Web Desc
Dendritic Cells
joint with Pattern Recognition Molecules and Immune Sensors of Pathogens
Organizer(s): Giorgio Trinchieri, Gwendalyn J. Randolph and Sebastian Amigorena
Date: March 29 - April 03, 2009
Location: Fairmont Banff Springs, Banff, AB, Canada
Sponsored by Novo Nordisk A/S
Summary of Meeting:
The current studies on Dendritic Cells (DCs) have confirmed not only their major role as antigen presenting cells in adaptive immunity but also their important functions in the initiation of the innate resistance and inflammatory responses. Thus, DCs function as an important bridge between innate resistance and adaptive immunity either through cellular interactions or secretion of pro-inflammatory and immunoregulatory cytokines. The origin and migration pattern of DCs as well as their sharing of hematopoietic lineages, functions, and receptors with other phagocytic cell types such as monocytes and macrophages is a subject of intense investigation. The special characteristics of antigen processing and expression of immunoregulatory gene products in DCs are central in their ability to either activate or tolerize T cells and in their in vivo functions in degenerative, autoimmune and infectious diseases as well as in cancer. In this symposium, the following aspects of DC biology will be emphasized: (1) DC precursors and relation with monocyte and macrophages; (2) receptors, phagocytosis, and antigen presentation; (3) regulation of type I IFN production; (4) DCs in tolerance, immunity, and T cell activation; and (5) DCs in cancer and other diseases.
Scholarship Deadline: December 2 2008
Discounted Abstract Deadline: December 2 2008
Abstract Deadline: December 31 2008
Discounted Registration Deadline: January 29 2009
We gratefully acknowledge additional support for this conference from:
European Journal of Immunology
NIH funded, PRiME (Program for Research on Immune Modeling and Experimentation) initiative
Novo Nordisk A/SSociety for Mathematical Biology
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Cell PressRoyal Society of Chemistry
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI082769-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 29 | 3:00PM - 7:30PM
Registration
Room: Van Horne Foyer


Sunday, March 29 | 6:30PM - 7:30PM
Refreshments
Room: Van Horne Foyer


Sunday, March 29 | 7:30PM - 9:30PM
Keynote Session (Joint)
Room: Van Horne Ballroom

Speaker 1 of 4
* Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA

Sunday, March 29 | 7:30PM - 9:30PM
Keynote Session (Joint)
Room: Van Horne Ballroom

Speaker 2 of 4
* Giorgio Trinchieri, NCI, National Institutes of Health, USA

Sunday, March 29 | 7:30PM - 9:30PM
Keynote Session (Joint)
Room: Van Horne Ballroom

Speaker 3 of 4
Akira Shizuo, Osaka University, Japan
TLRs and Inflammation

Sunday, March 29 | 7:30PM - 9:30PM
Keynote Session (Joint)
Room: Van Horne Ballroom

Speaker 4 of 4
Ira Mellman, Genentech, Inc., USA
Cell Biology of Antigen Processing by Dendritic Cells

Monday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Monday, March 30 | 7:00AM - 8:00AM
Poster Setup
Room: Mezzanine 2


Monday, March 30 | 8:00AM - 11:30AM
Phagocytosis and Antigen Presentation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 6
* Ira Mellman, Genentech, Inc., USA

Monday, March 30 | 8:00AM - 11:30AM
Phagocytosis and Antigen Presentation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 6
Sebastian Amigorena, Institut Curie, France
A New Soluble Ligand of DCSign Present in Human Semen Inhibits HIV Trans-Infection of T Cells

Monday, March 30 | 8:00AM - 11:30AM
Phagocytosis and Antigen Presentation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 6
David G. Russell, Cornell University, USA
Reprogramming Phagosomal Function in Macrophages and Dendritic Cells

Monday, March 30 | 8:00AM - 11:30AM
Phagocytosis and Antigen Presentation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 6
Jose A. Villadangos, University of Melbourne, Australia
Antigen Presentation Specializations in the Dendritic Cell Network

Monday, March 30 | 8:00AM - 11:30AM
Phagocytosis and Antigen Presentation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 5 of 6
Romina S. Goldszmid, NCI, National Institutes of Health, USA
Short Talk: Host ER-Parasitophorous Vacuole Interaction Provides a Route of Entry for Antigen Cross-Presentation in Toxoplasma Infected Dendritic Cells

Monday, March 30 | 8:00AM - 11:30AM
Phagocytosis and Antigen Presentation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 6 of 6
Bali Pulendran, Stanford University School of Medicine, USA
Modulating Vaccine Responses with Innate Immunity

Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 8
* Siamon Gordon, Chang Gung University / University of Oxford, UK


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 8
Bruce A. Beutler, University of Texas Southwestern Medical Center, USA
Mutagenesis in the Analysis of Pathogen Sensing Pathways


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 8
Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
The IL-1 Receptor / Toll-Like Receptor Superfamily: 10 Years of Progress


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 8
Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA
A Mechanism of an Allergen-Induced Immune Response


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 8
Eicke Latz, University of Bonn, Germany
Pattern Recognition + Nalp3 Inflammasome


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 6 of 8
Sarah Ewald, Stanford University, USA
Short Talk: The Ectodomain of Toll-like Receptor 9 is Cleaved to Generate a Functional Receptor


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 7 of 8
Markus G. Manz, University Hospital Zürich, Switzerland
Short Talk: Human Bone Marrow Multipotent Mesenchymal Stromal Cells Sense TLR4-Agonists and Subsequently Enhance Myelopoiesis


Monday, March 30 | 8:00AM - 11:15AM
TLRs - I
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 8 of 8
Stephanie C. Eisenbarth, Yale University, USA
Short Talk: Activation of Adaptive Immunity but not Th2 Differentiation by the Nalp3 Inflammasome


Monday, March 30 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Monday, March 30 | 11:30AM - 12:30PM
Lunch
Room: Mezzanine 2


Monday, March 30 | 12:00PM - 2:30PM
Poster Session 1
Room: Mezzanine 2


Monday, March 30 | 12:00PM - 5:00PM
Poster Viewing
Room: Mezzanine 2


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 1 of 9
* Sebastian Amigorena, Institut Curie, France

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 2 of 9
Sofia Bogiatzi, Institut Curie, France
Reciprocal Inhibition of the TSLP and Th17 Immune Pathways

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 3 of 9
Anuradha Ray, University of Pittsburgh School of Medicine, USA
Dual c-kit-Stem Cell Factor Upregulation by Allergens in Dendritic Cells Promotes IL-6 but Limits IL-12 Impacting T Helper Cell Differentiation and Allergic Asthma

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 4 of 9
Thomas Duhen, Agonox, USA
Identification and Characterization of IL-22-Only Producing CD4+ T Cells: Role of Plasmacytoid DC for their Differentiation

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 5 of 9
Guillaume Hoeffel, Singapore Immunology Network, Singapore
HIV Antigen Crosspresentation Pathways from Apoptotic, Infected CD4+ T Cells, in Plasmacytoid Dendritic Cell

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 6 of 9
Roger V. Belizaire, Washington University in St. Louis, USA
Exogenous Antigen Enters the Major Histocompatibility Complex (MHC) Class I Processing and Presentation Pathway via Multiple Endocytic Compartments with Distinct Molecular and Proteolytic Requirements

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 7 of 9
Roberto A. Maldonado, Selecta Biosciences, USA
Rapamycin- and TGFbeta-Treated Dendritic Cells Induce Tolerance and de novo Differentiation of Regulatory T Cells in vitro and in vivo

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 8 of 9
Mireille H. Lahoud, Burnet Institute, Australia
Clec9A on the Surface of Dendritic Cells is a Dead Cell Recognition Molecule

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Antigen Presentation and T Cell Activation
Room: Van Horne Ballroom C

Speaker 9 of 9
David Sancho, CNIC-Fundación Centro Nacional de Investigaciones Cardiovasculares, Spain
Identification of a Dendritic Cell Receptor that Couples Sensing of Necrosis to Immunity

Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 8
Michael Carty, Trinity College Dublin, Ireland
Regulation of TRIF- dependent TLR Signaling by the Adaptor SARM


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 8
Ping Zhang, University of Alabama, Birmingham, USA
TLR2-dependent Modulation of Osteoclastogenesis by Porphyromonas gingivalis


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 8
Brendan J. Jenkins, Hudson Institute of Medical Research, Australia
Interplay between the Interleukin-6 Cytokine Family and Toll-like Receptors in Inflammation and Gastric Tumorigenesis


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 8
Jaime Pascual, Sanford-Burnham Medical Research Institute, USA
Molecular Mimicry in Innate Immunity: Crystal Structure of a Bacteria TIR Virulence Factor


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 8
Kathryn J. Moore, New York University Medical Center, USA
CD36 Ligands Promote Sterile Inflammation through Assembly of a TLR 4 and 6 Heterodimer


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 6 of 8
Emily L. Lowe, University of California, Los Angeles, USA
TLR2 is Protective in Colitis-associated Colorectal Cancer


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 7 of 8
Yue Guan, University of Illinois at Urbana-Champaign, USA
Human Toll-like Receptors 10 and 1 Share Common Mechanisms of Innate Immune Sensing but not Signaling


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: TLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 8 of 8
Anca Dorhoi, Friedrich-Loeffler-Institut, Germany
The Adaptor Protein CARD9 is Essential for Tuberculosis Control


Monday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Monday, March 30 | 5:00PM - 7:00PM
DCs in Tolerance, Immunity, and T Cell Differentiation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 5
* Bali Pulendran, Stanford University School of Medicine, USA

Monday, March 30 | 5:00PM - 7:00PM
DCs in Tolerance, Immunity, and T Cell Differentiation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 5
Daniel J. Cua, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
The IL-23/IL-17 Axis

Monday, March 30 | 5:00PM - 7:00PM
DCs in Tolerance, Immunity, and T Cell Differentiation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 5
Yong-Jun Liu, Sanofi, USA
Thymic Stromal Lymphopoietin Program Dendritic Cells to Induce TH2 Inflammation through a Unique Set of Signal Codes

Monday, March 30 | 5:00PM - 7:00PM
DCs in Tolerance, Immunity, and T Cell Differentiation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 5
Erica L. Granger, Pennsylvania State College of Medicine, USA
Short Talk: Persistence of MHC Class I-Restricted Antigen Presentation Following Acute Virus Infection Requires Direct and then Cross Presentation

Monday, March 30 | 5:00PM - 7:00PM
DCs in Tolerance, Immunity, and T Cell Differentiation
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 5 of 5
Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA
Tim-3 and Expansion of Regulatory Antigen Presenting Cells

Monday, March 30 | 5:00PM - 7:00PM
TLRs - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 5
* Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland


Monday, March 30 | 5:00PM - 7:00PM
TLRs - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 5
Siamon Gordon, Chang Gung University / University of Oxford, UK
Regulation of Macrophage Function by Surface Receptors and TH2 Cytokines


Monday, March 30 | 5:00PM - 7:00PM
TLRs - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 5
Ann Marshak-Rothstein, University of Massachusetts Medical School, USA
BCR, TLR and IFNaR Regulation of Autoreactive B Cells


Monday, March 30 | 5:00PM - 7:00PM
TLRs - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 5
Arthur M. Krieg, Checkmate Pharmaceuticals, USA
Therapeutic Usage of Nucleic Acid TLR Agonists


Monday, March 30 | 5:00PM - 7:00PM
TLRs - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 5
Wajahat Z. Mehal, Yale University, USA
Short Talk: Acetaminophen Induced Hepatotoxicity is Dependent on TLR7/9 and the NALP3 Inflammasome


Monday, March 30 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, March 31 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 7
* Gwendalyn J. Randolph, Washington University, USA

Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 7
Carlos Ardavin, National Center for Biotechnology, Spain
Monocyte-Derived Dendritic Cells

Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 7
Steffen Jung, Weizmann Institute of Science, Israel
Probing Origins and in vivo Functions of Dendritic Cells

Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 7
Markus G. Manz, University Hospital Zürich, Switzerland
Lymphoid-Organ Dendritic Cell Homeostasis in Steady-State and Inflammation

Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 5 of 7
Kang Liu, Columbia University Medical Center, USA
Short Talk: Dendritic Cell Development and Homeostasis in vivo

Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 6 of 7
Boris Reizis, New York University Langone Medical Center, USA
Plasmacytoid Dendritic Cell Differentiation

Tuesday, March 31 | 8:00AM - 11:15AM
Dendritic Cell Precursors
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 7 of 7
Florent Ginhoux, Singapore Immunology Network, Singapore
Short Talk: Flt3 and Id2-Dependent CD103+ DCs in Non-Lymphoid Tissues Form a Specific DC Lineage Related to Lymphoid CD8+ DCs

Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 7
* Jürg Tschopp, University of Lausanne, Switzerland


Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 7
Jonathan D.G. Jones, Sainsbury Laboratory, UK
Using Pathogen Effectors to Understand Host Resistance Mechanisms


Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 7
Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA
NLR in Diseases and Health


Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 7
Vishva M. Dixit, Genentech, Inc., USA
The Inflammasone: A Dynamic Caspase Activating Apparatus


Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 7
John C. Reed, Sanofi, France
Linking Innate Immunity with the Cell Death Machinery: Interactions of NLR and Bcl-2 Family Proteins


Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 6 of 7
Tara L. Roberts, Queensland Institute of Medical Research, Australia
Short Talk: The Role of HIN200 Family Proteins in the Response to Cytosolic DNA


Tuesday, March 31 | 8:00AM - 11:15AM
NLR/NBD-LRR Proteins, Pathways and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 7 of 7
Tsan Sam Xiao, Case Western Reserve University, USA
Short Talk: The Structure of NALP1/NLRP1 Leucine-rich Repeats Illustrates a Potential Ligand-binding Site


Tuesday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Tuesday, March 31 | 11:15AM - 11:15AM
On Own for Lunch


Tuesday, March 31 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Tuesday, March 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Tuesday, March 31 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Tuesday, March 31 | 5:00PM - 7:00PM
Recent Advances
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 4
* Maria Rescigno, Humanitas University, Italy

Tuesday, March 31 | 5:00PM - 7:00PM
Recent Advances
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 4
Dominique Kaiserlian, INSERM U851, France
Role of Liver Plasmacytoid DC in Oral Tolerance

Tuesday, March 31 | 5:00PM - 7:00PM
Recent Advances
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 4
Yvette van Kooyk, Vrije University Medical Center, Netherlands
Targeting of DC by Glycosylated Antigens

Tuesday, March 31 | 5:00PM - 7:00PM
Recent Advances
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 4
Ana-Maria Lennon-Duménil, Curie Institute, France
Coordinated Regulation of Antigen Presentation and Dendritic Cell Migration

Tuesday, March 31 | 5:00PM - 7:00PM
NLR/NBD-LRR Proteins, Pathways and Diseases - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 5
* Vishva M. Dixit, Genentech, Inc., USA


Tuesday, March 31 | 5:00PM - 7:00PM
NLR/NBD-LRR Proteins, Pathways and Diseases - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 5
Jürg Tschopp, University of Lausanne, Switzerland
Malarial Hemozoin is a Nalp3 Inflammasome Activating Danger Signal


Tuesday, March 31 | 5:00PM - 7:00PM
NLR/NBD-LRR Proteins, Pathways and Diseases - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 5
Gabriel Nuñez, University of Michigan, USA
Function of Nod-Like Receptors in Innate Immunity


Tuesday, March 31 | 5:00PM - 7:00PM
NLR/NBD-LRR Proteins, Pathways and Diseases - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 5
Dana Philpott, University of Toronto, Canada
Nod Proteins and the Interaction of Innate and Adaptive Immunity


Tuesday, March 31 | 5:00PM - 7:00PM
NLR/NBD-LRR Proteins, Pathways and Diseases - II
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 5
Koichi S. Kobayashi, Texas A&M Health Science Center, USA
Short Talk: The Role of Nod2-Rip2 Signaling Pathway in the Regulation of Commensal Microbiota in the Intestine


Tuesday, March 31 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2


Tuesday, March 31 | 7:30PM - 10:00PM
Poster Session 2
Room: Mezzanine 2


Wednesday, April 01 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 7
* Yong-Jun Liu, Sanofi, USA

Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 7
Miriam Merad, Mount Sinai School of Medicine, USA
Origin of Dendritic Cell Diversity Controls Tissue Immunity

Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 7
Gwendalyn J. Randolph, Washington University, USA
Monocytes, Dendritic Cells, and their Migration in Atherosclerosis

Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 7
Jerry Aldridge, St. Jude Children's Research Hospital, USA
Short Talk: tipDCs — The Necessary Evil of Lethal Influenza Infection

Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 5 of 7
Maria Rescigno, Humanitas University, Italy
DCs in Intestinal Disease

Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 6 of 7
Giorgio Trinchieri, NCI, National Institutes of Health, USA
TLR Signaling in DC: Lessons from Fibroblasts

Wednesday, April 01 | 8:00AM - 11:15AM
Dendritic Cells in Disease
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 7 of 7
Vanja Sisirak, Columbia University, USA
Short Talk: Breast Tumor Environment Alters Human Plasmacytoid Dendritic Cells Functions

Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 7
* Akira Shizuo, Osaka University, Japan


Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 7
Takashi Fujita, Institute for Frontier Life and Medical Sciences, Kyoto University, Japan
Solution Structures of MDA5 and LGP2 C-Terminal Domains: Identification of the RNA Recognition Loop in RIG-I Like Receptors


Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 7
Hong-Bing Shu, Wuhan University, China
Virus-Triggered Signaling Pathways


Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 7
Caetano Reis e Sousa, Francis Crick Institute, UK
Innate Anti-Viral Responses


Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 7
Kate A. Fitzgerald, University of Massachusetts Medical School, USA
Molecular Mechanisms of DNA Sensing


Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 6 of 7
Stephanie J. DeWitte-Orr, McMaster University, Canada
Short Talk: Scavenger Class A-Like Receptor (SLR): A Pathogen Recognition Receptor Mediating DsRNA-Induced Antiviral Responses


Wednesday, April 01 | 8:00AM - 11:15AM
Viral Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 7 of 7
Axel Kirchhofer, Gene Center, Germany
Short Talk: Structural and Functional Analysis of RIG-I Like Helicases


Wednesday, April 01 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Wednesday, April 01 | 11:15AM - 11:15AM
On Own for Lunch


Wednesday, April 01 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Wednesday, April 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: Systems Biology of Dendritic Cells

Suppor

ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative
Room: Shaughnessy/Beatty
The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells.
Speaker 1 of 6
Sonja I. Buschow, Nijmegen Centre for Molecular Life Sciences (NCMLS) St. Radboud UMC, Netherlands
DC-ATLAS: Dissecting Signal Transduction in the Dendritic Cell with a Systems Biology Approach

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: Systems Biology of Dendritic Cells

Suppor

ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative
Room: Shaughnessy/Beatty
The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells.
Speaker 2 of 6
Laszlo Nagy, Sanford-Burnham Medical Research Institute at Lake Nona, USA
Interrelated Nuclear Receptor Signaling Connects Lipids, the Genome and Immune Function in Dendritic Cells

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: Systems Biology of Dendritic Cells

Suppor

ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative
Room: Shaughnessy/Beatty
The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells.
Speaker 3 of 6
* Uri Hershberg, Drexel University, USA
Transcriptional Cascades in Dendritic Cells during Anti-Viral Responses

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: Systems Biology of Dendritic Cells

Suppor

ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative
Room: Shaughnessy/Beatty
The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells.
Speaker 4 of 6
Simeone Marino, University of Michigan Medical School, USA
Roles of Dendritic Cells in the Immune Response to Bacterial and Viral Infections

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: Systems Biology of Dendritic Cells

Suppor

ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative
Room: Shaughnessy/Beatty
The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells.
Speaker 5 of 6
Burkhard Ludewig, Kantonsspital St. Gallen, Switzerland
A Systems Immunological Approach to Plasmacytoid Dendritic Cell Function in Cytophatic Virus Infection

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: Systems Biology of Dendritic Cells

Suppor

ted by the Society for Mathematical Biology and the NIH-funded PRiME (Program for Research on Immune Modeling and Experimentation) Initiative
Room: Shaughnessy/Beatty
The immune system acts across multiple scales of space and time involving complex interactions and feedback. Computational modeling provides a framework to integrate observational data collected from multiple modes of experimentation and can provide insight into immune cell function in health and disease. Computational approaches have been increasingly applied to problems in immunology, providing methods that range from the inference of transcriptional programs to the prediction of drug treatment effects on viral dynamics. This workshop will cover recent advances and potential applications of computational modeling and methods to dendritic cells.
Speaker 6 of 6
Elodie Segura, Walter and Elizabeth Hall Institute, Australia
Novel Functional Specialization of Dendritic Cell Subsets Revealed by Plasma Membrane Comparative Proteomic Analysis

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 9
* Gordon D. Brown, University of Aberdeen, UK


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 9
Olaf Groß, Universitätsklinikum Freiburg, Germany
Adjuvanticity of the Synthetic Cord Factor Analog TDB for subunit M. tuberculosis Vaccination Requires Card9-dependent Innate Immune Activation


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 9
Tilmann Bürckstümmer, Haplogen Genomics, Austria
An Orthogonal Proteomic/Genomic Screen Identifies DSIRE as Cytoplasmic DNA Sensor for the Inflammasome


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 9
Paul G. Thomas, St. Jude Children's Research Hospital, USA
NLRP3 (NALP3/CIAS1/Cryopyrin) Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 9
Joseph A. Duncan, University of North Carolina, Chapel Hill, USA
Staphylococcus aureus a-hemolysin Induces IL-1B Production and Inflammatory Cell Death through Activation of Host NLRP3


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 6 of 9
Monique Willart, Ghent University, Belgium


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 7 of 9
Edward A. Miao, University of North Carolina at Chapel Hill, USA
NLRC4 is an Innate Immune Detector of the Bacterial Type III Secretion Apparatus


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 8 of 9
Takeshi Ichinohe, Yale University School of Medicine, USA
Inflammasome Recognition of Influenza Virus is Essential for Adaptive Immune Responses


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 2: NLR and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 9 of 9
Fengyi Wan, Johns Hopkins Bloomberg School of Public Health, USA
Ribosomal Protein S3: A Novel Non-Rel Subunit of NF-kappaB Confers Regulatory Specificity


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 1 of 8
* Tsan Sam Xiao, Case Western Reserve University, USA


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 2 of 8
William J. Kaiser, Emory University School of Medicine, USA
RHIM-dependent Control of NF-kappaB and Cell Death Activation via the DNA-dependent Activator of Interferon Regulatory Factors (DAI/ZBP1/DLM-1)


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 3 of 8
Pingwei Li, Texas A&M University, USA
The RIG-I Like Receptor LGP2 Recognizes the Termini of Double-Stranded RNA


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 4 of 8
Julien Pothlichet, Institut Pasteur, France
A Comprehensive Study of Human RIG-I Single-Nucleotide Polymorphisms (SNPs) Identifies Two Variants with a Major Functional Impact on Antiviral Host Response


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 5 of 8
Mehul S. Suthar, University of Washington, USA
The RLR Signaling Pathway is Essential in Triggering an Innate Immune Response to WNV Infection


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 6 of 8
Szu-Ting Chen, National Yang Ming University, Taiwan
CLEC5A, A Pattern Recognition Receptor to Flavivirus


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 7 of 8
Terry K. Means, Massachusetts General Hospital, USA
RNAi Identifies an Important Role for Scavenger Receptors in Fungal Immunity


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop 3: RLH and Other Pathogen Sensors
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom C

Speaker 8 of 8
Juergen M. Ruland, Technical University of Munich, Germany


Wednesday, April 01 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Wednesday, April 01 | 5:00PM - 7:00PM
Regulation of Type I Interferon Production
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 5
* Giorgio Trinchieri, NCI, National Institutes of Health, USA

Wednesday, April 01 | 5:00PM - 7:00PM
Regulation of Type I Interferon Production
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 5
Keiko Ozato, NICHD, National Institutes of Health, USA
Molecular Mechanism of Type I Interferon Transcription in Dendritic Cells

Wednesday, April 01 | 5:00PM - 7:00PM
Regulation of Type I Interferon Production
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 5
Elina I. Zuniga, University of California, San Diego, USA
Short Talk: Persistent Virus Infection Inhibits Type I Interferon Production by Plasmacytoid Dendritic Cells to Facilitate Opportunistic Infections

Wednesday, April 01 | 5:00PM - 7:00PM
Regulation of Type I Interferon Production
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 5
Gunther Hartmann, Universitätsklinikum Bonn, Germany
Ligands for RIG-I: Induction of IFN by siRNA

Wednesday, April 01 | 5:00PM - 7:00PM
Regulation of Type I Interferon Production
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 5 of 5
Wei Cao, UT MD Anderson Cancer Center, USA
Short Talk: Identification of a Biological Ligand for Human Plasmacytoid Dendritic Cell Receptor ILT7

Wednesday, April 01 | 5:00PM - 7:00PM
Evolution of Pattern Recognition Molecules
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 4
* Max D. Cooper, Emory University, USA
Evolution of LRR- Based Variable Lymphocyte Receptors


Wednesday, April 01 | 5:00PM - 7:00PM
Evolution of Pattern Recognition Molecules
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 4
Jules A. Hoffmann, Institute of Cellular and Molecular Biology, France
Drosophila Pathogen Sensors


Wednesday, April 01 | 5:00PM - 7:00PM
Evolution of Pattern Recognition Molecules
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 4
Frederick M. Ausubel, Massachusetts General Hospital, USA
Innate Immunity in C. elegans


Wednesday, April 01 | 5:00PM - 7:00PM
Evolution of Pattern Recognition Molecules
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 4
Qing Zhang, Sanford-Burnham Medical Research Institute, USA
Short Talk: Direct Connector Genes Give Rise to Novel Topology of the Innate Immune Network in Amphioxus


Wednesday, April 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2


Wednesday, April 01 | 7:30PM - 10:00PM
Poster Session 3
Room: Mezzanine 2


Thursday, April 02 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Thursday, April 02 | 7:00AM - 8:00AM
Poster Setup
Room: Mezzanine 2


Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 1 of 7
* Daniel Kastner, National Institutes of Health, USA

Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 2 of 7
Marco Colonna, Washington University School of Medicine, USA
A Novel Signaling Pathway for Myeloid Cells Proliferation and Survival

Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 3 of 7
Gordon D. Brown, University of Aberdeen, UK
Lessons form Dectin-1: Insights Into Chronic Fungal Infection

Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 4 of 7
Alan Sher, NIAID, National Institutes of Health, USA
Th1/Th2 Polarizing Functions of Dendritic Cells in the Immune Response to Parasites

Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 5 of 7
Christine A. Biron, Brown University, USA
Changing Access to STATs in the Regulation of Type 1 IFN Effects on Immune Cell Subsets

Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 6 of 7
Stephen M. Hedrick, University of California, San Diego, USA
Short Talk: FoxO3 Controls the Magnitude of T Cell Immune Responses by Modulating Dendritic Cell Function

Thursday, April 02 | 8:00AM - 11:15AM
PRRs in Dendritic Cells and Macrophages (Joint)
Room: Van Horne Ballroom

Speaker 7 of 7
Nora A. Barrett, Brigham and Women's Hospital, USA
Short Talk: Dectin-2 Recognition of House Dust Mite Triggers Cysteinyl Leukotriene Generation by Dendritic Cells

Thursday, April 02 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Thursday, April 02 | 11:15AM - 12:00PM
Lunch
Room: Mezzanine 2


Thursday, April 02 | 12:00PM - 2:30PM
Poster Session 4
Room: Mezzanine 2


Thursday, April 02 | 12:00PM - 5:00PM
Poster Viewing
Room: Mezzanine 2


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 1 of 9
* Gwendalyn J. Randolph, Washington University, USA

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 2 of 9
Aymeric Rivollier, Lund University, Sweden
Monocytes are Precursors of F4/80highCD11cint Macrophage-Like Cells and CD11chighF4/80int Dendritic Cells in the Mouse Colon

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 3 of 9
Michael D. Gunn, Duke University Medical Center, USA
Blood-derived Inflammatory Dendritic Cells in Lymph Nodes Stimulate Acute Th1 Immune Responses

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 4 of 9
Guy Shakhar, Weizmann Institute of Science, Israel
Visualizing DC Mobilization in the Skin of Live Mice Suggests how DCs Travel Inside Lymphatics and how Their Intravasation is Regulated

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 5 of 9
Emma Lo Kuan, Benaroya Research Institute, USA
DC Trafficking from Perinodal Adipose Tissues to Lymph Nodes

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 6 of 9
Cherié L. Butts, Biogen Inc, USA
Regulation of Dendritic Cell Function by Progesterone

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 7 of 9
Scott B. Drutman, New York University School of Medicine, USA
Mature Dendritic Cells Exhibit a Broad Capacity for Antigen Capture and Presentation that can be Modulated by their Distribution

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 8 of 9
Marcin T. Kortylewski, Beckman Research Institute, City of Hope, USA
Stat3 Targeting in Dendritic Cells Eliminates a Major Brake for TLR9 Agonist-Based Immunotherapy


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 3: Differentiation, Trafficking and Function of DC
Room: Van Horne Ballroom C

Speaker 9 of 9
Nicolas Chevrier, Harvard University, USA
Large Non-Coding RNAs: New Players in the Toll-like Receptor Pathways

Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 1 of 9
* Daniela I. Verthelyi, U.S. Food and Drug Administration, USA


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 2 of 9
John Vincent Forrester, University of Aberdeen, UK
A Role for Dectin-1 in T-cell Mediated Autoimmune Inflammation


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 3 of 9
Seth L. Masters, Walter and Eliza Hall Institute, Australia
Mutations Affecting The Interleukin-1 Receptor Antagonist (IL-1Ra) Cause A New Autoinflammatory Disease


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 4 of 9
Kathleen Azzam Smoak, NIEHS, National Institutes of Health, USA
Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 5 of 9
Christophe M. Filippi, La Jolla Institute for Allergy and Immunology, USA
Virus Utilizes TLR2 to Enhance CD4+CD25+ Regulatory T Cells in vivo and Confer them with Protective Capacity in Autoimmune Diabetes


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 6 of 9
Anna-Marie Fairhurst, Singapore Immunology Network, Singapore
Innate Mechanisms in Autoimmunity


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 7 of 9
Menno P. J. de Winther, Academic Medical Center, Netherlands
Myeloid Type I Interferon Signaling Promotes Atherogenesis


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 8 of 9
Li Wen, Yale University, USA
The Role of Gut Flora through MyD88 in Type 1 Diabetes Development in NOD Mice


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 4: PAMP Sensors and Diseases
This session is from Immune Pattern Recognition
Room: Van Horne Ballroom A,B

Speaker 9 of 9
Jessica Gage, University of Ottawa Heart Institute, Canada
Specific Loss of Toll-like Receptor 2 on Bone Marrow Derived Cells Decreases Atherosclerosis in LDL Receptor Null Mice


Thursday, April 02 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Thursday, April 02 | 5:00PM - 6:40PM
Dendritic Cells in Cancer and Cancer Therapy
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 5
* Ralph M. Steinman, Rockefeller University, USA

Thursday, April 02 | 5:00PM - 6:40PM
Dendritic Cells in Cancer and Cancer Therapy
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 2 of 5
* Sebastian Amigorena, Institut Curie, France

Thursday, April 02 | 5:00PM - 6:40PM
Dendritic Cells in Cancer and Cancer Therapy
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 3 of 5
Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA
Cancer Associated Dendritic Cells

Thursday, April 02 | 5:00PM - 6:40PM
Dendritic Cells in Cancer and Cancer Therapy
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 4 of 5
Guido Kroemer, Cordeliers Research Center, France
Immunogenic Cell Death for Optimal Anti-Cancer Chemotherapy

Thursday, April 02 | 5:00PM - 6:40PM
Dendritic Cells in Cancer and Cancer Therapy
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 5 of 5
Carl G. Figdor, Radboud University Medical Center, Netherlands
Human Plasmacytoid Dendritic Cells in Cancer and Cancer Therapy

Thursday, April 02 | 5:00PM - 7:00PM
SNPs, Clinical Diseases and Pattern Recognition Molecules/Se
nsors
This session is from Immune Pattern Recognition

Room: Van Horne Ballroom A,B

Speaker 1 of 4
* Alan Sher, NIAID, National Institutes of Health, USA


Thursday, April 02 | 5:00PM - 7:00PM
SNPs, Clinical Diseases and Pattern Recognition Molecules/Se
nsors
This session is from Immune Pattern Recognition

Room: Van Horne Ballroom A,B

Speaker 2 of 4
Adrian V. S. Hill, Jenner Institute, University of Oxford, UK
Innate Immunity Polymorphisms and Susceptibility to Human Infectious Diseases


Thursday, April 02 | 5:00PM - 7:00PM
SNPs, Clinical Diseases and Pattern Recognition Molecules/Se
nsors
This session is from Immune Pattern Recognition

Room: Van Horne Ballroom A,B

Speaker 3 of 4
Judy H. Cho, Icahn School of Medicine at Mount Sinai, USA
NOD2, Innate Immunity and Human Diseases


Thursday, April 02 | 5:00PM - 7:00PM
SNPs, Clinical Diseases and Pattern Recognition Molecules/Se
nsors
This session is from Immune Pattern Recognition

Room: Van Horne Ballroom A,B

Speaker 4 of 4
Daniel Kastner, National Institutes of Health, USA
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease


Thursday, April 02 | 6:40PM - 7:15PM
Concluding Remarks
Room: Van Horne Ballroom C, Shaughnessy/Beatty

Speaker 1 of 1
Ralph M. Steinman, Rockefeller University, USA
Dendritic Cells: Translating Innate to Adaptive Immunity to Help Discover Vaccines

Thursday, April 02 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Mezzanine 2


Thursday, April 02 | 8:15PM - 11:00PM
Entertainment
Room: Mezzanine 2


Thursday, April 02 | 8:15PM - 11:00PM
Cash Bar
Room: Mezzanine 2


Friday, April 03 | 10:25AM - 10:25AM
Departure


*Session Chair.