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Web Desc
Pattern Recognition Molecules and Immune Sensors of Pathogens joint with Dendritic Cells Organizer(s): Jenny P. Ting, Richard A. Flavell and Luke A.J. O'Neill Date: March 29 - April 03, 2009 Location: Fairmont Banff Springs, Banff, AB, Canada Supported by the Directors' Fund Summary of Meeting: The discovery of evolutionarily conserved immune genes and pathways has led to an explosive discovery phase in innate immunity. These pathways include TLR, NLR, C-type lectin Receptor, and the helicase-containing anti-viral proteins. These novel pathways merge the innate and adaptive branches of immunity, and converge on a wide range of disorders including infectious diseases, inflammation and autoimmunity. All of the above have systemic effects that can affect the outcome of a wide range of diseases ranging from cancer to cardiovascular disorders. Scholarship Deadline: December 2 2008 Discounted Abstract Deadline: December 2 2008 Abstract Deadline: December 31 2008 Discounted Registration Deadline: January 29 2009 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Genentech, Inc. Pfizer Research Technology Center We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI082784-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Pattern Recognition Molecules and Immune Sensors of Pathogens

joint with Dendritic Cells

Organizer(s): Jenny P. Ting, Richard A. Flavell and Luke A.J. O'Neill

Date: March 29 - April 03, 2009
Location: Fairmont Banff Springs, Banff, AB, Canada

Supported by the Directors' Fund

Summary of Meeting:

The discovery of evolutionarily conserved immune genes and pathways has led to an explosive discovery phase in innate immunity. These pathways include TLR, NLR, C-type lectin Receptor, and the helicase-containing anti-viral proteins. These novel pathways merge the innate and adaptive branches of immunity, and converge on a wide range of disorders including infectious diseases, inflammation and autoimmunity. All of the above have systemic effects that can affect the outcome of a wide range of diseases ranging from cancer to cardiovascular disorders.

Scholarship Deadline: December 2 2008

Discounted Abstract Deadline: December 2 2008

Abstract Deadline: December 31 2008

Discounted Registration Deadline: January 29 2009

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

Pfizer Research Technology Center

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI082784-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 29 \| 3:00PM - 7:30PM Registration Room: Van Horne Foyer
Sunday, March 29 \| 6:30PM - 7:30PM Refreshments Room: Van Horne Foyer
Sunday, March 29 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Van Horne Ballroom Speaker 1 of 4 * Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA
Sunday, March 29 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Van Horne Ballroom Speaker 2 of 4 * Giorgio Trinchieri, NCI, National Institutes of Health, USA
Sunday, March 29 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Van Horne Ballroom Speaker 3 of 4 Akira Shizuo, Osaka University, Japan TLRs and Inflammation
Sunday, March 29 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Van Horne Ballroom Speaker 4 of 4 Ira Mellman, Genentech, Inc., USA Cell Biology of Antigen Processing by Dendritic Cells
Monday, March 30 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Monday, March 30 \| 7:00AM - 8:00AM Poster Setup Room: Mezzanine 2
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 1 of 8 * Siamon Gordon, Chang Gung University / University of Oxford, UK
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 2 of 8 Bruce A. Beutler, University of Texas Southwestern Medical Center, USA Mutagenesis in the Analysis of Pathogen Sensing Pathways
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 3 of 8 Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland The IL-1 Receptor / Toll-Like Receptor Superfamily: 10 Years of Progress
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 4 of 8 Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA A Mechanism of an Allergen-Induced Immune Response
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 5 of 8 Eicke Latz, University of Bonn, Germany Pattern Recognition + Nalp3 Inflammasome
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 6 of 8 Sarah Ewald, Stanford University, USA Short Talk: The Ectodomain of Toll-like Receptor 9 is Cleaved to Generate a Functional Receptor
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 7 of 8 Markus G. Manz, University Hospital Zürich, Switzerland Short Talk: Human Bone Marrow Multipotent Mesenchymal Stromal Cells Sense TLR4-Agonists and Subsequently Enhance Myelopoiesis
Monday, March 30 \| 8:00AM - 11:15AM TLRs - I Room: Van Horne Ballroom A,B Speaker 8 of 8 Stephanie C. Eisenbarth, Yale University, USA Short Talk: Activation of Adaptive Immunity but not Th2 Differentiation by the Nalp3 Inflammasome
Monday, March 30 \| 8:00AM - 11:30AM Phagocytosis and Antigen Presentation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 6 * Ira Mellman, Genentech, Inc., USA
Monday, March 30 \| 8:00AM - 11:30AM Phagocytosis and Antigen Presentation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 6 Sebastian Amigorena, Institut Curie, France A New Soluble Ligand of DCSign Present in Human Semen Inhibits HIV Trans-Infection of T Cells
Monday, March 30 \| 8:00AM - 11:30AM Phagocytosis and Antigen Presentation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 6 David G. Russell, Cornell University, USA Reprogramming Phagosomal Function in Macrophages and Dendritic Cells
Monday, March 30 \| 8:00AM - 11:30AM Phagocytosis and Antigen Presentation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 6 Jose A. Villadangos, University of Melbourne, Australia Antigen Presentation Specializations in the Dendritic Cell Network
Monday, March 30 \| 8:00AM - 11:30AM Phagocytosis and Antigen Presentation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 5 of 6 Romina S. Goldszmid, NCI, National Institutes of Health, USA Short Talk: Host ER-Parasitophorous Vacuole Interaction Provides a Route of Entry for Antigen Cross-Presentation in Toxoplasma Infected Dendritic Cells
Monday, March 30 \| 8:00AM - 11:30AM Phagocytosis and Antigen Presentation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 6 of 6 Bali Pulendran, Stanford University School of Medicine, USA Modulating Vaccine Responses with Innate Immunity
Monday, March 30 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Monday, March 30 \| 11:15AM - 12:30PM Lunch Room: Mezzanine 2
Monday, March 30 \| 12:00PM - 2:30PM Poster Session 1 Room: Mezzanine 2
Monday, March 30 \| 12:00PM - 5:00PM Poster Viewing Room: Mezzanine 2
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 1 of 8 Michael Carty, Trinity College Dublin, Ireland Regulation of TRIF- dependent TLR Signaling by the Adaptor SARM
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 2 of 8 Ping Zhang, University of Alabama, Birmingham, USA TLR2-dependent Modulation of Osteoclastogenesis by Porphyromonas gingivalis
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 3 of 8 Brendan J. Jenkins, Hudson Institute of Medical Research, Australia Interplay between the Interleukin-6 Cytokine Family and Toll-like Receptors in Inflammation and Gastric Tumorigenesis
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 4 of 8 Jaime Pascual, Sanford-Burnham Medical Research Institute, USA Molecular Mimicry in Innate Immunity: Crystal Structure of a Bacteria TIR Virulence Factor
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 5 of 8 Kathryn J. Moore, New York University Medical Center, USA CD36 Ligands Promote Sterile Inflammation through Assembly of a TLR 4 and 6 Heterodimer
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 6 of 8 Emily L. Lowe, University of California, Los Angeles, USA TLR2 is Protective in Colitis-associated Colorectal Cancer
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 7 of 8 Yue Guan, University of Illinois at Urbana-Champaign, USA Human Toll-like Receptors 10 and 1 Share Common Mechanisms of Innate Immune Sensing but not Signaling
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: TLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 8 of 8 Anca Dorhoi, Friedrich-Loeffler-Institut, Germany The Adaptor Protein CARD9 is Essential for Tuberculosis Control
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 1 of 9 * Sebastian Amigorena, Institut Curie, France
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 2 of 9 Sofia Bogiatzi, Institut Curie, France Reciprocal Inhibition of the TSLP and Th17 Immune Pathways
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 3 of 9 Anuradha Ray, University of Pittsburgh School of Medicine, USA Dual c-kit-Stem Cell Factor Upregulation by Allergens in Dendritic Cells Promotes IL-6 but Limits IL-12 Impacting T Helper Cell Differentiation and Allergic Asthma
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 4 of 9 Thomas Duhen, Agonox, USA Identification and Characterization of IL-22-Only Producing CD4+ T Cells: Role of Plasmacytoid DC for their Differentiation
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 5 of 9 Guillaume Hoeffel, Singapore Immunology Network, Singapore HIV Antigen Crosspresentation Pathways from Apoptotic, Infected CD4+ T Cells, in Plasmacytoid Dendritic Cell
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 6 of 9 Roger V. Belizaire, Washington University in St. Louis, USA Exogenous Antigen Enters the Major Histocompatibility Complex (MHC) Class I Processing and Presentation Pathway via Multiple Endocytic Compartments with Distinct Molecular and Proteolytic Requirements
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 7 of 9 Roberto A. Maldonado, Selecta Biosciences, USA Rapamycin- and TGFbeta-Treated Dendritic Cells Induce Tolerance and de novo Differentiation of Regulatory T Cells in vitro and in vivo
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 8 of 9 Mireille H. Lahoud, Burnet Institute, Australia Clec9A on the Surface of Dendritic Cells is a Dead Cell Recognition Molecule
Monday, March 30 \| 2:30PM - 4:30PM Workshop 1: Antigen Presentation and T Cell Activation This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 9 of 9 David Sancho, CNIC-Fundación Centro Nacional de Investigaciones Cardiovasculares, Spain Identification of a Dendritic Cell Receptor that Couples Sensing of Necrosis to Immunity
Monday, March 30 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Monday, March 30 \| 5:00PM - 7:00PM TLRs - II Room: Van Horne Ballroom A,B Speaker 1 of 5 * Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Monday, March 30 \| 5:00PM - 7:00PM TLRs - II Room: Van Horne Ballroom A,B Speaker 2 of 5 Siamon Gordon, Chang Gung University / University of Oxford, UK Regulation of Macrophage Function by Surface Receptors and TH2 Cytokines
Monday, March 30 \| 5:00PM - 7:00PM TLRs - II Room: Van Horne Ballroom A,B Speaker 3 of 5 Ann Marshak-Rothstein, University of Massachusetts Medical School, USA BCR, TLR and IFNaR Regulation of Autoreactive B Cells
Monday, March 30 \| 5:00PM - 7:00PM TLRs - II Room: Van Horne Ballroom A,B Speaker 4 of 5 Arthur M. Krieg, Checkmate Pharmaceuticals, USA Therapeutic Usage of Nucleic Acid TLR Agonists
Monday, March 30 \| 5:00PM - 7:00PM TLRs - II Room: Van Horne Ballroom A,B Speaker 5 of 5 Wajahat Z. Mehal, Yale University, USA Short Talk: Acetaminophen Induced Hepatotoxicity is Dependent on TLR7/9 and the NALP3 Inflammasome
Monday, March 30 \| 5:00PM - 7:00PM DCs in Tolerance, Immunity, and T Cell Differentiation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 5 * Bali Pulendran, Stanford University School of Medicine, USA
Monday, March 30 \| 5:00PM - 7:00PM DCs in Tolerance, Immunity, and T Cell Differentiation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 5 Daniel J. Cua, Janssen Pharmaceutical Companies of Johnson & Johnson, USA The IL-23/IL-17 Axis
Monday, March 30 \| 5:00PM - 7:00PM DCs in Tolerance, Immunity, and T Cell Differentiation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 5 Yong-Jun Liu, Sanofi, USA Thymic Stromal Lymphopoietin Program Dendritic Cells to Induce TH2 Inflammation through a Unique Set of Signal Codes
Monday, March 30 \| 5:00PM - 7:00PM DCs in Tolerance, Immunity, and T Cell Differentiation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 5 Erica L. Granger, Pennsylvania State College of Medicine, USA Short Talk: Persistence of MHC Class I-Restricted Antigen Presentation Following Acute Virus Infection Requires Direct and then Cross Presentation
Monday, March 30 \| 5:00PM - 7:00PM DCs in Tolerance, Immunity, and T Cell Differentiation This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 5 of 5 Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA Tim-3 and Expansion of Regulatory Antigen Presenting Cells
Monday, March 30 \| 7:00PM - 7:00PM On Own for Dinner
Tuesday, March 31 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 1 of 7 * Jürg Tschopp, University of Lausanne, Switzerland
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 2 of 7 Jonathan D.G. Jones, Sainsbury Laboratory, UK Using Pathogen Effectors to Understand Host Resistance Mechanisms
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 3 of 7 Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA NLR in Diseases and Health
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 4 of 7 Vishva M. Dixit, Genentech, Inc., USA The Inflammasone: A Dynamic Caspase Activating Apparatus
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 5 of 7 John C. Reed, Sanofi, France Linking Innate Immunity with the Cell Death Machinery: Interactions of NLR and Bcl-2 Family Proteins
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 6 of 7 Tara L. Roberts, Queensland Institute of Medical Research, Australia Short Talk: The Role of HIN200 Family Proteins in the Response to Cytosolic DNA
Tuesday, March 31 \| 8:00AM - 11:15AM NLR/NBD-LRR Proteins, Pathways and Diseases Room: Van Horne Ballroom A,B Speaker 7 of 7 Tsan Sam Xiao, Case Western Reserve University, USA Short Talk: The Structure of NALP1/NLRP1 Leucine-rich Repeats Illustrates a Potential Ligand-binding Site
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 7 * Gwendalyn J. Randolph, Washington University, USA
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 7 Carlos Ardavin, National Center for Biotechnology, Spain Monocyte-Derived Dendritic Cells
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 7 Steffen Jung, Weizmann Institute of Science, Israel Probing Origins and in vivo Functions of Dendritic Cells
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 7 Markus G. Manz, University Hospital Zürich, Switzerland Lymphoid-Organ Dendritic Cell Homeostasis in Steady-State and Inflammation
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 5 of 7 Kang Liu, Columbia University Medical Center, USA Short Talk: Dendritic Cell Development and Homeostasis in vivo
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 6 of 7 Boris Reizis, New York University Langone Medical Center, USA Plasmacytoid Dendritic Cell Differentiation
Tuesday, March 31 \| 8:00AM - 11:15AM Dendritic Cell Precursors This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 7 of 7 Florent Ginhoux, Singapore Immunology Network, Singapore Short Talk: Flt3 and Id2-Dependent CD103+ DCs in Non-Lymphoid Tissues Form a Specific DC Lineage Related to Lymphoid CD8+ DCs
Tuesday, March 31 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Tuesday, March 31 \| 11:00AM - 1:00PM Poster Setup Room: Mezzanine 2
Tuesday, March 31 \| 11:15AM - 11:15AM On Own for Lunch
Tuesday, March 31 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Tuesday, March 31 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Tuesday, March 31 \| 5:00PM - 7:00PM NLR/NBD-LRR Proteins, Pathways and Diseases - II Room: Van Horne Ballroom A,B Speaker 1 of 5 * Vishva M. Dixit, Genentech, Inc., USA
Tuesday, March 31 \| 5:00PM - 7:00PM NLR/NBD-LRR Proteins, Pathways and Diseases - II Room: Van Horne Ballroom A,B Speaker 2 of 5 Jürg Tschopp, University of Lausanne, Switzerland Malarial Hemozoin is a Nalp3 Inflammasome Activating Danger Signal
Tuesday, March 31 \| 5:00PM - 7:00PM NLR/NBD-LRR Proteins, Pathways and Diseases - II Room: Van Horne Ballroom A,B Speaker 3 of 5 Gabriel Nuñez, University of Michigan, USA Function of Nod-Like Receptors in Innate Immunity
Tuesday, March 31 \| 5:00PM - 7:00PM NLR/NBD-LRR Proteins, Pathways and Diseases - II Room: Van Horne Ballroom A,B Speaker 4 of 5 Dana Philpott, University of Toronto, Canada Nod Proteins and the Interaction of Innate and Adaptive Immunity
Tuesday, March 31 \| 5:00PM - 7:00PM NLR/NBD-LRR Proteins, Pathways and Diseases - II Room: Van Horne Ballroom A,B Speaker 5 of 5 Koichi S. Kobayashi, Texas A&M Health Science Center, USA Short Talk: The Role of Nod2-Rip2 Signaling Pathway in the Regulation of Commensal Microbiota in the Intestine
Tuesday, March 31 \| 5:00PM - 7:00PM Recent Advances This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 4 * Maria Rescigno, Humanitas University, Italy
Tuesday, March 31 \| 5:00PM - 7:00PM Recent Advances This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 4 Dominique Kaiserlian, INSERM U851, France Role of Liver Plasmacytoid DC in Oral Tolerance
Tuesday, March 31 \| 5:00PM - 7:00PM Recent Advances This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 4 Yvette van Kooyk, Vrije University Medical Center, Netherlands Targeting of DC by Glycosylated Antigens
Tuesday, March 31 \| 5:00PM - 7:00PM Recent Advances This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 4 Ana-Maria Lennon-Duménil, Curie Institute, France Coordinated Regulation of Antigen Presentation and Dendritic Cell Migration
Tuesday, March 31 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Mezzanine 2
Tuesday, March 31 \| 7:30PM - 10:00PM Poster Session 2 Room: Mezzanine 2
Wednesday, April 01 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 1 of 7 * Akira Shizuo, Osaka University, Japan
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 2 of 7 Takashi Fujita, Institute for Frontier Life and Medical Sciences, Kyoto University, Japan Solution Structures of MDA5 and LGP2 C-Terminal Domains: Identification of the RNA Recognition Loop in RIG-I Like Receptors
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 3 of 7 Hong-Bing Shu, Wuhan University, China Virus-Triggered Signaling Pathways
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 4 of 7 Caetano Reis e Sousa, Francis Crick Institute, UK Innate Anti-Viral Responses
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 5 of 7 Kate A. Fitzgerald, University of Massachusetts Medical School, USA Molecular Mechanisms of DNA Sensing
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 6 of 7 Stephanie J. DeWitte-Orr, McMaster University, Canada Short Talk: Scavenger Class A-Like Receptor (SLR): A Pathogen Recognition Receptor Mediating DsRNA-Induced Antiviral Responses
Wednesday, April 01 \| 8:00AM - 11:15AM Viral Sensors Room: Van Horne Ballroom A,B Speaker 7 of 7 Axel Kirchhofer, Gene Center, Germany Short Talk: Structural and Functional Analysis of RIG-I Like Helicases
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 7 * Yong-Jun Liu, Sanofi, USA
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 7 Miriam Merad, Mount Sinai School of Medicine, USA Origin of Dendritic Cell Diversity Controls Tissue Immunity
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 7 Gwendalyn J. Randolph, Washington University, USA Monocytes, Dendritic Cells, and their Migration in Atherosclerosis
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 7 Jerry Aldridge, St. Jude Children's Research Hospital, USA Short Talk: tipDCs — The Necessary Evil of Lethal Influenza Infection
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 5 of 7 Maria Rescigno, Humanitas University, Italy DCs in Intestinal Disease
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 6 of 7 Giorgio Trinchieri, NCI, National Institutes of Health, USA TLR Signaling in DC: Lessons from Fibroblasts
Wednesday, April 01 \| 8:00AM - 11:15AM Dendritic Cells in Disease This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 7 of 7 Vanja Sisirak, Columbia University, USA Short Talk: Breast Tumor Environment Alters Human Plasmacytoid Dendritic Cells Functions
Wednesday, April 01 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Wednesday, April 01 \| 11:00AM - 1:00PM Poster Setup Room: Mezzanine 2
Wednesday, April 01 \| 11:15AM - 11:15AM On Own for Lunch
Wednesday, April 01 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 1 of 9 * Gordon D. Brown, University of Aberdeen, UK
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 2 of 9 Olaf Groß, Universitätsklinikum Freiburg, Germany Adjuvanticity of the Synthetic Cord Factor Analog TDB for subunit M. tuberculosis Vaccination Requires Card9-dependent Innate Immune Activation
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 3 of 9 Tilmann Bürckstümmer, Haplogen Genomics, Austria An Orthogonal Proteomic/Genomic Screen Identifies DSIRE as Cytoplasmic DNA Sensor for the Inflammasome
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 4 of 9 Paul G. Thomas, St. Jude Children's Research Hospital, USA NLRP3 (NALP3/CIAS1/Cryopyrin) Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 5 of 9 Joseph A. Duncan, University of North Carolina, Chapel Hill, USA Staphylococcus aureus a-hemolysin Induces IL-1B Production and Inflammatory Cell Death through Activation of Host NLRP3
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 6 of 9 Monique Willart, Ghent University, Belgium
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 7 of 9 Edward A. Miao, University of North Carolina at Chapel Hill, USA NLRC4 is an Innate Immune Detector of the Bacterial Type III Secretion Apparatus
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 8 of 9 Takeshi Ichinohe, Yale University School of Medicine, USA Inflammasome Recognition of Influenza Virus is Essential for Adaptive Immune Responses
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: NLR and Other Pathogen Sensors Room: Van Horne Ballroom A,B Speaker 9 of 9 Fengyi Wan, Johns Hopkins Bloomberg School of Public Health, USA Ribosomal Protein S3: A Novel Non-Rel Subunit of NF-kappaB Confers Regulatory Specificity
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: Systems Biology of Dendritic Cells Suppor ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative This session is from Dendritic Cells Room: Shaughnessy/Beatty The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells. Speaker 1 of 6 Sonja I. Buschow, Nijmegen Centre for Molecular Life Sciences (NCMLS) St. Radboud UMC, Netherlands DC-ATLAS: Dissecting Signal Transduction in the Dendritic Cell with a Systems Biology Approach
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: Systems Biology of Dendritic Cells Suppor ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative This session is from Dendritic Cells Room: Shaughnessy/Beatty The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells. Speaker 2 of 6 Laszlo Nagy, Sanford-Burnham Medical Research Institute at Lake Nona, USA Interrelated Nuclear Receptor Signaling Connects Lipids, the Genome and Immune Function in Dendritic Cells
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: Systems Biology of Dendritic Cells Suppor ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative This session is from Dendritic Cells Room: Shaughnessy/Beatty The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells. Speaker 3 of 6 * Uri Hershberg, Drexel University, USA Transcriptional Cascades in Dendritic Cells during Anti-Viral Responses
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: Systems Biology of Dendritic Cells Suppor ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative This session is from Dendritic Cells Room: Shaughnessy/Beatty The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells. Speaker 4 of 6 Simeone Marino, University of Michigan Medical School, USA Roles of Dendritic Cells in the Immune Response to Bacterial and Viral Infections
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: Systems Biology of Dendritic Cells Suppor ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative This session is from Dendritic Cells Room: Shaughnessy/Beatty The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells. Speaker 5 of 6 Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland A Systems Immunological Approach to Plasmacytoid Dendritic Cell Function in Cytophatic Virus Infection
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 2: Systems Biology of Dendritic Cells Suppor ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative This session is from Dendritic Cells Room: Shaughnessy/Beatty The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells. Speaker 6 of 6 Elodie Segura, Walter and Elizabeth Hall Institute, Australia Novel Functional Specialization of Dendritic Cell Subsets Revealed by Plasma Membrane Comparative Proteomic Analysis
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 1 of 8 * Tsan Sam Xiao, Case Western Reserve University, USA
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 2 of 8 William J. Kaiser, Emory University School of Medicine, USA RHIM-dependent Control of NF-kappaB and Cell Death Activation via the DNA-dependent Activator of Interferon Regulatory Factors (DAI/ZBP1/DLM-1)
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 3 of 8 Pingwei Li, Texas A&M University, USA The RIG-I Like Receptor LGP2 Recognizes the Termini of Double-Stranded RNA
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 4 of 8 Julien Pothlichet, Institut Pasteur, France A Comprehensive Study of Human RIG-I Single-Nucleotide Polymorphisms (SNPs) Identifies Two Variants with a Major Functional Impact on Antiviral Host Response
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 5 of 8 Mehul S. Suthar, University of Washington, USA The RLR Signaling Pathway is Essential in Triggering an Innate Immune Response to WNV Infection
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 6 of 8 Szu-Ting Chen, National Yang Ming University, Taiwan CLEC5A, A Pattern Recognition Receptor to Flavivirus
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 7 of 8 Terry K. Means, Massachusetts General Hospital, USA RNAi Identifies an Important Role for Scavenger Receptors in Fungal Immunity
Wednesday, April 01 \| 2:30PM - 4:30PM Workshop 3: RLH and Other Pathogen Sensors Room: Van Horne Ballroom C Speaker 8 of 8 Juergen M. Ruland, Technical University of Munich, Germany
Wednesday, April 01 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Wednesday, April 01 \| 5:00PM - 7:00PM Evolution of Pattern Recognition Molecules Room: Van Horne Ballroom A,B Speaker 1 of 4 * Max D. Cooper, Emory University, USA Evolution of LRR- Based Variable Lymphocyte Receptors
Wednesday, April 01 \| 5:00PM - 7:00PM Evolution of Pattern Recognition Molecules Room: Van Horne Ballroom A,B Speaker 2 of 4 Jules A. Hoffmann, Institute of Cellular and Molecular Biology, France Drosophila Pathogen Sensors
Wednesday, April 01 \| 5:00PM - 7:00PM Evolution of Pattern Recognition Molecules Room: Van Horne Ballroom A,B Speaker 3 of 4 Frederick M. Ausubel, Massachusetts General Hospital, USA Innate Immunity in C. elegans
Wednesday, April 01 \| 5:00PM - 7:00PM Evolution of Pattern Recognition Molecules Room: Van Horne Ballroom A,B Speaker 4 of 4 Qing Zhang, Sanford-Burnham Medical Research Institute, USA Short Talk: Direct Connector Genes Give Rise to Novel Topology of the Innate Immune Network in Amphioxus
Wednesday, April 01 \| 5:00PM - 7:00PM Regulation of Type I Interferon Production This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 5 * Giorgio Trinchieri, NCI, National Institutes of Health, USA
Wednesday, April 01 \| 5:00PM - 7:00PM Regulation of Type I Interferon Production This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 5 Keiko Ozato, NICHD, National Institutes of Health, USA Molecular Mechanism of Type I Interferon Transcription in Dendritic Cells
Wednesday, April 01 \| 5:00PM - 7:00PM Regulation of Type I Interferon Production This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 5 Elina I. Zuniga, University of California, San Diego, USA Short Talk: Persistent Virus Infection Inhibits Type I Interferon Production by Plasmacytoid Dendritic Cells to Facilitate Opportunistic Infections
Wednesday, April 01 \| 5:00PM - 7:00PM Regulation of Type I Interferon Production This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 5 Gunther Hartmann, Universitätsklinikum Bonn, Germany Ligands for RIG-I: Induction of IFN by siRNA
Wednesday, April 01 \| 5:00PM - 7:00PM Regulation of Type I Interferon Production This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 5 of 5 Wei Cao, UT MD Anderson Cancer Center, USA Short Talk: Identification of a Biological Ligand for Human Plasmacytoid Dendritic Cell Receptor ILT7
Wednesday, April 01 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Mezzanine 2
Wednesday, April 01 \| 7:30PM - 10:00PM Poster Session 3 Room: Mezzanine 2
Thursday, April 02 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Thursday, April 02 \| 7:00AM - 8:00AM Poster Setup Room: Mezzanine 2
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 1 of 7 * Daniel Kastner, National Institutes of Health, USA
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 2 of 7 Marco Colonna, Washington University School of Medicine, USA A Novel Signaling Pathway for Myeloid Cells Proliferation and Survival
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 3 of 7 Gordon D. Brown, University of Aberdeen, UK Lessons form Dectin-1: Insights Into Chronic Fungal Infection
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 4 of 7 Alan Sher, NIAID, National Institutes of Health, USA Th1/Th2 Polarizing Functions of Dendritic Cells in the Immune Response to Parasites
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 5 of 7 Christine A. Biron, Brown University, USA Changing Access to STATs in the Regulation of Type 1 IFN Effects on Immune Cell Subsets
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 6 of 7 Stephen M. Hedrick, University of California, San Diego, USA Short Talk: FoxO3 Controls the Magnitude of T Cell Immune Responses by Modulating Dendritic Cell Function
Thursday, April 02 \| 8:00AM - 11:15AM PRRs in Dendritic Cells and Macrophages (Joint) Room: Van Horne Ballroom Speaker 7 of 7 Nora A. Barrett, Brigham and Women's Hospital, USA Short Talk: Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells
Thursday, April 02 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Thursday, April 02 \| 11:15AM - 12:00PM Lunch Room: Mezzanine 2
Thursday, April 02 \| 12:00PM - 2:30PM Poster Session 4 Room: Mezzanine 2
Thursday, April 02 \| 12:00PM - 5:00PM Poster Viewing Room: Mezzanine 2
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 1 of 9 * Daniela I. Verthelyi, U.S. Food and Drug Administration, USA
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 2 of 9 John Vincent Forrester, University of Aberdeen, UK A Role for Dectin-1 in T-cell Mediated Autoimmune Inflammation
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 3 of 9 Seth L. Masters, Walter and Eliza Hall Institute, Australia Mutations Affecting The Interleukin-1 Receptor Antagonist (IL-1Ra) Cause A New Autoinflammatory Disease
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 4 of 9 Kathleen Azzam Smoak, NIEHS, National Institutes of Health, USA Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 5 of 9 Christophe M. Filippi, La Jolla Institute for Allergy and Immunology, USA Virus Utilizes TLR2 to Enhance CD4+CD25+ Regulatory T Cells in vivo and Confer them with Protective Capacity in Autoimmune Diabetes
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 6 of 9 Anna-Marie Fairhurst, Singapore Immunology Network, Singapore Innate Mechanisms in Autoimmunity
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 7 of 9 Menno P. J. de Winther, Academic Medical Center, Netherlands Myeloid Type I Interferon Signaling Promotes Atherogenesis
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 8 of 9 Li Wen, Yale University, USA The Role of Gut Flora through MyD88 in Type 1 Diabetes Development in NOD Mice
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 4: PAMP Sensors and Diseases Room: Van Horne Ballroom A,B Speaker 9 of 9 Jessica Gage, University of Ottawa Heart Institute, Canada Specific Loss of Toll-like Receptor 2 on Bone Marrow Derived Cells Decreases Atherosclerosis in LDL Receptor Null Mice
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 1 of 9 * Gwendalyn J. Randolph, Washington University, USA
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 2 of 9 Aymeric Rivollier, Lund University, Sweden Monocytes are Precursors of F4/80highCD11cint Macrophage-Like Cells and CD11chighF4/80int Dendritic Cells in the Mouse Colon
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 3 of 9 Michael D. Gunn, Duke University Medical Center, USA Blood-derived Inflammatory Dendritic Cells in Lymph Nodes Stimulate Acute Th1 Immune Responses
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 4 of 9 Guy Shakhar, Weizmann Institute of Science, Israel Visualizing DC Mobilization in the Skin of Live Mice Suggests how DCs Travel Inside Lymphatics and how Their Intravasation is Regulated
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 5 of 9 Emma Lo Kuan, Benaroya Research Institute, USA DC Trafficking from Perinodal Adipose Tissues to Lymph Nodes
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 6 of 9 Cherié L. Butts, Biogen Inc, USA Regulation of Dendritic Cell Function by Progesterone
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 7 of 9 Scott B. Drutman, New York University School of Medicine, USA Mature Dendritic Cells Exhibit a Broad Capacity for Antigen Capture and Presentation that can be Modulated by their Distribution
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 8 of 9 Marcin T. Kortylewski, Beckman Research Institute, City of Hope, USA Stat3 Targeting in Dendritic Cells Eliminates a Major Brake for TLR9 Agonist-Based Immunotherapy
Thursday, April 02 \| 2:30PM - 4:30PM Workshop 3: Differentiation, Trafficking and Function of DC This session is from Dendritic Cells Room: Van Horne Ballroom C Speaker 9 of 9 Nicolas Chevrier, Harvard University, USA Large Non-Coding RNAs: New Players in the Toll-like Receptor Pathways
Thursday, April 02 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Thursday, April 02 \| 5:00PM - 7:00PM SNPs, Clinical Diseases and Pattern Recognition Molecules/Se nsors Room: Van Horne Ballroom A,B Speaker 1 of 4 * Alan Sher, NIAID, National Institutes of Health, USA
Thursday, April 02 \| 5:00PM - 7:00PM SNPs, Clinical Diseases and Pattern Recognition Molecules/Se nsors Room: Van Horne Ballroom A,B Speaker 2 of 4 Adrian V. S. Hill, Jenner Institute, University of Oxford, UK Innate Immunity Polymorphisms and Susceptibility to Human Infectious Diseases
Thursday, April 02 \| 5:00PM - 7:00PM SNPs, Clinical Diseases and Pattern Recognition Molecules/Se nsors Room: Van Horne Ballroom A,B Speaker 3 of 4 Judy H. Cho, Icahn School of Medicine at Mount Sinai, USA NOD2, Innate Immunity and Human Diseases
Thursday, April 02 \| 5:00PM - 7:00PM SNPs, Clinical Diseases and Pattern Recognition Molecules/Se nsors Room: Van Horne Ballroom A,B Speaker 4 of 4 Daniel Kastner, National Institutes of Health, USA Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
Thursday, April 02 \| 5:00PM - 6:40PM Dendritic Cells in Cancer and Cancer Therapy This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 5 * Ralph M. Steinman, Rockefeller University, USA
Thursday, April 02 \| 5:00PM - 6:40PM Dendritic Cells in Cancer and Cancer Therapy This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 2 of 5 * Sebastian Amigorena, Institut Curie, France
Thursday, April 02 \| 5:00PM - 6:40PM Dendritic Cells in Cancer and Cancer Therapy This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 3 of 5 Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA Cancer Associated Dendritic Cells
Thursday, April 02 \| 5:00PM - 6:40PM Dendritic Cells in Cancer and Cancer Therapy This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 4 of 5 Guido Kroemer, Cordeliers Research Center, France Immunogenic Cell Death for Optimal Anti-Cancer Chemotherapy
Thursday, April 02 \| 5:00PM - 6:40PM Dendritic Cells in Cancer and Cancer Therapy This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 5 of 5 Carl G. Figdor, Radboud University Medical Center, Netherlands Human Plasmacytoid Dendritic Cells in Cancer and Cancer Therapy
Thursday, April 02 \| 6:40PM - 7:15PM Concluding Remarks This session is from Dendritic Cells Room: Van Horne Ballroom C, Shaughnessy/Beatty Speaker 1 of 1 Ralph M. Steinman, Rockefeller University, USA Dendritic Cells: Translating Innate to Adaptive Immunity to Help Discover Vaccines
Thursday, April 02 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mezzanine 2
Thursday, April 02 \| 8:15PM - 11:00PM Entertainment Room: Mezzanine 2
Thursday, April 02 \| 8:15PM - 11:00PM Cash Bar Room: Mezzanine 2
Friday, April 03 \| 10:25AM - 10:25AM Departure *Session Chair.