Highly Susceptible to CCR5-Tropic HIV Infection and are Preferentially Depleted in Infected Individuals
Tuesday, March 24 \| 3:30PM - 4:30PM Workshop 1B: Th17 Cells Room: Grays/Longs Peaks Speaker 3 of 5 Nicolas Manel, Institut Curie, France The Differentiation of Human Th17 Cells Requires TGF-beta and Induction of the Nuclear Receptor RORgammat and this Renders T Cells more Susceptible to HIV-1 Infection
Tuesday, March 24 \| 3:30PM - 4:30PM Workshop 1B: Th17 Cells Room: Grays/Longs Peaks Speaker 4 of 5 Petronela Ancuta, Centre de Recherche de l'Universite de Montreal, Canada HIV Replicates in CCR6+IFN-gamma+IL-17+ but Not CCR6negIFN-gamma+IL-10+ Primary CD4+ T-Cell Subsets
Tuesday, March 24 \| 3:30PM - 4:30PM Workshop 1B: Th17 Cells Room: Grays/Longs Peaks Speaker 5 of 5 Anna Aldovini, Boston Children's Hospital and Harvard Medical School, USA Tat-Induced FOXO3a is a Key Mediator of Apoptosis in HIV-1-Infected Human CD4+ T-Lymphocytes
Tuesday, March 24 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Tuesday, March 24 \| 5:00PM - 7:00PM Models of HIV Immunobiology Room: Grays/Longs Peaks Speaker 1 of 4 * Frank Kirchhoff, University of Ulm, Germany
Tuesday, March 24 \| 5:00PM - 7:00PM Models of HIV Immunobiology Room: Grays/Longs Peaks Speaker 2 of 4 Guido Silvestri, Emory University School of Medicine, USA SIV Infection of African Monkeys: A New Paradigm for AIDS Pathogenesis and Vaccines
Tuesday, March 24 \| 5:00PM - 7:00PM Models of HIV Immunobiology Room: Grays/Longs Peaks Speaker 3 of 4 Cecilia Cheng-Mayer, Aaron Diamond AIDS Research Center (ADARC), USA Coreceptor switching in the SHIV/macaque model
Tuesday, March 24 \| 5:00PM - 7:00PM Models of HIV Immunobiology Room: Grays/Longs Peaks Speaker 4 of 4 Sarah L. Rowland-Jones, Oxford University, UK Long-term non-progression with HIV infection: lessons from HIV-2
Tuesday, March 24 \| 5:00PM - 7:15PM How to Improve Vaccine Efficacy? Adjuvants, Route of Adminis tration... This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 6 * David I. Watkins, University of Miami, USA
Tuesday, March 24 \| 5:00PM - 7:15PM How to Improve Vaccine Efficacy? Adjuvants, Route of Adminis tration... This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 6 Bali Pulendran, Stanford University School of Medicine, USA Modulating Vaccine Responses with Innate Immunity
Tuesday, March 24 \| 5:00PM - 7:15PM How to Improve Vaccine Efficacy? Adjuvants, Route of Adminis tration... This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 6 Susan W. Barnett, Bill & Melinda Gates Foundation, USA HIV Antigen Discovery and Novel Vaccine Deliveries Using Recombinant Alphavirus Replicon Particles and Adjuvanted Proteins
Tuesday, March 24 \| 5:00PM - 7:15PM How to Improve Vaccine Efficacy? Adjuvants, Route of Adminis tration... This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 6 Christopher J. Miller, University of California, Davis, USA A T Cell Vaccine that Elicits Mucosal CD8+ Effector Cells in a Setting of Minimal Immune Activation Can Protect Rhesus Monkeys from Vaginal SIV Challenge
Tuesday, March 24 \| 5:00PM - 7:15PM How to Improve Vaccine Efficacy? Adjuvants, Route of Adminis tration... This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 5 of 6 Barbara K. Felber, NCI, National Institutes of Health, USA Short Talk: Electroporation of Optimized DNA Vaccines Leads to Greatly Enhanced Systemic and Mucosal Immune Responses and Control of Pathogenic SIVmac251 Challenge: Antibodies Contribute to Virus Containment
Tuesday, March 24 \| 5:00PM - 7:15PM How to Improve Vaccine Efficacy? Adjuvants, Route of Adminis tration... This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 6 of 6 Johannes Fabian Scheid, Massachusetts General Hospital - Harvard, USA Short Talk: Search for Broadly Neutralizing Antibodies against HIV using a Single Cell Approach
Tuesday, March 24 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Red Cloud / Shavano / Torreys
Tuesday, March 24 \| 7:30PM - 10:00PM Poster Session 2 Room: Red Cloud / Shavano / Torreys
Wednesday, March 25 \| 7:00AM - 8:00AM Breakfast Room: Red Cloud / Shavano / Torreys
Wednesday, March 25 \| 8:00AM - 11:00AM New Insights in HIV Replication Room: Grays/Longs Peaks Speaker 1 of 6 * Michael H. Malim, King's College London, UK
Wednesday, March 25 \| 8:00AM - 11:00AM New Insights in HIV Replication Room: Grays/Longs Peaks Speaker 2 of 6 Frank Kirchhoff, University of Ulm, Germany Role of Nef in vivo and in vitro
Wednesday, March 25 \| 8:00AM - 11:00AM New Insights in HIV Replication Room: Grays/Longs Peaks Speaker 3 of 6 Christopher Aiken, Vanderbilt University School of Medicine, USA Cyclophilin A and HIV-1 Uncoating
Wednesday, March 25 \| 8:00AM - 11:00AM New Insights in HIV Replication Room: Grays/Longs Peaks Speaker 4 of 6 Nathaniel R. Landau, New York University School of Medicine, USA Vpr and DNA Damage
Wednesday, March 25 \| 8:00AM - 11:00AM New Insights in HIV Replication Room: Grays/Longs Peaks Speaker 5 of 6 John C. Guatelli, University of California, San Diego, USA Short Talk: Vpu Antagonizes BST-2-Mediated Restriction of HIV-1 Release via b-TrCP and Endo-Lysosomal Trafficking
Wednesday, March 25 \| 8:00AM - 11:00AM New Insights in HIV Replication Room: Grays/Longs Peaks Speaker 6 of 6 Andres Finzi, CRCHUM, Université de Montréal, Canada Short Talk: A Layered Structure in the HIV-1 gp120 Inner Domain Regulates gp41 Interaction and Facilitates Transitions into the CD4-Bound Conformation
Wednesday, March 25 \| 8:00AM - 11:00AM How to Generate Vaccine Efficacy against HIV? T Cell-Based and B-Cell Based Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 6 * Giuseppe Pantaleo, Centre Hospitalier Universitaire Vaudois, Switzerland
Wednesday, March 25 \| 8:00AM - 11:00AM How to Generate Vaccine Efficacy against HIV? T Cell-Based and B-Cell Based Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 6 Barton F. Haynes, Duke University Medical Center, USA What Does a Successful HIV-1 Vaccine Need To Do? Clues From Acute HIV-1 Infection
Wednesday, March 25 \| 8:00AM - 11:00AM How to Generate Vaccine Efficacy against HIV? T Cell-Based and B-Cell Based Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 6 Dan H. Barouch, Beth Israel Deaconess Medical Center, USA Novel Adenovirus Vector-Based Vaccines for HIV-1
Wednesday, March 25 \| 8:00AM - 11:00AM How to Generate Vaccine Efficacy against HIV? T Cell-Based and B-Cell Based Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 6 Dennis R. Burton, The Scripps Research Institute, USA Mechanisms of Antibody Protection Against HIV
Wednesday, March 25 \| 8:00AM - 11:00AM How to Generate Vaccine Efficacy against HIV? T Cell-Based and B-Cell Based Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 5 of 6 Peter D. Kwong, NIAID, National Institutes of Health, USA Structure-Based Envelope Immunogens
Wednesday, March 25 \| 8:00AM - 11:00AM How to Generate Vaccine Efficacy against HIV? T Cell-Based and B-Cell Based Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 6 of 6 Amitinder Kaur, New England Regional Primate Research Center, USA Short Talk: Protective Efficacy of a Replication-Defective Herpes Simplex Virus-based AIDS Vaccine Against High Dose Intra-Rectal SIVmac239 Challenge
Wednesday, March 25 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Wednesday, March 25 \| 11:00AM - 11:00AM On Own for Lunch
Wednesday, March 25 \| 11:00AM - 1:00PM Poster Setup Room: Red Cloud / Shavano / Torreys
Wednesday, March 25 \| 1:00PM - 10:00PM Poster Viewing Room: Red Cloud / Shavano / Torreys
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 1 of 8 Carl W. Dieffenbach, NIAID, National Institutes of Health, USA Workshop Objectives
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 2 of 8 * Roger Ptak, Southern Research Institute, USA Cataloging the HIV-Human Protein Interaction Network
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 3 of 8 John A. T. Young, F.Hoffmann-La Roche Ltd, Switzerland Genome-Wide Screeing of HIV-Host Interactions
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 4 of 8 Vineet N. KewalRamani, NCI, National Institutes of Health, USA Regulation of HIV-1 Nuclear Entry
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 5 of 8 * Warner Craig Greene, Gladstone Institute of Virology and Immunology, USA Small Molecule Inhibitors of the Vif-APOBEC3G Interaction of HIV-1 Identified by High Throughput Screening
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 6 of 8 Dana H. Gabuzda, Dana Farber Cancer Institute, USA Small Molecule Inhibitors of the Vif-APOBEC3G Interaction of HIV-1 Identified by High Throughput Screening
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 7 of 8 Tariq M. Rana, University of California, San Diego, USA Small Molecule Inhibitors of the Vif-APOBEC3G Interaction of HIV-1 Identified by High Throughput Screening
Wednesday, March 25 \| 1:30PM - 4:30PM NIAID Workshop on Identification and Validation of New Cellu lar Co-Factors in HIV Replication. Organized by Roger Miller and Opendra Sharma, DAIDS, NIAID. Moderators: Roger Ptak and Warner Greene. Room: Grays/Longs Peaks The objective of the workshop will be to discuss the current status of the field; determine the best approach for validating the mechanism of action of host molecules in primary cells; and, promote development of assays which recreate the activity of a cellular co-factor, or a cellular restriction, with the goal of producing a high throughput screening assay for testing chemical compound libraries. Speaker 8 of 8 Warner Craig Greene, Gladstone Institute of Virology and Immunology, USA Wrap-Up and Future Directions
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 9 * Richard A. Koup, NIAID, National Institutes of Health, USA
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 9 Asier Sáez-Cirión, Institut Pasteur, France The Strong HIV Suppressive Capacity of CD8+ T Cells from HIV Controllers is Associated with Gag-Specific CD8+ T Cell Responses
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 9 Adam R. Hersperger, Thomas Jefferson University, USA HIV-Specific CD8 T Cells from Elite Controllers Rapidly Upregulate Perforin
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 9 Meritxell Genescà, Health Sciences Research Institute Germans Trias i Pujol Foundation, Spain For the CD8+ T Cells to be Effective in the Context of a Live-Attenuated Vaccine Differential Immune Activation is Critical
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 5 of 9 Jorge Ramos de Almeida, NIAID, National Institutes of Health, USA Antigen Sensitivity is a Major Determinant of CD8+ T Cell Efficacy in HIV-1 Infection
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 6 of 9 Leonidas Stamatatos, Fred Hutchinson Cancer Research Center, USA Broad Neutralizing Antibody Responses during HIV-1 Infection: Prevalence and Epitope Specificities
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 7 of 9 Nicole A. Doria-Rose, NIAID, National Institutes of Health, USA Breadth of Neutralizing Antibodies in HIV+ Serum: Clustering Analysis and Association with Clinical Variables
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 8 of 9 Ann J. Hessell, Oregon Health & Science University, USA Complete Protection Provided by Antibodies 2F5 and 4E10 Against Mucosal SHIV BaL Challenge
Wednesday, March 25 \| 2:30PM - 4:30PM Workshop 1: Which Immune Correlates of Protection against HI V? How to Measure T Cell and B Cell Correlates? Supported in part by the French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 9 of 9 Vincent Holl, Institute of Virology, France Identification of HIV-Specific IgG that Inhibit Infection of Mucosal HIV Target Cells
Wednesday, March 25 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Wednesday, March 25 \| 5:00PM - 7:00PM HIV at the Mucosa: Portal of Entry and Front-Line Defense (J oint) Room: Columbine Ballroom Speaker 1 of 5 * Daniel C. Douek, NIAID, National Institutes of Health, USA
Wednesday, March 25 \| 5:00PM - 7:00PM HIV at the Mucosa: Portal of Entry and Front-Line Defense (J oint) Room: Columbine Ballroom Speaker 2 of 5 Ashley T. Haase, University of Minnesota, USA Keynote Address: Quest for Design Principles for an Effective HIV Vaccine/Microbicide in Studies of SIV Pathogenesis
Wednesday, March 25 \| 5:00PM - 7:00PM HIV at the Mucosa: Portal of Entry and Front-Line Defense (J oint) Room: Columbine Ballroom Speaker 3 of 5 Alison Simmons, Weatherall Institute of Molecular Medicine, UK Dendritic Cell Factors Required for HIV-1 Infection
Wednesday, March 25 \| 5:00PM - 7:00PM HIV at the Mucosa: Portal of Entry and Front-Line Defense (J oint) Room: Columbine Ballroom Speaker 4 of 5 Ronald S. Veazey, Tulane National Primate Research Center, USA _7 Integrin Expression on CD4+ T Cells as a Surrogate Marker for Tracking Intestinal CD4+ T Cell Loss in SIV Infection
Wednesday, March 25 \| 5:00PM - 7:00PM HIV at the Mucosa: Portal of Entry and Front-Line Defense (J oint) Room: Columbine Ballroom Speaker 5 of 5 Satya Dandekar, University of California, Davis, USA Short Talk: Mechanisms of Impaired Gut Mucosal Defenses during HIV and SIV Infections
Wednesday, March 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Red Cloud / Shavano / Torreys
Wednesday, March 25 \| 7:30PM - 10:00PM Poster Session 3 Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 7:00AM - 8:00AM Breakfast Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 7:00AM - 8:00AM Poster Setup Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 8:00AM - 11:00AM Innate Antiviral Immunity Room: Grays/Longs Peaks Speaker 1 of 5 * Christopher Aiken, Vanderbilt University School of Medicine, USA
Thursday, March 26 \| 8:00AM - 11:00AM Innate Antiviral Immunity Room: Grays/Longs Peaks Speaker 2 of 5 Michael H. Malim, King's College London, UK APOBEC3 Proteins and Intrinsic Resistance to HIV-1 Infection
Thursday, March 26 \| 8:00AM - 11:00AM Innate Antiviral Immunity Room: Grays/Longs Peaks Speaker 3 of 5 Warner Craig Greene, Gladstone Institute of Virology and Immunology, USA The Role of APOBEC3 Enzymes in Counteracting “Retro-Threats”, Both Foreign and Domestic
Thursday, March 26 \| 8:00AM - 11:00AM Innate Antiviral Immunity Room: Grays/Longs Peaks Speaker 4 of 5 Greg J. Towers, University College London, UK Inhibition of Retroviral Infection by TRIMCyp and Tetherin Reveals a Delicate Balance between Viral Countermeasures and Host Restriction
Thursday, March 26 \| 8:00AM - 11:00AM Innate Antiviral Immunity Room: Grays/Longs Peaks Speaker 5 of 5 Didier Trono, Ecole Polytechnique Fédérale de Lausanne, Switzerland Epigenetic Control of Retroelements
Thursday, March 26 \| 8:00AM - 11:15AM HIV-HSV-2 Interactions and Lessons from Clinical Trials of P reventative Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 5 Lawrence Corey, Fred Hutchinson Cancer Research Center, USA Mechanism behind the HSV-2-HIV Interaction: Subclinical Persistence of HIV Receptor Positive Cells
Thursday, March 26 \| 8:00AM - 11:15AM HIV-HSV-2 Interactions and Lessons from Clinical Trials of P reventative Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 5 * Scott M. Hammer, Columbia University, USA Challenges in Preventative Vaccine Development
Thursday, March 26 \| 8:00AM - 11:15AM HIV-HSV-2 Interactions and Lessons from Clinical Trials of P reventative Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 5 Susan P. Buchbinder, San Francisco Department of Public Health, USA Clinical Endpoints in the Step Study
Thursday, March 26 \| 8:00AM - 11:15AM HIV-HSV-2 Interactions and Lessons from Clinical Trials of P reventative Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 5 M. Juliana McElrath, Fred Hutchinson Cancer Research Center, USA Lessons from the HIV-Ad5 Vaccine Phase II Clinical Trial
Thursday, March 26 \| 8:00AM - 11:15AM HIV-HSV-2 Interactions and Lessons from Clinical Trials of P reventative Vaccines This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 5 of 5 Merlin L. Robb, Walter Reed Army Institute of Research, USA Lessons from the Thai ALVAC-gp120 HIV Vaccine Efficacy Trial: A Community Based Study
Thursday, March 26 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Thursday, March 26 \| 11:00AM - 12:00PM Lunch Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 12:00PM - 2:30PM Poster Session 4 Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 2:30PM - 4:30PM Workshop 2: Clinical Trials Design. Supported in part by th e French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 5 * Scott M. Hammer, Columbia University, USA
Thursday, March 26 \| 2:30PM - 4:30PM Workshop 2: Clinical Trials Design. Supported in part by th e French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 5 Dean Follmann, NIH: National Institute of Allergy and Infectious Diseases (NIAID), USA Crossover Designs for HIV Prevention Trials
Thursday, March 26 \| 2:30PM - 4:30PM Workshop 2: Clinical Trials Design. Supported in part by th e French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 5 Peter Gilbert, Fred Hutchinson Cancer Research Center, USA Leveraging Baseline Characteristics to Improve Prevention Trials
Thursday, March 26 \| 2:30PM - 4:30PM Workshop 2: Clinical Trials Design. Supported in part by th e French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 5 Frances Priddy, International AIDS Vaccine Initiative, USA HIV Vaccines and PrEP
Thursday, March 26 \| 2:30PM - 4:30PM Workshop 2: Clinical Trials Design. Supported in part by th e French Agency for AIDS Research (ANRS) This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 5 of 5 Heather B. Jaspan, University of Cape Town, South Africa HIV Vaccine Trials in Adolescents
Thursday, March 26 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Thursday, March 26 \| 5:00PM - 7:15PM Virus Spread Room: Grays/Longs Peaks Speaker 1 of 6 * Alison Simmons, Weatherall Institute of Molecular Medicine, UK
Thursday, March 26 \| 5:00PM - 7:15PM Virus Spread Room: Grays/Longs Peaks Speaker 2 of 6 Olivier Schwartz, Institut Pasteur, France Mechanisms of Direct HIV Lymphocyte-to-Lymphocyte Transfer: Role of “Polysynapses”
Thursday, March 26 \| 5:00PM - 7:15PM Virus Spread Room: Grays/Longs Peaks Speaker 3 of 6 Thomas J. Hope, Northwestern University, USA Interaction of HIV with Cells within Intact Mucosal Tissue
Thursday, March 26 \| 5:00PM - 7:15PM Virus Spread Room: Grays/Longs Peaks Speaker 4 of 6 Vincent Piguet, Cardiff University, UK Mechanisms of DC-T Cell HIV-1 Transmission via an Infectious Synapse
Thursday, March 26 \| 5:00PM - 7:15PM Virus Spread Room: Grays/Longs Peaks Speaker 5 of 6 Walther Mothes, Yale University School of Medicine, USA Short Talk: Retroviral Assembly is Directed Towards Sites of Cell-Cell Contact
Thursday, March 26 \| 5:00PM - 7:15PM Virus Spread Room: Grays/Longs Peaks Speaker 6 of 6 Sriram Subramaniam, University of British Columbia, Canada Short Talk: 3D Architecture of the Virological Synapse and Structural Mechanisms of HIV Entry
Thursday, March 26 \| 5:00PM - 7:00PM Prevention of AIDS: What can we Learn from Therapeutic Vacci nes This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 1 of 4 Brigitte Autran, Hôpital Pitié-Salpétrière, UPMC, France Lessons for Therapeutic Vaccines against HIV for Immune Correlates of Protection against HIV
Thursday, March 26 \| 5:00PM - 7:00PM Prevention of AIDS: What can we Learn from Therapeutic Vacci nes This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 2 of 4 * Rafick Sekaly, Emory University, USA Improving and Modeling of Therapeutic Autologous Dendritic Cell Vaccine for HIV-1 Infection
Thursday, March 26 \| 5:00PM - 7:00PM Prevention of AIDS: What can we Learn from Therapeutic Vacci nes This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 3 of 4 Stephen J. Kent, University of Melbourne, Australia Short Talk: Reduced Viremia and Delayed Disease Progression Following Immunotherapy of SIV with Antigen Pulsed Blood
Thursday, March 26 \| 5:00PM - 7:00PM Prevention of AIDS: What can we Learn from Therapeutic Vacci nes This session is from Prevention of HIV/AIDS (Vac) Room: Quandary Speaker 4 of 4 Glenda E. Gray, South African Medical Research Council, South Africa HIV Vaccine Trials in South Africa: Looking Forward from Phambili
Thursday, March 26 \| 7:15PM - 8:00PM Social Hour with Lite Bites Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 8:00PM - 11:00PM Entertainment Room: Red Cloud / Shavano / Torreys
Thursday, March 26 \| 8:00PM - 11:00PM Cash Bar Room: Red Cloud / Shavano / Torreys
Friday, March 27 \| 10:25AM - 10:25AM Departure *Session Chair.