Web Desc
Developmental Origins and Epigenesis in Human Health and Disease
Organizer(s): Judith Swain, Peter D. Gluckman, Michael Meaney and Anne Ferguson-Smith
Date: April 26 - 30, 2010
Location: Swissotel The Stamford, Singapore, Singapore
In collaboration with Agency for Science, Technology and Research (A*STAR)
For important information on the coronavirus, please click here
Summary of Meeting:
Developmental plasticity results from the interplay of fetal environment and genetic factors. There is considerable data to indicate that these interactions play an important role in the susceptibility of the individual to the development of chronic diseases such as diabetes, obesity, and to the cognitive capacity of that individual. Evidence suggests that gene/environment interactions may result in epigenetic changes that not only indicate susceptibility to chronic disease, but may play a causative role in the processes. The specific nature of the signaling pathways that dictate these susceptibilities and capacities are not known. This symposium is designed to explore experimental models of development, to understanding the role of epigenetics in regulating important signaling pathways, and to examine the relationship of the fetal environment to normal development and the susceptibility to chronic disease.
Scholarship Deadline: December 28 2009
Discounted Abstract Deadline: December 28 2009
Abstract Deadline: January 29 2010
Discounted Registration Deadline: March 12 2010
We gratefully acknowledge additional support for this conference from:
Agency for Science, Technology and Research (A*STAR)Singapore Tourism Board


InKyeom Kim
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
American Society for Human GeneticsPubget Inc.
We gratefully acknowledge the generous grant for this conference provided by:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Grant No. 1R13HD065349-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Monday, April 26 | 3:00PM - 7:30PM
Registration
Room: Stamford Foyer


Monday, April 26 | 6:30PM - 7:30PM
Refreshments
Room: Stamford Foyer


Monday, April 26 | 7:30PM - 7:45PM
Opening Address and Welcoming Remarks
Room: Stamford Ballroom

Speaker 1 of 2
* Judith L. Swain, Singapore Institute for Clinical Sciences, Singapore

Monday, April 26 | 7:30PM - 7:45PM
Opening Address and Welcoming Remarks
Room: Stamford Ballroom

Speaker 2 of 2
Chuan Poh Lim, Chairman, Agency for Science Technology and Research (A*STAR), Singapore

Monday, April 26 | 7:45PM - 8:45PM
Keynote Address
Room: Stamford Ballroom

Speaker 1 of 2
* Anne C. Ferguson-Smith, University of Cambridge, UK

Monday, April 26 | 7:45PM - 8:45PM
Keynote Address
Room: Stamford Ballroom

Speaker 2 of 2
Adrian P. Bird, University of Edinburgh, UK
Investigating the Molecular Basis of Rett Syndrome

Tuesday, April 27 | 8:00AM - 9:00AM
Breakfast
Room: Stamford Ballroom


Tuesday, April 27 | 8:00AM - 9:00AM
Poster Setup
Room: Stamford Foyer


Tuesday, April 27 | 9:00AM - 12:00PM
Mechanisms of Developmental Plasticity
Room: Stamford Ballroom

Speaker 1 of 5
* Anne C. Ferguson-Smith, University of Cambridge, UK
Genomic Imprinting as an Adaptive Model of Developmental Plasticity

Tuesday, April 27 | 9:00AM - 12:00PM
Mechanisms of Developmental Plasticity
Room: Stamford Ballroom

Speaker 2 of 5
Stephen M. Cohen, Institute of Molecular and Cell Biology, Singapore
MicroRNA Functions: Insights from Drosophila Genetics

Tuesday, April 27 | 9:00AM - 12:00PM
Mechanisms of Developmental Plasticity
Room: Stamford Ballroom

Speaker 3 of 5
Emma Whitelaw, Queensland Institute of Medical Research, Australia
A New Model of Fetal Alcohol Spectrum Disordering in the Mouse

Tuesday, April 27 | 9:00AM - 12:00PM
Mechanisms of Developmental Plasticity
Room: Stamford Ballroom

Speaker 4 of 5
John S. Mattick, University of Oxford, UK
RNA as the Regulator of Epigenetic Memory and the Mediator of Epigenome-Environment Interactions

Tuesday, April 27 | 9:00AM - 12:00PM
Mechanisms of Developmental Plasticity
Room: Stamford Ballroom

Speaker 5 of 5
Kian Peng Koh, KU Leuven, Belgium
Short Talk: Tet1/Cxxc6 and Related Enzymes, a New Family of 5-Methylcytosine Hydroxylases, Modulate Pluripotency and Cell Lineage Specification in Mouse Embryonic Stem Cells

Tuesday, April 27 | 10:20AM - 10:40AM
Coffee Break
Room: Stamford Foyer


Tuesday, April 27 | 12:00PM - 1:00PM
Lunch
Room: Stamford Ballroom


Tuesday, April 27 | 12:00PM - 5:00PM
Poster Viewing
Room: Stamford Foyer


Tuesday, April 27 | 12:00PM - 2:30PM
Poster Session 1
Room: Stamford Foyer


Tuesday, April 27 | 2:30PM - 3:00PM
Coffee Available
Room: Stamford Foyer


Tuesday, April 27 | 3:00PM - 5:00PM
Phenotypic Plasticity in Evolution
Room: Stamford Ballroom

Speaker 1 of 4
* Russell D. Fernald, Stanford University, USA
Social Control of the Brain

Tuesday, April 27 | 3:00PM - 5:00PM
Phenotypic Plasticity in Evolution
Room: Stamford Ballroom

Speaker 2 of 4
Hamish G. Spencer, University of Otago, New Zealand
The Evolution of Phenotypic Plasticity: Insights from Theory

Tuesday, April 27 | 3:00PM - 5:00PM
Phenotypic Plasticity in Evolution
Room: Stamford Ballroom

Speaker 3 of 4
Diane Patricia Genereux, University of Washington, USA
Short Talk: Parent-Daughter Strand DNA Methylation Patterns: Snapshots of Epigenetic Processors

Tuesday, April 27 | 3:00PM - 5:00PM
Phenotypic Plasticity in Evolution
Room: Stamford Ballroom

Speaker 4 of 4
Yijun Ruan, The Jackson Laboratory for Genomic Medicine, USA
Short Talk: Estrogen Induced Chromatin Interaction and Transcription Regulation in Cancer Cells

Wednesday, April 28 | 8:00AM - 9:00AM
Breakfast
Room: Stamford Ballroom


Wednesday, April 28 | 8:00AM - 9:00AM
Poster Setup
Room: Stamford Foyer


Wednesday, April 28 | 9:00AM - 12:00PM
Developmental Influences in Chronic Disease
Room: Stamford Ballroom

Speaker 1 of 3
* Peter Gluckman, University of Auckland, New Zealand
The Developmental Contribution to the Risk of Chronic Disease

Wednesday, April 28 | 9:00AM - 12:00PM
Developmental Influences in Chronic Disease
Room: Stamford Ballroom

Speaker 2 of 3
Caleb E. Finch, University of Southern California, USA
Early Exposure to Infections Accelerates Aging

Wednesday, April 28 | 9:00AM - 12:00PM
Developmental Influences in Chronic Disease
Room: Stamford Ballroom

Speaker 3 of 3
Joseph H. Nadeau, Maine Medical Center Research Institute, USA
Transgenerational Epigenetic Control of Phenotypic Variation and Disease Risk

Wednesday, April 28 | 10:20AM - 10:40AM
Coffee Break
Room: Stamford Foyer


Wednesday, April 28 | 12:00PM - 1:00PM
Lunch
Room: Stamford Ballroom


Wednesday, April 28 | 12:00PM - 5:00PM
Poster Viewing
Room: Stamford Foyer


Wednesday, April 28 | 12:30PM - 2:30PM
Poster Session 2
Room: Stamford Foyer


Wednesday, April 28 | 2:30PM - 3:00PM
Coffee Available
Room: Stamford Foyer


Wednesday, April 28 | 3:00PM - 5:00PM
Neural and Developmental Epigenetics
Room: Stamford Ballroom

Speaker 1 of 3
* Michael Meaney, McGill University, Canada
Developmental Influences on Cognitive Processes

Wednesday, April 28 | 3:00PM - 5:00PM
Neural and Developmental Epigenetics
Room: Stamford Ballroom

Speaker 2 of 3
Yi Eve Sun, University of California, Los Angeles, USA
DNA Methylation and Neural Cell Fate

Wednesday, April 28 | 3:00PM - 5:00PM
Neural and Developmental Epigenetics
Room: Stamford Ballroom

Speaker 3 of 3
Zhao Xu, Beth Israel Deaconess Medical Center, USA
Pathway Discovery in Adipocyte Biology Using Epigenomics

Thursday, April 29 | 8:00AM - 9:00AM
Breakfast
Room: Stamford Ballroom


Thursday, April 29 | 9:00AM - 11:40AM
Environmental Control of Tissue Differentiation
Room: Stamford Ballroom

Speaker 1 of 4
Zofia Zukowska, University of Minnesota, USA
Gender-Specific Stress-Induced Programming for Obesity: Role of Neuropeptide Y and Adipose Stem Cells

Thursday, April 29 | 9:00AM - 11:40AM
Environmental Control of Tissue Differentiation
Room: Stamford Ballroom

Speaker 2 of 4
Davor Solter, Institute of Medical Biology, Singapore

Thursday, April 29 | 9:00AM - 11:40AM
Environmental Control of Tissue Differentiation
Room: Stamford Ballroom

Speaker 3 of 4
Judy C. Sng, Singapore Institute of Clinical Sciences, Singapore
Control of the Critical Period in Sensory Development

Thursday, April 29 | 9:00AM - 11:40AM
Environmental Control of Tissue Differentiation
Room: Stamford Ballroom

Speaker 4 of 4
* Jonathan R. Seckl, University of Edinburgh School of Clinical Sciences & Community Health, UK
Glucocorticoid 'Programming' of the Brain: From Stress to Liquorice

Thursday, April 29 | 10:20AM - 10:40AM
Coffee Break
Room: Stamford Foyer


Thursday, April 29 | 2:45PM - 3:00PM
Coffee Available
Room: Stamford Foyer


Thursday, April 29 | 3:00PM - 5:00PM
Environmental Factors and Developmental Plasticity
Room: Stamford Ballroom

Speaker 1 of 4
* Judith L. Swain, Singapore Institute for Clinical Sciences, Singapore

Thursday, April 29 | 3:00PM - 5:00PM
Environmental Factors and Developmental Plasticity
Room: Stamford Ballroom

Speaker 2 of 4
Michael K. Skinner, Washington State University, USA
The Environment and Epigenetics on Transgenerational Inheritance

Thursday, April 29 | 3:00PM - 5:00PM
Environmental Factors and Developmental Plasticity
Room: Stamford Ballroom

Speaker 3 of 4
Robert A. Waterland, Baylor College of Medicine, USA
The Search for Human Metastable Epialleles

Thursday, April 29 | 3:00PM - 5:00PM
Environmental Factors and Developmental Plasticity
Room: Stamford Ballroom

Speaker 4 of 4
Corrado Spadafora, Italian National Institute of Health, Italy
Retrotransposons, Reverse Transcriptase and the Genesis of New Genetic Information

Thursday, April 29 | 5:00PM - 7:00PM
Social Hour with Lite Bites
Room: Stamford Foyer


Friday, April 30 | 10:22AM - 10:22AM
Departure


*Session Chair
†Invited, not yet responded.