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This meeting took place in the past. Here is a list of meetings that are related:
Lipidomics and Bioactive Lipids in Metabolism and Disease (2017B6)
Systems Biology of Lipid Metabolism (2015B4)
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Web Desc
Bioactive Lipids: Biochemistry and Diseases
Organizer(s): Shuh Narumiya, Takao Shimizu and Garret A. FitzGerald
Date: June 06 - 11, 2010
Location: Westin Miyako Kyoto, Kyoto, Japan
Sponsored by Astellas Pharma Inc. and Takeda Pharmaceutical Company Limited. Also supported by the Japan Society for the Promotion of Science in cooperation with Kyoto University.
Summary of Meeting:
The world of lipid mediators is expanding. New and unexpected biological functions, biosynthetic pathways and receptors are being revealed for lipids as appreciation grows for their complex interactions with protein and the genome. New actions are still being added to classic mediators such as prostaglandins and leukotrienes. Lipid mediators are now recognized to influence a broad swath of biology from inflammation to allergy, immunity, cardiovascular diseases, cancer and behavior. Advances in lipidomics enable us to monitor dynamics of a variety of lipid mediators simultaneously. In this symposium we invite distinguished scientists to share their progress in this expanding field and to present a comprehensive view on what lipid mediators do in our body. We also invite scientists interested in the translation of such basic science from model systems to an understanding of the role of lipids in human physiology, disease and drug action. Expansion of our understanding of the role of lipid mediators affords the opportunity for novel therapeutic opportunities, examples of which will be discussed in the symposium.
Scholarship Deadline: February 23 2010
Discounted Abstract Deadline: February 23 2010
Abstract Deadline: March 9 2010
Discounted Registration Deadline: April 6 2010
We gratefully acknowledge additional support for this conference from:
Asubio Pharma Co., Ltd.
Journal of Lipid Research
Ono Pharmaceutical Co. Ltd.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Merck Research Laboratories
Minase Research Institute, Ono Pharmaceutical Co. Ltd.
Ono Pharmaceutical Co.Ltd.
Kuniyuki Kano
Keiko Yokota
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
We gratefully acknowledge the generous grant for this conference provided by:
National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI088818-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
Program
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Sunday, June 06
| 3:00PM - 7:30PM
Registration
Room: Mizuho Foyer
Sunday, June 06
| 6:30PM - 7:30PM
Refreshments
Room: Mizuho Foyer
Sunday, June 06
| 7:30PM - 8:30PM
Keynote Address
Room: Mizuho Ballroom
Speaker 1 of 2
*
Shuh Narumiya
, Kyoto University, Japan
Sunday, June 06
| 7:30PM - 8:30PM
Keynote Address
Room: Mizuho Ballroom
Speaker 2 of 2
Osamu Hayaishi
, Osaka Bioscience Institute, Japan
Prostaglandins and Sleep
Monday, June 07
| 7:30AM - 8:30AM
Breakfast
Room: Mizuho Ballroom
Monday, June 07
| 7:30AM - 8:30AM
Poster Setup
Room: Mizuho Ballroom
Monday, June 07
| 8:30AM - 7:00PM
Poster Viewing
Room: Mizuho Ballroom
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 1 of 8
*
Edward A. Dennis
, University of California, San Diego, USA
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 2 of 8
* Jesper Z. Haeggström
, Karolinska Institute, Sweden
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 3 of 8
Takao Shimizu
, University of Tokyo, Japan
Turnover of Glycerophospholipids by Deacylation-Reacylation Cycle
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 4 of 8
Makoto Murakami
, Tokyo Metropolitan Institute of Medical Science, Japan
Biological Functions of sPLA2s
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 5 of 8
Sasanka Ramanadham
, UAB Comprehensive Diabetes Center, USA
Involvement of Novel iPLA2beta-Dependent Mechanisms in beta-Cell Apoptosis
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 6 of 8
William L. Smith
, University of Michigan, USA
Cyclooxygenase Homodimers Function as Conformational Heterodimers with Allosteric and Catalytic Subunits
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 7 of 8
Michael H. Gelb
, University of Washington, USA
Short Talk: Phospholipase A2 Mediated Eicosanoid Generation During Inflammation
Monday, June 07
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism I
Room: Mizuho Ballroom
Speaker 8 of 8
Claude Wolf
, Faculté de Médecine St Antoine, France
Short Talk: Profiling of Liver Triglycerides Reveals Specific Molecular Species Associated with Fatty Liver in Mice
Monday, June 07
| 9:40AM - 10:00AM
Coffee Break
Room: Mizuho Foyer
Monday, June 07
| 12:00PM - 1:00PM
Lunch
Room: Mizuho Ballroom
Monday, June 07
| 12:30PM - 3:00PM
Poster Session 1
Room: Mizuho Ballroom
Monday, June 07
| 2:45PM - 3:00PM
Coffee Available
Room: Mizuho Foyer
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 1 of 8
*
Takao Shimizu
, University of Tokyo, Japan
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 2 of 8
*
William L. Smith
, University of Michigan, USA
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 3 of 8
Kikuko Watanabe
, Koshien University, Japan
A Novel Type of PGF Synthase belonging to the Thioredoxin-Like Superfamily
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 4 of 8
Jesper Z. Haeggström
, Karolinska Institute, Sweden
Structure and function of LTA4 hydrolase, LTC4 synthase, and related enzymes
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 5 of 8
B. Therese Kinsella
, University College Dublin, Ireland
Biochemistry of the Human Prostacyclin Receptor
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 6 of 8
Edward A. Dennis
, University of California, San Diego, USA
Short Talk: Lipidomics of Eicosanoids in Cell Signaling and Inflammation
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 7 of 8
Toshiko Suzuki-Yamamoto
, Okayama Prefectural University, Japan
Short Talk: Localization of Prostaglandin F2alpha Synthase and Receptor FP in the Rat Cerebellum
Monday, June 07
| 3:00PM - 5:30PM
Biochemistry of Lipid Metabolism II
Room: Mizuho Ballroom
Speaker 8 of 8
Marcia E. Newcomer
, Louisiana State University, USA
Short Talk: The Crystal Structure of Human 5-Lipoxygenase
Monday, June 07
| 5:30PM - 5:30PM
On Own for Dinner
Tuesday, June 08
| 7:30AM - 8:30AM
Breakfast
Room: Mizuho Ballroom
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 1 of 8
*
Jerold J. Chun
, The Scripps Research Institute, USA
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 2 of 8
* Kikuko Watanabe
, Koshien University, Japan
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 3 of 8
Robert C. Murphy
, University of Colorado Denver, USA
Transcellular Biosynthesis of Leukotrienes in vivo
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 4 of 8
Alan R. Brash
, Vanderbilt University Medical Center, USA
Lipoxygenases, Essential Fatty Acids, and the Epidermis
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 5 of 8
Helena Idborg
, Karolinska Institute, Sweden
Short Talk: Evaluation of Urinary Prostaglandin E2 Metabolite as a Biomarker of Inflammation
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 6 of 8
Michal L. Schwartzman
, New York Medical College, USA
Cytochrome P450-Derived EETs and HETEs in Vascular Biology
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 7 of 8
Junken Aoki
, Tohoku University, Japan
Autotaxin and LPA Signaling in Cardiovascular Development
Tuesday, June 08
| 8:30AM - 12:00PM
Biochemistry of Lipid Metabolism III
Room: Mizuho Ballroom
Speaker 8 of 8
Yutaka Yatomi
, Graduate School of Medicine, The University of Tokyo, Japan
Short Talk: Clinical Introduction of Plasma Lysophosphatidic Acid and Serum Autotaxin Assays
Tuesday, June 08
| 9:40AM - 10:00AM
Coffee Break
Room: Mizuho Foyer
Tuesday, June 08
| 12:00PM - 12:00PM
On Own for Lunch and Recreation
Tuesday, June 08
| 12:00PM - 1:00PM
Poster Setup
Room: Mizuho Ballroom
Tuesday, June 08
| 1:00PM - 9:30PM
Poster Viewing
Room: Mizuho Ballroom
Tuesday, June 08
| 3:45PM - 4:00PM
Coffee Available
Room: Mizuho Foyer
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 1 of 8
*
Andrew D. Luster
, Massachusetts General Hospital, USA
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 2 of 8
* Sarah Spiegel
, Virginia Commonwealth University, USA
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 3 of 8
Suzanne Ostrand-Rosenberg
, University of Maryland, USA
Prostaglandin E2 Drives Immune Suppression in the Tumor Microenvironment
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 4 of 8
Shuh Narumiya
, Kyoto University, Japan
Prostanoids and Immune Inflammation
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 5 of 8
Kenji Chiba
, Mitsubishi Tanabe Pharma Corporation, Japan
Immunoregulation by the Sphingosine 1-Phosphate Receptor Modulator, FTY720
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 6 of 8
Andreas Zimmer
, University of Bonn, Germany
Endocannabinoids and Immunoregulation
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 7 of 8
Doina Ganea
, Temple University School of Medicine, USA
Short Talk: Dendritic Cells – A Crucial Target for the Anti-Inflammatory Effects of Docosahexaenoic Acid (DHA)
Tuesday, June 08
| 4:00PM - 6:30PM
Immunoregulation
Room: Mizuho Ballroom
Speaker 8 of 8
Marc Stephan Lamphier
, Eisai Research Institute, USA
Short Talk: A Novel Antagonist of the Prostaglandin E2 Receptor EP4 Inhibits Th1 Differentiation and Th17 Expansion and is Orally Active in Arthritis Models
Tuesday, June 08
| 6:30PM - 7:30PM
Social Hour with Lite Bites
Room: Mizuho Ballroom
Tuesday, June 08
| 7:00PM - 9:30PM
Poster Session 2
Room: Mizuho Ballroom
Wednesday, June 09
| 7:30AM - 8:30AM
Breakfast
Room: Mizuho Ballroom
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 1 of 8
*
Shuh Narumiya
, Kyoto University, Japan
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 2 of 8
*
Colin D. Funk
, Queen's University, Canada
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 3 of 8
K. Frank Austen
, Harvard Medical School, USA
The Integrated Biology of the Cysteinyl Leukotrienes and their Receptors
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 4 of 8
Andrew D. Luster
, Massachusetts General Hospital, USA
Lipid-Cytokine-Chemokine Cascades Control Leukocyte Trafficking in Disease
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 5 of 8
Jilly F. Evans
, PharmAkea Therapeutics, USA
Development of FLAP Inhibitors
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 6 of 8
Sarah Spiegel
, Virginia Commonwealth University, USA
Novel Intracellular Targets of Sphingosine-1-Phosphate
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 7 of 8
Yumiko Imai
, National Institute of Biomedical Innovation, Japan
Short Talk: Hyper-Response of Innate Immune System Triggered by Oxidative Stress and Oxidized Phospholipids Controls the Severity of Acute Lung Injury
Wednesday, June 09
| 8:30AM - 12:00PM
Allergy and Inflammation
Room: Mizuho Ballroom
Speaker 8 of 8
Susanna Louise Lundström
, Karolinska Institutet, Sweden
Short Talk: Allergic Asthmatics Exhibit Altered Responses in Oxylipin Profile Compared to Healthy and Asthmatic Controls following Allergen Provocation
Wednesday, June 09
| 9:40AM - 10:00AM
Coffee Break
Room: Mizuho Foyer
Wednesday, June 09
| 12:00PM - 12:00PM
On Own for Lunch and Recreation
Wednesday, June 09
| 12:00PM - 1:00PM
Poster Setup
Room: Mizuho Ballroom
Wednesday, June 09
| 1:00PM - 9:30PM
Poster Viewing
Room: Mizuho Ballroom
Wednesday, June 09
| 3:45PM - 4:00PM
Coffee Available
Room: Mizuho Foyer
Wednesday, June 09
| 4:00PM - 5:50PM
Nervous System
Room: Mizuho Ballroom
Speaker 1 of 6
*
Garret A. FitzGerald
, University of Pennsylvania, USA
Wednesday, June 09
| 4:00PM - 5:50PM
Nervous System
Room: Mizuho Ballroom
Speaker 2 of 6
*
Yoshihiro Urade
, Osaka Bioscience Institute, Japan
Wednesday, June 09
| 4:00PM - 5:50PM
Nervous System
Room: Mizuho Ballroom
Speaker 3 of 6
Jerold J. Chun
, The Scripps Research Institute, USA
Lysophospholipid Signaling in Disease
Wednesday, June 09
| 4:00PM - 5:50PM
Nervous System
Room: Mizuho Ballroom
Speaker 4 of 6
Daniele Piomelli
, University of California, Irvine, USA
Endocannabinoids and the Brain
Wednesday, June 09
| 4:00PM - 5:50PM
Nervous System
Room: Mizuho Ballroom
Speaker 5 of 6
Shuntaro Hara
, Showa University, Japan
Short Talk: Involvement of Microsomal Prostaglandin E Synthase-1 (mPGES-1) in Alzheimer’s Disease
Wednesday, June 09
| 4:00PM - 5:50PM
Nervous System
Room: Mizuho Ballroom
Speaker 6 of 6
Fumiaki Kojima
, Asahikawa Medical College, Japan
Short Talk: Prostaglandin E2 Exacerbates Ischemic Brain Injury via the EP4 Receptor Subtype in Mice Subjected to a Middle Cerebral Artery Occlusion
Wednesday, June 09
| 5:50PM - 6:30PM
Cardiovascular Diseases I
Room: Mizuho Ballroom
Speaker 1 of 1
Shaun R. Coughlin
, University of California, San Francisco, USA
Sphingosine-1-Phosphate in the Plasma Compartment Regulates Basal and Stimulated Vascular Leak in Mouse
Wednesday, June 09
| 6:30PM - 7:30PM
Social Hour with Lite Bites
Room: Mizuho Ballroom
Wednesday, June 09
| 7:00PM - 9:30PM
Poster Session 3
Room: Mizuho Ballroom
Thursday, June 10
| 7:30AM - 8:30AM
Breakfast
Room: Mizuho Ballroom
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 1 of 8
*
Shaun R. Coughlin
, University of California, San Francisco, USA
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 2 of 8
* Michal L. Schwartzman
, New York Medical College, USA
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 3 of 8
Garret A. FitzGerald
, University of Pennsylvania, USA
Cardiovascular Biology of the Prostanoids
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 4 of 8
Colin D. Funk
, Queen's University, Canada
Eicosanoids in Cardiovascular Disease
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 5 of 8
Paola Patrignani
, G. D'Annunzio University, Italy
Role of Prostanoids in Endothelial Biology
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 6 of 8
Alison M. Strack
, Merck & Co., USA
Niacin and DP1 Antagonists: Studies in Mouse Models of Atherosclerosis
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 7 of 8
Barry Rubin
, Toronto General Hospital, Canada
Short Talk: Lack of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) in Bone Marrow Derived Leucocytes Impairs Left Ventricular Remodelling and Increases Mortality After Myocardial Infarction
Thursday, June 10
| 8:30AM - 12:00PM
Cardiovascular Diseases II
Room: Mizuho Ballroom
Speaker 8 of 8
Yoshinori Katsumata
, Keio University, Japan
Short Talk: Prostaglandin D2 Transduces Signals into Cardiomyocytes Independently of Canonical PGD2 Receptor
Thursday, June 10
| 9:40AM - 10:00AM
Coffee Break
Room: Mizuho Foyer
Thursday, June 10
| 12:00PM - 12:00PM
On Own for Lunch and Recreation
Thursday, June 10
| 3:45PM - 4:00PM
Coffee Available
Room: Mizuho Foyer
Thursday, June 10
| 4:00PM - 6:30PM
Immunomodulation by Lipid Mediators and Related Drugs
Room: Mizuho Ballroom
Speaker 1 of 6
* Jilly F. Evans
, PharmAkea Therapeutics, USA
Thursday, June 10
| 4:00PM - 6:30PM
Immunomodulation by Lipid Mediators and Related Drugs
Room: Mizuho Ballroom
Speaker 2 of 6
* Alison M. Strack
, Merck & Co., USA
Thursday, June 10
| 4:00PM - 6:30PM
Immunomodulation by Lipid Mediators and Related Drugs
Room: Mizuho Ballroom
Speaker 3 of 6
Yoshihiro Urade
, Osaka Bioscience Institute, Japan
PGD2 in Neuroinflammation and Muscular Dystrophy
Thursday, June 10
| 4:00PM - 6:30PM
Immunomodulation by Lipid Mediators and Related Drugs
Room: Mizuho Ballroom
Speaker 4 of 6
Takayuki Maruyama
, Ono Pharmaceutical Co.Ltd., Japan
Possibilities of EP Agonists and Antagonists for Novel Therapies
Thursday, June 10
| 4:00PM - 6:30PM
Immunomodulation by Lipid Mediators and Related Drugs
Room: Mizuho Ballroom
Speaker 5 of 6
David F. Woodward
, Allergan, Inc., USA
Short Talk: Design of Antagonists for PGF2alpha-Ethanolamide and PGE2-Glyceryl Ester by Using a Single Oxabicycloheptane Scaffold
Thursday, June 10
| 4:00PM - 6:30PM
Immunomodulation by Lipid Mediators and Related Drugs
Room: Mizuho Ballroom
Speaker 6 of 6
Masataka Majima
, Kitasato University School of Medicine, Japan
Short Talk: Recruitment of Mast Cells to the Tumor Microenvironment via the High Affinity Leukotriene B4 Receptor Regulates Tumor Stromal Profiles and Tumor-Associated Angiogenesis
Thursday, June 10
| 6:30PM - 7:30PM
Social Hour with Lite Bites
Room: Mizuho Ballroom
Thursday, June 10
| 6:30PM - 8:30PM
Entertainment
Room: Mizuho Ballroom
Friday, June 11
| 10:25AM - 10:25AM
Departure
*Session Chair.
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